CN109091113A - A kind of mild cognitive impairment diagnostic device and data processing equipment - Google Patents
A kind of mild cognitive impairment diagnostic device and data processing equipment Download PDFInfo
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Abstract
The invention proposes a kind of mild cognitive impairment diagnostic devices, including complete machine frame, information collecting device, test and analyze device, touch screen and mild cognitive impairment diagnostic data processing unit, the mild cognitive impairment diagnostic data processing unit is used to judge the constitution type in TCM of the user, judge the serum Hcy content and serum of the user, urine 8-iso-PGF 2a content results, judge the NAA/Cr ratio result of the bilateral hippocampus of the user, receive the interrogation result for the user that microphone is sent, and the constitution type in TCM according to the user, serum Hcy content and serum, urine 8-iso-PGF 2a content results, the NAA/Cr ratio result and interrogation result of bilateral hippocampus generate the diagnostic assessment report of the user.Apparatus of the present invention are easy to operate, judgement is accurate, are readily transported and store, and cost is relatively low, it is easy to accomplish industrial application.
Description
Technical field
The present invention relates to the field of medical instrument technology, and in particular to a kind of mild cognitive impairment diagnostic device and data processing
Device.
Background technique
21 century China has stepped into aging society, mild cognitive impairment (Mild cognitive impairment,
MCI) it is a kind of clinical state between normal aging and early stage dementia, is annual 10%- to dull-witted conversion ratio
15%, about 80% MCI patient has been converted into dementia when by the 6th year, therefore is particularly important to the therapeutic intervention of MCI.So
And most MCI patients do not draw attention to this disease, and at home, and since cognition inspection method is different, the diagnostic criteria of MCI
Dispute is always existed, therefore most MCI patients fail to obtain getting up early intervention in time.
Currently, the diagnosis of MCI has scholar to answer recently mostly using Mini-Mental animation scale (MMSE) as screening instruments
Cognitive Function is carried out with Montreal scale (MoCA), it is found that it early diagnoses sensibility, the specificity of MCI and is superior to
MMSE.In terms of biological marker, such as combines and MCI early stage also will be helpful to the detection of homocysteine (Hcy)
Diagnosis and early treatment.Magnetic Resonance Spectrum (magnetic resonance spectroscopy, MRS) imaging technique is as mesh
Preceding unique one kind is capable of the iconography skill of the energetic supersession of Non-invaive examination living tissue, biochemical change and compound quantitative analysis
Art is also applied in the research of MCI.In treatment, continued to use mostly to drug used in dementia, including anticholinesterase, cigarette
Alkali agonist, omega-fatty acid etc..
In the diagnosis of MCI, most common cognitive function Screening Scale is Mini Mental State inspection (MMSE),
It is higher but poor to the specificity and sensibility of MCI or non-dementia Cognitive function damage to the specificity of screening dementia.Clinically root
According to experience, Montreal cognition assessment (MoCA) scale has been formulated in improvement on the basis of MMSE, is mainly used for having cognitive function barrier
Hinder main suit, MMSE scores in the elderly of normal range (NR).But MoCA scale there is now 6 since 2006 are introduced into China
Version, the MoCA scale that different regions use are not unified, may diagnosis to MCI it is variant.In addition, existing clinical using to serum
The detection and magnetic resonance spectrum imaging check-up of homocysteine (Hcy) carry out auxiliary diagnosis MCI, but do not have and specifically face
Dividing value guidance is clinical.It is continued to use mostly in existing treatment to drug used in dementia, most of patients worries Western medicine side effect, and treatment side
Case is single, does not carry out physique assessment to MCI patient.And close ties are had according to the elaboration of theory of traditional Chinese medical science, constitution and clinical disease,
Neurological susceptibility, characteristic of disease and the treatment etc. of constitution difference decision clinical disease.It can be seen that at present clinically to the diagnosis of MCI patient
And therapeutic scheme is not perfect, but still lacks system, efficient, safe and simple diagnostic device.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of mild cognitive impairment diagnostic device and data processing dress
It sets, it is intended that a kind of mild cognitive impairment diagnostic device is provided, it being capable of system, efficient, safe and simple judgement user
Cognitive assessment, for diagnosing mild cognitive impairment, to user's early intervention treatment play the role of it is very big, help user avoid sending out
It transforms into as the cognitive disorders such as senile dementia disease.
The present invention provides a kind of mild cognitive impairment diagnostic device, including complete machine frame, information collecting device, detection and analysis
Device, touch screen and mild cognitive impairment diagnostic data processing unit,
The complete machine frame is for carrying the touch screen, testing and analyzing device and information collecting device and mild cognitive barrier
Hinder diagnostic data processing unit；
The information collecting device includes for acquiring the blood-taking device of user's limosis vein blood, for acquiring user's urine
Device, using 3.0T Siemens's superconducting magnetic resonance imaging system to user carry out multi-voxel proton wave spectrum collection result input terminal
And the microphone for carrying out interactive voice with doctor of traditional Chinese medicine；
The device that tests and analyzes is used to contain the user's limosis vein blood progress Hcy content and 8-iso-PGF 2a of acquisition
Amount is analyzed and user's urine for that will acquire carries out 8-iso-PGF 2a content analysis；
The information collecting device, detection and analysis device, microphone and touch screen are diagnosed with the mild cognitive impairment
Data processing equipment electrical connection；
The mild cognitive impairment diagnostic data processing unit is used to judge the use according to the user information that touch screen acquires
The constitution type in TCM at family judges the homocysteine of the user according to user's limosis vein blood that blood-taking device acquires
(Hcy) content and the different Prostaglandin F2a of 8- (8-iso-PGF 2a) content results are sentenced according to user's urine that urine sampling device acquires
Break the urine 8-iso-PGF 2a content results of the user, according to the neuron mediator magnetic resonance of user's bilateral hippocampus of input
Pop metabolic information judges the NAA/Cr ratio of the bilateral hippocampus of the user as a result, receiving the interrogation for the user that microphone is sent
As a result, and according to the constitution type in TCM of the user, serum Hcy content and 8-iso-PGF 2a content results, urine 8-
Iso-PGF 2a content results, N- Acetyl Aspartate (NAA)/creatine (Cr) ratio result of bilateral hippocampus and interrogation knot
Fruit generates the diagnostic assessment report of the user.
As further improvement of the invention, information type includes tcm constitution information, interrogation information, limosis vein blood
Hcy content and 8-iso-PGF 2a content information, urine 8-iso-PGF 2a content information, bilateral hippocampus NAA/Cr ratio letter
Breath.
As further improvement of the invention, interrogation information includes user's gender, age, schooling, marital status, duty
Industry, underlying diseases and the course of disease relevant to amnesia, risk factor, the inquiry result of family history.
As further improvement of the invention, touch screen is filled in for showing that tcm constitution recognizes scale interface for users,
Display shows the user's venous blood Hcy content acquired by blood-taking device by user's interrogation information of microphone inquiry acquisition
Information shows 8-iso-PGF 2a content information in the user's serum and urine of urine sampling device acquisition, and display bilateral hippocampus
NAA/Cr ratio information；The touch screen is also used to show user basic information input interface.
As further improvement of the invention, mild cognitive impairment diagnostic data processing unit is also used to obtain the body of user
Part information, and the electronic diagnostics archives of user are created or updated according to the identity information.
As further improvement of the invention, mild cognitive impairment diagnostic data processing unit is also used to asking according to user
Ask the printing diagnostic assessment report.
The present invention further protects a kind of mild cognitive impairment diagnostic data processing unit, the mild cognitive impairment diagnosis
Data processing equipment includes communication interface, the processor for being adapted for carrying out various program instructions and is suitable for storing a plurality of program instruction
Memory, described program instruction loaded by processor and execute following steps:
S1. the interrogation information of the user is obtained；
S2. it is scored according to the interrogation information, standards of grading include mini-mental state examination scale, Montreal cognition
Scale and daily living measuring scale are assessed, if mini-mental state examination scale score is at 24-27 points, Montreal is recognized
Know scale score 18-25 points of assessment, daily living measuring scale scores less than 16 points, then is judged as Patients with Mild Cognitive Impairment；
S3. the tcm constitution identification information of user's input is obtained；
S4. the constitution type in TCM that the user is judged according to the Constitution Identification information, if it is determined that deficiency of yang matter, phlegm wet
Matter or blood stasis matter, then further judge following information result；
S5. the limosis vein blood Hcy content and 8-iso-PGF 2a content information, urine 8-iso-PGF of the user are obtained
The NAA/Cr ratio information of 2a content information and bilateral hippocampus, if serum Hcy content is greater than 11 μm of ol/L, urine, blood 8-iso-
PGF2 α is greater than 40ng/L, and the NAA/Cr ratio of left and right hippocampus is 1.30 hereinafter, and meeting constitution type in TCM simultaneously is the deficiency of yang
Matter, phlegm wet matter or blood stasis matter, and meet S2, then it is judged as Patients with Mild Cognitive Impairment；
S6. the scoring of interrogation information, constitution type in TCM, limosis vein blood Hcy content and the 8-iso-PGF of the user are sent
2a content information, the NAA/Cr ratio information and judging result of urine 8-iso-PGF 2a content information and bilateral hippocampus and institute
State the network monitoring platform of mild cognitive impairment diagnostic data processing device network connection；
S7. the diagnostic assessment report for the user that network monitoring platform is sent is received
As further improvement of the invention, program instruction is also executed the following steps: by processor load and obtains user's
Identity information, and the electronic diagnostics archives of user are created or updated according to the identity information.
As further improvement of the invention, program instruction is also executed the following steps: by processor load according to user's
Request prints the diagnostic assessment report.
The invention has the following beneficial effects:
1. mild cognitive impairment diagnostic device of the present invention being capable of system, efficient, the safe and simple cognition feelings for judging user
Condition, for diagnosing mild cognitive impairment, play the role of to the treatment of user's early intervention it is very big, help user avoid developing into it is old
The cognitive disorders such as dementia disease；
2. apparatus of the present invention are easy to operate, judgement is accurate, are readily transported and store, cost is relatively low, it is easy to accomplish industrialization
Using.
Detailed description of the invention
Fig. 1 is the configuration diagram of mild cognitive impairment diagnostic device operation；
Fig. 2 is the structural schematic diagram of mild cognitive impairment diagnostic device；
Fig. 3 is the flow diagram of the data processing method in mild cognitive impairment diagnostic data processing unit of the present invention；
Wherein, 01, mild cognitive impairment diagnostic device；1, complete machine frame；11, work top；12, mainframe box；121,
Hand；13, bottom surface；131, pedestal；2, information collecting device；21, multi-voxel proton wave spectrum result input terminal；22, blood-taking device；23, it adopts
Urinate device；24, microphone；3, touch screen；4, mild cognitive impairment diagnostic data processing unit；41, communication interface；42, processing
Device；43, memory；5, test and analyze device；51, blood analysis device；52, urinalysis device；6, printer；61, paper
Outlet；02, network；03, network monitoring platform.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, the embodiment described is the embodiment of part of representative of the invention, rather than whole embodiments, this field are general
Other all embodiments obtained belong to protection of the invention to logical technical staff without making creative work
Range.
Purpose to realize the present invention, the present invention provides a kind of mild cognitive impairment diagnostic device, the mild cognitive impairments
Diagnostic device passes through microphone other than providing the tcm constitution identification scale of " Traditional Chinese Medicine Constitution Classification and judgement " standard for user
Acquisition obtain interrogation information, and by mild cognitive impairment diagnostic data processing unit according to mini-mental state examination scale,
Montreal Cognitive Assessment and daily living measuring scale carry out comprehensive score, mini-mental state examination scale score
At 24-27 points, Montreal Cognitive Assessment scores 18-25 points, and daily living measuring scale scores less than 16 points, then judges
For Patients with Mild Cognitive Impairment.Traditional interrogation are as follows: doctor is by understanding subjective symptom, the disease of patient with patient or insider
Situations such as disease occurs and evolution process, treatment experience, the method as diagnosis basis.The present apparatus is man-machine by touch screen and user
Interaction, in the form of user is according to own situation answer, judges the physical condition of user；It is man-machine mutually by microphone and user
It is dynamic, in the form of user is according to own situation oral answer, and according to scale score, judge the conditions of user.In addition, will
The blood and urine capture of user inputs the collection result of multi-voxel proton wave spectrum into device, according to the limosis vein blood of user
The NAA/Cr ratio of Hcy content and 8-iso-PGF 2a content information, urine 8-iso-PGF 2a content information and bilateral hippocampus
Information, if serum Hcy content is greater than 11 μm of ol/L, urine, blood 8-iso-PGF2 α are greater than 40ng/L, the NAA/Cr of left and right hippocampus
Ratio 1.30 hereinafter, and meeting constitution type in TCM simultaneously is deficiency of yang matter, phlegm wet matter or blood stasis matter, and meet mini-mental shape
State checks scale score at 24-27 points, and Montreal Cognitive Assessment scores 18-25 points, daily living measuring scale scoring
Less than 16 points, then it is judged as Patients with Mild Cognitive Impairment.
Shown in referring to Fig.1, Fig. 1 is the configuration diagram of mild cognitive impairment diagnostic device operation；Fig. 2 is mild cognitive barrier
Hinder the structural schematic diagram of diagnostic device.
In the present embodiment, the mild cognitive impairment diagnostic data processing unit 01 is flat by network 02 and network monitoring
Platform 03 connects.
In the present embodiment, the mild cognitive impairment diagnostic device 01 includes at least complete machine frame 1, information collecting device
2, touch screen 3, detection and analysis device 5 and mild cognitive impairment diagnostic data processing unit 4.The complete machine frame 1 is for holding
The information collecting device 2, touch screen 3 and mild cognitive impairment diagnostic data processing unit 4 are carried, the complete machine frame includes
There are pedestal 131 in work top 11, mainframe box 12, bottom surface 13, bottom surface.The information collecting device 2 includes at least more for inputting
Input terminal 21, blood-taking device 22, urine sampling device 23 and the microphone that interactive voice is carried out with doctor of traditional Chinese medicine of voxel wave spectrum result
24.The touch screen 3 is for realizing user's man-machine information interaction.The mild cognitive impairment diagnostic data processing unit 4 has
The calculating equipment of data sampling and processing and communication function including communication interface 41, is adapted for carrying out the processors of various program instructions
42 and the memory 43 suitable for storing a plurality of program instruction.
The information collecting device 2, test and analyze device 5 and microphone 24 with the mild cognitive impairment diagnostic data
Processing unit electrical connection can be filled by the communication interfaces such as USB interface, serial ports and mild cognitive impairment diagnostic data processing
4 electrical connections are set, the touch screen 3 can be electrically connected by video interface and the mild cognitive impairment diagnostic data processing unit 4
It connects.
Shown in referring to Figures 1 and 2, the information collecting device 2, including multi-voxel proton wave spectrum result input terminal 21, blood sampling dress
22, urine sampling device 23, microphone 24 and touch screen 3 is set to be set on the work top 11.Specifically, the information collection dress
2 location rights for being set to the table top are set, wherein multi-voxel proton wave spectrum result input terminal 21 is in 2 upper bit of information collecting device
It sets, blood-taking device 22 and urine sampling device 23 are in 2 lower left position of information collecting device, and wherein the left side is blood-taking device 22, and the right is
Urine sampling device 23, the microphone 24 are set to the bottom-right location of the information collecting device 2.The touch screen 3 is in workbench
11 left side of face, it is convenient for the user to operate.In other embodiments, the microphone 24 can increase video camera, and be integrated into one
Equipment.
The mild cognitive impairment diagnostic data processing unit 4 is set in the mainframe box 12, the mild cognitive barrier
Diagnostic data processing unit 4 is hindered to include communication interface 41, the processor 42 for being adapted for carrying out various program instructions and be suitable for storing
The memory 43 of a plurality of program instruction.The communication interface 41 is used for information collecting device 2, tests and analyzes device 5, microphone
24 and touch screen 3 be electrically connected with mild cognitive impairment diagnostic data processing unit 4.The processor 42 is for carrying out every program
Instruction, the memory 43 are used to store the testing result and diagnostic result of user.
The detection and analysis device 5 is set in the mainframe box 12, and the blood analysis device 51 including being located at left side is used
In the urinalysis device 52 of analysis serum Hcy content and 8-iso-PGF 2a content and right side, for analyzing urine 8-iso-
PGF 2a content.
As preferable embodiment, the mild cognitive impairment diagnostic device 01 further includes and the mild cognitive impairment
The printer 6 that diagnostic data processing unit 4 is electrically connected.The printer 6 is set to the inside of the mainframe box 12, and described
A groove is arranged in the side of mainframe box 12, as paper outlet 61.The printer 6 is by being removably fixed in the host
In case 12, printer 6 can be dismantled by opening mainframe box 12.Health evaluating report of the printer 6 for printing user, for
User understands the physical condition of oneself in time.
As preferred embodiment, the mild cognitive impairment diagnostic device 01 further includes being set to 12 side of mainframe box
Handle 121, the handle 121 is conveniently used for flexibly pushing the mild cognitive impairment diagnostic device 01.
As preferred embodiment, the mild cognitive impairment diagnostic device 01 further includes the pedestal being set on bottom surface 13
131, the pedestal 131 can avoid sliding in order to which the mild cognitive impairment diagnostic device 01 to be fixed on bottom surface.It is described
The quantity of pedestal 131 can be to be multiple, such as two or four.The pedestal 131 is vulcanie material, enhancing and ground
Frictional force.
Mild cognitive impairment diagnostic device of the present invention being capable of system, efficient, the safe and simple cognition feelings for judging user
Condition, for diagnosing mild cognitive impairment, play the role of to the treatment of user's early intervention it is very big, help user avoid developing into it is old
The cognitive disorders such as dementia disease.
Referring to shown in Fig. 3, Fig. 3 is the data processing method in mild cognitive impairment diagnostic data processing unit of the present invention
Flow diagram.In the present embodiment, the various steps of the data processing method are realized by computer software programs, should
Computer software programs are stored in computer readable storage medium (such as mild cognitive impairment in the form of computer program instructions
The memory 43 of diagnostic data processing unit 4) in, storage medium may include: read-only memory, random access memory, disk or
CD etc..In conjunction with Fig. 1, the processing unit of mild cognitive impairment diagnostic data described in the embodiment of the present invention 4 include communication interface 41,
The processor 42 and the memory 43 suitable for storing a plurality of program instruction for being adapted for carrying out various program instructions, described program instruction
It is loaded by processor 42 and executes following steps:
S1. the interrogation information of the user is obtained；
S2. it is scored according to the interrogation information, standards of grading include mini-mental state examination scale, Montreal cognition
Scale and daily living measuring scale are assessed, if mini-mental state examination scale score is at 24-27 points, Montreal is recognized
Know scale score 18-25 points of assessment, daily living measuring scale scores less than 16 points, then is judged as Patients with Mild Cognitive Impairment；
S3. the tcm constitution identification information of user's input is obtained；
S4. the constitution type in TCM that the user is judged according to the Constitution Identification information, if it is determined that deficiency of yang matter, phlegm wet
Matter or blood stasis matter, then further judge following information result；
Specifically, it is divided into according to by somatotypes: gentle type constitution, qi-deficiency type constitution, deficiency of Yin constitution, deficiency of yang type body
Matter, phlegm-damp type constitution, damp-heat type constitution, blood stasis type constitution, type of depression of QI constitution, special official report type constitution, diagnose according to tcm constitution and join
Carry out somatotypes judgement according to " Traditional Chinese Medicine Constitution Classification and judgement " standard that China Association of Traditional Chinese Medicine promulgates: gentle matter is conversion point
>=60 points, and other 8 kinds of equal < 40 of constitution conversion point divide；Biased >=40 points of constitution conversion point are "Yes", most with its biased constitution
High score determines.
S5. the limosis vein blood Hcy content and 8-iso-PGF 2a content information, urine 8-iso-PGF of the user are obtained
The NAA/Cr ratio information of 2a content information and bilateral hippocampus, if serum Hcy content is greater than 11 μm of ol/L, urine, blood 8-iso-
PGF2 α is greater than 40ng/L, and the NAA/Cr ratio of left and right hippocampus is 1.30 hereinafter, and meeting constitution type in TCM simultaneously is the deficiency of yang
Matter, phlegm wet matter or blood stasis matter, and meet S2, then it is judged as Patients with Mild Cognitive Impairment；
S6. the scoring of interrogation information, constitution type in TCM, limosis vein blood Hcy content and the 8-iso-PGF of the user are sent
2a content information, the NAA/Cr ratio information and judging result of urine 8-iso-PGF 2a content information and bilateral hippocampus and institute
State the network monitoring platform of mild cognitive impairment diagnostic data processing device network connection；
S7. the diagnostic assessment report for the user that network monitoring platform is sent is received.
For example, some user carries out illness detection using mild cognitive impairment diagnostic device 01, pass through touch screen 3, Mike
Wind 24 completes relevant human-computer interaction, has input testing result in the collection result input terminal 21 of multi-voxel proton wave spectrum, and will be empty
Abdomen blood and urine are respectively put into blood-taking device 22 and urine sampling device 23, are diagnosed to be that the results are shown in Table 1.
Table 1
Specifically, the diagnostic assessment report is automatically generated according to preset report template, the report template packet
Include user basic information column, this interrogation information bar, this tcm constitution result bar, this blood information column, this urine letter
Cease column, this hippocampus information bar, this diagnostic result column and doctor of traditional Chinese medicine's signature column.User basic information column is by user in base
The essential information that this information interface is filled in is shown according to information type；This interrogation information bar will be temporarily stored into memory 43
Interrogation result presentation come out, this tcm constitution result bar show tcm constitution information, this blood information column show blood
Hcy content and 8-iso-PGF2 alpha content result, this urine information bar show urine 8-iso-PGF2 alpha content result, this sea
Horse area information bar shows that the NAA/Cr ratio of left and right hippocampus, this diagnostic result column show the result of this diagnosis, if is light
Spend cognitive disorder patient.In other embodiments, after getting the identity information of user, interrogation data are just according to report template
The diagnostic assessment report for automatically generating the user, during user carries out interrogation, the processing of mild cognitive impairment diagnostic data
When device 4 gets the information of user, on the one hand the information is handled, it is on the other hand that corresponding information is (including original
Information and treated information) it is written into diagnostic assessment report, after the completion of user's interrogation, diagnostic assessment report will be automatic
It generates, saves the time, improve the Experience Degree of user.
Those skilled in the art is not under conditions of departing from the spirit and scope of the present invention that claims determine, also
Various modifications can be carried out to the above content.Therefore the scope of the present invention is not limited in above explanation, but by
The range of claims determines.
Claims (9)
1. a kind of mild cognitive impairment diagnostic device, including complete machine frame, information collecting device, detection and analysis device, touch screen
With mild cognitive impairment diagnostic data processing unit, which is characterized in that
The complete machine frame is examined for carrying the touch screen, detection and analysis device and information collecting device and mild cognitive impairment
Disconnected data processing equipment；
The information collecting device include for acquiring the blood-taking device of user's limosis vein blood, the dress for acquiring user's urine
Set, using 3.0T Siemens's superconducting magnetic resonance imaging system to user carry out multi-voxel proton wave spectrum collection result input terminal and
For carrying out the microphone of interactive voice with doctor of traditional Chinese medicine；
It is described to test and analyze the user's limosis vein blood progress Hcy content and 8-iso-PGF2a content point that device is used to acquire
It analyses and user's urine for that will acquire carries out 8-iso-PGF 2a content analysis；
The information collecting device, test and analyze device, microphone and touch screen with the mild cognitive impairment diagnostic data
Processing unit electrical connection；
The mild cognitive impairment diagnostic data processing unit is used to judge the user's according to the user information that touch screen acquires
Constitution type in TCM judges the serum Hcy content and 8-iso- of the user according to user's limosis vein blood that blood-taking device acquires
PGF 2a content results judge the urine 8-iso-PGF 2a content knot of the user according to user's urine that urine sampling device acquires
Fruit judges the bilateral hippocampus of the user according to the neuron mediator magnetic resonance pop metabolic information of user's bilateral hippocampus of input
NAA/Cr ratio as a result, receiving the interrogation for the user that microphone is sent as a result, and according to the tcm constitution class of the user
Type, serum Hcy content and 8-iso-PGF 2a content results, urine 8-iso-PGF 2a content results, bilateral hippocampus NAA/
Cr ratio result and interrogation result generate the diagnostic assessment report of the user.
2. a kind of mild cognitive impairment diagnostic device according to claim 1, which is characterized in that during the information type includes
Cure constitution information, interrogation information, limosis vein blood Hcy content and 8-iso-PGF 2a content information, urine 8-iso-PGF 2a
The NAA/Cr ratio information of content information, bilateral hippocampus.
3. a kind of mild cognitive impairment diagnostic device according to claim 2, which is characterized in that the interrogation information includes using
Family gender, age, schooling, marital status, occupation, underlying diseases and the course of disease relevant to amnesia, risk factor, family
The inquiry result of history.
4. a kind of mild cognitive impairment diagnostic device according to claim 1, which is characterized in that the touch screen is for showing
Tcm constitution identification scale interface for users is filled in, and user's interrogation information that display is acquired by microphone inquiry, display passes through
User's venous blood Hcy content information of blood-taking device acquisition shows 8-iso- in the user's serum and urine of urine sampling device acquisition
PGF 2a content information, and the NAA/Cr ratio information of display bilateral hippocampus；The touch screen is also used to show that user is basic
Data input interface.
5. a kind of mild cognitive impairment diagnostic device according to claim 1, which is characterized in that the mild cognitive impairment is examined
Disconnected data processing equipment is also used to obtain the identity information of user, and the electricity of user is created or updated according to the identity information
Son diagnosis archives.
6. a kind of mild cognitive impairment diagnostic device according to claim 1, which is characterized in that the mild cognitive impairment is examined
Disconnected data processing equipment is also used to print the diagnostic assessment report according to the request of user.
7. a kind of mild cognitive impairment diagnostic data processing unit, the mild cognitive impairment diagnostic data processing unit includes logical
Letter interface, the processor for being adapted for carrying out various program instructions and the memory suitable for storing a plurality of program instruction, feature exist
In described program instruction is loaded by processor and executes following steps:
S1. the interrogation information of the user is obtained；
S2. it is scored according to the interrogation information, standards of grading include mini-mental state examination scale, Montreal cognition assessment
Scale and daily living measuring scale, if mini-mental state examination scale score is at 24-27 points, Montreal cognition is commented
Estimate scale score 18-25 points, daily living measuring scale scores less than 16 points, then is judged as Patients with Mild Cognitive Impairment；
S3. the tcm constitution identification information of user's input is obtained；
S4. the constitution type in TCM of the user is judged according to the Constitution Identification information, if it is determined that deficiency of yang matter, phlegm wet matter or
Blood stasis matter then further judges following information result；
S5. the limosis vein blood Hcy content and 8-iso-PGF 2a content information, urine 8-iso-PGF 2a for obtaining the user contain
The NAA/Cr ratio information of information and bilateral hippocampus is measured, if serum Hcy content is greater than 11 μm of ol/L, urine, blood 8-iso-PGF2 α
Greater than 40ng/L, the NAA/Cr ratio of left and right hippocampus is 1.30 hereinafter, and meeting constitution type in TCM simultaneously is deficiency of yang matter, phlegm
Wet matter or blood stasis matter, and meet S2, then it is judged as Patients with Mild Cognitive Impairment；
S6. the scoring of interrogation information, constitution type in TCM, limosis vein blood Hcy content and the 8-iso-PGF 2a of the user are sent
Content information, the NAA/Cr ratio information of urine 8-iso-PGF 2a content information and bilateral hippocampus and judging result with it is described
The network monitoring platform of mild cognitive impairment diagnostic data processing device network connection；
S7. the diagnostic assessment report for the user that network monitoring platform is sent is received.
8. a kind of mild cognitive impairment diagnostic data processing unit according to claim 7, which is characterized in that described program refers to
Enable the identity information for being also executed the following steps: by processor load and obtaining user, and newly-built or more according to the identity information
The electronic diagnostics archives of new user.
9. a kind of mild cognitive impairment diagnostic data processing unit according to claim 7, which is characterized in that described program refers to
It enables being also executed the following steps: by processor load and the diagnostic assessment report is printed according to the request of user.
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