CN201453418U - Bone marrow concentrator - Google Patents
Bone marrow concentrator Download PDFInfo
- Publication number
- CN201453418U CN201453418U CN200920128747XU CN200920128747U CN201453418U CN 201453418 U CN201453418 U CN 201453418U CN 200920128747X U CN200920128747X U CN 200920128747XU CN 200920128747 U CN200920128747 U CN 200920128747U CN 201453418 U CN201453418 U CN 201453418U
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- bone marrow
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- filter bowl
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Abstract
The utility model discloses a bone marrow concentrator, which relates to medical device. The needle head of a bone marrow refluxing tube (5) which is placed at top of a concentrator mainframe(1) is communicated with a connecting pipe of a medical three-way cock (6), another connecting pipe of the medical three-way cock (6) is communicated with one end of a one-way valve A (7), and the other end of the one-way valve A (7) is communicated with an inlet of a filtering bowl upper cover (8), and another connecting pipe of the medical three-way cock (6) is communicated with one end of a one-way valve B (12), the other end of the one-way valve B (12) is communicated with an outlet at bottom of a filtering bowl container (9), and the bottom of the filtering bowl container (9) is provided with a 280-mesh filtering screen (10) in a sticking way. The starting way is an electric starting, and the electric operating is convenient, the concentrating speed and cycling times can be adjusted according to needs; and the bone marrow concentrator can be used in alternation, therefore, the economic burden of patient is lightened; the functions are controllable, and are controlled by program composition, meanwhile, the functions can be set according to needs, and the presetting can be conducted according to the bone marrow flow rate and the cycling times; furthermore, alarming for faults, alarming for catheter blocking, and alarming for pressure sensing and other functions can be conducted.
Description
Technical field
This utility model relates to armarium, but is fast effective ingredient such as stem cell in the bone marrow and skeletal growth factor to be enriched in the bone renovating material in the selecting cell delay technology art, to reach the bone marrow enricher that improves bone renovating material.
Background technology
The demand of clinical bone renovating material to high osteogenic activity is huge, in annual nearly 500, the 000 routine bone transplant operations of the U.S..By the conventional tissue engineered bone that makes up of cell in vitro amplification is a kind of comparatively ideal bone renovating material, but since the time of its external structure is long, operating technology requires high, disadvantages affect such as medical expense is huge, transportation inconvenience its in Clinical Application.How to make up the tissue engineered bone of high osteogenic activity fast, realize that " with getting with using " of tissue engineered bone become the research focus in tissue engineered bone field.Studies confirm that in the past contains a large amount of skeletonization precursor and bone-inducing factor in the red bone marrow, how effective ingredient many in the bone marrow is applied to the reparation of osseous tissue, is subjected to extensive attention in recent years.Be used for enrichment bone marrow stem cell device at present abroad and have two kinds.A kind ofly be: totally-enclosed hemocyte separation system (COBE 2991TM Cell Processor, GAMBRO BCT.Inc.), its enrichment bone marrow stem cell principle is to utilize the density gradient centrifugation principle that the marrow blood of gathering is carried out quick cell sorting, the bone marrow composition is with the density gradient layering, be respectively plasma layer, bone marrow nucleated cell (nucleated cells from the inside to the outside, NCs) layer and bone marrow mature erythrocyte layer, and mesenchymal stem cells MSCs (BMSCs) progressively is enriched in the bone marrow nucleated cell layer in centrifugal.By distribution pipeline, with the output one by one in centrifugal of different bone marrow compositions, packing is reclaimed.The shortcoming of this device is only to make the stem cell in the bone marrow obtain enrichment, and has lacked other many effective ingredient in the bone marrow, as the osteogenic induction factor, platelet etc.Second kind is: CELLECT enricher (U.S. Depuy company), the operation principle of CELLECT enricher is manually a bone marrow backflow tube piston to be depressed, the elastic force of applied spring device promotes piston and produces negative pressure resorption bone marrow, bone marrow aspiration in will filtering bowl by the conduit that is connected with the tube that refluxes, make slowly flow through enrichment host material in the filter bowl of bone marrow, suitable mesh-structured and good cell is sticked ability to utilize the enrichment host material, when being flowed through, bone marrow optionally sticks the delay bone marrow stem cell, skeletal growth factor, effective ingredient such as platelet, thus make compositions such as bone marrow stem cell all be able to enrichment.After enrichment is for the first time finished, manually press the tube piston that refluxes once more and carry out the enrichment that circulates the second time, finish until enrichment so repeatedly; The device of the control CELLECT enricher spring rate of climb is to be connected with the airway that diameter is about 0.5mm at bone marrow backflow tube bottom, is used to control the speed of the turnover of air with the control spring rising.But there is following shortcoming in this device: 1, manual operation inconvenience; 2, the bone marrow flow velocity is non-adjustable, can not regulate the flow velocity of bone marrow according to the needs of host material; 3, cycle-index is non-adjustable, can not the regulation and control cycle-index be set by program; 4, this device is disposable use, cost consumptive material costliness.
Summary of the invention
The purpose of this utility model is an a electronic bone marrow enricher of design, and its bone marrow flow velocity and cycle-index can be by the regulation and control of enricher main frame, for making up the bone marrow enricher of the bone renovating material of high osteogenic activity fast.
The technical scheme that the purpose of this utility model adopted is, the motor output shaft that comprises the enricher main frame is connected with nut by shaft coupling, nut and screw mandrel engagement, card has the piston crown disk in the draw-in groove groove of one end drive link of screw mandrel, piston is placed in the bone marrow backflow tube tube, medical three-way cock, check valve A, filter bowl loam cake is arranged at filter bowl container top, 280 mesh filter screens, filter bowl container is placed on the filter bowl base, check valve B, the syringe needle of the bone marrow backflow tube that place at its described enricher main frame top is connected a connection tube of medical three-way cock, another root connection tube of medical three-way cock is connected the end of check valve A, the other end of check valve A is connected the import of filter bowl loam cake, another connection tube of medical three-way cock connected the end of check valve B, the other end of check valve B is connected the outlet of filter bowl container bottom, is pasted with 280 mesh filter screens at the bottom of the filter bowl container bowl.
Work process of the present utility model: 1, equipment self-inspection: after turning on the power switch, machine can carry out self check according to the self-check program that is provided with in advance, makes other working procedure all be in the preparation state.2, the bone renovating material that will implant is put into filter bowl container, neat as far as possible when laying bone renovating material, reduce the space between the material, reduce bone marrow as far as possible and flow away from the space between the material, reach bone marrow and farthest in material void, filter, with the cell in the enrichment bone marrow farthest.3, according to what (in ratios of 1g PLL-DBM:10ml bone marrow) of bone renovating material, extraction is an amount of, and (30～120mL) marrow bloods, bone marrow extraction-type are carried out in strict accordance with aseptic principle, and use the moistening syringe inwall of 1～2ml heparin with anticoagulant in advance.4, at this moment select to be provided with cycle-index and optimum flow rate on control panel, optimum flow rate is by every 100ml bone marrow/minute calculating, and optimum cycle number of times and optimum flow rate draw through the check optimization of parameter.The anticoagulant marrow blood that 5, will extract in advance injects the filter bowl container that fills bone renovating material.6, carry out enrichment by the enlightenment requirement, under the effect of motor transmission bar, an interlock bone marrow backflow piston rises, and the marrow blood in the enrichment process in the filter bowl container enters into bone marrow backflow tube according to certain flow velocity filtration bone renovating material by check valve.7, a bone marrow backflow tube piston presses down bone marrow is re-injected a filter bowl container, enters for the second time and circulates, and the cycle-index according to default finishes until enrichment.8, the bone renovating material that enrichment is finished (DBM or PLL-DBM) takes out from filter bowl container, operation implantable bone defective region.
The utlity model has: Starting mode is electronic, and electric operating is convenient, can regulate enrichment speed and cycle-index on demand; Can use the financial burden that has alleviated patient by turns; The function controllability is controlled by programming, and can carry out the setting of function as required, carries out pre-seting of bone marrow flow velocity and cycle-index, and function such as practicable false alarm, pipe obstruction warning, pressure sensitive warning.
Description of drawings
Further specify this utility model below in conjunction with accompanying drawing.
Accompanying drawing is this utility model structural representation.
Among the figure: the medical three-way cock 7-of a 1-enricher main frame 2-drive link 3-draw-in groove 4-piston 5-bone marrow backflow tube 6-check valve A 8-filter bowl loam cake 9-filter bowl container 10-280 mesh filter screen 11-filter bowl base 12-check valve B
The specific embodiment
As shown in drawings, the motor output shaft that comprises enricher main frame 1 is connected with nut by shaft coupling, nut and screw mandrel engagement, card has piston 4 head disks in draw-in groove 3 grooves of one end drive link 2 of screw mandrel, piston 4 is placed on bone marrow and refluxes in 5 in the tube, medical three-way cock 6, check valve A7, filter bowl loam cake 8 is arranged at filter bowl container 9 tops, 280 mesh filter screens 10, filter bowl container 9 is placed on the filter bowl base 11, check valve B12, the syringe needle of the bone marrow backflow tube 5 that place at its described enricher main frame 1 top is connected a connection tube of medical three-way cock 6, another root connection tube of medical three-way cock 6 is connected the end of check valve A7, the other end of check valve A7 is connected the import of filter bowl loam cake 8,6 another connection tubes of medical three-way cock are connected the end of check valve B12, the other end of check valve B12 is connected the outlet of filter bowl container 9 bottoms, is pasted with 280 mesh filter screens 10 at the bottom of 9 bowls in the filter bowl container.
Claims (1)
1. bone marrow enricher, the motor output shaft that comprises enricher main frame (1) is connected with nut by shaft coupling, nut and screw mandrel engagement, card has piston (4) head disk in draw-in groove (3) groove of one end drive link (2) of screw mandrel, piston (4) is placed in bone marrow backflow tube (5) tube, medical three-way cock (6), check valve A (7), filter bowl loam cake (8) is arranged at filter bowl container (9) top, 280 mesh filter screens (10), filter bowl container (9) is placed on the filter bowl base (11), check valve B (12), it is characterized in that: the syringe needle of the bone marrow backflow tube (5) that place at described enricher main frame (1) top is connected a connection tube of medical three-way cock (6), another root connection tube of medical three-way cock (6) is connected the end of check valve A (7), the other end of check valve A (7) is connected the import of filter bowl loam cake (8), another connection tube of medical three-way cock (6) connected the end of check valve B (12), the other end of check valve B (12) is connected the outlet of filter bowl container (9) bottom, and filter bowl container (9) the bowl end is pasted with 280 mesh filter screens (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200920128747XU CN201453418U (en) | 2009-09-07 | 2009-09-07 | Bone marrow concentrator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200920128747XU CN201453418U (en) | 2009-09-07 | 2009-09-07 | Bone marrow concentrator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201453418U true CN201453418U (en) | 2010-05-12 |
Family
ID=42380759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200920128747XU Expired - Fee Related CN201453418U (en) | 2009-09-07 | 2009-09-07 | Bone marrow concentrator |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201453418U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103952296A (en) * | 2014-01-14 | 2014-07-30 | 卢建熙 | Multifunctional medical treatment substance body combiner |
| CN116948783A (en) * | 2023-07-26 | 2023-10-27 | 重庆富沃思医疗器械有限公司 | Device and method for enriching active ingredients in bone marrow blood |
-
2009
- 2009-09-07 CN CN200920128747XU patent/CN201453418U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103952296A (en) * | 2014-01-14 | 2014-07-30 | 卢建熙 | Multifunctional medical treatment substance body combiner |
| CN103952296B (en) * | 2014-01-14 | 2018-11-30 | 卢建熙 | Multi-functional therapeutic treatment substance bluk recombination device |
| CN116948783A (en) * | 2023-07-26 | 2023-10-27 | 重庆富沃思医疗器械有限公司 | Device and method for enriching active ingredients in bone marrow blood |
| CN116948783B (en) * | 2023-07-26 | 2024-02-23 | 重庆富沃思医疗器械有限公司 | Device and method for enriching active ingredients in bone marrow blood |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100512 Termination date: 20170907 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |