CN104248476B - A kind of simple and easy Novel experimental anesthetic machine - Google Patents
A kind of simple and easy Novel experimental anesthetic machine Download PDFInfo
- Publication number
- CN104248476B CN104248476B CN201410534309.9A CN201410534309A CN104248476B CN 104248476 B CN104248476 B CN 104248476B CN 201410534309 A CN201410534309 A CN 201410534309A CN 104248476 B CN104248476 B CN 104248476B
- Authority
- CN
- China
- Prior art keywords
- centrifuge tube
- gas flowmeter
- anesthetic
- tube
- connects
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of simple and easy Novel experimental anesthetic machine, including oxygen increasing pump, also include the centrifuge tube being provided with liquid anaesthetic agent, oxygen increasing pump connects with the first gas flowmeter and the second gas flowmeter respectively, first gas flowmeter is connected with centrifuge tube by centrifuge tube air induction conduit, second gas flowmeter connects with threeway, and threeway is connected with centrifuge tube by centrifuge tube outtake tube, and threeway connects with induction of anesthesia box or breathing anesthesia box also by anesthetic tube。The plurality of advantages such as the present invention has structural strength height, Stability Analysis of Structures, safe and reliable, concentration is easily-controllable, inexpensive。
Description
Technical field
The present invention relates to animal experiment device field, be more particularly to a kind of simple and easy Novel experimental anesthetic machine, it is adaptable to the anesthesia of meiofauna。
Background technology
The operation principle of zoopery anesthetic gas machine is to introduce the stream in anesthesia bottle by mechanical circuit, and then promote anesthetis to volatilize, the air-flow carrying anesthetic gases imports to animal nasal cavity, whole body is arrived everywhere through the respiratory system of animal and blood circulation after, thus central nervous system being made directly inhibitory action, produce the effect of general anesthesia。Anesthetic gas machine belongs to semi open model equipment, can be classified as several part according to its operation principle: air supply system, anesthetis volatilization system, induction of anesthesia and maintenance system, residual gas scavenging system etc.。
The anesthetic machine sold on market is used for field of medicaments, and owing to be applied to human body, design is general relatively accurate, and structure is complicated, relatively costly accordingly。Even if the anesthetic machine being applied to zooscopy is also relatively costly, not easily promote practicality。But, along with biological development, animal application in biological experiment is more and more extensive, therefore, and easy, quick, safety and the anesthetic machine of effective anesthetized animal can also become a problem demanding prompt solution。Existing Medical anesthetic machine and commercial animal anesthetic machine, the cost of its costliness brings unnecessary waste。Some laboratory design anesthetic machine of oneself, but effect is poor, and residual gas is revealed more serious, the health of experimenter is unfavorable。In consideration of it, applicant devises this Simple And Practical type anesthetic machine for laboratory animal, its design is simple, efficient, and structure is simplified, easy and simple to handle, it is possible to the such as minitype animal experiment such as rat, mice is effectively anaesthetized。This anesthetic machine is with low cost, and reliability is high, and concentration is adjustable, easy to carry, can be widely applied to biology laboratory。
Furthermore, it is contemplated that the health of experimenter, specially with the addition of residual gas when design and eliminate system, it is possible to prevent residual gas from entering laboratory, and then experimenter is effectively protected。
Summary of the invention
It is an object of the invention to be in that for the problems referred to above that prior art exists, it is provided that a kind of simple and easy Novel experimental anesthetic machine, reduce operation easier, reduce the cost of Animal Anesthesia, and have residual gas elimination system。
The above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of simple and easy Novel experimental anesthetic machine, including oxygen increasing pump, also include the centrifuge tube being provided with liquid anaesthetic agent, oxygen increasing pump connects with the first gas flowmeter and the second gas flowmeter respectively, first gas flowmeter is connected with centrifuge tube by centrifuge tube air induction conduit, second gas flowmeter connects with threeway, and threeway is connected with centrifuge tube by centrifuge tube outtake tube, and threeway connects with induction of anesthesia box also by anesthetic tube。
Induction of anesthesia box as above is transparent sealing plastic lunch box。
A kind of simple and easy Novel experimental anesthetic machine, also includes the breathing anesthesia box connected with anesthetic tube, breathes and offer pneumostome on anesthesia box。
A kind of simple and easy Novel experimental anesthetic machine, also includes vacuum pump, and vacuum pump connects with breathing anesthesia box。
Centrifuge tube air induction conduit as above extends to below the liquid level of liquid anaesthetic agent, and described centrifuge tube outtake tube extends to the ullage of liquid anaesthetic agent。
The present invention compared with prior art, has the advantage that
1, the design of small-sized anesthetic machine is simple, easy to operate and be easy to carry about with one。In development process, cast out heavy high-pressure nitrogen bottle and high-pressure oxygen cylinder etc., simply used small-sized oxygen increasing pump and can realize air-flow supply。Any experimenter can correctly operate after simple study。This equipment dependability is high, can promote the use of。
2, anesthetis concentration easily regulates, and the concentration of anesthetic gases is to be mixed generation according to a certain percentage by anesthetic gases and air。Therefore, the air-flow monitoring of this small-sized anesthetic machine is coordinated control by two gas flowmeters (the first gas flowmeter and the second gas flowmeter) and is completed, and then effectively regulates anesthetis concentration in gas, thus effectively controlling toy depth of anesthesia。This anesthetic machine is controlled gas flow by mass air flow sensor, simply efficiently, saves medicine。Animal both can have been carried out rapid induction anesthesia (<1min) by this anesthetic machine, it is also possible to maintains low anesthetis concentration and makes the long-time (>2h of animal) keep narcotism。
3, tail gas is led outdoor by available vacuum pump, it is to avoid it spills in laboratory, and then reaches the purpose of Protection personnel。
4, selected equipment cost is low, and total price, far below business machine on market, should be generalized in biotic experiment。It addition, all systems are all inside a cuboid acrylic board case, it is simple to carry and use；Adjusting knob is respectively mounted on the outer wall, is beneficial to adjustment。
The present invention has These characteristics, has realized the purpose that cost is low, structure is simple, operation is easy, efficiency is high, is by zooperal ideal equipment。
Accompanying drawing explanation
Fig. 1 is the structural representation of the first embodiment of the present invention。
Fig. 2 is the structural representation of the second embodiment of the present invention。
In figure: 1-anesthetic machine shell；2-oxygen increasing pump；3-the first gas flowmeter；4-the second gas flowmeter；5-anesthetis；6-centrifuge tube (can be selected for 50ml centrifuge tube)；7-centrifuge tube air inlet；8-centrifuge tube gas outlet；9-threeway；10-induction of anesthesia box；11-breathes anesthesia box；12-vacuum pump；13-flat board。
Detailed description of the invention
Below in conjunction with accompanying drawing, technical scheme is described in further detail。
Embodiment 1
As shown in Figure 1 and 2,
One, air-flow supply:
The air-flow supply of the present invention is both from oxygen increasing pump 2。Oxygen increasing pump 2 has two outlets, and one of them outlet imports the first gas flowmeter 3(250mL/min by conduit), regulate flow velocity, the air draught of certain flow rate can be produced, this air-flow pipe air induction conduit by centrifugation imports centrifuge tube 6, can produce anesthetic gases；Another outlet is then connected to the second gas flowmeter 4(1L/min by conduit), regulate flow velocity, the air draught of certain flow rate can be produced, mix with the anesthetic gases finally produced by centrifuge tube gas outlet 8, and then anesthesia gas concentration can be diluted。This place uses the gas flowmeter of two kinds of flow velocitys, and wherein gas flow rate can comparatively be finely tuned by the first gas flowmeter 3 easily, consequently facilitating effectively control the generation concentration of anesthetic gases；The introducing of the second gas flowmeter 4, then after providing enough oxygen for toy, plays the effect quickly reducing anesthesia gas concentration。Anesthetic machine shell 1 can be selected for cuboid acrylic board case, oxygen increasing pump the 2, first gas flowmeter the 3, second gas flowmeter 4, centrifuge tube 6, centrifuge tube air inlet 7 are arranged in anesthetic machine shell 1, the adjusting knob of the first gas flowmeter 3 and the second gas flowmeter 4 is arranged on anesthetic machine shell 1, and the mouth of pipe of centrifuge tube 6 stretches out anesthetic machine shell 1。
Two, induction of anesthesia:
Induction of anesthesia box 10 can be selected for common transparent sealing plastic lunch box, is possible not only to observe easily the narcotism of animal, and is very easy to obtain。Induction of anesthesia box 10 not only induces box cheaply a lot of than commercialization, and easily finds the succedaneum of various volume size, thus being applicable to the animal of different building shape。In use procedure, open an osculum in side and top。
Being poured into 50ml centrifuge tube from top by liquid anaesthetic agent (such as isoflurane, halothane), lid of screwing on seals gas。For the ease of adding liquid anaesthetic agent at any time, not affecting formation and the release of anesthetic gases, centrifuge tube 6 has to pass through simple reformation simultaneously, namely establishes two and catheter outer diameter aperture of the same size newly in centrifuge tube 6 side, one of them is centrifuge tube air inlet, and another one is centrifuge tube gas outlet。Wherein, centrifuge tube air inlet is directly connected to the gas outlet of the first gas flowmeter 3 by centrifuge tube air induction conduit。For the ease of producing the anesthetic gases of high concentration, the outlet of the centrifuge tube air induction conduit in centrifuge tube 6 has to extend into the bottom of centrifuge tube 6 or directly contacts bottom centrifuge tube；And the air flow inlet place of the centrifuge tube outtake tube of centrifuge tube outlet must on the liquid level of liquid anaesthetic agent。Meanwhile, the junction of centrifuge tube air induction conduit, centrifuge tube outtake tube and centrifuge tube needs to seal with glass cement。The anesthetic gases produced is by admixed together by threeway 9 with the air that the second gas flowmeter 4 is derived, and mixing gas is introduced directly into induction of anesthesia box by anesthetic tube。
Opening oxygen increasing pump 2, regulating the uninterrupted of the first gas flowmeter 3 and the second gas flowmeter 4, thus controlling narcotic concentration。Induce in anaesthesia process animal, need to use the anesthetic gases of high concentration, tune up by the flow velocity of the first gas flowmeter 3, produce the initial anesthetic gas of higher concentration, the flow velocity of the second gas flowmeter 4 is reduced as far as possible simultaneously, and then produce a small amount of air diluting anesthetic gases, thus producing high concentration anesthetic gases。Reduce the concentration of anesthetic gases if necessary, then need reverse operating, namely reduce the flow velocity of the first gas flowmeter 3, improve the flow velocity of the second gas flowmeter 4。
Export through centrifuge tube gas outlet 8 after anesthetis volatilization, and the T-shaped interface point of threeway is transported by conduit, mix with by the air of the second gas flowmeter 4 input, then arrive induction of anesthesia box toy is carried out induced anesthesia (test be respectively less than 1min with the anesthesia duration of rat and mice)。
Three, anesthesia maintenance
After Animal Anesthesia, transfer on flat board 13, box is anaesthetized in breathing and connects with anesthetic tube, animal mouth and nose are placed in the breathing anesthesia mouth place breathing anesthesia box, maintain narcotism；
Regulate the ratio of the first gas flowmeter 3 and the second gas flowmeter 4, reduce anesthetis concentration, efficiently maintain Animal Anesthesia state (test can more than 2h with the continuous narcosis time of rat and mice) thus long-term；
For Protective strategy personnel, residual gas is discharged outside laboratory through pipeline by vacuum pump 12 sucking-off。
During use, if anesthetis total amount is too low, then closes oxygen increasing pump 2, turn on centrifuge tube 6, add anesthetis, screw a lid on, be again turned on for controlling oxygen increasing pump 2 and the power supply of vacuum pump 12。Convenient and easy, and do not affect whole system。Close anesthetic machine by closing power supply。
Specific embodiment described herein is only to present invention spirit explanation for example。Described specific embodiment can be made various amendment or supplements or adopt similar mode to substitute by those skilled in the art, but without departing from the spirit of the present invention or surmount the scope that appended claims is defined。
Claims (1)
1. a simple and easy Novel experimental anesthetic machine, including oxygen increasing pump (2), it is characterized in that, also include the centrifuge tube (6) being provided with liquid anaesthetic agent, oxygen increasing pump (2) connects with the first gas flowmeter (3) and the second gas flowmeter (4) respectively, first gas flowmeter (3) is connected with centrifuge tube (6) by centrifuge tube air induction conduit, second gas flowmeter (4) connects with threeway (9), threeway (9) is connected with centrifuge tube (6) by centrifuge tube outtake tube, threeway connects with induction of anesthesia box (10) also by anesthetic tube；
Induction of anesthesia box (10) is transparent sealing plastic lunch box；
Also include breathing anesthesia box (11) connected with anesthetic tube, breathe and anesthesia box (11) offers pneumostome；
Also including vacuum pump (12), vacuum pump (12) connects with breathing anesthesia box (11)；
Described centrifuge tube air induction conduit extends to below the liquid level of liquid anaesthetic agent, and described centrifuge tube outtake tube extends to the ullage of liquid anaesthetic agent。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410534309.9A CN104248476B (en) | 2014-10-10 | 2014-10-10 | A kind of simple and easy Novel experimental anesthetic machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410534309.9A CN104248476B (en) | 2014-10-10 | 2014-10-10 | A kind of simple and easy Novel experimental anesthetic machine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104248476A CN104248476A (en) | 2014-12-31 |
| CN104248476B true CN104248476B (en) | 2016-06-22 |
Family
ID=52183960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410534309.9A Active CN104248476B (en) | 2014-10-10 | 2014-10-10 | A kind of simple and easy Novel experimental anesthetic machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104248476B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107595428A (en) * | 2017-10-19 | 2018-01-19 | 孙红阳 | A kind of experimental animal breathing anesthesia outfit and its application method |
| CN108742942A (en) * | 2018-06-19 | 2018-11-06 | 中国科学院电子学研究所 | General anesthesia neuromechanism studies acute experiment platform and chronic experiment platform |
| CN112891014B (en) * | 2021-01-18 | 2022-05-06 | 辽宁中医药大学 | Suction-type anaesthesia device for experimental animals |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201171730Y (en) * | 2008-03-11 | 2008-12-31 | 上海睿智化学研究有限公司 | Gas anesthesia device |
| CN101953720A (en) * | 2010-11-01 | 2011-01-26 | 同济大学 | Small-sized insect anesthesia apparatus |
| CN102138834A (en) * | 2011-03-01 | 2011-08-03 | 西安交通大学医学院第一附属医院 | Anesthesia device for animal experiment |
| CN102743238A (en) * | 2012-07-02 | 2012-10-24 | 温州医学院附属第二医院 | Method for managing experimental animal respiration |
| CN203506929U (en) * | 2013-10-16 | 2014-04-02 | 中国人民解放军第二军医大学 | Simple respirator of naked mole rat |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7560076B2 (en) * | 2004-08-18 | 2009-07-14 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| JP2009011505A (en) * | 2007-07-03 | 2009-01-22 | Sumika Technoservice Kk | Simple inhalation anesthesia device and multistage type simple inhalation anesthesia apparatus equipped with the same |
-
2014
- 2014-10-10 CN CN201410534309.9A patent/CN104248476B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201171730Y (en) * | 2008-03-11 | 2008-12-31 | 上海睿智化学研究有限公司 | Gas anesthesia device |
| CN101953720A (en) * | 2010-11-01 | 2011-01-26 | 同济大学 | Small-sized insect anesthesia apparatus |
| CN102138834A (en) * | 2011-03-01 | 2011-08-03 | 西安交通大学医学院第一附属医院 | Anesthesia device for animal experiment |
| CN102743238A (en) * | 2012-07-02 | 2012-10-24 | 温州医学院附属第二医院 | Method for managing experimental animal respiration |
| CN203506929U (en) * | 2013-10-16 | 2014-04-02 | 中国人民解放军第二军医大学 | Simple respirator of naked mole rat |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104248476A (en) | 2014-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203874239U (en) | Breathing machine atomizing device with adjustable flow speed | |
| CN201356881Y (en) | Circulation closed anesthetic machine | |
| CN104248476B (en) | A kind of simple and easy Novel experimental anesthetic machine | |
| CN104001253A (en) | Invasive/noninvasive mechanical ventilation gas humidifying and heating system and method | |
| CN105944201B (en) | A kind of medicinal intelligent ventilator | |
| CN202590119U (en) | Breathing machine atomization device | |
| CN208481525U (en) | A kind of meiofauna inhalation anaesthesia apparatus | |
| CN203710499U (en) | Pneumatic respirator special for infants | |
| CN205698790U (en) | A kind of medical ventilator | |
| CN107174712A (en) | A kind of breathing equipment by control of breathing | |
| CN203954409U (en) | A kind of with/without wound mechanical ventilation gas humidifying heating system | |
| CN104096302B (en) | The combination inhalation device of the antibacterial humidification Based Intelligent Control of portable constant temperature | |
| CN204699187U (en) | Digitized composite-crossing anesthesia in operating room toxic emission monitoring system | |
| CN203634614U (en) | Controllable air passage humidifying device | |
| CN206138234U (en) | Anesthesia system is breathed to toy | |
| CN206063514U (en) | A kind of medicinal intelligent lung ventilator | |
| CN205598364U (en) | Oxygen drive air flue atomizing humidifier | |
| CN205031696U (en) | Internal medicine respirator | |
| CN203989325U (en) | Medical vaporizer | |
| CN201840744U (en) | Multi-purpose ventilation-anesthetization breathing device | |
| CN207152866U (en) | Multi-functional valve of speaking | |
| CN204932523U (en) | Simple oxygen respiratory mask under a kind of rabbit autonomous respiration anesthesia | |
| CN214970602U (en) | Emergency anesthesia device for respiratory tract burn | |
| CN110841163A (en) | Breathe internal medicine nursing with oxygen therapy device | |
| CN204395166U (en) | A kind of hot and humid area device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |