CN208476849U - A kind of portable POCT detector for multi-parameter - Google Patents
A kind of portable POCT detector for multi-parameter Download PDFInfo
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- CN208476849U CN208476849U CN201821080616.4U CN201821080616U CN208476849U CN 208476849 U CN208476849 U CN 208476849U CN 201821080616 U CN201821080616 U CN 201821080616U CN 208476849 U CN208476849 U CN 208476849U
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Abstract
The utility model discloses a kind of portable POCT detectors for multi-parameter, including shell, shell is equipped with sampling apparatus, sampling apparatus includes detection module and rotating module, rotating module includes fixing layer and the rotating layer that can rotate, fixing layer is located at the center of rotating layer, and fixing layer has a sample storage chamber of storage sample to be tested, rotating layer circumferentially multiple detection modules;When sampling, rotating layer rotation, detection module are corresponding with sample storage chamber position.The utility model can be not only used for the detection of multi-parameter and detection process is full-automatic, substantially increase detection efficiency.
Description
Technical field
The utility model relates to medical instruments fields, more specifically, it be related to it is a kind of for the portable of multi-parameter
POCT detector.
Background technique
In-vitro diagnosis, i.e. IVD (In Vitro Diagnosis), refer to except human body, by human sample (blood
Liquid, body fluid, tissue etc.) it is detected and obtains clinical diagnosis information, and then judge the products & services of disease or body function.
In-vitro diagnosis can be divided into central laboratory by utilization object again and use and Point-of-Care Test(POCT).POCT refers in disease
Clinical detection and the bedside detection (bedside testing) carried out beside people, is not necessarily clinical examination teacher usually to carry out.
It is to be analyzed at once in sampling location, saves complex process program of the sample in laboratory inspection, quickly obtains examining knot
A kind of new method of fruit.
Due to POCT be not necessarily to central laboratory, can directly be detected in victim, can quickly carry out diagnosis and treatment, nursing,
Course of disease observation, and then quality of medical care is improved, therefore permeability steps up in ICU, operation, emergency treatment, clinic and patient family.
The main purpose of POCT is exactly to obtain experimental result faster.The progress of diagnosis and ancillary technique, understanding to disease and is controlled
The raising for the treatment of level is the main reason for POCT is gradually concerned by people (pressure of financial aspects is secondary cause).These progress make
Some diseases diagnose other disease as early as possible and better healing close to eradicating.Easy to operate, being easy use is POCT
Another feature.POCT has become a part of diagnostic system by its ease for use;POCT assume responsibility for the function in laboratory but
It is not necessarily to traditional hospital laboratory equipment again.POCT can both be completed in the clinic of doctor or on the automobile started.POCT can
Not limited by time, place, 24 hours it is comprehensive for service for patients.
Traditional POCT detector such as blood glucose meter, uric acid instrument etc. is mostly the detection of single parameter and detection method is more multiple
It is miscellaneous.
Summary of the invention
The purpose of this utility model is to provide a kind of portable POCT detectors for multi-parameter, can be not only used for
The detection of multi-parameter and detection process is full-automatic, substantially increases detection efficiency.
The technical scheme adopted by the utility model to solve the technical problem is as follows: a kind of portable POCT for multi-parameter
Detector, it is characterised in that: including shell, shell is equipped with sampling apparatus, and sampling apparatus includes detection module and rotating module, turns
Dynamic model block includes fixing layer and the rotating layer that can rotate, and fixing layer is located at the center of rotating layer, and fixing layer, which has, to be stored
The sample storage chamber of sample to be tested, rotating layer circumferentially multiple detection modules;When sampling, rotating layer rotation, detection module with
Sample storage chamber position is corresponding.Preferably, rotating layer and fixing layer are plastics or metal material.
As a preferred option, rotating module further includes separating layer, and rotating layer is connected with fixing layer by separating layer.It is preferred that
, rotating layer, separating layer and fixing layer constitute driven wheel.Preferably, separating layer is bearing.Preferably, rotating layer and fixing layer
It is circle.
As a preferred option, detection module is equally spaced.
As a preferred option, shell is equipped with motor and driving wheel, driving wheel and motor axis connection, driving wheel and rotating layer
Engaged transmission.
As a preferred option, fixing layer is equipped with storage shell, driving motor and gear, and sample storage chamber is located at storage shell
In, driving motor output shaft is fixed with gear, gear and storage shell engaged transmission.
As a preferred option, detection module includes siphon layer, working electrode and auxiliary electrode, and siphon layer and rotating layer are solid
Fixed, working electrode and auxiliary electrode are respectively positioned on siphon layer.
As a preferred option, sample storage chamber has the opening of release sample to be tested, and siphon layer is equipped with siphon groove, siphon
Slot one end has interface, and interface extends to fixing layer, and when sampling, opening is aligned and contacts with interface.Preferably, siphon groove U
Type groove.Preferably, siphon rooved face is covered with hydrophilic film.Hydrophilic film can promote siphon groove siphon that sample to be tested is made to be evenly distributed, parent
Moisture film is cellulose and its derivates.
As a preferred option, auxiliary electrode is between working electrode and interface, one end of working electrode and auxiliary electrode
It is respectively positioned in siphon groove.Guarantee that sample to be tested is contacted with each electrode.
As a preferred option, detection module further includes reference electrode, and working electrode is located at reference electrode and auxiliary electrode
Between, one end of reference electrode, working electrode and auxiliary electrode is located in siphon groove.
As a preferred option, shell is equipped with electrode contacts module, and electrode contacts module includes working electrode contacts, auxiliary
Electrode contacts and reference electrode contact, when opening is aligned and contacts with interface, working electrode is connect with working electrode contacts, auxiliary
Electrode is connect with auxiliary electrode contact, and reference electrode is connect with reference electrode contact.Preferably, working electrode, auxiliary electrode and
Reference electrode is arranged in parallel, and is respectively positioned on the same side of siphon groove.It can reduce the occupied space of electrode pair positioned at the same side.It is excellent
Choosing, working electrode contacts, auxiliary electrode contact and reference electrode contact are metal clips.Auxiliary electrode is used for microcontroller list
Member detection kinetic current.
As a preferred option, sampling apparatus is detachably connected with shell.Sampling apparatus is set as disposable instrument
Removably is convenient for changing sampling apparatus.
As a preferred option, shell is equipped with electrode fixed seat, and fixing layer is equipped with electrode fixed seat jack, when installation,
Electrode fixed seat is inserted into electrode fixed seat jack.The cooperation of electrode fixed seat and electrode fixed seat jack is applied not only to work
The fixation of electrode, auxiliary electrode and reference electrode, and realize that the detachable installation of sampling apparatus and shell acts on.
As a preferred option, sample storage chamber has sample holes.Add sample to be tested when, syringe by sample holes to
Sample storage chamber injects sample to be tested.
As a preferred option, shell is additionally provided with processing display device, and processing display device includes micro-control unit, display
Screen, key and power supply.Micro-control unit handles sampled value and obtains testing result.Display screen is liquid crystal display, is used for quilt
Survey personnel's real time inspection testing result and detection time.Key includes key A and key B, and key A and key B are common plastics
Key.Many kinds of parameters, including detection parameters, detection time can be arranged in key, for example, 1. working electrode is glucose oxidation to number
Enzyme, then number 1. detection parameters be blood glucose, behind number and so on.
As a preferred option, working electrode surface has enzyme layer.Enzyme layer is different, and the parameter of detection is different, for example, enzyme layer
When for glucose oxidation enzyme, then detection parameters are blood glucose, and when enzyme layer is uricase, then detection parameters are uric acid.
As a preferred option, shell is equipped with charging jacks.
As a preferred option, power supply is powered to the detector.
The course of work of the utility model: by key-press input parameter, such as 1. working electrode is glucose oxidation enzyme to number, then
Number 1. detection parameters be blood glucose, behind number and so on, by sampling apparatus be inserted into shell in, will be to test sample by syringe
Originally it is injected into sample storage chamber, the siphon groove interface of micro-control unit controls number 1. is rotated to the opening with pattern detection chamber
Alignment, storage shell is driven to move down for gear until opening and interface contact, number each electrode 1. and corresponding electrode contacts
Contact, siphon layer carries out siphon, when micro-control unit detects the kinetic current of enzyme layer and sample to be tested on working electrode,
Sample to be tested absorption finishes, and micro-control unit controls gear driving storage shell moves up, micro-control unit controls driving wheel band
Dynamic rotating layer rotation makes sample storage chamber be located at number 1. and number between 2., meanwhile, micro-control unit carries out sample to be tested
Processing, processing result are shown by display screen, can inquire corresponding testing result by key A and B after detection.
Utility model has the advantages that 1, by setting rotating layer and fixing layer, multiple detections are set on rotating layer
Module can carry out the detection of multi-parameter;By driving wheel and rotating layer engaged transmission, detection process is full-automatic, substantially increases
Detection efficiency reduces the operation difficulty of user.
2, sampling apparatus and shell are detachably connected, and sampling apparatus is convenient for changing sampling apparatus as disposable instrument.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of 1 sampling apparatus of embodiment.
Fig. 2 is the sectional view of 1 sampling apparatus of embodiment.
Fig. 3 is the back view of shell.
Fig. 4 is the structural schematic diagram of detection module.
Fig. 5 is the front elevation of detector.
Fig. 6 is the structural schematic diagram of 2 sampling apparatus of embodiment.
Fig. 7 is the back view for implementing 2 shells.
Fig. 8 is the back view for implementing the setting of 2 case electrode contact modules full circle weeks.
It is identified in figure: shell 1, detection module 31, rotating module 32, rotating layer 321, fixing layer 322, separating layer 323, sample
This storage chamber 3222, storage shell 324, gear 325, siphon layer 311, working electrode 312, auxiliary electrode 313, reference electrode 314,
Opening 3223, electrode fixed seat 14, electrode fixed seat jack 3221, siphon groove 3111, interface 3112, working electrode contacts 11,
Auxiliary electrode contact 12, reference electrode contact 13, driving wheel 15, sample holes 16, charging jacks 17, display screen 2, key 3.
Specific embodiment
The present invention will be further described below with reference to the accompanying drawings and specific embodiments.
Sample to be tested and detection parameters
Sample to be tested is mostly physiological fluid, such as blood, urine, sweat, saliva, is felt wherein containing many clinical labororatories
The detection parameters of interest, such as glucose, cholesterol, glycosylated hemoglobin, blood ketone in blood, the uric acid in urine, sweat
In lactic acid etc..
Electrochemical analysis
Electrochemical analysis includes working electrode, reference electrode and auxiliary electrode.Reference electrode is used to pinpoint a zero point, electric current
It flows through working electrode and reference electrode constitutes a system that is obstructed or being powered less substantially, utilize the stability of reference electrode current potential
To measure the electrode potential of working electrode.Working electrode and auxiliary electrode constitute the system of an energization, for measuring work electricity
The electric current that pole passes through.Using three electrode measurement systems, come the point of research work electrode and the relationship of electric current simultaneously.
Circuit theory
Using single-chip microcontroller as micro-control unit, the sample to be tested in sample storage chamber is passed through by each electrode by siphon layer
It is connected in circuit, realizes that the reaction result to detection sample is adopted by source of stable pressure, across resistance operational amplifier circuit and 16 DAC
Sample, sampled value handle through single-chip microcontroller and obtain final data.
POCT detector
Embodiment 1
A kind of portable POCT detector for multi-parameter, as shown in Figure 1 and Figure 5, including shell 1, shell 1 are equipped with place
Display device is managed, processing display device includes micro-control unit, key 3, display screen 2 and power supply, and shell 1 is additionally provided with sampling cartridge
It sets, sampling apparatus includes detection module 31 and rotating module 32, and rotating module 32 includes rotating layer 321 and fixing layer 322, rotation
Layer 321 is hollow, and fixing layer 322 is located at the hollow position of rotating layer 321, and there is fixing layer 322 sample of storage sample to be tested to deposit
Put chamber 3222, the circumferentially multiple detection modules 31 of rotating layer 321;When sampling, the rotation of rotating layer 321, detection module 31 and sample
3222 position of this storage chamber is corresponding.Micro-control unit controls detection module 31 and rotating module 32.
As shown in Figure 1, detection module 31 is equally spaced.
As shown in Fig. 2, rotating layer 321 and fixing layer 322 are connected by separating layer 323, separating layer 323 is bearing.As
A kind of specific scheme, rotating layer 321, absciss layer 323 and fixing layer 322 are circle.Rotating layer 321, separating layer 323 and fixation
Layer 322 constitutes driven wheel.As a kind of specific scheme, rotating layer 321 and fixing layer 322 are metal material.
As shown in figure 3, shell 1 is equipped with motor and driving wheel 15, driving wheel 15 connect with motor output shaft, driving wheel 15 and
321 engaged transmission of rotating layer.
It is located at as shown in Fig. 2, sampling module is equipped with storage shell 324, driving motor and gear 325, sample storage chamber 3222
It stores in shell 324, driving motor output shaft and gear 325 are fixed, 324 engaged transmission of gear 325 and storage shell.Fixing layer 322
When with the sample storage chamber 3222 for storing sample to be tested, storage shell 324, driving motor and gear 325 are located at fixing layer 322
On.Driving motor drives gear 325 to rotate, so that the driving storage shell 324 of gear 325 moves up and down.
Sampling apparatus is detachably connected with shell 1.As shown in figures 1 and 3, shell 1 is equipped with electrode fixed seat 14, fixed
Layer 322 is equipped with electrode fixed seat jack 3221, is inserted into electrode fixed seat jack 3221 when installation, by electrode fixed seat 14.Electricity
Pole fixing seat 14 and the cooperation of electrode fixed seat jack 3221 are applied not only to working electrode 312, auxiliary electrode 313 and reference electrode
314 fixation, and realize that the detachable installation of sampling apparatus and shell 1 acts on.Sampling apparatus is as disposable instrument, setting
For removably, it is convenient for changing sampling apparatus.
As shown in Figure 1, sample storage chamber 3222 has sample holes 3224.Sample to be tested is added toward sample storage chamber 3222
When, syringe injects sample to be tested into sample storage chamber 3222 by sample holes 3224.
As shown in Figure 1 and Figure 4, detection module 31 includes siphon layer 311, working electrode 312 and auxiliary electrode 313.Such as Fig. 2
Shown, siphon layer 311 is located at 321 bottom end of rotating layer, and working electrode 312 and auxiliary electrode 313 are respectively positioned on siphon layer 311.Rainbow
It inhales layer 311 and is located at sample 3222 lower section of chamber to be measured.
As depicted in figs. 1 and 2, sample storage chamber 3222 has the opening 3223 of release sample to be tested, and siphon layer 311 is equipped with
Siphon groove 3111, siphon groove 3111 are U-type groove, and 3111 one end of siphon groove has interface 3112, and interface 3112 extends to fixing layer
322, when sampling, opening 3223 is aligned and contacts with interface 3112.3111 surface of siphon groove is covered with hydrophilic film.Hydrophilic film can promote
3111 siphon of siphon groove makes sample to be tested be evenly distributed, and hydrophilic film is cellulose and its derivates.
As shown in figure 4, auxiliary electrode 313, between working electrode 312 and interface 3112, working electrode 312 and auxiliary are electric
One end of pole 313 is respectively positioned in siphon groove 3111, guarantees that sample to be tested is contacted with each electrode.
As shown in figure 4, detection module 31 further includes reference electrode 314, working electrode 312 is located at auxiliary electrode 313 and ginseng
Than between electrode 314, one end of reference electrode 314 is located in siphon groove 3111.
As shown in figure 3, shell 1 is equipped with electrode contacts module, electrode contacts module includes working electrode contacts 11, auxiliary electricity
Pole contact 12 and reference electrode contact 13, opening 3223 is when being aligned and contact with interface 3112, the other end of working electrode 312 and
The connection of 11 one end of working electrode contacts, the other end of auxiliary electrode 313 are connect with 12 one end of auxiliary electrode contact, reference electrode
314 other end is connect with 13 one end of reference electrode contact, working electrode contacts 11, auxiliary electrode contact 12 and reference electrode touching
The other end of point 13 is connect with micro-control unit respectively.Working electrode 312, auxiliary electrode 313 are parallel with reference electrode 314 to be set
It sets, working electrode 312 is respectively positioned on the same side of siphon groove 3111 between reference electrode 314 and auxiliary electrode 313.Position
It can reduce the occupied space of electrode in the same side.Working electrode contacts 11, auxiliary electrode contact 12 and reference electrode touch at 13 points
It is metal clips.Auxiliary electrode 12 detects kinetic current for micro-control unit.
312 surface of working electrode has enzyme layer.Enzyme layer is different, and the parameter of detection is different, for example, enzyme layer is glucose oxidation enzyme
When, then detection parameters are blood glucose, and when enzyme layer is uricase, then detection parameters are uric acid.Key 3 and display screen 2 respectively with it is micro-
Control unit connection, as shown in figure 4, the display screen 2 is liquid crystal display.Display screen 2 is for showing testing result and time.
As shown in figure 4, it is common plastics key that key 3, which includes key A and key B, key A and key B,.Key 3 is used for
Detection parameters, detection time etc. are set, for example, 1. working electrode is glucose oxidation enzyme to number, then numbering 1. detection parameters is blood
Sugar, behind number and so on.
As shown in figure 4, shell 1 is equipped with charging jacks 17.Power supply is powered to entire detector.
In use, inputting parameter by key 3, such as 1. working electrode is glucose oxidation enzyme to number, then numbers 1. detection ginseng
Number be blood glucose, behind number and so on, by sampling apparatus be inserted into shell 1 in, sample to be tested is injected by sample by syringe
In this storage chamber 3222, the rotation of siphon groove interface 3112 of micro-control unit controls number 1. is opened to pattern detection chamber 3222
Mouthful alignment, storage shell 324 is driven to move down for gear 325 until opening 3223 is contacted with interface 3112, numbers each electrode 1.
It is contacted with corresponding electrode contacts, siphon layer 311 carries out siphon, when micro-control unit detects the enzyme layer on working electrode 312
When with the kinetic current of sample to be tested, sample to be tested absorption is finished, the driving of micro-control unit controls gear 325 storage shell 324 to
Upper movement, micro-control unit controls driving wheel 15 drive the rotation of rotating layer 321 that sample storage chamber 3222 is made to be located at number 1. and compile
Number 2. between, meanwhile, micro-control unit handles sample to be tested, and processing result is shown by display screen 2, after detection
Corresponding testing result can be inquired by key A and B.
Embodiment 2
Be in place of the present embodiment and the difference of embodiment 1: the rotating layer 321 in sampling apparatus has storage sample to be tested
Sample storage chamber 3222, the circumferentially multiple detection modules 31 of fixing layer 322, fixing layer 322 is hollow, and rotating layer 321 is located at
Hollow position, as shown in Figure 6.
As shown in fig. 7, shell 1 is equipped with electrode contacts module, electrode contacts module includes auxiliary electrode contact 12, work electricity
Pole contact 11 and reference electrode contact 13, electrode contacts module are circumferentially equally spaced, electrode contacts module and detection module 31
It corresponds.Alternatively, auxiliary electrode contact 13, working electrode contacts 11 and reference electrode contact 13 are laid with whole circumferential fashion,
Referring to Fig. 8.
As shown in fig. 6, shell 1 is equipped with motor, rotating layer 321 has the connecting hole 3211 of motor output shaft insertion, connection
Hole 3211 is connected with exporting axis.It is interference fitted between connecting hole 3211 and output shaft, when sampling apparatus is installed on shell 1,
Apply certain external force output shaft is inserted into connecting hole 3211.The interference fit of connecting hole 3211 and output shaft realizes sampling cartridge
Set the detachable installation effect with shell 1.When rotating layer 321 has the sample storage chamber 3222 of storage sample to be tested, shell is stored
324, driving motor and gear 325 are located on rotating layer 321.322 bottom end of fixing layer is equipped with mounting hole, and shell 1 is equipped with fixing axle.
When installation, fixing axle is inserted into mounting hole, to fix fixing layer 322.
In use, inputting parameter by key 3, such as 1. working electrode is glucose oxidation enzyme to number, then numbers 1. detection ginseng
Number be blood glucose, behind number and so on, by sampling apparatus be inserted into shell 1 in, sample to be tested is injected by sample by syringe
In this storage chamber 3222, micro-control unit controls rotating layer 321 makes the rotation of pattern detection chamber 3222 to pattern detection chamber 3222
It is open and is aligned with the siphon groove interface 3112 of number 1., gear drives storage shell 324 to move down until opening 3223 and interface
3112 contacts, each electrode numbered 1. are contacted with corresponding electrode contacts, and siphon layer 311 carries out siphon, when micro-control unit is examined
When measuring the kinetic current of the enzyme layer and sample to be tested on working electrode, sample to be tested absorption is finished, micro-control unit controls tooth
It takes turns 325 driving storage shells 324 to move up, the rotation of micro-control unit controls rotating layer 321 makes sample storage chamber 3222 be located at volume
Number 1. and number 2. between, meanwhile, micro-control unit handles sample to be tested, and processing result is shown by display screen, examines
Corresponding testing result can be inquired by key A and B after survey.
Content described in this specification embodiment is only an enumeration of the implementation forms of the utility model concept, this is practical new
The protection scope of type should not be construed as being limited to the specific forms stated in the embodiments, the protection scope of the utility model also and
In those skilled in the art according to the utility model design it is conceivable that equivalent technologies mean.
Claims (10)
1. a kind of portable POCT detector for multi-parameter, it is characterised in that: including shell, shell is equipped with sampling apparatus,
Sampling apparatus includes detection module and rotating module, and rotating module includes fixing layer and the rotating layer that can rotate, fixing layer position
In the center of rotating layer, fixing layer has the sample storage chamber of storage sample to be tested, rotating layer circumferentially multiple detections
Module;When sampling, rotating layer rotation, detection module are corresponding with sample storage chamber position.
2. a kind of portable POCT detector for multi-parameter as described in claim 1, it is characterised in that: rotating module is also
Including separating layer, rotating layer is connected with fixing layer by separating layer.
3. a kind of portable POCT detector for multi-parameter as described in claim 1, it is characterised in that: shell is equipped with electricity
Machine and driving wheel, driving wheel are connect with motor output shaft, driving wheel and rotating layer engaged transmission.
4. a kind of portable POCT detector for multi-parameter as described in claim 1, it is characterised in that: detection module etc.
Spacing arrangement.
5. a kind of portable POCT detector for multi-parameter as described in claim 1, it is characterised in that: detection module packet
Siphon layer, working electrode and auxiliary electrode are included, siphon layer is fixed with rotating layer, and working electrode and auxiliary electrode are respectively positioned on siphon layer
On.
6. a kind of portable POCT detector for multi-parameter as claimed in claim 5, it is characterised in that: sample storage chamber
Opening with release sample to be tested, siphon layer are equipped with siphon groove, and siphon groove one end has interface, and interface extends to fixing layer,
When sampling, opening is aligned and contacts with interface.
7. a kind of portable POCT detector for multi-parameter as claimed in claim 6, it is characterised in that: detection module is also
Including reference electrode, one end of working electrode, reference electrode and auxiliary electrode is respectively positioned in siphon groove.
8. a kind of portable POCT detector for multi-parameter as claimed in claim 7, it is characterised in that: shell is equipped with electricity
Pole contact modules, electrode contacts module include working electrode contacts, auxiliary electrode contact and reference electrode contact, opening and interface
When being aligned and contacting, working electrode is connect with working electrode contacts, and auxiliary electrode is connect with auxiliary electrode contact, reference electrode with
The connection of reference electrode contact.
9. a kind of portable POCT detector for multi-parameter as described in claim 1, it is characterised in that: shell is equipped with
Electrode fixed seat, fixing layer are equipped with the electrode fixed seat jack for being inserted into electrode fixed seat.
10. a kind of portable POCT detector for multi-parameter as described in claim 1, it is characterised in that: sample storage
Chamber has sample holes;Shell is additionally provided with processing display device, and processing display device includes micro-control unit, display screen, key, electricity
Source and charging jacks.
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CN108593731A (en) * | 2018-07-09 | 2018-09-28 | 浙江大学山东工业技术研究院 | A kind of portable POCT detectors for multi-parameter |
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CN108593731A (en) * | 2018-07-09 | 2018-09-28 | 浙江大学山东工业技术研究院 | A kind of portable POCT detectors for multi-parameter |
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