CN201807057U - Design and application of novel experimental equipment for sleep deprivation of rat - Google Patents
Design and application of novel experimental equipment for sleep deprivation of rat Download PDFInfo
- Publication number
- CN201807057U CN201807057U CN2009200750661U CN200920075066U CN201807057U CN 201807057 U CN201807057 U CN 201807057U CN 2009200750661 U CN2009200750661 U CN 2009200750661U CN 200920075066 U CN200920075066 U CN 200920075066U CN 201807057 U CN201807057 U CN 201807057U
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- rat
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- sleep
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Abstract
The utility model relates to an experimental apparatus for sleep deprivation of a rat, which is particularly used for watching the fragmented sleep phenomenon. The experimental apparatus consists of three parts, including a box body part (2), a moving part (3) and a control part (4). The experimental apparatus, on one hand, can guarantee free activities, food eating and water drinking of the rat, and one the other hand, can provide intermittent movement at certain speed. The box body part is made of transparent organic glass; the moving part consists of a transmission belt and a rotary shaft and provides intermittent movement; the control part consists of a lower metal box and an inner circuit and controls the moving time and speed of the transmission belt; and the moving time (which is 3s for switching-on and 30s for switching-off) is controlled by a delay relay, and the moving speed (which is 2cm/s) is commonly regulated by a motor speed regulator and a speed-regulating motor.
Description
Technical field
This utility model relates to a kind of experimental apparatus of making rat sleep deprivation model, mainly is applicable to the observation of sleep fragment phenomenon.
Background technology
Sleep fragment (sleep fragmentation) phenomenon is meant by waking (arousal) increased frequency up, causes frequent sleep-wakeup process alternately to occur, and the sleep seriality is destroyed, and deep sleep time and ratio reduce.This phenomenon is ten minutes common phenomena in the sleep associated with disease, and is more and more to the content of its research.But at present the experimentation equipment that carries out sleep deprivation at rat is primarily aimed at full sleep deprivation and optional sleep is deprived, and still lacks the equipment that can clearly make sleep fragment phenomenon.
Summary of the invention
In order to set up the rational animal model of sleep fragment phenomenon, this utility model designs a kind of experimental facilities, can short time, alternating movement by conveyer belt form the waking up of rat (be conveyer belt when static rat can fall asleep, rat is waken up during conveyer belt, and so circulation), and then make the sleep fragment phenomenon of clear and definite rat, and realize the controlled of sleep fragment time that is Sleep-Wake time, so that application when carrying out different experiments research.Because motion stimulates derived components single and degree is light, has reduced the interference of other Confounding Factor.
Description of drawings
Fig. 1 design principle figure of the present utility model.
The structural map of Fig. 2 casing part.
The ideograph of Fig. 3 control and running part.
The specific embodiment
In Fig. 1, casing part (1), motion parts (3) link to each other in turn with control section (4).Rat places casing, and cabinet space guarantees that it is free movable, and can make things convenient for the ad lib water inlet, and box bottom is empty, and rat is movable on the conveyer belt below the casing.Motion parts is made up of conveyer belt and rotating shaft, and intermittent movement is provided.Control section is made up of below metal box and its internal circuit, the movement time and the speed of control conveyer belt.Wherein, the casing part prevents to crush the rat tail and is convenient to clear up the rat Excreta with keeping 1.5cm gap (2) between the conveyer belt of motion parts.Conveyer belt is with the metal box gap 5cm of the control section of below, so that clean.
Fig. 2 shows that casing is made by transparent organic glass, and length=50.0cm is wide=16.5cm, height=30.5cm.Lid (1) is arranged above, is the passage that rat is come in and gone out.There are crib (2) and water fountain interface (3) in the centre, and the bottom has support (4) to support.Crib length=10.0cm, wide=3.0cm, height=10.0cm, preposition steel wire 2mm is thick, and adjacent wires is 1cm at interval.The built-in Mus grain of crib granule guarantees the rat ad lib.Water fountain interface diameter 2cm can external water fountain, guarantees that rat freely drinks water.
In the ideograph of Fig. 3, power supply (2), switch (3), time-delay relay (4), machine governor (5), buncher (6) link to each other successively.By time-delay relay controlled motion time (open 3s, close 30s), machine governor and buncher are regulated and control movement velocity (2cm/s) jointly.At last, motor is by the conveyer belt (1) of the motion parts of band (7) connection synchronously.
Claims (1)
1. novel rat sleep deprivation equipment, form by casing part, motion parts and control section three parts, casing is made by transparent organic glass, motion parts is made up of conveyer belt and rotating shaft, be connected with motor by synchronous band, control section adopts power supply, switch, time-delay relay, machine governor, buncher to connect in turn, realizes the control of conveyer belt interval and speed jointly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009200750661U CN201807057U (en) | 2009-07-22 | 2009-07-22 | Design and application of novel experimental equipment for sleep deprivation of rat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009200750661U CN201807057U (en) | 2009-07-22 | 2009-07-22 | Design and application of novel experimental equipment for sleep deprivation of rat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201807057U true CN201807057U (en) | 2011-04-27 |
Family
ID=43890015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009200750661U Expired - Fee Related CN201807057U (en) | 2009-07-22 | 2009-07-22 | Design and application of novel experimental equipment for sleep deprivation of rat |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201807057U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102919141A (en) * | 2012-09-24 | 2013-02-13 | 中国航天员科研训练中心 | Rat and mouse sleep interferometer |
| CN103654996A (en) * | 2013-11-25 | 2014-03-26 | 温州医科大学附属第一医院 | Special method and device for rat intraperitoneal injection |
| CN109430076A (en) * | 2018-12-17 | 2019-03-08 | 中国医科大学附属第医院 | A kind of device forcing receptor sleep fragmentation |
-
2009
- 2009-07-22 CN CN2009200750661U patent/CN201807057U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102919141A (en) * | 2012-09-24 | 2013-02-13 | 中国航天员科研训练中心 | Rat and mouse sleep interferometer |
| CN102919141B (en) * | 2012-09-24 | 2017-09-22 | 中国航天员科研训练中心 | Big mice sleep interferometer |
| CN103654996A (en) * | 2013-11-25 | 2014-03-26 | 温州医科大学附属第一医院 | Special method and device for rat intraperitoneal injection |
| CN103654996B (en) * | 2013-11-25 | 2015-08-05 | 温州医科大学附属第一医院 | A kind of equipment being exclusively used in rats by intraperitoneal injection |
| CN109430076A (en) * | 2018-12-17 | 2019-03-08 | 中国医科大学附属第医院 | A kind of device forcing receptor sleep fragmentation |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110427 Termination date: 20110722 |