CN201753358U - Oblique and rotary gravity mixed biological reaction unit - Google Patents
Oblique and rotary gravity mixed biological reaction unit Download PDFInfo
- Publication number
- CN201753358U CN201753358U CN2010201036506U CN201020103650U CN201753358U CN 201753358 U CN201753358 U CN 201753358U CN 2010201036506 U CN2010201036506 U CN 2010201036506U CN 201020103650 U CN201020103650 U CN 201020103650U CN 201753358 U CN201753358 U CN 201753358U
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- China
- Prior art keywords
- culture vessel
- biological reaction
- column
- row
- stationary installation
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Abstract
The utility model discloses a biological reaction unit capable of adopting a container with a columnar main body for microcarrier cell culture. One row or a plurality of rows of, one column or a plurality of columns of columnar culture container fixing devices are driven by a motor to rotate in a framework with fixing and supporting effects so as to implement microcarrier cell culture. The columnar culture container fixing devices are mutually parallel and form an angle of 5-80 degrees with a horizontal plane; two groups, three groups or a plurality of groups of fixing hole positions are distributed on the columnar culture container fixing devices in central symmetry manner by surrounding the rotating shafts of the columnar culture container fixing devices and relative to the centers of the rotating shafts; each group of hole positions consists of at least two fixing holes and a support base with support effect at the bottom, wherein the centers of the fixing holes are on the same straight line, and the planes of the fixing holes are in parallel with each other; each row or each column of the columnar culture container fixing devices, as well as each row or each column of the columnar culture container fixing devices and the motor can adopt transmission belts or gears for transmission. The oblique and rotary gravity mixed biological reaction unit can comprise a control circuit part, can be contained in a small temperature control container, and can be directly arranged in a temperature control room.
Description
Technical field
The microcarrier cell cultures is the main method that mass cell is cultivated, and the conventional bio-reactor that is used for the microcarrier cell cultures costs an arm and a leg, and complex structure needs the operator of specialty to use.
The biological reaction apparatus that the utility model relates to is economical and practical, and is simple to operate, makes the microcarrier cell cultures easy as common cell bottle cell cultures.
Background technology
Because traditional rolling bottle culturing cell exists labor capacity big, required bottle quantity is many, and contaminating microorganisms consumes energy greatly easily, produces shortcomings such as dirt is many, and the microcarrier cell culture technology receives publicity day by day.And the bio-reactor of import costs an arm and a leg, and the home-made bio-reactor is cheap, the bad again assurance of culture effect and stability.
The utility model content
In order to address the above problem, it can be that column culture vessel (as 3L rolling bottle etc.) carries out the microcarrier cell cultures by main body that the utility model provides a kind of microcarrier biological reaction apparatus, reaches high-cell density, economical and practical.
The technical scheme that the utility model adopted is: a kind of main body that makes is the biological reaction apparatus that the container of column carries out the microcarrier cell cultures, in the framework that plays fixing and supporting role, rotate by motor drive 1 row or multirow, 1 row or multiple row column culture vessel stationary installation, carry out the microcarrier cell cultures, each column culture vessel stationary installation is parallel to each other and all tilt to be connected in the support frame.
Rotate about it axle on its column culture vessel stationary installation and relatively rotate a revenue centre and be symmetrically distributed with 2 groups, 3 groups or organize fixed hole position more, position, every group of hole by at least 2 centers on same straight line and plane, place fixed orifices parallel to each other and the base for supporting that plays the support effect in the bottom form.
Its each column culture vessel stationary installation parallel to each other and and horizontal plane be 5～80 the degree angles.
Between its each row or each colonnade shape culture vessel stationary installation, can use transmission belt transmission or geartransmission between each row or each colonnade shape culture vessel stationary installation and the electric motor.
It can contain the pilot circuit part, and pilot circuit comprises power switch, electromotor velocity regulating circuit, corresponding button.
It can be placed in the temperature control container.Temperature control container comprises greenhouse, incubator.
Description of drawings
Fig. 1, Fig. 2 are the side-view of two kinds of types of realization the design thinking
Fig. 3 is the frontview of the column culture vessel stationary installation of horizontal positioned
Fig. 4 is the schematic perspective view of spending the column culture vessel stationary installation at angles with horizontal plane journey 5～80
Fig. 5 is frontviews multiple lines and multiple rows and column culture vessel stationary installations horizontal plane journey 5～80 degree angles
(1) framework of its fixed support effect; (2) electric motor; (3) column culture vessel stationary installation; (4) crossbeam; (5) belt or the gear of connection column culture vessel stationary installation; (6) belt or the gear of connection column culture vessel stationary installation and electric motor; (7) fixed hole position of placement column culture vessel; (8) column culture vessel stationary installation rotation axis; (9) fixed orifices of placement column culture vessel; (10) base for supporting of placement column culture vessel;
Embodiment
For feature and advantage of the present utility model can be become apparent more, the utility model is described in further detail below in conjunction with the drawings and specific embodiments.
Fig. 1, Fig. 2 are the side-view of two kinds of types of realization the design thinking, connecting on the crossbeam (4) in framework (1) by 1 row or multirow, 1 row or multiple row is parallel to each other and with the column culture vessel stationary installation (3) at horizontal plane journey 5～80 degree angles, every row or every capable column culture vessel stationary installation (3) are connected by belt or gear (5), and be connected to common electric motor (2) by belt or gear (6), have pilot circuit control motor drive to rotate.
Fig. 3 is the frontview of the column culture vessel stationary installation of horizontal positioned, the fixed hole position (7) that 2 groups, 3 groups or many groups are placed the column culture vessels round its revenue centre symmetric offset spread of rotation axis (8).
Fig. 4 is the schematic perspective view of spending the column culture vessel stationary installation stationary installation at angles with horizontal plane journey 5～80, at least 2 fixed orifices (9) and 1 base for supporting (10) of placing the column culture vessel of placing the column culture vessels on the fixed hole position of each placement column culture vessel.
Fig. 5 is frontviews multiple lines and multiple rows and column culture vessel stationary installation stationary installations horizontal plane journey 5～80 degree angles.
Claims (6)
- One kind can to make main body be the biological reaction apparatus that the culture vessel of column carries out the microcarrier cell cultures, it is characterized in that in the framework that plays fixing and supporting role, by the motor drive multirow, multiple row column culture vessel stationary installation is rotated, carry out the microcarrier cell cultures, each column culture vessel stationary installation is parallel to each other and all tilt to be connected in the support frame.
- 2. biological reaction apparatus according to claim 1, it is characterized in that on the column culture vessel stationary installation of its inclination, rotating about it axle and relatively rotate a revenue centre and be symmetrically distributed with many group fixed hole positions, every group of fixed hole position by at least two centers on same straight line and plane, place fixed orifices parallel to each other and the base for supporting that plays the support effect in the bottom form.
- 3. according to any described biological reaction apparatus in the claim 1～2, it is characterized in that its each column culture vessel stationary installation be parallel to each other and and horizontal plane be 5～80 degree angles.
- 4. according to any described biological reaction apparatus in the claim 1～2, it is characterized in that to use the transmission belt transmission between column culture vessel stationary installation that each row, each row tilt and the electric motor between the column culture vessel stationary installation of Qi Gehang, each row inclination.
- 5. according to any described biological reaction apparatus in the claim 1～2, it is characterized in that it contains the pilot circuit part, pilot circuit comprises power switch, electromotor velocity regulating circuit, corresponding button.
- 6. according to any described biological reaction apparatus in the claim 1～2, it is characterized in that it can be placed in the temperature control container, temperature control container comprises greenhouse, incubator.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201036506U CN201753358U (en) | 2010-01-29 | 2010-01-29 | Oblique and rotary gravity mixed biological reaction unit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201036506U CN201753358U (en) | 2010-01-29 | 2010-01-29 | Oblique and rotary gravity mixed biological reaction unit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201753358U true CN201753358U (en) | 2011-03-02 |
Family
ID=43621090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010201036506U Expired - Lifetime CN201753358U (en) | 2010-01-29 | 2010-01-29 | Oblique and rotary gravity mixed biological reaction unit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201753358U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101805695B (en) * | 2010-01-29 | 2012-06-13 | 福尔生物制药股份有限公司 | Oblique rotational gravity mixed biological reaction equipment |
-
2010
- 2010-01-29 CN CN2010201036506U patent/CN201753358U/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101805695B (en) * | 2010-01-29 | 2012-06-13 | 福尔生物制药股份有限公司 | Oblique rotational gravity mixed biological reaction equipment |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: ZHONGKE BIOLOGICAL PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: FORWELL BIOPHARMACEUTICALS CO., LTD. |
|
| CP03 | Change of name, title or address |
Address after: 065201 No. 1155 Development Zone, Sanhe, Hebei, Yanjiao Patentee after: Zhongke biopharmaceutical Limited by Share Ltd Address before: 065201 Yingbin Road 38-2, Yanjiao Development Zone, Hebei, Sanhe Patentee before: Forwell Biopharmaceuticals Co., Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20110302 |