CN201814576U - Magnetic resonance olfaction stimulator - Google Patents
Magnetic resonance olfaction stimulator Download PDFInfo
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- CN201814576U CN201814576U CN2010205162391U CN201020516239U CN201814576U CN 201814576 U CN201814576 U CN 201814576U CN 2010205162391 U CN2010205162391 U CN 2010205162391U CN 201020516239 U CN201020516239 U CN 201020516239U CN 201814576 U CN201814576 U CN 201814576U
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Abstract
The utility model relates to medical detection equipment, in particular to a magnetic resonance olfaction stimulator which solves the problems of inaccurate olfaction stimulation exertion and control time, longer olfactory odor stimulation time and olfaction adaptability generation in the current olfactory function magnetic resonance imaging inspection. The technical scheme is as follows: the stimulator comprises an oil-free air pressure pump used for generating airflow, an air humidification bottle with an inlet connected to an outlet of the oil-free air pressure pump through a pipe, an air flow regulating valve with an inlet connected to an outlet of the air humidification bottle through a pipe, a multichannel switching mechanism with an inlet connected to an outlet of the air flow regulating valve through a pipe, an electric controller connected to all the electric control ends of the multichannel switching mechanism, odour source containers with the inlets connected to the outlets of all the channels through pipes, odour sources installed in all the odour source containers, a unifying pipe connected to the outlets of all the odour source containers, and an odour release pipe connected to the outlet of the unifying pipe. The olfaction stimulator is used for conducting short-time repeated olfaction stimulation in the olfactory magnetic resonance imaging inspection, and is accurate in time control.
Description
Technical field:
This utility model relates to the medical science checkout equipment, specifically is a kind of auxiliary facilities " magnetic resonance olfactory stimulation device " that is used for the olfactory sensation magnetic resonant imaging examination.This olfactory stimulation device is by the multichannel switching mechanism of electronic circuit (or computer program) control, accurately control the odor source gas in the different passage odor source containers, discharge and termination at different time and interval, and olfactory stimulation is accurately repeated at short notice, occur activating the olfactory adaptation phenomenon that lowers thereby eliminate olfactory cortex, make the subjects under accurate olfactory stimulation, carry out olfactory sensation magnetic resonant imaging examination accurately.
Background technology
Magnetic resonance functional imaging (functional MRI, fMRI) nineteen ninety is at first found by the people such as Ogawa of AT﹠T Labs, it is (to be BloodOxygen Level Dependent according to the local behaviour area of brain blood oxygen level, BOLD) variation judges which brain domain has participated in corresponding neural activity.When brain is handled certain task, neuron metabolism in the functional areas increases, local function district blood is for increasing, cause white (diamagnetism) content of Oxygenated blood red eggs in the inner blood of functional areas to increase relatively, and deoxyhemoglobin (paramagnetism) content reduces relatively, the variation of blood oxygen level shows as the signal enhancing in specific magnetic resonance in these functional areas, can judge that thus those brain districts have participated in corresponding activity.Therefore, fMRI provides excellent means for the research of medical science, physiology, psychology and even Cognitive Science.The fMRI development of China is later, and reported first in 1996 is just carried out rapidly thereafter like the mushrooms after rain.Present domestic fMRI research is primarily aimed at functions such as motion, audition, vision, language, the research report of rare olfactory function imaging.The difficulty of olfactory function fMRI mainly is present in the inspection method and the equipment of olfactory function imaging, vision, audition, tactile stimulation at present all had commercial stimulator device to sell, and domestic only several routine olfactory sensation fMRI inspections all adopt suitable simple and crude equipment condition to carry out, giving with time control of its olfactory stimulation is also accurate inadequately, and the time that smell stimulates is grown (about 30 seconds).Discover to give olfactory stimulation after 20 seconds, attenuating just can appear activating in olfactory cortex, i.e. olfactory sensation produces the olfactory adaptation effect.So olfactory stimulation must repeat to give at short notice, therefore, accurately, multiple magnetic resonance in short-term is to guarantee that the olfactory function imaging inspection is crucial accurately and reliably with the olfactory stimulation device.
The utility model content:
Control inaccuracy in order to solve present magnetic resonance with the existing time of olfactory stimulation device, the problem that the time that stimulates is long, this utility model development also discloses a kind of magnetic resonance olfactory stimulation device, it is by the multichannel switching mechanism of electronic circuit (or computer program) control, accurately control the odor source gas in the different channel container, at different time, interval discharges and ends, and olfactory stimulation is accurately repeated at short notice, occur activating the olfactory adaptation phenomenon that lowers thereby eliminate olfactory cortex, make the subjects can be accurately, carry out olfactory sensation magnetic resonant imaging examination accurately under the olfactory stimulation of science.Its technical scheme includes: odor source; The container that holds odor source; Odor source container liberation port; Design in the control valve of odor source container liberation port; It is characterized in that: it is by the oil-free air compressor pump that produces air-flow; Inlet is connected in the air saturation bottle of oil-free air compressor pump compressed air outlet through pipeline; Inlet is connected in the air flow rate adjustment valve of air saturation bottle outlet through pipeline; Inlet is connected in the multichannel switching mechanism of air flow rate adjustment valve outlet through pipeline; Be connected in each electric control end in the multichannel switching mechanism, control the electric controller that each channel air is led to, ended; Be connected in the odor source container of each air duct outlet through pipeline with inlet; Be loaded on the odor source in each odor source container; Be connected in the normalizing pipe of each odor source container outlet; The abnormal smells from the patient that is connected in the outlet of normalizing pipe discharges pipeline and constitutes.
Above-mentioned oil-free air compressor pump, air saturation bottle, air flow rate adjustment valve, multichannel switching mechanism, electric controller each several part are arranged at magnetic resonance operation room Inner; In odor source container, normalizing pipe and abnormal smells from the patient releasing tube each several part are arranged between magnetic resonance imaging; Two parts are connected by multichannel Teflon material pipe-line system.
Its air saturation bottle is adorned the diplopore bottle stopper by the wide-mouth bottle stopper of water-filling, and constitutes as entry and exit in diplopore plug glaze pipe.
Above-mentioned air flow rate adjustment valve adopts commercially available nothing oil, tasteless manual air flow rate adjustment valve, flow 6～8L/min.
First kind of formation scheme of above-mentioned multichannel switching mechanism is: connect a plurality of commercially available electromagnetic valves by the outlet of single inlet, multiple exit pipe and constitute, the electric control end of each electromagnetic valve is connected in electric controller by selector switch.
Above-mentioned electric controller is made of by the electric control end that selector switch is connected in each electromagnetic valve the time-delay relay of civil power through rectification, manostat power supply.
Second kind of formation scheme of above-mentioned multichannel switching mechanism is: adopt computer program to constitute as each electric control end of the commercially available single inlet of electric controller control, multiple exit transfer valve.
Above-mentioned electric controller constitutes for the defeated program control pulse signal of computer programming that is connected to each electric control end of above-mentioned transfer valve of gating switch, driver in commercially available single inlet, multiple exit transfer valve.
Above-mentioned each odor source container by glass container plug dress diplopore pipe close as go into, export mixes, the odor source of the identical or different kind of packing or concentration in glass container during detection.
Above-mentioned odor source liberation port is for being adhesively fixed in the abnormal smells from the patient releasing tube road junction of below, subjects nostril.
Advantage and good effect:
A. originally novel multichannel switching mechanism by electronic circuit (or computer program) control, accurately the odor source gas in the different passage odor source containers of control discharges and termination at different time, interval, smell was discharged with the time of ending be accurate to the submicrosecond level, shorten the time of olfactory stimulation, avoided olfactory center the situation of olfactory adaptation to occur.
B. the big flow oil-free air of this novel employing compressor pump and no mask designs, when electromagnetic valve is opened, can guarantee under the fast subjects of reaching of the pure odor source abnormal smells from the patient nostril, during closed electromagnetic valve, rapidly existing abnormal smells from the patient is dispelled again, thus the accurately stimulation of control smell in the short as far as possible time.
Continuous parts such as the oil-free air compressor pump in C. originally novel, air saturation bottle, air flow rate adjustment valve, multichannel switching mechanism, electric controller are arranged at the magnetic resonance equipment operation room, both be convenient to operation control, and the ferromagnetism article in the stimulator also can not influence the carrying out of magnetic resonance imaging; Hold in the container of odor source and odor source then be arranged between magnetic resonance imaging, make odor source as far as possible near the subjects, when needing abnormal smells from the patient to discharge, open valve, abnormal smells from the patient can arrive subjects, valve-off rapidly, can rapidly existing abnormal smells from the patient be dispelled, odorlessness is residual.
D. this novel employing multi-channel pipeline system and the design of many group odor sources; Both can use identical abnormal smells from the patient and concentration, and the odor source that constantly more renews when using, the stable of odorousness guaranteed; Also can use different abnormal smells from the patients or concentration, thereby carry out multiple abnormal smells from the patient or concentration is checked flexibly.
E. these novel parts divide two parts setting, and two parts connect by multichannel Teflon material pipe-line system has avoided the residual and union dyeing of abnormal smells from the patient in pipe-line system.
F. this novel air saturation bottle that connects behind the oil-free air compressor pump carries out humidifying to gas, has alleviated the drying stimulation of air to subjects's nasal cavity.
Description of drawings:
Fig. 1 is this novel magnetic resonance olfactory stimulation device theory diagram;
Fig. 2 is first kind of formation scheme of this novel multichannel switching mechanism: connect a plurality of commercially available electromagnetic valves by the outlet of single inlet, multiple exit pipe and constitute, the electric control end of each electromagnetic valve connects by civil power through rectification, the time-delay relay of manostat power supply, the electric controller block diagram that selector switch constitutes;
Fig. 3 is second kind of formation scheme of this novel multi-channel switching mechanism: adopt list inlet, the multiple exit transfer valve that computer program is controlled commercially available single inlet, multiple exit transfer valve electric control end reaches with gating switch, driver, electromagnetic valve constitute to be connected block diagram.
The explanation of main label among each figure:
1.-oil-free air compressor pump 2.-air saturation bottle
3.-air flow rate adjustment valve 4.-multichannel switching mechanism
The single inlet of 4 ' .-, multiple exit transfer valve 5.-electric controller
6.-Teflon material pipe-line system 7.-odor source container, odor source
8.-normalizing pipe 9.-abnormal smells from the patient discharges pipeline
10.-subjects or patient MC.-computer
The F.-electromagnetic valve
The specific embodiment:
In order to further specify content of the present utility model, technical scheme, feature, lift following example and accompanying drawings again in following: as Figure 1-3, the technical solution of the utility model includes: the oil-free air compressor pump 1 that produces air-flow; Inlet is connected in the air saturation bottle 2 of oil-free air compressor pump compressed air outlet through pipeline; Inlet is connected in the air flow rate adjustment valve 3 of air saturation bottle outlet through pipeline; Inlet is connected in the multichannel switching mechanism 4 of air flow rate adjustment valve outlet through pipeline; Be connected in each electric control end in the multichannel switching mechanism, control the electric controller 5 that each channel air is led to, ended; Be connected in the odor source container 7 of each air duct outlet through pipeline with inlet; Be loaded on the odor source 7 in each odor source container; Be connected in the normalizing pipe 8 of each odor source container outlet; Inlet is connected in the outlet of normalizing pipe, and its pipe outlet is fixed in abnormal smells from the patient release pipeline 9 formations of below, nostril.
Above-mentioned oil-free air compressor pump 1, air saturation bottle 2, air flow rate adjustment valve 3, multichannel switching mechanism 4, electric controller 5 each several parts are arranged at magnetic resonance operation room Inner; In odor source container, odor source 7, normalizing pipe and abnormal smells from the patient release pipeline 9 etc. partly are arranged between magnetic resonance imaging; Two parts are connected by multichannel Teflon material pipe-line system 6.
Its air saturation bottle 2 constitutes as entry and exit by the wide mouthed bottle bottle plug dress diplopore bottle stopper of water-filling and in diplopore plug glaze pipe.
Above-mentioned air flow rate adjustment valve 3 adopts commercially available nothing oil, tasteless manual air flow rate adjustment valve, its flow 6～8L/min.
First kind of formation scheme of above-mentioned multichannel switching mechanism 4 is: connect a plurality of commercially available electromagnetic valve F by the outlet of single inlet, multiple exit pipe and constitute, the electric control end of each electromagnetic valve is connected in electric controller 5 by selector switch.
Above-mentioned electric controller 5 is made of by the electric control end that selector switch is connected in each electromagnetic valve the time-delay relay of civil power through rectification, manostat power supply.
Second kind of formation scheme of above-mentioned multichannel switching mechanism 4 is: adopt computer program as the commercially available single inlet of electric controller 5 controls, multiple exit transfer valve 4 ' the electric control end constitute.
Above-mentioned electric controller 5 for through commercially available single inlet, multiple exit transfer valve 4 ' in the defeated computer MC that is connected to each electric control end of transfer valve of gating switch, the driver program control pulse signal of programming constitute.
Above-mentioned each odor source container 7 by glass container plug dress diplopore pipe close as go into, export mixes, the odor source of the identical or different kind of packing or concentration in glass container during detection.
Above-mentioned odor source liberation port is for being adhesively fixed in the abnormal smells from the patient releasing tube road junction of below, subjects 10 nostrils.
Claims (10)
1. a magnetic resonance olfactory stimulation device includes: odor source; The container that holds odor source; Odor source container liberation port; Design in the control valve of odor source container liberation port; It is characterized in that: it is by the oil-free air compressor pump that produces air-flow; Inlet is connected in the air saturation bottle of oil-free air compressor pump compressed air outlet through pipeline; Inlet is connected in the air flow rate adjustment valve of air saturation bottle outlet through pipeline; Inlet is connected in the multichannel switching mechanism of air flow rate adjustment valve outlet through pipeline; Be connected in each electric control end in the multichannel switching mechanism, control the electric controller that each channel air is led to, ended; Be connected in the odor source container of each air duct outlet through pipeline with inlet; Be loaded on the odor source in each odor source container; Be connected in the normalizing pipe of each odor source container outlet; The abnormal smells from the patient that is connected in the outlet of normalizing pipe discharges pipeline and constitutes.
2. magnetic resonance olfactory stimulation device according to claim 1 is characterized in that: above-mentioned oil-free air compressor pump, air saturation bottle, air flow rate adjustment valve, multichannel switching mechanism, electric controller each several part are arranged at magnetic resonance operation room Inner; In odor source container, normalizing pipe and abnormal smells from the patient releasing tube each several part are arranged between magnetic resonance imaging; Two parts are connected by multichannel Teflon material pipe-line system.
3. magnetic resonance olfactory stimulation device according to claim 1 is characterized in that: its air saturation bottle constitutes as entry and exit by water-filling wide-mouth bottle stopper dress diplopore bottle stopper and in diplopore glaze pipe.
4. magnetic resonance olfactory stimulation device according to claim 1 is characterized in that: above-mentioned air flow rate adjustment valve adopts commercially available nothing oil, tasteless manual air flow rate adjustment valve, flow 6～8L/min.
5. magnetic resonance olfactory stimulation device according to claim 1, it is characterized in that: first kind of formation scheme of above-mentioned multichannel switching mechanism is: connect a plurality of commercially available electromagnetic valves by the outlet of single inlet, multiple exit pipe and constitute, the electric control end of each electromagnetic valve is connected in electric controller by selector switch.
6. magnetic resonance olfactory stimulation device according to claim 5 is characterized in that: above-mentioned electric controller is made of by the electric control end that selector switch is connected in each electromagnetic valve the time-delay relay of civil power through rectification, manostat power supply.
7. magnetic resonance olfactory stimulation device according to claim 1 is characterized in that: second kind of formation scheme of above-mentioned multichannel switching mechanism is: adopt computer program to constitute as each electric control end of the commercially available single inlet of electric controller control, multiple exit transfer valve.
8. magnetic resonance olfactory stimulation device according to claim 7 is characterized in that: above-mentioned electric controller constitutes for the defeated program control pulse signal of computer programming that is connected to each electric control end of above-mentioned transfer valve of gating switch, driver in commercially available single inlet, multiple exit transfer valve.
9. magnetic resonance olfactory stimulation device according to claim 1 is characterized in that: above-mentioned each odor source container by glass container plug dress diplopore pipe close as go into, export mixes, the odor source of the identical or different kind of packing or concentration in glass container during detection.
10. magnetic resonance olfactory stimulation device according to claim 1 is characterized in that: above-mentioned odor source liberation port is for being adhesively fixed in the abnormal smells from the patient releasing tube road junction of below, subjects nostril.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010205162391U CN201814576U (en) | 2010-09-03 | 2010-09-03 | Magnetic resonance olfaction stimulator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010205162391U CN201814576U (en) | 2010-09-03 | 2010-09-03 | Magnetic resonance olfaction stimulator |
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| CN201814576U true CN201814576U (en) | 2011-05-04 |
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| CN2010205162391U Expired - Fee Related CN201814576U (en) | 2010-09-03 | 2010-09-03 | Magnetic resonance olfaction stimulator |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379687A (en) * | 2011-11-25 | 2012-03-21 | 天津赛特思科贸有限公司 | Odor conduction smell test instrument and control method thereof |
| CN103454335A (en) * | 2013-09-09 | 2013-12-18 | 华东理工大学 | Multichannel integrated olfactory analog instrument and on-line analysis method for biological fermentation process |
| CN107583167A (en) * | 2017-10-09 | 2018-01-16 | 郭怡辰 | People is with smell instrument for training |
| CN107765200A (en) * | 2017-11-20 | 2018-03-06 | 中国科学技术大学 | A kind of liquid delivery device based on magnetic resonance detection |
| TWI663401B (en) * | 2017-03-02 | 2019-06-21 | 日商企鵝系統有限公司 | Olfactory inspection device, olfactory inspection method and medium |
| CN112946106A (en) * | 2021-01-26 | 2021-06-11 | 中国科学院西双版纳热带植物园 | Low-disturbance building block type odor stimulation modulator |
| CN114160021A (en) * | 2021-12-03 | 2022-03-11 | 深圳先进技术研究院 | Gas release control device for experiments |
| CN116616720A (en) * | 2023-07-21 | 2023-08-22 | 心灵秀(苏州)科技有限公司 | Smell transmission smell detection equipment and control method thereof |
-
2010
- 2010-09-03 CN CN2010205162391U patent/CN201814576U/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379687A (en) * | 2011-11-25 | 2012-03-21 | 天津赛特思科贸有限公司 | Odor conduction smell test instrument and control method thereof |
| CN103454335A (en) * | 2013-09-09 | 2013-12-18 | 华东理工大学 | Multichannel integrated olfactory analog instrument and on-line analysis method for biological fermentation process |
| CN103454335B (en) * | 2013-09-09 | 2015-11-11 | 华东理工大学 | A kind of integrated olfactory analog instrument of hyperchannel and biological fermentation process on-line analysis |
| TWI663401B (en) * | 2017-03-02 | 2019-06-21 | 日商企鵝系統有限公司 | Olfactory inspection device, olfactory inspection method and medium |
| CN107583167A (en) * | 2017-10-09 | 2018-01-16 | 郭怡辰 | People is with smell instrument for training |
| CN107583167B (en) * | 2017-10-09 | 2024-02-13 | 郭怡辰 | Olfactory training instrument for human |
| CN107765200A (en) * | 2017-11-20 | 2018-03-06 | 中国科学技术大学 | A kind of liquid delivery device based on magnetic resonance detection |
| CN112946106A (en) * | 2021-01-26 | 2021-06-11 | 中国科学院西双版纳热带植物园 | Low-disturbance building block type odor stimulation modulator |
| CN114160021A (en) * | 2021-12-03 | 2022-03-11 | 深圳先进技术研究院 | Gas release control device for experiments |
| CN116616720A (en) * | 2023-07-21 | 2023-08-22 | 心灵秀(苏州)科技有限公司 | Smell transmission smell detection equipment and control method thereof |
| CN116616720B (en) * | 2023-07-21 | 2023-09-12 | 心灵秀(苏州)科技有限公司 | Smell transmission smell detection equipment and control method thereof |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110504 Termination date: 20130903 |