CN107595428A - A kind of experimental animal breathing anesthesia outfit and its application method - Google Patents

A kind of experimental animal breathing anesthesia outfit and its application method Download PDF

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Publication number
CN107595428A
CN107595428A CN201710976932.3A CN201710976932A CN107595428A CN 107595428 A CN107595428 A CN 107595428A CN 201710976932 A CN201710976932 A CN 201710976932A CN 107595428 A CN107595428 A CN 107595428A
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China
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anesthesia
bearing plate
outer cover
experimental animal
breathing
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CN201710976932.3A
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Chinese (zh)
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孙红阳
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Individual
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Abstract

The invention discloses a kind of experimental animal breathing anesthesia outfit, including outer cover, anaesthetize chamber, air inlet pipe and muffler, and anesthesia source of the gas, pressure sensitive device is provided with the inside of outer cover, the pressure sensitive device includes bearing plate, spring, rheostat and controller, one end of the spring is fixed on outer cover inwall, the other end is connected with bearing plate, bearing plate bottom surface connects rheostat, rheostat is connected with controller, the front port connection air inlet pipe of the outer cover, rear port is provided with the rear end cap of threaded connection or snapping, the rear end cap is connected with inlet shroud, the edge of inlet shroud is sleeved on the inner side of the rear end cap.The breathing anesthesia outfit of the present invention, anesthetic gases is evenly distributed in anesthesia intracavitary, reach optimal most fast anaesthetic effect, anesthesia is judged according to the motion state of animal, stop anesthesia in time, reduce the injury for sucking excessive anaesthetic to animal, and present apparatus good airproof performance, reduce harm of the anesthetic to experimenter.

Description

A kind of experimental animal breathing anesthesia outfit and its application method
Technical field
The present invention relates to one kind breathing anesthesia outfit and its application method, and in particular to a kind of experimental animal is anaesthetized with breathing Device and its application method.Belong to experimental animal engineering device technique field.
Background technology
The anesthesia of experimental animal is experiment, a link of efficiency evaluation inside medical R&D process traditional Chinese medicine. China's toy clinical practice general anesthesia is mainly two methods of inhalation anesthesia and non-inhalation anesthesia at present.Suction fiber crops in recent years It is liquor-saturated to rely on the advantages that its is safe and stable, controllability is strong, adverse reaction is few, increasingly consequence is clinically occupied, it is existing The gradually trend of substitution non-inhalation anesthesia.Too small yet with small hamster individual, the volatile anesthetic such as ether/isoflurane does not have Specialize in the filling cotton such as the anaesthesia apparatus used, generally use beaker, specimen jar and make simple anaesthesia apparatus by oneself, but the big of anesthetic of volatilizing Amount volatilization, impacts to operator's health, also wastes anesthetic;And anaesthesia dosage and depth of anesthesia are not easy to grasp control; Volatile anesthetic has the characteristics of quick-anaesthesia rapid recovery again, when animal is taken out during operating cost, easily delays the anesthetic stage time. Existing part is directed to the anesthesia tools of animal, although being provided with air inlet pipe and muffler, the gas of air inlet pipe is most directly to be entered Enter muffler, cause anesthesia gas concentration on the inside of outer cover not high, anesthesia efficiency is low, and is also easy to produce cross-infection.In addition, existing fiber crops Liquor-saturated device can not react Animal Anesthesia situation, so that animal can be caused to suck excessive anaesthetic and cause dead or wound Evil, may influence further experiment.
The content of the invention
The purpose of the present invention is to overcome above-mentioned the deficiencies in the prior art, there is provided a kind of experimental animal breathing anesthesia outfit And its application method.
To achieve the above object, the present invention uses following technical proposals:
A kind of experimental animal breathing anesthesia outfit, including outer cover, anaesthetize chamber, air inlet pipe and muffler, and anesthesia gas Source, is provided with pressure sensitive device on the inside of outer cover, and the pressure sensitive device includes bearing plate, spring, rheostat and control Device, one end of the spring are fixed on outer cover inwall, and the other end is connected with bearing plate, bearing plate bottom surface connection rheostat, Rheostat is connected with controller, the front port of outer cover connection air inlet pipe, and rear port is provided with threaded connection or snapping Rear end cap, the rear end cap are connected with inlet shroud, and the edge of the inlet shroud is sleeved on the inner side of the rear end cap.
As one of preferable technical scheme, the end of the air inlet pipe is provided with one-way vent valve.
As one of preferable technical scheme, connection cloth is sealed between bearing plate and the outer cover inwall.
As one of preferable technical scheme, the outer cover front portion is provided with return-air chamber, and return-air cavity wall is uniformly distributed along the circumference Stomata is provided with, stomata is communicated in anesthesia chamber and return-air chamber;Return-air cavity outer wall is provided with gas returning port, gas returning port and the muffler Connection.
As one of further preferred technical scheme, the gas returning port is arranged at the top of outer cover with muffler.
As one of preferable technical scheme, the inlet shroud is made up of elastomeric material, and the middle part of the inlet shroud is set There is entrance.
It is provided with as one of preferable technical scheme, in the inlet shroud positioned at inlet ambient and easily tears seam.
As one of preferable technical scheme, the outer cover is that insulating materials is made with bearing plate.
As one of preferable technical scheme, display, hand switch and automatic switch are provided with the controller.
A kind of experimental animal application method of breathing anesthesia outfit, comprises the following steps:
(1) entrance of the experimental animal through device is put into breathing anesthesia outfit, turns on the power and connect anesthesia source of the gas, if Put and manually or automatically control, anesthetic gases enters anesthesia chamber by air inlet pipe, and enters return-air chamber through stomata, and last cooled via return air pipe enters Enter retracting device;
(2) bearing plate up and down that experimental animal is struggled or motion is touched in device, causes to extrude to upper lower spring, extruding production Raw pressure shown on the controller by rheostat, the pressure value on display with animal continuous motion without It is disconnected to change;
(3) being continually fed into anesthetic gases, the depth of anesthesia of animal gradually increase, and the movement range of animal gradually subtracts Small, until holonarcosis, animal stop motion, now, the gravity of animal are concentrated on lower bearing plate, upper bearing plate pressure is Zero, i.e., when showing that upper bearing plate pressure is zero on display, when lower bearing plate pressure value is stable, according to the setting of step (1) Stop anesthesia manually or control stopping anesthesia automatically by controller.
Beneficial effects of the present invention:A kind of experimental animal provided by the invention breathing anesthesia outfit, simple in construction, design Rationally, the anesthesia of animal can be judged using pressure inductor according to the reactiveness of animal, turns off anesthesia gas in time Source, reduce the injury for sucking excessive anaesthetic to animal.Utilize return-air chamber and equally distributed multiple stomatas, it can be ensured that Anesthetic gases is evenly distributed on anesthesia intracavitary, reaches optimal most fast anaesthetic effect.The anti-stop of one-way vent valve of air inlet pipe end The gas of thing exhalation enters air inlet pipe, can avoid cross-infection.Present apparatus sealing is strong, avoids experimenter's inhalation anesthesia Agent, reduce harm of the anesthetic to experimenter, its present apparatus application method is simple, and the work for alleviating experimenter is born Load.
Brief description of the drawings
Fig. 1 is the structural representation of one embodiment of the invention;
Fig. 2 is cross-sectional view;
Description of reference numerals:1- outer covers;2- anaesthetizes chamber;3- air inlet pipe;4- mufflers;5- bearing plates;6- springs;7- variable resistances Device;8- controllers;9- one-way vent valves;10- connection cloth;11- return-air chambers;12- stomatas;13- gas returning ports;14- rear ports;15- Inlet shroud;16- entrances;17- easily tears seam;18- rear end caps;19- displays;20- automatic/hands switch.
Embodiment
The present invention will be further elaborated with reference to the accompanying drawings and examples, it should which explanation, the description below is only It is to explain the present invention, its content is not defined.
As shown in Fig. 1 Fig. 2, the experimental animal of the embodiment of the present invention is included with breathing anesthesia outfit, including outer cover 1, anesthesia Chamber 2, air inlet pipe 3 and muffler 4, and anesthesia source of the gas, the inner side of outer cover 1 is provided with pressure sensitive device, pressure sensitive device Including bearing plate 5, spring 6, rheostat 7 and controller 8, outer cover 1 is that insulating materials is made with bearing plate 5.Bearing plate 5, bullet Spring 6 and rheostat 7 include upper and lower bearing plate, upper lower spring and upper and lower rheostat.One end of spring 6 is fixed on the inwall of outer cover 1 On, the other end is connected with bearing plate 5, and the bottom surface of bearing plate 5 connection rheostat 7, rheostat 7 is connected with controller 8, controller 8 It is connected with anesthesia compressed air source unit, controller 8 can cut off anesthesia source of the gas in time, stop fiber crops according to the anesthesia of experiment mice It is liquor-saturated.
The end of air inlet pipe 3 is provided with one-way vent valve 9, and anesthetic gases enters anesthesia chamber 2 by one-way vent valve 9 In, the gas anaesthetized in chamber 2 cannot be introduced into air inlet pipe, avoid cross-infection.
In order to prevent gas leakage, connection cloth 10 is sealed between bearing plate 5 and the inwall of outer cover 1.
In order to reach more preferable gas distribution effect evenly, the gas prevented from air inlet pipe 3 is directly entered the quilt of muffler 4 Drain, the front portion of outer cover 1 is provided with return-air chamber 11, and the inwall of return-air chamber 11, which is uniformly distributed along the circumference, is provided with stomata 12, and stomata 12 is communicated in Anesthesia chamber 2 and return-air chamber 11, the outer wall of return-air chamber 11 are provided with gas returning port 13, and gas returning port 13 connects with muffler 4.Due to anaesthetizing gas Body easily converges in anesthesia chamber 2 bottom, therefore gas returning port 13 and muffler 4 are arranged at into outer cover 1 than the gas weight that animal breathes out Top, this design can make anesthetic gases anesthesia intracavitary extended residence time, improve anesthesia efficiency.
In order to prevent the rear port 14 of outer cover 1 poorly sealed, rear port 14 is provided with inlet shroud 15, inlet shroud 15 is bullet Property material, the middle part of inlet shroud 15 is provided with entrance 16, is provided with inlet shroud 15 around entrance 16 and easily tears seam 17, entrance 16 size can be adjusted according to animal build, and the rear port 14 of outer cover 1 is provided with the rear end cap 18 of threaded connection or snapping, circle The edge of shape inlet shroud 15 is sleeved on the inner side of rear end cap 18.
Display, manual/auto switch are provided with controller 8, during using the present apparatus, entrance of the mouse through device is put Enter to breathe in anesthesia outfit, turn on the power and connect anesthesia source of the gas, setting manually or automatically controls, and anesthetic gases is by air inlet pipe 3 Enter return-air chamber 11 into anesthesia chamber 2, and through stomata 12, last cooled via return air pipe 4 enters retracting device;When mouse is initially entered anesthesia During chamber 2, mouse struggles or bearing plate 5 up and down is touched in athletic meeting, upper lower spring 6 is caused to extrude, pressure caused by extrusion spring 6 It can be shown by rheostat 7 on controller 8, with constantly anesthetic gases is passed through, the narcosis of mouse constantly changes, The movement range of mouse can be less and less, until holonarcosis, mouse no longer move, now, the gravity of mouse all concentrates on down On bearing plate, upper bearing plate pressure is zero, is zero when bearing plate pressure reading is gone up in display on the display of controller 8 therefore, under It when bearing plate pressure reading is stable, hand switch can be used to stop anaesthetizing manually, cut-out anesthesia can be also automatically controlled by controller Gas source switch, stop anesthesia.
Although above-mentioned the embodiment of the present invention is described with reference to accompanying drawing, model not is protected to the present invention The limitation enclosed, on the basis of technical scheme, those skilled in the art need not pay creative work and can do The various modifications or deformation gone out are still within protection scope of the present invention.

Claims (10)

1. a kind of experimental animal breathing anesthesia outfit, including outer cover, chamber, air inlet pipe and muffler, and anesthesia source of the gas are anaesthetized, Characterized in that, being provided with pressure sensitive device on the inside of outer cover, the pressure sensitive device includes bearing plate, spring, variable resistance Device and controller, one end of the spring are fixed on outer cover inwall, and the other end is connected with bearing plate, the connection of bearing plate bottom surface Rheostat, rheostat are connected with controller, the front port of outer cover connection air inlet pipe, rear port be provided with threaded connection or The rear end cap of snapping, the rear end cap are connected with inlet shroud, and the edge of the inlet shroud is sleeved on the inner side of the rear end cap.
2. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that the end of the air inlet pipe is set It is equipped with one-way vent valve.
3. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that in the bearing plate and outer cover Connection cloth is sealed between wall.
4. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that the outer cover front portion is provided with Return-air chamber, return-air cavity wall, which is uniformly distributed along the circumference, is provided with stomata, and stomata is communicated in anesthesia chamber and return-air chamber;Return-air cavity outer wall is set There is gas returning port, gas returning port connects with the muffler.
5. experimental animal according to claim 4 breathing anesthesia outfit, it is characterised in that the gas returning port and muffler It is arranged at the top of outer cover.
6. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that the inlet shroud is elastic material Material is made, and entrance is provided with the middle part of the inlet shroud.
7. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that be located in the inlet shroud into It is provided with around mouthful and easily tears seam.
8. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that the outer cover and bearing plate are equal It is made up of insulating materials.
9. experimental animal according to claim 1 breathing anesthesia outfit, it is characterised in that be provided with the controller Display, manual automatic switch.
10. a kind of experimental animal application method of breathing anesthesia outfit, it is characterised in that comprise the following steps:
(1) entrance of the experimental animal through device is put into breathing anesthesia outfit, turns on the power and connect anesthesia source of the gas, hand is set Move or automatically control, anesthetic gases enters anesthesia chamber by air inlet pipe, and enters return-air chamber through stomata, and last cooled via return air pipe enters back Receiving apparatus;
(2) bearing plate up and down that experimental animal is struggled or motion is touched in device, causes to extrude, caused by extruding to upper lower spring Pressure shows that the pressure value on display constantly changes with the continuous motion of animal by rheostat on the controller Become;
(3) being continually fed into anesthetic gases, the depth of anesthesia of animal gradually increase, and the movement range of animal is gradually reduced, Until holonarcosis, animal stop motion, now, the gravity of animal are concentrated on lower bearing plate, upper bearing plate pressure is zero, i.e., When showing that upper bearing plate pressure is zero on display, when lower bearing plate pressure value is stable, stopped manually according to the setting of step (1) Only anaesthetize or control stopping automatically by controller and anaesthetize.
CN201710976932.3A 2017-10-19 2017-10-19 A kind of experimental animal breathing anesthesia outfit and its application method Pending CN107595428A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108720964A (en) * 2018-06-22 2018-11-02 南华大学附属第医院 A kind of integrated anesthesiaing system of animal
CN110025399A (en) * 2019-05-27 2019-07-19 大连理工大学 A kind of middle-size and small-size animal continuous narcosis device of the adjustable suction-type of dosage
CN110269721A (en) * 2018-03-15 2019-09-24 北京慧荣和科技有限公司 Big animal mouth and nose exposure system
CN113100744A (en) * 2021-03-29 2021-07-13 华中科技大学同济医学院附属协和医院 Positioning device for animal nuclear magnetic resonance imaging

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110269721A (en) * 2018-03-15 2019-09-24 北京慧荣和科技有限公司 Big animal mouth and nose exposure system
CN108720964A (en) * 2018-06-22 2018-11-02 南华大学附属第医院 A kind of integrated anesthesiaing system of animal
CN110025399A (en) * 2019-05-27 2019-07-19 大连理工大学 A kind of middle-size and small-size animal continuous narcosis device of the adjustable suction-type of dosage
CN110025399B (en) * 2019-05-27 2024-01-02 大连理工大学 Dose-adjustable inhalation type continuous anesthesia device for small and medium animals
CN113100744A (en) * 2021-03-29 2021-07-13 华中科技大学同济医学院附属协和医院 Positioning device for animal nuclear magnetic resonance imaging

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