CN201935917U - reaction tube for immunity detection reactions - Google Patents
reaction tube for immunity detection reactions Download PDFInfo
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- CN201935917U CN201935917U CN201020692924XU CN201020692924U CN201935917U CN 201935917 U CN201935917 U CN 201935917U CN 201020692924X U CN201020692924X U CN 201020692924XU CN 201020692924 U CN201020692924 U CN 201020692924U CN 201935917 U CN201935917 U CN 201935917U
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- reaction tube
- solid phase
- reaction
- tube
- tube body
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Abstract
The utility model discloses a reaction tube with a transparent tube body. The reaction tube comprises the transparent tube body, a reaction liquid inlet is arranged at one end of the tube body, and a reaction liquid outlet is arranged at the other end of the tube body. A plurality of solid phase vectors with target antigens or target antibody peridia are arranged along the axial direction of the tube body, and adjacent solid phase vectors are separated by inert separating columns. By injecting reaction liquid into the reaction tube, immunity detection reactions which are based on developing theory to judge detection results and include a series of reactions such as incubation, wash, developing and the like can be led to be finished at a time through the reaction tube with no auxiliary instruments, and interpretation of the reaction tube is very convenient. The reaction tube is suitable for detection of samples with a small amount and external immunity detections of rural or remote regions where instruments supply or even stable electricity are not completely guaranteed.
Description
Technical field
The utility model relates to a kind of reaction tube that is used for the immune detection reaction.
Background technology
The immunodetection that is used for the classics of in-vitro diagnosis is enzyme linked immunosorbent assay (ELISA).The ultimate principle of ELISA method is, with enzymic-labelled antibody or antigen, and known antigen or antibody is adsorbed on surface of solid phase carriers, antigen-antibody reaction is carried out at surface of solid phase carriers, again with cleansing solution with the free composition eccysis in the liquid phase, act on behind the substrate colour developing by enzyme at last and judge testing result.ELISA method majority is to use ELISA Plate at present, generally is 96 orifice plates, detects different target antigens or target antibody.The advantage of this kind of enzyme target is to survey a plurality of patient's samples, can robotization, and shortcoming is for the situation that only detects one or two patient's sample, inconvenience is also impracticable.In addition, ELISA Plate has very strong dependence to instrument, washes plate machine, automatic irritated instrument etc., microplate reader etc., and all being needs standing equipment.This is for the vast rural area and the remote districts of China, and the area that do not guarantee fully as yet of instrument supply or even stable power especially is very inconvenience.For the experiment of only surveying small amount of sample, a kind of derivatization method of ELISA method is a film bar method.Film bar method is coated on multiple target antigen or target antibody on the film of cellulose nitrate, based on manual operations.Its shortcoming also is to need multiple supporting utility appliance, such as washing sample groove, concussion instrument etc.
Summary of the invention
Technical problem to be solved in the utility model is to overcome the deficiencies in the prior art, and a kind of reaction tube that is used for the immune detection reaction is provided, and it does not need supporting multiple utility appliance, and operation and interpretation are very convenient, especially is fit to the detection of small amount of sample.
For solving above technical matters, the utility model is taked following technical scheme:
A kind of reaction tube that is used for the immune detection reaction, comprise that an end has the reactant liquor import, the other end has the transparent tube body that reactant liquor exports, along a plurality of solid phase carriers of axially being provided with of body, separate by the inertia insulated column between the adjacent solid phase carrier in the body with target antigen or target antibody bag quilt.
Preferably, solid phase carrier is cylindrical and coaxial with body, and the outer wall of solid phase carrier and the inwall of body fit.
Preferably, insulated column is coaxial with body, and the diameter of insulated column is less than the diameter of solid phase carrier.
Preferably, described reaction tube also comprises the fixed head that extends axially and paste mutually with the outer wall of body along body.
Preferably, reactant liquor import and reactant liquor exit are equipped with lid.
Because the enforcement of above technical scheme, the utility model compared with prior art has following advantage:
The utility model has designed a kind of reaction tube with transparent tube body, along a plurality of solid phase carriers of axially being provided with of body with target antigen or target antibody bag quilt, by injection reaction liquid in reaction tube etc., make the immune detection reaction of judging testing result based on the colour developing principle, comprise hatch, clean, series reaction such as colour developing, can once finish by this reaction tube, need be by any supplementary instrument, and the interpretation of reaction tube is also very convenient, especially is fit to the detection of small amount of sample.
Description of drawings
The utility model is described in more detail below in conjunction with accompanying drawing and concrete embodiment:
Fig. 1 is the vertical view of the utility model reaction tube;
Fig. 2 is that the A-A of Fig. 1 is to cross section sectional structure synoptic diagram;
Wherein: 1, body; 10, reactant liquor import; 11, reactant liquor outlet; 2, solid phase carrier; 3, insulated column; 4, fixed head; 5, lid.
Embodiment
The utility model is described in more detail below in conjunction with specific embodiment, but be not limited to these embodiment.
According to reaction tube of the present utility model, be applicable to multiple immune detection reaction based on colour developing principle interpretation testing result.
Embodiment 1
As illustrated in fig. 1 and 2, reaction tube according to present embodiment, comprise that an end has reactant liquor import 10, the other end has reactant liquor and exports 11 transparent tube body 1, along a plurality of solid phase carriers 2 of axially being provided with of body 1, separate by inertia insulated column 3 between the adjacent solid phase carrier 2 in the body 1 with target antigen or target antibody bag quilt.Solid phase carrier 2 is cylindrical and coaxial with body 1, and the inwall of the outer wall of solid phase carrier 2 and body 1 fits.Insulated column 3 is also coaxial with body 1, and the diameter of insulated column 3 is less than the diameter of solid phase carrier 2.
According to present embodiment, described reaction tube also comprises the fixed head 4 that extends axially and paste mutually with the outer wall of body 1 along body 1.The effect of fixed head 4 is to make marks thereon or to label on the one hand, is convenient to staff's operation and interpretation; Fixed head 4 also can play and make body 1 place the effect that steadily waits on the other hand.
According to present embodiment; reactant liquor import 10 and reactant liquor export 11 places and are equipped with and cover 5, can charge into protection liquid in reaction tube when not using reaction tube, and on the two end cap with reaction tube; with the cleaning of protective reaction pipe inside and pure, prolong the serviceable life of reaction tube.
The reaction tube of present embodiment is applicable to the vitro detection reaction of euzymelinked immunosorbent assay (ELISA); during use the protection liquid of removing earlier in the reaction tube; the interior injected sample liquid of past again reaction tube also leaves standstill the process of hatching of finishing; inject cleaning fluid then successively; enzyme-labelled antigen or antibody liquid and substrate solution etc.; finish the substrate colour developing on solid phase carrier at last, and directly by visual inspection change color interpretation testing result.
Embodiment 2
The reaction tube structure of present embodiment is identical with embodiment 1.
The reaction of the immune detection of present embodiment is based on principle that the antigen-antibody reaction on the solid phase carrier exerts an influence to the pH value in the solution and comes the interpretation testing result, therefore can inject the pH indicator in the reaction tube at last and carry out interpretation as a result with the generation chromogenic reaction.
More than the utility model has been done detailed description; its purpose is to allow the personage that is familiar with this art can understand content of the present utility model and is implemented; can not limit protection domain of the present utility model with this; all equivalences of doing according to spirit of the present utility model change or modify, and all should be encompassed in the protection domain of the present utility model.
Claims (5)
1. one kind is used for the reaction tube that immune detection is reacted, it is characterized in that: described reaction tube comprises that an end has reactant liquor import (10), the other end has the transparent tube body (1) that reactant liquor exports (11), along a plurality of solid phase carriers (2) of axially being provided with of described body (1), separate by inertia insulated column (3) between the adjacent described solid phase carrier (2) in the described body (1) with target antigen or target antibody bag quilt.
2. reaction tube according to claim 1 is characterized in that: described solid phase carrier (2) is cylindrical and coaxial with described body (1), and the inwall of the outer wall of described solid phase carrier (2) and described body (1) fits.
3. reaction tube according to claim 1 and 2 is characterized in that: described insulated column (3) is coaxial with described body (1), and the diameter of described insulated column (3) is less than the diameter of described solid phase carrier (2).
4. reaction tube according to claim 1 is characterized in that: described reaction tube also comprises the fixed head (4) that extends axially and paste mutually with the outer wall of described body (1) along described body (1).
5. reaction tube according to claim 1 is characterized in that: described reactant liquor import (10) and described reactant liquor outlet (11) locate to be equipped with lid (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201020692924XU CN201935917U (en) | 2010-12-31 | 2010-12-31 | reaction tube for immunity detection reactions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201020692924XU CN201935917U (en) | 2010-12-31 | 2010-12-31 | reaction tube for immunity detection reactions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201935917U true CN201935917U (en) | 2011-08-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201020692924XU Expired - Lifetime CN201935917U (en) | 2010-12-31 | 2010-12-31 | reaction tube for immunity detection reactions |
Country Status (1)
| Country | Link |
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| CN (1) | CN201935917U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106990233A (en) * | 2017-05-27 | 2017-07-28 | 李晓燕 | A kind of convex bubble plate of immune detection |
| CN107155348A (en) * | 2014-09-27 | 2017-09-12 | 特雷西-艾比利蒂有限公司 | The system based on supporting plate for phenetic analysis thing |
| US10309947B2 (en) | 2013-02-27 | 2019-06-04 | Trace-Ability, Inc. | System and method for radiosynthesis, quality control and dose dispensing |
| US10895563B2 (en) | 2014-02-26 | 2021-01-19 | Trace-Ability, Inc. | Palette-based systems for analyte characterization |
| US11002717B2 (en) | 2014-02-26 | 2021-05-11 | Trace-Ability, Inc. | Systems and methods for characterizing radioactive analytes |
-
2010
- 2010-12-31 CN CN201020692924XU patent/CN201935917U/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10309947B2 (en) | 2013-02-27 | 2019-06-04 | Trace-Ability, Inc. | System and method for radiosynthesis, quality control and dose dispensing |
| US10895563B2 (en) | 2014-02-26 | 2021-01-19 | Trace-Ability, Inc. | Palette-based systems for analyte characterization |
| US11002717B2 (en) | 2014-02-26 | 2021-05-11 | Trace-Ability, Inc. | Systems and methods for characterizing radioactive analytes |
| US11846621B2 (en) | 2014-02-26 | 2023-12-19 | Trace-Ability, Inc. | Method of determining radiation characteristic of a sample |
| CN107155348A (en) * | 2014-09-27 | 2017-09-12 | 特雷西-艾比利蒂有限公司 | The system based on supporting plate for phenetic analysis thing |
| CN107155348B (en) * | 2014-09-27 | 2020-04-28 | 特雷西-艾比利蒂有限公司 | Pallet-based system for characterizing analytes |
| CN106990233A (en) * | 2017-05-27 | 2017-07-28 | 李晓燕 | A kind of convex bubble plate of immune detection |
| CN106990233B (en) * | 2017-05-27 | 2019-05-07 | 于宁 | A kind of convex bubble plate of immune detection |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: Suzhou City, Jiangsu Province, Suzhou Industrial Park 215123 Xinghu Street No. 218 BioBAY C6 building 101 Patentee after: Jiangsu Hao Bo biomedical Limited by Share Ltd Address before: Suzhou City, Jiangsu Province, Suzhou Industrial Park 215123 Xinghu Street No. 218 BioBAY C6 building 101 Patentee before: Suzhou Haooubo Biopharmaceutical Co., Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20110817 |