The fungal drug sensitive check-out console
Technical field
The utility model relates to a kind of fungal drug sensitive check-out console.
Background technology
Mycosis is that people often run in daily life, comprises tinea, tinea unguium, pulmonary mycosis, stomach mycosis, otomycosis etc.And moniliosis and cryptococcosis are modal two kinds of mycosises.Moniliosis mainly is acute, the subacute or chronic infection that Candida albicans causes, often invades skin, mucous membrane, also can cause internal organ or systemic infection.Clinical symptom is intricate, anxious slow differing.When the monilial infection symptom appearred in patient, medical personnel are many can to use miconazole, nystatin, clotrimazole, miconazole, and econazole, medicines such as butoconazole are patient.Cryptococcosis can be invaded humans and animals, is generally exogenous infection, also may be autogenous infection, and for human, normally condition is pathogenic for it.Cryptococcus neoformans can be sent out to whole body when the human body lower immune function, mainly invades central nervous system, and meningitis, encephalitis, cerebral granuloma etc. take place, and can invade bone, muscle, lymphoglandula, mucocutaneous chronic inflammatory diseases and the abscess of causing in addition.The widely used medicine of medical personnel has potassiumiodide, sodium iodide, garlic essence, amphotericin B etc.
Antibacterials have played important effect to mycotic control, but owing to not science, the blindness of medication process are abused antibacterials, thereby caused a lot of pathogenic funguses to produce resistance.In recent years along with the application of heavy dose of microbiotic, hormone, immunosuppressor, and the carrying out of transplant operation, antibacterials not only cause drug waste to mycotic control effect worse and worse, but also have incured loss through delay patient's the state of an illness.At present, the application of antibiotic drug is very extensive, and various pathogenic bacterias are to the susceptibility difference of antibiotic medicine, and the different strains of bacterium of the same race is also variant to the susceptibility of same medicine.Whether can accurately hold the dosage of antibacterials and pathogenic bacteria to the relation between the susceptibility of antibacterials, just become and quick and precisely treat mycotic key.At present the fungal drug sensitive check-out console that generally adopts is single certain medicine to be tested, and has limited the property rapidly and efficiently of whole process thus to a great extent, and influence is to effective control of pathophoresis with to the good treatment of disease.
The utility model content
Technical problem to be solved in the utility model is to overcome the deficiencies in the prior art, provide a kind of efficiently, fungal drug sensitive check-out console efficiently.
The technical scheme that the utility model adopted is: the utility model comprises antibiotics susceptibility test plate body, plate lid, described plate lid and described antibiotics susceptibility test plate body closely cooperate, described antibiotics susceptibility test plate body is provided with at least one row's test hole, each row all can be provided with several described test holes on request, is coated with encrusting substance in the described test hole; One end of described antibiotics susceptibility test plate body also can be provided with one or more medicine bottle putting holes as required, be used to place and just using or standby antibiotic drug medicine bottle, the other medicine that is provided with of described test hole indicates symbol, be used for indicating the classification that each test hole is wanted testing drug, handled easily, minimizing error.
Also include feminine gender, positive control hole on the described antibiotics susceptibility test plate body, in described negative control hole, add a certain amount of pollution-free fungal drug sensitive nutrient solution, in test, be used to carry out blank; Described positive control hole is self positive control hole; The number of described test hole is provided with as required, and can be divided into many rows, every row's the different antibiotic drug of described test hole endoperidium, two rows or arrange the test hole bag by the antibiotic drug of the same race of different concns more; Prepare bacteria suspension, a certain amount of described bacteria suspension is sneaked in the described fungal drug sensitive nutrient solution, and make described bacteria suspension uniform distribution in described fungal drug sensitive nutrient solution; Described bacteria suspension one by one is added in all the other described test holes with a certain amount of; Place the fungal drug sensitive nutrient solution of described interpolation bacteria suspension 35~37 ℃ environment to cultivate, see its look become with record sensitivity, in result such as quick, resistance, measured result is significant to clinical treatment and medication; Experience and antibiotic drug kind commonly used according to susceptibility detects can described test hole optimization be set to two rows, and seven test holes of every row carry out fungal drug sensitive simultaneously to seven kinds of different antibiotic drugs commonly used and detect.
The beneficial effects of the utility model are: the utility model is provided with some test holes, can be simultaneously carry out fungal drug sensitive to multiple antibiotic drug and detect, and makes detections, selects medicine, treatment is faster efficiently; The utility model is provided with the medicine bottle putting hole at an end of antibiotics susceptibility test plate body, is used to place just using or standby antibiotic drug medicine bottle, brings convenience to operating process; The other medicine that is provided with of test hole of the present utility model indicates symbol, as-,+, all kinds of antibiotic drug code names etc., indicate the antibiotic drug classification in each test hole thus, make things convenient for the staff to operate, prevent to produce error because of obscuring.
Description of drawings
Fig. 1 is the utility model antibiotics susceptibility test plate main body structure synoptic diagram;
Fig. 2 is an A-A sectional view shown in Figure 1;
Fig. 3 is the structural representation of the utility model plate lid.
Embodiment
As Fig. 1, Fig. 2, shown in Figure 3, the utility model comprises antibiotics susceptibility test plate body 1, plate lid 2, described plate lid 2 closely cooperates with described antibiotics susceptibility test plate body 1, described antibiotics susceptibility test plate body 1 is provided with test hole 3, be coated with encrusting substance in the described test hole 3, described test hole 3 can be divided into plurality of rows as required, and every row can be provided with several described test holes 3 on request, in the present embodiment, described test hole 3 is set to two rows, seven test holes of every row, wherein a row is the lower concentration test hole, another row is height degree test hole.Comprising amphotericin B (AMB) test hole 31, nystatin (NYS) test hole 32, econazole (ECO) test hole 33, miconazole (MIC) test hole 34, KETOKONAZOL (KET) test hole 35, fluconazole (FLU) test hole 36, itraconazole (ITR) test hole 37; One end of described antibiotics susceptibility test plate body 1 also can be provided with one or more medicine bottle putting holes 5 as required, present embodiment is provided with a medicine bottle putting hole, be used to place and just using or standby antibiotic drug medicine bottle, described negative control hole A1, described positive control hole B1, the described test hole 3 other medicines that are provided with indicate symbol 4, are used for indicating the classification of each test hole antibiotic drug.
When the professional operated, described negative control hole A1 inoculated described fungal drug sensitive nutrient solution, was used to carry out blank in test; B1 is self positive control hole.Prepare bacteria suspension, this bacteria suspension must use after preparation immediately.Draw 100 μ L bacteria suspensions and sneak into described fungal drug sensitive nutrient solution, shake up; Continue and respectively add 150 μ L bacteria suspensions in all the other described test holes with sample injector; Add 1-2 to each described test hole and drip sterile mineral oil, make it not infected with good each test hole of capping.Place 35~37 ℃ to cultivate observations after 12~24 hours the described fungal drug sensitive nutrient solution that is added with bacteria suspension; When described B1 positive control hole becomes tawny, can report the antibiotics susceptibility test result, according to described test hole change in color, judge that respectively relative medicine is: responsive, in quick, resistance, its corresponding symbol is: "--", "+-", " ++ ", wherein '-' number represents that described test hole still is purple, color and the solid colour of described positive control hole B1, the i.e. tawny of the described test hole of '+' expression.For example, for described amphotericin B (AMB), the back result is after tested: showing purple during A is capable, show purple during B is capable, then is responsive; If A shows purple in capable, show tawny during B is capable, quick in then being; If be shown as tawny during A is capable, be shown as tawny during B is capable, then be resistance; All the other described antibiotic drugs: the test result of nystatin (NYS), econazole (ECO), miconazole (MIC), KETOKONAZOL (KET), fluconazole (FLU), itraconazole (ITR) all can judge by above-mentioned way.Measured result is significant to clinical treatment and medication.