CN102911863B - Electric sample introduction device - Google Patents
Electric sample introduction device Download PDFInfo
- Publication number
- CN102911863B CN102911863B CN201110220672.XA CN201110220672A CN102911863B CN 102911863 B CN102911863 B CN 102911863B CN 201110220672 A CN201110220672 A CN 201110220672A CN 102911863 B CN102911863 B CN 102911863B
- Authority
- CN
- China
- Prior art keywords
- sample introduction
- sample
- loading stage
- producing machine
- semiconductor refrigerating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The present invention relates to a kind of electric sample introduction device, comprise sample introduction platform, sample loading stage, semiconductor refrigerating heat-producing machine, temperature sensor, scatterer, and stretch out for driving sample introduction platform to do, the drive unit of retraction movement, described sample loading stage is arranged on sample introduction platform, semiconductor refrigerating heat-producing machine is provided with between described sample loading stage and sample introduction platform, first heat exchange end face of this semiconductor refrigerating heat-producing machine is towards sample loading stage, described temperature sensor is embedded in sample loading stage, second heat exchange end face of described semiconductor refrigerating heat-producing machine is by scatterer heat conduction.The invention provides a kind of with temperature controlled, the electric sample introduction device that links can be realized with external automatic sampling mechanical manipulator.
Description
Technical field
The present invention relates to a kind of electric sample introduction device, particularly relate to a kind of electric sample introduction device, be applied to nucleic acid amplification and detection field, especially the nucleic acid amplification instrument of isothermal or temperature cycle.
Background technology
Current nucleic acid amplification instrument, comprises isothermal or temperature cycle, instrument that qualitative or real time fluorescent quantitative detects, and it has the sample introduction platform of a sample.The form of sample introduction platform is divided into two kinds: one is immovable fixing sample introduction platform, user needs to be opened by the lid of sample introduction platform by hand, sample introduction platform is put in one or more example reaction pond, again lid lid is returned, instrument just can enter nucleic acid reaction and detecting step, this fixing sample introduction platform feature is, during sample introduction, the temperature of sample introduction platform is generally controllable, thus, the temperature of sample can be controlled effectively, thus ensure some thermally sensitive sample unchangeability, but its deficiency is difficult to realize linking with the mechanical manipulator of external automatic sampling, be not suitable for the requirement of the sample preparation of automatization.Another kind of for adopting the sample introduction platform of drawer type, be characterized in that sample introduction platform under power drive can from auto-extending in instrument, after sample is put into, instrument is again by sample introduction platform and Sample introduction instrument, automatic and open sample introduction platform and the mechanical manipulator of automatic sampling link, thus realize the sample preparation of automatization, the shortcoming of the sample introduction platform of this drawer type is, when sample introduction platform stretches out, temperature is not had to control, especially for the occasion of process compared with Multi-example, automatic sampling mechanical manipulator needs the long period to complete the sample introduction operation of all samples, therefore, when sample introduction operates, sample may produce uncontrolled reaction, cause the discordance of nucleic acid amplification and detection, even failed.
Summary of the invention
The object of the invention is to overcome the defect that prior art exists, provide a kind of with temperature controlled, the electric sample introduction device that links can be realized with external automatic sampling mechanical manipulator.
The technical solution adopted for the present invention to solve the technical problems is: a kind of electric sample introduction device, comprise sample introduction platform, sample loading stage, semiconductor refrigerating heat-producing machine, temperature sensor, scatterer, and stretch out for driving sample introduction platform to do, the drive unit of retraction movement, described sample loading stage is arranged on sample introduction platform, semiconductor refrigerating heat-producing machine is provided with between described sample loading stage and sample introduction platform, first heat exchange end face of this semiconductor refrigerating heat-producing machine is towards sample loading stage, described temperature sensor is embedded in sample loading stage, second heat exchange end face of described semiconductor refrigerating heat-producing machine is by scatterer heat conduction.
Second heat exchange end face close contact of described scatterer and semiconductor refrigerating heat-producing machine, and both are connected on sample introduction platform.
First heat exchange end face of described semiconductor refrigerating heat-producing machine and the bottom surface close contact of sample loading stage.
The transmission mechanism that described drive unit comprises motor and is connected with motor, described sample introduction platform is connected with transmission mechanism.
Described transmission mechanism is screw nut driven mechanism or Worm and worm-wheel gearing or belt wheel transmission mechanism or gear drive.
Described drive unit is linear electric motors, and these linear electric motors are directly connected with sample introduction platform.
Described temperature sensor adopts RTD or thermistor or semiconductor transducer or thermopair.
Beneficial effect of the present invention: the invention solves the defect existed in background technology, adopts open sample introduction platform, can realize with external automatic sampling mechanical manipulator linking; Refrigerating and heating device ensures that sample keeps constant temperature in sample introduction operating process, uncontrolled reaction can not occur, thus ensure follow-up nucleic acid amplification consistence and accuracy.
Accompanying drawing explanation
Below in conjunction with the drawings and specific embodiments, the present invention is further detailed explanation.
Fig. 1 is the structural representation of the preferred embodiments of the present invention.
Wherein: 1, sample introduction platform; 2, sample loading stage; 3, refrigerating and heating device; 4, temperature sensor; 5, scatterer; 6, drive unit; 6-1, motor; 6-2, transmission mechanism.
Embodiment
A kind of electric sample introduction device as shown in Figure 1, comprise sample introduction platform 1, sample loading stage 2, semiconductor refrigerating heat-producing machine 3, temperature sensor 4, scatterer 5, and stretch out for driving sample introduction platform 1 to do, the drive unit 6 of retraction movement, described sample loading stage 2 is arranged on sample introduction platform 1, semiconductor refrigerating heat-producing machine 3 is provided with between described sample loading stage 2 and sample introduction platform 1, first heat exchange end face of described semiconductor refrigerating heat-producing machine 3 and the bottom surface close contact of sample loading stage 2, described scatterer 5 is connected on sample introduction platform 1, second heat exchange end face close contact of described scatterer 5 and semiconductor refrigerating heat-producing machine 3, described temperature sensor 4 is embedded in sample loading stage 2, for detecting the temperature of sample loading stage 2.
Described temperature sensor 4 is electrically connected with temperature regulator, and described temperature regulator is electrically connected with semiconductor refrigerating heat-producing machine 3.Described temperature regulator can temperature required default settings temperature value per sample, and controls semiconductor refrigerating heat-producing machine 3 according to the feedback temperature value of temperature sensor 4 and freeze or heat, and makes sample loading stage 2 reach and maintain preset temp.
Type of drive one: the transmission mechanism 6-2 that described drive unit 6 comprises motor 6-1 and is connected with motor 6-1, described sample introduction platform 1 is connected with transmission mechanism 6-2, realizes stretching out and retraction movement.Described transmission mechanism 6-2 is screw nut driven mechanism or Worm and worm-wheel gearing or belt wheel transmission mechanism or gear drive.
Type of drive two: described drive unit 6 is linear electric motors, and these linear electric motors are directly connected with sample introduction platform 1.
Described temperature sensor 4 adopts RTD or thermistor or semiconductor transducer or thermopair.
Should be appreciated that specific embodiment described above only for explaining the present invention, being not intended to limit the present invention.Still be among protection scope of the present invention by spirit institute's apparent change of extending out of the present invention or change.
Claims (6)
1. an electric sample introduction device, it is characterized in that: comprise sample introduction platform (1), sample loading stage (2), semiconductor refrigerating heat-producing machine (3), temperature sensor (4), scatterer (5), and stretch out for driving sample introduction platform (1) to do, the drive unit (6) of retraction movement, described sample loading stage (2) is arranged on sample introduction platform (1), semiconductor refrigerating heat-producing machine (3) is provided with between described sample loading stage (2) and sample introduction platform (1), first heat exchange end face of this semiconductor refrigerating heat-producing machine (3) is towards sample loading stage (2), described temperature sensor (4) is embedded in sample loading stage (2), second heat exchange end face of described semiconductor refrigerating heat-producing machine (3) is by scatterer (5) heat conduction, second heat exchange end face close contact of described scatterer (5) and semiconductor refrigerating heat-producing machine (3), and both are connected on sample introduction platform (1).
2. electric sample introduction device according to claim 1, is characterized in that: the first heat exchange end face of described semiconductor refrigerating heat-producing machine (3) and the bottom surface close contact of sample loading stage (2).
3. electric sample introduction device according to claim 2, it is characterized in that: the transmission mechanism (6-2) that described drive unit (6) comprises motor (6-1) and is connected with motor (6-1), described sample introduction platform (1) is connected with transmission mechanism (6-2).
4. electric sample introduction device according to claim 3, is characterized in that: described transmission mechanism (6-2) is screw nut driven mechanism or Worm and worm-wheel gearing or belt wheel transmission mechanism or gear drive.
5. electric sample introduction device according to claim 2, is characterized in that: described drive unit (6) is linear electric motors, and these linear electric motors are directly connected with sample introduction platform (1).
6. electric sample introduction device according to claim 2, is characterized in that: described temperature sensor (4) adopts RTD or thermistor or semiconductor transducer or thermopair.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110220672.XA CN102911863B (en) | 2011-08-03 | 2011-08-03 | Electric sample introduction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110220672.XA CN102911863B (en) | 2011-08-03 | 2011-08-03 | Electric sample introduction device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102911863A CN102911863A (en) | 2013-02-06 |
| CN102911863B true CN102911863B (en) | 2015-12-09 |
Family
ID=47610445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110220672.XA Active CN102911863B (en) | 2011-08-03 | 2011-08-03 | Electric sample introduction device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102911863B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105773587A (en) * | 2016-03-28 | 2016-07-20 | 苏州倍特罗智能科技有限公司 | Discharging mechanical arm device used for high and low temperature test equipment |
| CN114778867A (en) * | 2022-06-13 | 2022-07-22 | 深圳市帝迈生物技术有限公司 | Sample detection device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2773682Y (en) * | 2005-03-15 | 2006-04-19 | 华南师范大学 | Automatic thermal desorption sampler with programmed temperature raising |
| CN202193780U (en) * | 2011-08-03 | 2012-04-18 | 常州福生生物技术有限公司 | Electric sample introduction device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2067424U (en) * | 1990-05-11 | 1990-12-12 | 中国科学院遗传研究所 | Polymerase chain reaction dna augmenting instrument |
-
2011
- 2011-08-03 CN CN201110220672.XA patent/CN102911863B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2773682Y (en) * | 2005-03-15 | 2006-04-19 | 华南师范大学 | Automatic thermal desorption sampler with programmed temperature raising |
| CN202193780U (en) * | 2011-08-03 | 2012-04-18 | 常州福生生物技术有限公司 | Electric sample introduction device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102911863A (en) | 2013-02-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018505660A5 (en) | ||
| AU2007290536B2 (en) | Rapid thermocycler | |
| KR20130100361A (en) | Thermal cycler and thermal cycle method | |
| JP2011503546A5 (en) | ||
| US20150321195A1 (en) | Temperature control devices and methods | |
| CN102911863B (en) | Electric sample introduction device | |
| EP2581122A3 (en) | Vacuum concentrator and method for vacuum concentration | |
| CN105372898B (en) | The control method of electric driven color-changing part | |
| JP2013252092A5 (en) | ||
| WO2017213590A4 (en) | Rapid thermal cycling for sample analyses and processing | |
| CN202193780U (en) | Electric sample introduction device | |
| CN100514244C (en) | Miniature fluid temperature controlling device and method thereof | |
| CN104029921B (en) | Micro constant-temperature case | |
| CN204939449U (en) | The portable PCR instrument of a kind of new microization | |
| JP6286539B2 (en) | Nucleic acid analyzer and device diagnostic method for nucleic acid analyzer | |
| CN206946338U (en) | A kind of temperature control device applied to nucleic acid amplification technologies | |
| CN103526300A (en) | Multifunctional crystal growing furnace | |
| CN203569233U (en) | Multifunctional crystal growth furnace | |
| CN201161198Y (en) | Thermostatic test-tube stand | |
| JP2011234693A5 (en) | ||
| CN201732426U (en) | Microwave heating device for automatic food processing vending machine | |
| CN204325370U (en) | Hand-held instant detection device | |
| CN106399087A (en) | Single-pore temperature switching device of molecular diagnosis system | |
| CN103049014A (en) | High-temperature circulator | |
| JP5896110B2 (en) | Thermal cycle device and control method for thermal cycle device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |