CN102886102B - Mirror movement neuromodulation system - Google Patents
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Abstract
The invention discloses a mirror movement neuromodulation system, which comprises a plurality of lead biological signal amplifiers, a microcomputer controller, a plurality of lead functional electric stimulators and a micro-current direct-current constant-current stimulator. The principle that functional electric stimulation and transcranial direct-current electric stimulation techniques and mirror movement neurons participate in movement control is applied comprehensively, the biological signal amplifiers, the functional electric stimulators for simulating integrated electromyography envelope signal control, and the micro-current direct-current constant-current stimulator are integrated through the microcomputer controller, myoelectric activity envelope signals are generated by processing myoelectric signals of a plurality of muscle groups which move functionally by using an uninjured side limb, and the plurality of functional electric stimulators are modulated and controlled, so that the same mirror action is generated by the plurality of muscle groups of an injured limb on an opposite side according to uninjured side myoelectric information, brain functional regulation and reconstruction are realized, the plasticity of neuronal synapsis and the recovery of neurological functions are facilitated, and the treatment effect of sports rehabilitation is achieved.
Description
Technical field
The present invention relates to neural rehabilitation technique field, relate in particular to a kind of mirror movements neuromodulation system for hemiplegia patient treatment after apoplexy and central nervous system injury.
Background technology
Central nervous system pathological change usually causes human motion dysfunction, and modal is inclined to one side side quadriplegia, affects greatly patient's work and life, and has also brought white elephant to family and society.
Traditional medical rehabilitation means are mainly that its Therapeutic Method and therapeutic effect are limited by acupuncture, massage, physical exercise therapy and the passive treatment of physical therapy.In recent years along with scientific research and the development of neuroscience and clinical rehabilitation medicine, the nervimotion therapy of some new nervous physiology theories and delayed ischemic neurological deficits is successively proposed, such as the regeneration of nerve injury, reconstruction, function compensation is theoretical, motor relearning is theoretical, functional electric stimulation (FES), biofeedback therapy, the new Therapeutic Method such as therapy, transcranial magnetic stimulation therapy, robot assisted treatment are observed in forced movement therapy, motion imagination therapy, action, and utilize recently visual feedback, see the strong lateral movement of mirror mirror movements therapy.These treatments have often only utilized partial nerve movement mechanism to promote rehabilitation, and curative effect is unsatisfactory.Neural controlled motion is sensation, motion driving, emotion, the common result regulating in multi-functional, the multiple neural feedback of memory loop, therefore will increase neural rehabilitation and will transfer more neuron participation as far as possible.
Mirror neuron is the new discovery of Neuroscience Research in recent ten years, within 1996, first find that monkey class just has discharge activities to make the mirror image nerve of echopraxia while seeing action, application magnetic resonance in 1998 and transcranial magnetic stimulation technology find that again human brain multiple location equally also has mirror neuron system.Studies have shown that mirror image nervous system is the neuro-physiological mechanism of movement observation, the imagination, imitation, study and nerve function rebuilding.
Through cranium galvanic stimulation (tDCS), it is a kind of ancient and new electrotherapy method of re-recognizing, rediscovering.Use noinvasive weak current, regulate the tranquillization level of brain nervous cell transmembrane potential with the model of action of electric field polarization, the local potential of the cell that affects the nerves, changes excited threshold value, and positive polar stimulation can make nerve excitability increase, and negative pole stimulates inhibition function of nervous system.With negative pole stimulate strong side brain, positive polar stimulation Ipsilateral brain can direct excited Ipsilateral brain, suppress the inhibition of strong side cortex to Ipsilateral.
Summary of the invention
Main purpose of the present invention is to provide a kind of rehabilitation system of mirror movements neuromodulation as master of take, be intended to utilize more motion assist mechanism to realize brain function regulation and control and rebuild, promote the plasticity of nerve synapse and the rehabilitation of function of nervous system, improve central hemiplegic patient's therapeutic effect.
In order to achieve the above object, the present invention proposes a kind of mirror movements neuromodulation system, comprising: some bio-signals amplifiers that lead, the information of the surface electromyogram signal while being good for side limb activity for gathering;
Microcomputer controller, for described surface electromyogram signal is processed, forms the dynamic myoelectricity envelope shape command signal of analog integration;
Some functional electrical stimulatos that lead, for according to the dynamic myoelectricity envelope shape command signal of described strong side limbs analog integration, produce the mirror movements of similar synchronous with the image current stimulation offside affected limb of equal proportion motion.
Preferably, described some bio-signals amplifiers that lead have detecting electrode, and described detecting electrode is attached to the respective muscle position of the strong side limbs of patient; Described some functional electrical stimulatos leading have stimulating electrode, and described stimulating electrode is attached to the corresponding muscle position of patient's affected limb.
Preferably, this system also comprises: processor, be connected between described bio-signals amplifier and microcomputer controller, and for described surface electromyogram signal being carried out to AD conversion, amplification, rectification, filtering and integrating circuit, process.
Preferably, the mode that described microcomputer controller is processed described surface electromyogram signal comprises: AD conversion, digital filtering and wavelet analysis are processed.
Preferably, this system also comprises: micro-current DC constant current stimulator, be connected with described microcomputer controller, its anodal head position that connects the cortical representation of affected limb, negative pole connects the corresponding head surface of strong side, for when periphery limbs produce mirror movements, and the collaborative cerebral cortex neurons that stimulates of micro-current DC electricity irritation of head, the irritability that regulates and increase Ipsilateral brain, promotes the recovery of impaired cortex hormone function jointly.
What preferably, described micro-current DC constant current stimulator was selected is high voltage operational amplifier and constant-current source circuit.
Preferably, the stimulating current of described micro-current DC constant current stimulator is less than 5mA.
Preferably, described microcomputer controller also triggers described functional electrical stimulato for time delay, makes the time delay of affected limb muscular irritation time synchronized, produces the phase alternation motion of strong side limbs and affected limb.
Preferably, described bio-signals amplifier is low noise high impedance instrument amplifier; What described microcomputer controller was selected is ARM series monolithic.
Preferably, the information of described surface electromyogram signal at least comprises one of following: the activity sequential between the amplitude of electromyographic signal, waveform, activity time, intermittent time, each muscle group.
A kind of mirror movements neuromodulation system that the present invention proposes, integrated application FES, tDCS technology and mirror movements neuron participate in the principle of motor control, utilize bio-signals amplifier, the functional electrical stimulato that simulation myoelectricity integration envelope signal is controlled, micro-current DC constant current stimulator is under the integration of microcomputer controller, integrated, utilizes strong side limbs to carry out the electromyographic signal of some muscle groups of functional activation, through amplifying, rectification, filtering, sampling and Mathematical treatment, produce the myoelectrical activity envelope signal of some functional activity muscle groups, and modulate and control some functional electric stimulations that lead with this, makes some muscle groups of the ill limbs of offside according to the activity intensity of strong pleural muscle electricity, Strength Changes, contraction time, intermittent time, the mirror image action that activity timing sequence generating is same, without mirror, patient can see and feel that the synchronous mirror of bilateral limbs is movable or functional mirror image is movable, gives full play to patient's mirror image neural, sensory nerve, nervus motorius and motion idea, the nervus centraliss such as motor feedback, the reflex arcs such as peripheral nervous, realize brain function regulation and control and rebuild, and promote the plasticity of nerve synapse, promote the rehabilitation of function of nervous system, thereby reach the therapeutic effect of athletic rehabilitation.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of mirror movements neuromodulation system of the present invention preferred embodiment;
Fig. 2 is the work process schematic diagram of mirror movements neuromodulation system of the present invention.
In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the present invention is further elaborated.
The specific embodiment
Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
It is historical that mirror neuron system is found existing more than ten years.When the mankind see a kind of new behavior, while imitateing this behavioral activity, one group of brain premotor area special cells has electric discharge phenomena, and therefore named is mirror neuron, no matter be, makes their own action, still see that others makes same action, mirror neuron all can be activated, and its function is to help human motion study, and simulation is imitated, being the important anatomical physiology basis that nervus motorius network is rebuild, is also the basis of understanding other people behavior.
Current discovery mirror neuron is widely distributed brain, and premotor cortex, top, temporal lobe and island leaf all can be seen a large amount of mirror neurons.In addition also have a class mirror neuron, when observing new element, behavior, language, countenance and body gesture, activate.Another kind of mirror neuron is activating when the idea after understanding was observed is just now gone in people's attempt.When the idea of being initiatively familiar with, imitating, learning as people strengthens, mirror neuron activates, and when cortical excitability improves, the activity of mirror image nerve can make the motor function improvement of limbs.
Mirror image therapy is also a kind of new athletic rehabilitation Therapeutic Method: for example: mirror is placed in the middle of the limbs of both sides with certain angle; pathological changes limbs be cannot see at mirror reverse side; make patient watch the strong side limbs in mirror attentively; mirror image is movable simultaneously to make patient both sides limbs; because affected limb is hidden by mirror all the time; patient see pathological changes limbs can activity in mirror freely; be the non-invasive neural study method for reconstructing that a kind of patient initiatively participates in, effective to the rehabilitation of hemiplegic patient after apoplexy and central nervous system injury.
TDCS is also a new technique of re-recognizing, and both combine to use and can strengthen therapeutic effect.
The present invention is just based on above-mentioned principle, adopt bilateral active exercise and strong lateral wall to help Ipsilateral mirror movements the auxiliary thinking through cranium galvanic stimulation, make full use of multiple nervimotion modulation scheme, active exercise, action observation, mirror movements, imagery motion, biofeedback motion, bilateral movement body sense reflection, functional electric stimulation, through cranium HVDC Modulation technology, integrating, is a kind of brand-new neural rehabilitation Comprehensive Treatment technology.The present invention gives full play to reflex arc, micro-direct currents such as nervus centralis, peripheral nervous such as patient's mirror image nerve, sensory nerve, nervus motorius and motion idea, movable body sense feedback cerebral cortex function is modulated, realize the modulation of Ipsilateral brain and rebuild, promote the plasticity of nerve synapse, promote the rehabilitation of function of nervous system, thereby reach the therapeutic effect of athletic rehabilitation.
Particularly, as shown in Figure 1, preferred embodiment of the present invention proposes a kind of mirror movements neuromodulation system, be mainly used in treating rehabilitation training and the treatment of central hemiplegic patient, this mirror movements neuromodulation system comprises: some bio-signals amplifiers that lead 1, microcomputer controller 2, some functional electrical stimulatos leading 3, wherein:
The input of bio-signals amplifier 1 has detecting electrode 11, the input of functional electrical stimulato 3 has stimulating electrode 31, the detecting electrode 11 of the input of some bio-signals amplifiers that lead 1 and the stimulating electrode 31 of some functional electrical stimulatos that lead 3, form with lamellar is attached to respectively strong side (measurement myoelectricity), Ipsilateral is muscle group body surface position one to one, the detecting electrode 11 that is bio-signals amplifier 1 is attached to the respective muscle position that patient is good for side limbs, the stimulating electrode 31 of functional electrical stimulato 3 is attached to the corresponding muscle position of patient's affected limb.
The information of surface electromyogram signal when bio-signals amplifier 1 is good for side limb activity for gathering, the information of this surface electromyogram signal comprises the activity sequential between the amplitude of electromyographic signal, waveform, activity time, intermittent time, each muscle group etc.
Microcomputer controller 2, for described surface electromyogram signal is processed, forms the dynamic myoelectricity envelope shape command signal of analog integration; The mode that 2 pairs of described surface electromyogram signals of described microcomputer controller are processed comprises: AD conversion, digital filtering and wavelet analysis processing etc.
Some functional electrical stimulatos that lead 3, for according to the dynamic myoelectricity envelope shape command signal of described analog integration, stimulate the affected limb of strong side limbs offside to produce the mirror movements of equal proportion synchronous with equal proportion image current.By equal proportion image current, stimulate offside mirror image muscle to produce equal proportion synchronous, when Ipsilateral muscle contraction, both produced real mirror movements, make again Ipsilateral muscle obtain functional exercise, make the somesthetic sensibility sensors such as intramuscular tendon, muscle-spindle excited, participate in the sensation feedback regulation in nervus motorius loop and the reconstruction of reflex arc, better promote the rehabilitation of Ipsilateral nervus motorius function.
For better effects on surface electromyographic signal is processed, the present embodiment mirror movements neuromodulation system further comprises: processor 4, this processor 4 is connected between described bio-signals amplifier 1 and microcomputer controller 2, for described surface electromyogram signal being carried out to AD conversion, amplification, rectification, filtering and integrating circuit, processes.
The information such as activity sequential between the amplitude of the electromyographic signal on the bio-signals amplifier strong side limb muscle of 1 collection surface, waveform, activity time, intermittent time, each muscle group.Afterwards by collected 4 amplifications of information process processor, Filtering Processing, consider and remove the frequency irrelevant with signal, through over commutation and integrating circuit, signal is changed through AD, in mathematical processing methods such as the interior employing wavelet analysises of microcomputer controller 2, form the analog integration network signal consistent with strong side musculation, use sort signal as control instruction signal, the output of the functional electrical stimulato 3 of regulation and control respective channel, makes affected limb produce synchronous mirror motion.
In addition, for the collaborative cerebral cortex neurons that stimulates, the present embodiment mirror movements neuromodulation system further comprises micro-current DC constant current stimulator 5, this micro-current DC constant current stimulator 5 is connected with described microcomputer controller 2, the positive pole of micro-current DC constant current stimulator 5 connects the head position of the cortical representation of affected limb, increase irritability and the blood flow of Ipsilateral brain, negative pole connects the corresponding head surface of strong side, suppresses the inhibition of strong side hemisphere to Ipsilateral.For when periphery limbs produce mirror movements, micro-current DC electricity irritation of head is worked in coordination with stimulates cerebral cortex neurons, regulates and increase the irritability of Ipsilateral brain, jointly promotes the recovery of impaired cortex hormone function.
Because, bilateral brain is coordination and interinhibitive mutually to the control of motor function, after one-sided brain brain motor function damage, Ipsilateral cortex disappears to the inhibition of strong side brain, and strong lateral movement cortex strengthens the inhibitory action of Ipsilateral motor cortex, the normal excited function of recovery that is unfavorable for Ipsilateral brain injured nerve, therefore need to regulate and control the corticocerebral irritability of bilateral with micro-electric current, with cathodal current, suppress the inhibition of strong side brain to Ipsilateral, strengthen the corticocerebral irritability of Ipsilateral, have effect collaborative and increase curative effect with mirror movements treatment.
What the above-mentioned micro-current DC constant current stimulator 5 of the present embodiment was selected is high voltage operational amplifier and constant-current source circuit, and this instrument has the function stimulating through cranium direct electric current.The stimulating current of described micro-current DC constant current stimulator 5 is less than 5mA.
Described bio-signals amplifier 1 can adopt low noise high impedance instrument amplifier, and this instrument has various bioelectrical signals measuring abilities, can detect electrocardio, brain electricity and electromyogram signal.
What described microcomputer controller 2 was selected is ARM series monolithic, and this instrument has quick, high-precision mathematical operation function.
Above-mentioned microprocessor 4 can adopt analog integration electric stimulator with microcomputer controller 2, what this analog integration electric stimulator was selected is operational amplifier, through high-frequency diode arrangement, digital filtering, micro computer wavelet analysis, through peak value, detect and smoothing processing, obtain the surface electromyogram signal of real-time synchronization.This instrument has checking with EMG method, analysis and myoelectricity envelope signal abstraction function.
The myoelectricity bio signal of polylith muscle when the present embodiment is moved by the strong side limb function of multi-lead biological amplifier collection, by rectifying and wave-filtering and computer, be treated as analog integration myoelectricity envelope signal, as the command signal that stimulates the some respective muscle mirror movementses of offside, modulation multi-lead functional electric stimulation drives the mirror movements of affected limb respective muscle, because strong side cortex nervus motorius can produce the mutual inhibition to Ipsilateral brain motor region, with the anelectrode of micro-current DC constant current stimulator 5, stimulate Ipsilateral brain, negative electrode is placed in the scalp position of strong side brain motor region, reduce the inhibition of strong side brain to Ipsilateral brain, improve Ipsilateral cerebral nerve irritability.Brain mirror neuron active mechanism during this technical modelling human body study motion, excite mirror neuron movable, allow patient initiatively participate in, transfer bilateral brain simultaneously movable, be a kind of non-invasive neural Active Learning reconstruction technique, contribute to patient's injured nerve reconstruction and rehabilitation.
Below in conjunction with Fig. 2, the operation principle of the present embodiment is elaborated as follows:
During use, detecting electrode 11 and stimulating electrode 31 are attached to respectively to patient's strong side and the corresponding muscle of Ipsilateral position, when the strong side limbs of patient moving, 11 information of collecting strong side limb muscle surface electromyogram signal of detecting electrode of biological amplifier input, through amplifying, rectification, the processing of filtering and integrating circuit, again through the AD conversion of microcomputer controller 2 self, the Mathematical treatment such as digital filtering and wavelet analysis, produce the integration envelope electromyographic signal of strong pleural muscle group when functional activity, modulation is for the output of the functional electrical stimulato 3 of affected limb, in order to produce the mirror movements of affected limb.
With the micro-electric current below micro-current DC constant current stimulator 5 output 5mA, with positive polar stimulation Ipsilateral brain head movement district, negative pole stimulates strong side brain corresponding sports district simultaneously.When periphery limbs produce mirror movements, the collaborative cerebral cortex neurons that stimulates of micro-current DC electricity irritation of head, the irritability of adjusting and increase Ipsilateral brain, promotes the reply of impaired cortex hormone function jointly.
In addition, microcomputer controller 2 can also time delay trigger described functional electrical stimulato 3, makes the time delay of affected limb muscular irritation time synchronized, produces the phase alternation motion of strong side limbs and affected limb.
Particularly, the present invention can utilize the functional electric physiological activity of strong nervus lateralis muscle, control the motion of offside diseased muscles generation synchronous mirror, also can trigger by time delay, the asynchronous Coordinating Activity during as functional lock by the asynchronous stimulation Ipsilateral of signal sequence of strong each passage of side, simulation bilateral limbs suppress alternately, shrink in turn, as upper limb, the lower limb alternating movement in turn of walking, complete walking function.
Embodiment of the present invention mirror movements neuromodulation system, integrated application FES, tDCS technology and mirror movements neuron participate in the principle of motor control, utilize bio-signals amplifier 1, the functional electrical stimulato 3 that simulation myoelectricity integration envelope signal is controlled, micro-current DC constant current stimulator 5 is under the integration of microcomputer controller 2, integrated, utilizes strong side limbs to carry out the electromyographic signal of some muscle groups of functional activation, through amplifying, rectification, filtering, sampling and Mathematical treatment, produce the myoelectrical activity envelope signal of some functional activity muscle groups, and modulate and control some functional electric stimulations that lead with this, makes some muscle groups of the ill limbs of offside according to the activity intensity of strong pleural muscle electricity, Strength Changes, contraction time, intermittent time, the mirror image action that activity timing sequence generating is same, without mirror, patient can see and feel that synchronous mirror activity or the functional mirror image of bilateral limbs is movable, fully activates with transfer patient mirror image neural, sensory nerve, nervus motorius and motion drive idea, the nervus centraliss such as motor feedback, peripheral nervous reflex arc, participates in realizing brain function regulation and control and rebuilds, and promotes the plasticity of nerve synapse, promotes the rehabilitation of function of nervous system, thereby reaches the therapeutic effect of athletic rehabilitation.
The present invention is as a kind of innovative means of novel exercise therapy, simple, easy to learn, be easy to do, efficiently, safety, increased a kind of new Therapeutic Method to nervimotion rehabilitation.Simultaneously the present invention can also control programming by computer, makes the time delay of Ipsilateral muscular irritation time synchronized, produces the phase alternation of being good for side and affected limb and move, suppress being alternately synchronized with the movement and asynchronous movement of motion, mirror movements, coordination.
The foregoing is only the preferred embodiments of the present invention; not thereby limit the scope of the claims of the present invention; every equivalent structure or conversion of equivalent flow process that utilizes description of the present invention and accompanying drawing content to do; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.
Claims (9)
1. a mirror movements neuromodulation system, is characterized in that, comprising:
Some bio-signals amplifiers that lead, the information of the surface electromyogram signal while being good for side limb activity for gathering;
Microcomputer controller, for described surface electromyogram signal is processed, forms the dynamic myoelectricity envelope shape command signal of analog integration;
Some functional electrical stimulatos that lead, for according to the dynamic myoelectricity envelope shape command signal of described analog integration, stimulate the affected limb of strong side limbs offside to produce the mirror movements of equal proportion synchronous with equal proportion image current;
Micro-current DC constant current stimulator, be connected with described microcomputer controller, the positive pole of micro-current DC constant current stimulator connects the head position of the cortical representation of affected limb, negative pole connects the corresponding head surface of strong side, for when periphery limbs produce mirror movements, the collaborative cerebral cortex neurons that stimulates of micro-current DC electricity irritation of head, the irritability of adjusting and increase Ipsilateral brain, promotes the recovery of impaired cortex hormone function jointly.
2. mirror movements neuromodulation system according to claim 1, is characterized in that, described some bio-signals amplifiers that lead have detecting electrode, and described detecting electrode is attached to the respective muscle position of the strong side limbs of patient; Described some functional electrical stimulatos leading have stimulating electrode, and described stimulating electrode is attached to the corresponding muscle position of patient's affected limb.
3. mirror movements neuromodulation system according to claim 2, it is characterized in that, also comprise: processor, be connected between described bio-signals amplifier and microcomputer controller, for described surface electromyogram signal being carried out to AD conversion, amplification, rectification, filtering and integrating circuit, process.
4. mirror movements neuromodulation system according to claim 3, is characterized in that, the mode that described microcomputer controller is processed described surface electromyogram signal comprises: AD conversion, digital filtering and wavelet analysis are processed.
5. mirror movements neuromodulation system according to claim 4, is characterized in that, what described micro-current DC constant current stimulator was selected is high voltage operational amplifier and constant-current source circuit.
6. mirror movements neuromodulation system according to claim 5, is characterized in that, the stimulating current of described micro-current DC constant current stimulator is less than 5mA.
7. according to the mirror movements neuromodulation system described in any one in claim 1-6, it is characterized in that, described microcomputer controller also triggers described functional electrical stimulato for time delay, make the time delay of affected limb muscular irritation time synchronized, produce the phase alternation motion of strong side limbs and affected limb.
8. mirror movements neuromodulation system according to claim 7, is characterized in that, described bio-signals amplifier is low noise high impedance instrument amplifier; What described microcomputer controller was selected is ARM series monolithic.
9. mirror movements neuromodulation system according to claim 1, is characterized in that, it is one of following that the information of described surface electromyogram signal at least comprises: the activity sequential between the amplitude of electromyographic signal, waveform, activity time, intermittent time, each muscle group.
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Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103212156B (en) * | 2013-04-03 | 2015-10-28 | 重庆德领科技有限公司 | The autonomous instrument of hemiplegic patient based on body image theory |
| CN104383637B (en) * | 2014-12-09 | 2015-12-02 | 北京银河润泰科技有限公司 | A kind of training auxiliary facilities and training householder method |
| CN104888346B (en) * | 2014-12-21 | 2020-10-13 | 徐志强 | Method and device for performing nerve stimulation on coma brain |
| EP3269344B1 (en) * | 2015-03-13 | 2022-08-10 | Tokai University Educational System | Spinal cord stimulation device for gait training |
| CN105056396A (en) * | 2015-09-09 | 2015-11-18 | 上海诺诚电气股份有限公司 | Mirror evaluation training low-frequency electric stimulation rehabilitation system and use method |
| CN105148404B (en) * | 2015-09-16 | 2018-08-31 | 燕铁斌 | Electro photoluminescence training system and training method based on the triggering of strong side limbs electromyography signal |
| CN106176134A (en) * | 2016-07-12 | 2016-12-07 | 王春宝 | A kind of method and system of autonomous training |
| US10799152B2 (en) * | 2016-08-11 | 2020-10-13 | Medtronic Xomed, Inc. | System and method for motion detection and accounting |
| CN106422203B (en) * | 2016-11-23 | 2018-11-16 | 佛山科学技术学院 | A kind of rehabilitation training of upper limbs method of the multi-modal feedback of photoelectricity based on mirror image therapy |
| CN106861037A (en) * | 2017-01-03 | 2017-06-20 | 江苏德长医疗科技有限公司 | Neural network reconstruction training method under wireless wearable functional electric stimulation system auxiliary |
| CN107041748B (en) * | 2017-01-26 | 2018-11-06 | 杨鹏 | One kind triggering Magnetotherapeutic apparatus for backbone reduction system electrocardio |
| CN107212480A (en) * | 2017-05-16 | 2017-09-29 | 广东乐源数字技术有限公司 | A kind of intelligent clothing and exercise guidance system for monitoring motion respiratory rate |
| CN107156943A (en) * | 2017-05-16 | 2017-09-15 | 广东乐源数字技术有限公司 | The intelligent clothing and its system of a kind of motion monitoring |
| CN107398011B (en) * | 2017-08-18 | 2018-11-13 | 广东美的安川服务机器人有限公司 | A kind of biostimulation feedback device |
| CN108543216A (en) * | 2018-01-26 | 2018-09-18 | 南京航空航天大学 | A kind of hand function reconstructing device and its implementation based on master ＆ slave control |
| CN108939436B (en) * | 2018-08-01 | 2020-03-24 | 深圳睿瀚医疗科技有限公司 | Active lower limb training system with healthy side and sick side synergistic function and operation method thereof |
| CN109173052B (en) * | 2018-10-10 | 2021-06-29 | 北京理工大学 | Nerve stimulation rehabilitation system and nerve stimulation method based on motor intention |
| CN109901711B (en) * | 2019-01-29 | 2020-06-19 | 西安交通大学 | Asynchronous real-time brain control method driven by weak myoelectricity artifact micro-expression electroencephalogram signals |
| CN110136800A (en) * | 2019-05-08 | 2019-08-16 | 博睿康科技（常州）股份有限公司 | A kind of initiative rehabilitation training system that combination is stimulated through cranium electric current |
| CN110074947A (en) * | 2019-05-16 | 2019-08-02 | 东南大学 | A kind of myoelectricity bridging method and system for realizing hemiplegia lower limb gait action control |
| CN113041089A (en) * | 2019-12-26 | 2021-06-29 | 上海神泰医疗科技有限公司 | Mirror image treatment device and mirror image treatment system |
| CN111513713B (en) * | 2020-04-30 | 2022-01-14 | 中山大学附属第一医院 | Method for evaluating body muscle cerebral cortex movement representative region and application thereof |
| CN113058157B (en) * | 2021-02-25 | 2022-01-18 | 国家康复辅具研究中心 | Feedback type functional electrical stimulation system with multi-signal fusion |
| TWI763382B (en) * | 2021-03-18 | 2022-05-01 | 宏碁股份有限公司 | Electronic device and method for determining the intensity of low-frequency current |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1041873A (en) * | 1988-10-19 | 1990-05-09 | 中国医学科学院生物医学工程研究所 | The checkout gear of electric stimulus inducing myoelectric potential |
| CN1015510B (en) * | 1988-10-19 | 1992-02-19 | 中国医学科学院生物医学工程研究所 | Physiotherapy device for hemiplegia patient |
| US8929991B2 (en) * | 2005-10-19 | 2015-01-06 | Advanced Neuromodulation Systems, Inc. | Methods for establishing parameters for neural stimulation, including via performance of working memory tasks, and associated kits |
| US20080139870A1 (en) * | 2006-12-12 | 2008-06-12 | Northstar Neuroscience, Inc. | Systems and methods for treating patient hypertonicity |
| DE102008043973B4 (en) * | 2008-11-21 | 2011-12-01 | Burkhard Brocke | Device for transcranial neurostimulation |
| MX2012010841A (en) * | 2010-03-22 | 2013-01-29 | Univ City New York Res Found | Charge-enhanced neural electric stimulation system. |
| CN102580235A (en) * | 2012-02-24 | 2012-07-18 | 江苏苏云医疗器材有限公司 | Transcranial direct current stimulation instrument |
-
2012
- 2012-09-25 CN CN201210361260.2A patent/CN102886102B/en active Active
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