CN202193780U - Electric sample introduction device - Google Patents

Electric sample introduction device Download PDF

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Publication number
CN202193780U
CN202193780U CN 201120279782 CN201120279782U CN202193780U CN 202193780 U CN202193780 U CN 202193780U CN 201120279782 CN201120279782 CN 201120279782 CN 201120279782 U CN201120279782 U CN 201120279782U CN 202193780 U CN202193780 U CN 202193780U
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CN
China
Prior art keywords
sample introduction
sample
semiconductor refrigerating
platform
introduction platform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn - After Issue
Application number
CN 201120279782
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Chinese (zh)
Inventor
高贯虹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHANGZHOU FUSHENG BIOTECHNOLOGY Co Ltd
Original Assignee
CHANGZHOU FUSHENG BIOTECHNOLOGY Co Ltd
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Priority to CN 201120279782 priority Critical patent/CN202193780U/en
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Publication of CN202193780U publication Critical patent/CN202193780U/en
Anticipated expiration legal-status Critical
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The utility model relates to an electric sample introduction device which comprises a sample introduction platform, a sample carrying platform, a semiconductor refrigerating and heating device, a temperature sensor, a radiator and a driving device for driving the sample introduction platform to do extending or retracting motion; the sample carrying platform is mounted on the sample introduction platform; the semiconductor refrigerating and heating device is arranged between the sample carrying platform and the sample introduction platform; a first heat exchange end surface of the semiconductor refrigerating and heating device faces towards the sample carrying platform; the temperature sensor is embedded in the sample introduction platform; and the second heat exchange end surface of the semiconductor refrigerating and heating device conducts heat through the radiator. The utility model provides an electric sample introduction device which can control temperature and can be linked with an automatic sample introduction manipulator connected externally.

Description

A kind of electrokinetic injection device
Technical field
The utility model relates to a kind of electrokinetic injection device, relates in particular to a kind of electrokinetic injection device, is applied to nucleic acid amplification and detection range, especially the nucleic acid amplification instrument of isothermal or temperature cycle.
Background technology
Present nucleic acid amplification instrument comprises the instrument that isothermal or temperature cycle, qualitative or real time fluorescent quantitative detect, and it all has the sample introduction platform of a sample.The form of sample introduction platform is divided into two kinds: a kind of is immovable fixedly sample introduction platform, and the user needs manual covered opening with the sample introduction platform, and the sample introduction platform is put in one or more example reactions pond; Lid is covered back, instrument could get into nucleic acid reaction and detect step again, and this fixed sample introduction platform characteristics are; During sample introduction, the temperature of sample introduction platform generally is controllable, thereby; The temperature of sample can be controlled effectively; Thereby guarantee some thermally sensitive sample unchangeability, but its deficiency is to be difficult to realize interlock with the mechanical manipulator of external automatic sampling, is not suitable for the requirement of the sample preparation of robotization.Another kind of be characterized in that for adopting the sample introduction platform of drawer type the sample introduction platform can stretch out automatically under power wheel drive in instrument, treat that sample is put into after, instrument is again with in sample introduction platform and the sample importing instrument; Automatically reach the mechanical manipulator interlock of open sample introduction platform and automatic sampling, thereby realize the sample preparation of robotization, the shortcoming of the sample introduction platform of this drawer type is; When the sample introduction platform stretches out, there is not temperature control, especially for the occasion of handling more sample; The sample introduction that the automatic sampling mechanical manipulator needs the long period to accomplish all samples is operated, therefore, and when sample introduction is operated; Sample possibly produce uncontrolled reaction, causes the discordance of nucleic acid amplification and detection, even failure.
The utility model content
The purpose of the utility model is to overcome the defective that prior art exists, and provides a kind of with electrokinetic injection device temperature controlled, that can realize interlock with external automatic sampling mechanical manipulator.
The utility model solves the technical scheme that its technical problem adopted: a kind of electrokinetic injection device; Comprise sample introduction platform, sample loading stage, semiconductor refrigerating heat-producing machine, TP, scatterer and be used to drive the sample introduction platform do stretch out, the drive unit of retraction movement; Said sample loading stage is installed on the sample introduction platform; Be provided with the semiconductor refrigerating heat-producing machine between said sample loading stage and the sample introduction platform; The first heat exchange end face of this semiconductor refrigerating heat-producing machine is towards the sample loading stage, and said TP is embedded in the sample loading stage, and the second heat exchange end face of said semiconductor refrigerating heat-producing machine is through scatterer heat conduction.
Said scatterer closely contacts with the second heat exchange end face of semiconductor refrigerating heat-producing machine, and both are connected on the sample introduction platform.
The first heat exchange end face of said semiconductor refrigerating heat-producing machine closely contacts with the bottom surface of sample loading stage.
Said drive unit comprises motor and the transmission mechanism that is connected with motor, and said sample introduction platform is connected with transmission mechanism.
Said transmission mechanism is feed screw nut transmission rig or Worm and worm-wheel gearing or belt wheel transmission rig or gear drive.
Said drive unit is linear electric motors, and these linear electric motors directly are connected with the sample introduction platform.
Said TP adopts RTD or thermistor or semiconductor transducer or thermopair.
The beneficial effect of the utility model: the utility model has solved the defective that exists in the background technology, adopts open sample introduction platform, can realize interlock with external automatic sampling mechanical manipulator; Refrigerating and heating device guarantees that sample keeps constant temperature in the sample introduction operating process, uncontrolled reaction can not take place, thereby guarantee follow-up nucleic acid amplification consistence and accuracy.
Description of drawings
Below in conjunction with accompanying drawing and embodiment the utility model is done further detailed explanation.
Fig. 1 is the structural representation of the preferred embodiment of the utility model.
Wherein: 1, sample introduction platform; 2, sample loading stage; 3, refrigerating and heating device; 4, TP; 5, scatterer; 6, drive unit; 6-1, motor; 6-2, transmission mechanism.
Embodiment
A kind of electrokinetic injection device as shown in Figure 1; Comprise sample introduction platform 1, sample loading stage 2, semiconductor refrigerating heat-producing machine 3, TP 4, scatterer 5 and be used to drive sample introduction platform 1 do stretch out, the drive unit 6 of retraction movement; Said sample loading stage 2 is installed on the sample introduction platform 1; Be provided with semiconductor refrigerating heat-producing machine 3 between said sample loading stage 2 and the sample introduction platform 1; The first heat exchange end face of said semiconductor refrigerating heat-producing machine 3 closely contacts with the bottom surface of sample loading stage 2, and said scatterer 5 is connected on the sample introduction platform 1, and said scatterer 5 closely contacts with the second heat exchange end face of semiconductor refrigerating heat-producing machine 3; Said TP 4 is embedded in the sample loading stage 2, is used for the temperature of test sample loading stage 2.
Said TP 4 is electrically connected with temperature regulator, and said temperature regulator is electrically connected with semiconductor refrigerating heat-producing machine 3.Said temperature regulator can temperature required per sample default settings temperature value, and controls semiconductor refrigerating heat-producing machine 3 refrigeration or heat according to the feedback temperature value of TP 4, sample loading stage 2 is reached and keeps preset temp.
Type of drive one: said drive unit 6 comprises motor 6-1 and the transmission mechanism 6-2 that is connected with motor 6-1, and said sample introduction platform 1 is connected with transmission mechanism 6-1, realizes stretching out and retraction movement.Said transmission mechanism 6-2 is feed screw nut transmission rig or Worm and worm-wheel gearing or belt wheel transmission rig or gear drive.
Type of drive two: said drive unit 6 is linear electric motors, and these linear electric motors directly are connected with sample introduction platform 1.
Said TP 4 adopts RTD or thermistor or semiconductor transducer or thermopair.
Should be appreciated that specific embodiment described above only is used to explain the utility model, and be not used in qualification the utility model.By the spirit conspicuous variation of being extended out of the utility model or change and still be among the protection domain of the utility model.

Claims (7)

1. electrokinetic injection device; It is characterized in that: comprise sample introduction platform (1), sample loading stage (2), semiconductor refrigerating heat-producing machine (3), TP (4), scatterer (5) and be used to drive sample introduction platform (1) do stretch out, the drive unit (6) of retraction movement; Said sample loading stage (2) is installed on the sample introduction platform (1); Be provided with semiconductor refrigerating heat-producing machine (3) between said sample loading stage (2) and the sample introduction platform (1); The first heat exchange end face of this semiconductor refrigerating heat-producing machine (3) is towards sample loading stage (2); Said TP (4) is embedded in the sample loading stage (2), and the second heat exchange end face of said semiconductor refrigerating heat-producing machine (3) is through scatterer (5) heat conduction.
2. a kind of electrokinetic injection device according to claim 1 is characterized in that: said scatterer (5) closely contacts with the second heat exchange end face of semiconductor refrigerating heat-producing machine (3), and both are connected on the sample introduction platform (1).
3. a kind of electrokinetic injection device according to claim 2 is characterized in that: the first heat exchange end face of said semiconductor refrigerating heat-producing machine (3) closely contacts with the bottom surface of sample loading stage (2).
4. a kind of electrokinetic injection device according to claim 3 is characterized in that: said drive unit (6) comprises motor (6-1) and the transmission mechanism (6-2) that is connected with motor (6-1), and said sample introduction platform (1) is connected with transmission mechanism (6-1).
5. a kind of electrokinetic injection device according to claim 4 is characterized in that: said transmission mechanism (6-2) is feed screw nut transmission rig or Worm and worm-wheel gearing or belt wheel transmission rig or gear drive.
6. a kind of electrokinetic injection device according to claim 3 is characterized in that: said drive unit (6) is linear electric motors, and these linear electric motors directly are connected with sample introduction platform (1).
7. a kind of electrokinetic injection device according to claim 3 is characterized in that: said TP (4) adopts RTD or thermistor or semiconductor transducer or thermopair.
CN 201120279782 2011-08-03 2011-08-03 Electric sample introduction device Withdrawn - After Issue CN202193780U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201120279782 CN202193780U (en) 2011-08-03 2011-08-03 Electric sample introduction device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201120279782 CN202193780U (en) 2011-08-03 2011-08-03 Electric sample introduction device

Publications (1)

Publication Number Publication Date
CN202193780U true CN202193780U (en) 2012-04-18

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Application Number Title Priority Date Filing Date
CN 201120279782 Withdrawn - After Issue CN202193780U (en) 2011-08-03 2011-08-03 Electric sample introduction device

Country Status (1)

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CN (1) CN202193780U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102911863A (en) * 2011-08-03 2013-02-06 常州福生生物技术有限公司 Electric sample feeding device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102911863A (en) * 2011-08-03 2013-02-06 常州福生生物技术有限公司 Electric sample feeding device
CN102911863B (en) * 2011-08-03 2015-12-09 常州福生生物技术有限公司 Electric sample introduction device

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C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Granted publication date: 20120418

Effective date of abandoning: 20151209

C25 Abandonment of patent right or utility model to avoid double patenting