CN201164667Y - Transcranial magnetic stimulator with adjustable stimulation intensity - Google Patents
Transcranial magnetic stimulator with adjustable stimulation intensity Download PDFInfo
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- CN201164667Y CN201164667Y CNU2008200655376U CN200820065537U CN201164667Y CN 201164667 Y CN201164667 Y CN 201164667Y CN U2008200655376 U CNU2008200655376 U CN U2008200655376U CN 200820065537 U CN200820065537 U CN 200820065537U CN 201164667 Y CN201164667 Y CN 201164667Y
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Abstract
The utility model discloses a transcranial magnetic stimulator, the stimulus intensity of which can be modulated. The transcranial magnetic stimulator is composed of a high voltage charging power supply 1, a current-limiting resistor 2, an energy-storage capacitor 3, a reverse freewheeling diode 4, a thyristor switch 5, a magnetic stimulation coil 6 and a micro-computer controller 7, and is characterized in that an upper-end sampling resistance 8, a lower-end sampling resistance 9 and a comparator 10 are also included, wherein, a voltage dividing and sampling circuit composed of the upper-end sampling resistance 8 and the lower-end sampling resistance 9 is connected with the energy-storage capacitor 3 in series, the midpoint is connected with the cathode input end of the comparator 10, the micro-computer controller 7 is connected with the anode input end of the comparator for modulation input according to the predetermined sequence of the modulation waveform, which serves as the given voltage, and the output end of the comparator 10 is connected with the control end of the high voltage charging power supply 1. The transcranial magnetic stimulator enables the magnetic output density to change at any moment, and enables the induced current in the body to accordingly change. The output waveform of the multi-parameter dynamic modulation enables the magnetic stimulation change to be abundant, the feeling is fresh, and the adaptability and the tolerance are not easy to produce, thereby improving the therapeutic effect.
Description
Technical field
This utility model relates to a kind of stimulus intensity can synthetic transcranial magnetic field stimulator, and a kind of have an output modulation function, and the size of stimulating coil output current is serializing, modulationization, and variation, output parameter is by the transcranial magnetic field stimulator of computer program control.
Background technology
Transcranial magnetic field stimulate be in the stimulating coil moment (200 is delicate) pulse current by thousands of amperes, according to electromagnetic induction principle, produce pulsed magnetic field around the coil perpendicular to coil plane, the magnetic field of transition can be lossless by scalp and skull, result from the opposite faradic current of stimulating coil in brain inside, if current's intensity reaches the threshold potential of nerve fiber, just can cause the depolarization of cell membrane potential, and cause the excitement of nervus centralis.This phenomenon occurs in peripheral nervous equally, because magnetic stimulation is undamped by human body, and not damaged, no pain, contactless, the essence of magnetic stimulation is the electricity irritation of body induced currents, but obviously is better than electricity irritation.Therefore be widely used in the research of neuroscience, clinical medical diagnosis, treatment and rehabilitation.The principle of magnetic stimulation is to charge to storage capacitor with DC high-voltage power supply, discharge to stimulating coil as electrical switch with controllable silicon, huge pulse current makes coil produce powerful pulsed magnetic field, the magnetic field of transition can make during near human body organization internal produce faradic current, thereby cause the neurocyte excitement, muscle contraction, hormone secretion touches a series of biological effects such as prominent modulation.
At present, the magnetic field stimulator on the market is divided into manual stimulation and Automatic Program stimulus modelity, and manually stimulating is by press button, the manual triggers reverse-blocking tetrode thyristor, and the single stimulation of formation, frequency is less than 1Hz, and being called the single of low frequency stimulates.Can cause neural once impulsion, the once contraction of innervation flesh, the nerve that is suitable for taking exercises brings out the inspection of current potential.Automatically stimulate to the repetitive stimulation under the computer program control, be called the high frequency repetitive stimulation when frequency is higher than 1Hz, be mainly used in the treatment of nerve, mental sickness.As stimulate brain, and treatment depression, apoplexy sequela, in rehabilitation medicine, being used for functional magnetic stimulates, treatment constipation and gatism.
Present magnetic field stimulator has only constant sequence (clump shape) stimulation of intensity in single stimulation and the stimulation in treatment, effect of stimulation makes the people feel unexpected and dull, with low uncertainty, uncomfortable, is easy to generate adaptability, toleration, and therapeutic effect is descended.
Summary of the invention
Stimulate output shortcoming with low uncertainty in order to overcome existing transcranial magnetic field stimulator, for the comfort that improves when treatment, in order to reduce the adaptability in the treatment, improve the sensitivity of treatment, strengthen therapeutic effect, this utility model provides a kind of stimulus intensity can synthetic transcranial magnetic field stimulator, the magnetic field output intensity is changed at any time, intravital faradic current is also changed thereupon.It is abundant that the output wave mode of multiparameter dynamic modulation changes magnetic stimulation, feels fresh, is not easy to produce adaptability and toleration, thereby improve therapeutic effect.
A kind of stimulus intensity can synthetic transcranial magnetic field stimulator, it comprises high voltage charging power supply 1, current-limiting resistance 2, storage capacitor 3, reverse fly-wheel diode 4, reverse-blocking tetrode thyristor 5, magnetic stimulation coil 6 and microcomputer controller 7, it is characterized in that: it also comprises upper end sample resistance 8, lower end sample resistance 9 and comparator 10, the pressure sampling circuit that upper end sample resistance 8 and lower end sample resistance 9 are formed is connected in parallel on the storage capacitor 3, mid point is received the negative input of comparator 10, microcomputer controller 7 is according to the sequence that is provided with of modulation waveform, the positive pole of receiving comparator input terminal as given voltage is as the modulation input, and the outfan of comparator 10 connects the control end of high voltage charging power supply 1.
Principle of the present utility model is: the modulating wave of various variations and the stimulus frequency of variation (carrier wave) are sent by microcomputer controller simultaneously, through sample circuit sampling and the charging of comparator control storage capacitor, make storage capacitor voltage reach the modulating wave set-point, trigger the controllable silicon electrical switch by microcomputer controller again, realize that magnetic field output energy changes along with the conversion of modulating wave and carrier wave, becomes two dynamic amplitude modulation frequency-modulated waves.
The modulating wave instruction repertorie of microcomputer controller 7 is finished various modulation waveforms through PWM output by filter shape;
High voltage charging power supply 1 charges to storage capacitor 3 by current-limiting resistance 2 under the control of comparator 10;
The pressure sampling circuit of being made up of upper end sample resistance 8 and lower end sample resistance 9 detects the voltage of storage capacitor 3, by the be provided with sequence of microcomputer controller 7 according to modulation waveform, the positive pole of receiving comparator input terminal as given voltage is as the modulation input, when the voltage of storage capacitor 3 is charged to the voltage of modulation waveform setting, comparator 10 output electronegative potentials, allow high voltage charging power supply 1 quit work, send carrier pulse by microcomputer controller 7 again, trigger reverse-blocking tetrode thyristor 5 conductings, finish discharge by reverse-blocking tetrode thyristor to magnetic stimulation coil 6 by storage capacitor 3; Finish the whole modulating wave cycle successively.
The mathematical model of various waveforms is set by microcomputer, change the different variablees in the mathematical formulae, change modulation waveform, on computer screen, show multiparameter dynamic modulation waveform, carrier frequency, output, accumulative total stimulates number, stimulation time, modulation waveform is one or more in the following waveform: sine wave, square wave, triangular wave, trapezoidal wave, staircase waveform, sawtooth waveforms, exponential wave, the differential ripple, the integration ripple, increase progressively, the wave of oscillation successively decreases, its modulation depth, modulating wave is wide, sawtooth waveforms, exponential wave, the differential ripple, the time of integration ripple rising edge and trailing edge, the platform time of trapezoidal wave, staircase waveform progression, the equal scalable of number of repetition is compiled into the output waveform sequential chart, become the abundant therapeutic scheme of conversion, with its storage with call.
The beneficial effects of the utility model are that the output wave mode of multiparameter dynamic modulation makes the magnetic stimulation variation abundant, feel fresh, are not easy to produce adaptability and toleration, thereby improve therapeutic effect.
Description of drawings
Fig. 1 is the circuit theory diagrams of this utility model embodiment.
Fig. 2 is the sketch map of frequency modulation output waveform and sinusoidal modulation wave.
Fig. 3 is the sketch map of square wave, triangular wave, sawtooth waveforms.
Fig. 4 is the sketch map of trapezoidal wave, staircase waveform, differential ripple and integration ripple.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is further specified.
The explanation of Fig. 1 labelling: 1-high voltage charging power supply, 2-charging current limiter resistance, 3-storage capacitor, the reverse fly-wheel diode of 4-, 5-reverse-blocking tetrode thyristor, 6-stimulating coil, 7-microcomputer controller, 8-upper end sample resistance, 9-lower end sample resistance, 10-comparator.
Among Fig. 2, on to arrange waveform be general sequence (clump shape) waveform, centre be harmonic shape between sine, following row is a sine company harmonic shape.
Among Fig. 3, last row is the square-wave frequency modulation waveform, and the centre is the triangular modulation waveform, and following row is the sawtooth waveforms modulation waveform.
Among Fig. 4, last row is the trapezoidal wave modulation waveform, and the centre is the staircase waveform modulation waveform, and following row is differential ripple and integration ripple modulation waveform.
The realization of modulating wave through PWM output, is finished various modulation waveforms by filter shape by the modulating wave instruction repertorie of microcomputer controller 7 in Fig. 1.High voltage charging power supply 1 is subjected to the control of comparator 10, when comparator 10 is output as high potential, high voltage charging power supply 1 work is also passed through current-limiting resistance 2 to storage capacitor 3 chargings, form pressure sampling circuit by upper end sample resistance 8 and lower end sample resistance 9, detect the voltage of storage capacitor 3, and receive the negative input of comparator 10, by the be provided with sequence of microcomputer controller 7 according to modulation waveform, the positive pole of receiving comparator input terminal as given voltage is as the modulation input, when the voltage of storage capacitor 3 is charged to the voltage of modulation waveform setting, sampling voltage is little when being higher than given voltage, comparator 10 output electronegative potentials allow high voltage charging power supply 1 quit work, and send carrier pulse by microcomputer controller 7 again, trigger reverse-blocking tetrode thyristor 5 conductings, finish discharge by reverse-blocking tetrode thyristor to magnetic stimulation coil 6 by storage capacitor 3; Finish the whole modulating wave cycle successively.
In Fig. 2, last row is the train wave output waveform of frequency modulation; Stimulus frequency in its train wave changes, amplitude inconvenience.
Middle row is the sinusoidal wave intermittently modulation of programming, and it is provided with parameter and comprises Sine Modulated wave frequency (ripple is wide), modulation amplitude (modulation depth), intermittent time, carrier frequency, maximum output, minimum output.Its mathematical model is:
Wherein T is train wave working cycle (carrier cycle), and A is a modulation amplitude, and N represents the train wave number in the work pulsewidth.
Following row figure is the continuous modulation of several sine waves, and output time prolongs, and the intermission shortens.Its mathematical model is:
f(t)＝Asin(2πf
0t)
F wherein
0The expression modulating frequency, A is a modulation amplitude.
In Fig. 3, last row adds an intermittence after two square waves connect accent.
Wherein T is a carrier cycle, and N represents the train wave number in the work pulsewidth.M represents segments, and every period is NT/M, A
i, i=1,2 ... M is every section a amplitude,
Middle row is single triangular modulation waveform,
Wherein T is the train wave working cycle, and A is an amplitude, and N represents the train wave number in the work pulsewidth.
Following row is the sawtooth waveforms modulation waveform, the amplitude of triangular wave, time-histories, and the upper edge of sawtooth waveforms, fall time, modulation amplitude all can independently be set.Mathematical model is
Wherein T is the train wave working cycle, and A is an amplitude, and N represents the train wave number in the work pulsewidth.T
mExpression sawtooth waveforms modulation signal maximum time corresponding point.
In Fig. 4, last row can be provided with rise time, fall time, platform time for the trapezoidal wave modulation, intermittent time, modulation degree, carrier frequency, and output.Mathematical model is:
Wherein T is the train wave working cycle, and A is an amplitude, and N represents the wide interior train wave number of modulating wave.T
1And T
2Be starting point and the terminal point of plateau.
Middle waveform is the staircase waveform modulation, and the parameter that can be provided with is: the ladder number, and the ladder time-histories, ladder percentage ratio is differential, minimum and the differential ratio of maximum.
Wherein T is the train wave working cycle, and A is an amplitude, and N represents to modulate the train wave number in the pulsewidth.
Following row is differential ripple and integration ripple (exponential wave and logarithm ripple), and the initial variation of differential ripple is little, converted quantity in time increase and exponentially increases, the integration phase of wave is anti-, initial variable quantity is big, changes little subsequently.Its mathematical model is:
Wherein T is a carrier cycle, and A is an amplitude, and N represents to modulate the train wave number in the pulsewidth.Change the convex-concave degree that the b value can change adjustment curve.
Modulation described in the utility model is exactly that the waveform of various markizations is loaded in original constant sequence (clump shape) magnetic stimulation, load sine wave, square wave, triangular wave, trapezoidal wave, staircase waveform, sawtooth waveforms, exponential wave, logarithm ripple, (differential, the integration ripple) wave of oscillation that increases progressively, successively decreases, can change modulation wave frequency and modulation depth, and the magnetic stimulation frequency also can change, and becomes two dynamic modulation magnetic stimulations.Multiple composite wave modulation stimulates, and produces comfortable joyful stimulation, and changeful stimulation makes magnetic stimulation more acceptant, reaches better therapeutic.
Claims (1)
1, a kind of stimulus intensity can synthetic transcranial magnetic field stimulator, it comprises high voltage charging power supply (1), current-limiting resistance (2), storage capacitor (3), reverse fly-wheel diode (4), reverse-blocking tetrode thyristor (5), magnetic stimulation coil (6) and microcomputer controller (7), it is characterized in that: it also comprises upper end sample resistance (8), lower end sample resistance (9) and comparator (10), the pressure sampling circuit that upper end sample resistance (8) and lower end sample resistance (9) are formed is connected in parallel on the storage capacitor (3), mid point is received the negative input of comparator (10), microcomputer controller (7) is according to the sequence that is provided with of modulation waveform, the positive pole of receiving comparator input terminal as given voltage is as the modulation input, and the outfan of comparator (10) connects the control end of high voltage charging power supply (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200655376U CN201164667Y (en) | 2008-01-29 | 2008-01-29 | Transcranial magnetic stimulator with adjustable stimulation intensity |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200655376U CN201164667Y (en) | 2008-01-29 | 2008-01-29 | Transcranial magnetic stimulator with adjustable stimulation intensity |
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| CN201164667Y true CN201164667Y (en) | 2008-12-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNU2008200655376U Expired - Lifetime CN201164667Y (en) | 2008-01-29 | 2008-01-29 | Transcranial magnetic stimulator with adjustable stimulation intensity |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110180083A (en) * | 2019-06-30 | 2019-08-30 | 南京伟思医疗科技股份有限公司 | A kind of avoid-dismantle coil switching magnetic stimulator and Neural stem cell method |
-
2008
- 2008-01-29 CN CNU2008200655376U patent/CN201164667Y/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110180083A (en) * | 2019-06-30 | 2019-08-30 | 南京伟思医疗科技股份有限公司 | A kind of avoid-dismantle coil switching magnetic stimulator and Neural stem cell method |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20081217 |
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| CX01 | Expiry of patent term |