CN201885996U - Tester for benign and malignant tumors - Google Patents
Tester for benign and malignant tumors Download PDFInfo
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- CN201885996U CN201885996U CN2010201074457U CN201020107445U CN201885996U CN 201885996 U CN201885996 U CN 201885996U CN 2010201074457 U CN2010201074457 U CN 2010201074457U CN 201020107445 U CN201020107445 U CN 201020107445U CN 201885996 U CN201885996 U CN 201885996U
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Abstract
The utility model discloses an instrument which utilizes the modern biochemistry analysis technology to analyze and detect the concentration of a tumor marker-sodium ions in cells of a patient and diagnose benign and malignant tumors, and overcomes the defects of high cost of detecting equipment, serious trauma and damage on the body of the patient, long detection time and the like especially in the aspect of early discovering the malignant tumors quickly and accurately. The instrument not only can provide a detecting method with convenience and fast speed and low cost for patients, but also eliminates multiple unnecessary procedures such as various diagnostic tests, biopsy and complex invasive surgeries. The structure of the instrument adopts an integrated design, only a biochemistry detecting sensor needs to be connected to a signal input interface of the instrument in use, and corresponding operation can be carries out by a keyboard or a touch screen on operating equipment; and the detecting result is displayed on the screen of the equipment visually. The instrument is suitable for general survey and for being promoted and used in a clinic of a basic-level hospital, and brings gospel for potential cancer patients, especially wide tumor patients.
Description
Affiliated technical field
The utility model relates to a kind of device of good, malignant tumour quick diagnosis, especially fast, accurately, aspect the early detection malignant tumour, the clinical examination instrument that utilization modern biochemistry analytical technology detects tumour.
Background technology
At present, the good pernicious method of testing of known tumour is to extract pathological tissues, tumor markers is adopted means section pathology qualitative examinations such as serological method, Histological method, image analysis technology, adopt Medical Devices such as Electronic Speculum, CT, B ultrasonic to carry out assistant analysis and detect.But, adopt Medical Devices such as section pathologic finding and application CT, B ultrasonic to carry out not only apparatus expensive complicated operation of lesion detection, and interval between diagnosis length, high to doctor's experience requirement.To be multinational medical science men such as the Dr.P.Skehan of tumor research group, Dr.Alltila doctor Major of hospital of University of Geneva, Hungary tumour expert Dr.ZS.Nagy find and draw same conclusions lasting for two more than ten years in clinical trial and scientific research for school district, Texas, USA university San Antonio health sciences center people Dr.I.L.Cameron, Canadian Calgary university pharmacology, and sodium in the tumour cell, chlorine ion concentration will be apparently higher than normal other cells.And the Na ion concentration increase is directly proportional with tumour cell division speed in the cell.
Height in the cell of transformant (tumour cell) in the concentration ratio normal cell of sodion, the fireballing concentration height of same cell division than sodion in the slow cell of cell division.
Tumour cell (two kinds of hepatomas and two kinds of adenocarcinomas of breast), 451 ± 6 (S.E.); Corresponding non-canceration normal cell (mammary glandular cells of the liver cell of two species and two species), 138 ± 11; Quick somatoblast (small intestine and big enterocyte, neonatal cell, thymocyte) 196 ± 12; , divide cell (pancreatic cell, smooth muscle cell, liver cell etc.) slowly, 140 ± 8.The concentration of sodium will be apparently higher than normal other cells in the statistical results show, cancer cell.The fast cellular sodium ion concentration of split speed is significantly higher than split speed cell slowly, but significantly is lower than Na ion concentration in the tumour cell.Studies show that the chlorine ion concentration variation has identical pattern with the Na ion concentration variation in the cell.The nucleus that shows the same cell type simultaneously is identical with the concentration of intracytoplasmic sodion and chlorion.Never tenuigenin is with the interior various basic ion concentrations of nucleus and related revealed in the cell of reporting before a series of.In short, the sodium of higher concentration is relevant with cell mitogen with chlorine in the experimental data supportint cell, the sodium of the interior higher concentration of cell and chlorine and tumour obvious relation between persistence arranged.In addition, the potassium that raises in the cell and the concentration of magnesium, relevant with cell division activity ratio height, but with keep tumour cell mitosis activity ratio height and do not have positive connection.
Therefore the method for constituent content analysis such as the interior sodion of cell be can adopt, tumour cell and normal cell type,, malignant change optimum distinguished to differentiate.
Summary of the invention
In order to overcome existing lesion detection equipment price costliness, patient body to be caused deficiencies such as wound, infringement is big, detection time is long, the utility model provides a kind of measuring instrument, this instrument can not only be to patient's few detection method of quick expense of providing convenience, and can cancel the invasive surgical of many unnecessary programs such as multiple diagnostic test, biopsy and unnecessary complexity.
The technical scheme that its technical matters that solves the utility model adopts is: applying biological engineering in medicine expert and electronic technology expert painstaking effort for many years and up-to-date scientific payoffs, utilization modern biochemistry analytical technology is to patient's tumor markers---and sodium, chlorine plasma concentration are carried out the analyzing and testing of cytology level in the cell, and testing result has important clinical value to judging malignancy of tumor degree and prognosis.
The good pernicious tester of tumour, constitute by biochemistry detection sensor, signal condition module, signal processing module, terminal, signal condition module, signal processing module, terminal adopt integrated mounting means to be fixed in the incorporate cabinet, and the biochemistry detection sensor links to each other with incorporate cabinet by stube cable.Software comprises data acquisition process program module and computer applied algorithm module.Carry out corresponding operating by keyboard on the operating instrument or touch-screen, testing result shows on the screen of instrument intuitively.
Instrument is in clinical practice, the biochemistry detection sensor is directly contacted with the pathological tissue to be checked or the tumour of body surface, the sodion of electronic inductor and tissue produces chemical reaction in the sensor, produces faint electric signal, and it is strong and weak directly related with the concentration of sodion in the tissue.The electric signal that sensor produces is at first delivered to the signal condition module, the signal condition module adopt low noise, high performance low frequency operational amplifier to the feeble signal that sensor produces amplify, processing such as filtering, rectification, obtain a stable signal and supply with signal processing module.Signal processing module is handled by A/D change-over circuit and CPU and telecommunication circuit is formed, because CPU element can only processing digital signal, and is simulating signal through the signal that signal condition obtains, and therefore must carry out A/D to signal and change.Instrument adopts the precision height, and the A/D change-over circuit that reaction velocity is fast is guaranteed the technical feature of instrument.The cpu circuit cell signal is carried out calculation process, delivers to the serial communication port of terminal through the RS232 level shifting circuit.Terminal receives the sampled data that single-chip microcomputer sends by serial ports, after treatment, is presented on the user interface with the form of curve, numerical value.Simultaneously, system adopts database technology to preserve data such as patient information, testing result, and the user of service can access the history that has lane database by the data query interface and detect data.
The beneficial effects of the utility model are that the medical statistical analysis result of lesion detection instrument clinical trial is: susceptibility 〉=88.5%, accuracy 〉=89.8%, specificity 〉=90.5%.Expensive complex apparatus such as its comprehensive diagnos coincidence rate and CT, B ultrasonic are suitable, even better, and its price only is 1/5～1/3 of the said equipment.Be not only improvement, and be revolutionary innovation existing early diagnosis of tumor technology.Its easy easy-to-use, no wound, harmless, diagnostic accordance rate is higher than other expensive device, is suitable for generaI investigation and promotes the use of in basic hospital clinic, gives the potential cancer patient, especially vast tumor patient brings glad tidings.
Description of drawings
Below in conjunction with drawings and Examples the utility model is further specified.
Fig. 1 is a structured flowchart of the present utility model.
Fig. 2 is the principle of work block diagram of instrument.
Fig. 3 is the terminal software flow pattern.
Fig. 4 is the instrument probe structural drawing.
Embodiment
In Fig. 1, instrument hardware comprises that signal condition module, signal processing module, terminal adopt integrated mounting means to be fixed in the incorporate cabinet, and the special test software that installs instruments.The biochemistry detection sensor links to each other with incorporate cabinet by stube cable.Because biochemistry detection transducer sensitivity height, reaction velocity are fast, be to guarantee precision of test result and measuring accuracy, new biochemistry detection sensor is used in each test suggestion.
In Fig. 2,1. biochemistry detection sensor: its adopts modern biochemistry analytical technology, the electronic inductor of sensor contacts with sodion in the pathological tissue and produces chemical reaction, and this quick, sensitive chemical reaction produces the height that faint electric signal will show sodium ions content concentration in the pathological tissue.2. signal condition: adopt low noise, high performance low frequency operational amplifier to the feeble signal that sensor produces amplify, processing such as filtering, rectification, obtain a stable signal and supply with the A/D change-over circuit and handle.3. A/D change-over circuit: because CPU element can only processing digital signal, and be simulating signal, therefore must carry out the A/D conversion to signal through the signal that signal condition obtains.Characteristics such as the A/D change-over circuit that this instrument adopts has the precision height, and reaction velocity is fast have been guaranteed the technical feature of instrument.4. CPU handles and communicates by letter: this instrument adopts 51 ripe, stable series monolithics, and A/D conversion back digital signal samples is handled, and sends the data to terminal by serial ports.5. Computer Processing with communicate by letter: terminal receives the sampled data that single-chip microcomputer sends by serial ports, after treatment, is presented on the user interface with the form of curve, numerical value.6. patient information: mainly import information such as patient's name, admission number, testing result.7. testing result:, show the user interface of measurement result with the form of curve, numerical value.8. data are preserved: system adopts database technology to preserve data such as patient information, testing result.9. data query: the user can access the history that has lane database by the data query interface and detect data.
In Fig. 3, after system powered on, computing machine was in password input waiting status, after the input password is correct, enters system master interface, and mainly comprise: the patient information interface is used for mainly importing information such as patient's name, admission number, testing result; The testing result interface shows the user interface of measurement result with the form of curve, numerical value; Data are preserved the interface, and system adopts database technology to preserve data such as patient information, testing result; The data query interface, the user can access the history that has lane database by the data query interface and detect data.
In Fig. 4,1 be probe electrode just, 2 is negative for probe electrode, 3 are the probe shield layer, 4 is outer probe, 5 is the connecting line negative terminal, 6 is the connecting line anode.
Claims (1)
1. good pernicious tester of tumour, constitute by biochemistry detection sensor, signal condition module, signal processing module, terminal, it is characterized in that: signal condition module, signal processing module, terminal adopt integrated mounting means to be fixed in the incorporate cabinet, signal processing module is handled by A/D change-over circuit and CPU and telecommunication circuit is formed, and the biochemistry detection sensor links to each other with incorporate cabinet by stube cable.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201074457U CN201885996U (en) | 2010-02-04 | 2010-02-04 | Tester for benign and malignant tumors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201074457U CN201885996U (en) | 2010-02-04 | 2010-02-04 | Tester for benign and malignant tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201885996U true CN201885996U (en) | 2011-06-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2010201074457U Expired - Fee Related CN201885996U (en) | 2010-02-04 | 2010-02-04 | Tester for benign and malignant tumors |
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| CN (1) | CN201885996U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105331534A (en) * | 2015-09-18 | 2016-02-17 | 孙月 | Instrument and method for separating parasitic pathogenic microorganisms in cells |
-
2010
- 2010-02-04 CN CN2010201074457U patent/CN201885996U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105331534A (en) * | 2015-09-18 | 2016-02-17 | 孙月 | Instrument and method for separating parasitic pathogenic microorganisms in cells |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: QINHUANGDAO GAHA ELECTRONIC INSTRUMENT CO., LTD. Free format text: FORMER OWNER: ZHANG XIN Effective date: 20120120 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 075061 ZHANGJIAKOU, HEBEI PROVINCE TO: 066102 QINHUANGDAO, HEBEI PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20120120 Address after: 066102, Beidaihe District, Qinhuangdao town of small Mint village, No. 2 North Street Patentee after: Qinhuangdao Gaha Electronic Instrument Co. Ltd. Address before: 1, unit 137, 075061 West Shahe Avenue, Shiqiao West, Hebei, Zhangjiakou, 702 Patentee before: Zhang Xin |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110629 Termination date: 20150204 |
|
| EXPY | Termination of patent right or utility model |