CN201049348Y - Cleaning head for perforated plate - Google Patents
Cleaning head for perforated plate Download PDFInfo
- Publication number
- CN201049348Y CN201049348Y CNU2007200716093U CN200720071609U CN201049348Y CN 201049348 Y CN201049348 Y CN 201049348Y CN U2007200716093 U CNU2007200716093 U CN U2007200716093U CN 200720071609 U CN200720071609 U CN 200720071609U CN 201049348 Y CN201049348 Y CN 201049348Y
- Authority
- CN
- China
- Prior art keywords
- water
- water injection
- side plate
- water outlet
- injection pipe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Landscapes
- Cleaning By Liquid Or Steam (AREA)
Abstract
The utility model discloses a cleaning head for a perforated plate and relates to a cleaning apparatus for a perforated plate and a perforated bio-chip. The utility model comprises a row of water suction pipes, a row of water injection pipes, a water injection interface, a water outlet interface, a main body part, a side plate, a side plate rubber mat, a perforated partition, as well as a water injection cavity, a water outlet cavity, a water injection buffer cavity and a water outlet buffer cavity, all of which are enclosed and partitioned by the main body part, the side plate rubber mat and the perforated partition. The water injection interface is connected to the water injection pipe through the water injection buffer cavity, the holes in the perforated partition as well as the water injection cavity; the water outlet interface is connected to the water suction pipe through the water outlet buffer cavity, the holes in the perforated partition as well as the water outlet cavity. The side plate and the side plate rubber mat are fixed on the main body part in a convenient detachment way through bolts or snap grooves on both sides of the main body part so as to clean and maintain the insides of various cavities, the partition and the insides of the pipes. The utility model has good uniformity, simple cleaning and maintenance as well as use, flexible cleaning way, is applicable to various experiments with different scales, and has good maneuverability.
Description
Technical field
The utility model relates to the porous plate that uses in medical science, biology, the chemical analysis and the cleaning equipment of multiporous biological chip, exactly, is the key component in a kind of automatic enzyme mark washing facility or the biochip washing facility.
Background technology
Enzyme linked immunosorbent assay (ELISA) (ELISA) is a kind of important technology in the immunity inspection, and along with development of biology, biological chip testing technology also more and more is applied to immunity inspection.And in ELISA experiment or biochip test process, accurately and completely washing is to guarantee its result key technology accurately and reliably, rely on washing to remove antigen (or antibody) other material in addition that combines with insolubilized antibody (or antigen) specificity in the tested sample because in ELISA experiment and the biochip test process all be, comprise: the enzyme labeling thing of separated free in liquid, the material that remains in the plate hole or do not combine on the film with solid phase antigen (or antibody), and in course of reaction the interference adsorbate of non-specific binding.The quality of washing is directly connected to the success or failure of experiment, adopts accurately and completely mode of washing, can make the signal to noise ratio of ELISA experiment and biochip test improve several times.
The existing cleaning head of washing on the plate machine, be divided into water filling head and Water outlet more and be divided into two groups, one group of water filling head is responsible for injecting washing lotion in porous plate, and another group Water outlet is responsible for the soiling solution in the respective aperture is sopped up, also have recently the cleaning head of water filling head and Water outlet design, even water filling head and Water outlet are done concentric design in one.But all there is following defective in these cleaning heads:
1. suction head and water filling head branch are arranged, and this washes the plate machine with regard to inevitable requirement these two groups of cleaning heads are respectively installed on one group of manipulator, and controls respectively, complex structure not only, and the manufacturing cost of washing the plate machine also increases relatively.
2. the hole count of the quantity of suction hose and water injection pipe and porous plate equates, therefore can only put in order the whole plate ground of plate and clean, and can only clean the fixedly porous plate of hole count, and cleaning way is dumb, is not suitable for some small-scale experiments.
3. the length of suction hose and water injection pipe is identical, only cause waiting after suction hose sucking-off soiling solution and manipulator from ELISA Plate be lifted to certain height with cleaning head, water injection pipe could inject washing lotion in corresponding hole, caused waste of time like this, and the efficient of washing plate is lower.
4. suction hose and water injection pipe are directly connected to water outlet interface and water filling interface by a pipeline respectively, owing to do not consider fluid pressure performance inhomogeneous in pipeline, cause the homogeneity of suction pressure, water absorption, water injection pressure, water injection rate etc. of its each suction hose and water injection pipe poor.
5. suction hose and water injection pipe and cleaning head cavity content are easily stopped up by liquid crystalization and other dirt, and easy to clean is not safeguarded, causes bringing in its use bigger inhomogeneity.
The purpose of this utility model is to be at the problems referred to above, and a kind of cleaning head is provided, and has better homogeneity, and cleaning way is flexible, and applicability is stronger, and clean and maintenance is used more convenient.
Summary of the invention
The purpose of this utility model is achieved in that a kind of cleaning head, the water-injecting cavity, water chamber, water filling cushion chamber, the water outlet cushion chamber that include row's suction hose, row's water injection pipe, water filling interface, water outlet interface, main part, side plate, side plate rubber cushion, porous barrier and contained and be separated by main part, side plate rubber cushion and porous barrier.
Described suction hose and water injection pipe certain distance are at interval lined up two rows, and the quantity of suction hose and water injection pipe all can be 6,8,12; Each suction hose length is identical, and each water injection pipe length is identical, but the length of suction hose and water injection pipe is different, and suction hose is longer than water injection pipe, and suction hose is used to draw the soiling solution that detects in the hole, and water injection pipe then is used for injecting washing lotion in corresponding hole.
As one of improvement of the present utility model, include 2-6 porous barrier in the cavity of described cleaning head main part, the cavity of main part is divided into four chambers such as water-injecting cavity, water chamber, water outlet cushion chamber, water filling cushion chamber, water-injecting cavity is connected to the water filling cushion chamber by a plurality of holes on the porous barrier, and water chamber is connected to the water outlet cushion chamber by a plurality of holes on another porous barrier.The water filling interface is connected to water injection pipe by hole in water filling cushion chamber, the porous barrier and water-injecting cavity, the water outlet interface is connected to suction hose by hole in water outlet cushion chamber, the porous barrier and water chamber, and cuts off mutually by main part and side plate rubber cushion between water filling interface, water filling cushion chamber, water-injecting cavity, water injection pipe and water outlet interface, water outlet cushion chamber, water chamber, the suction hose.
As another improvements of the present utility model, described side plate and the side plate rubber cushion draw-in groove by screw or main part both sides is can mode for convenience detach being fixed on the main part, both sides are sealed, and separately water-injecting cavity, water chamber, water outlet cushion chamber, water filling cushion chamber, and side plate and side plate rubber cushion also can take out from main part, so that in each cavity, carry out clean and maintenance in dividing plate and the pipeline.
It is significant that the utility model is compared effect with prior art:
1. the utility model provides a kind of cleaning head that has a plurality of water injection pipes and suction hose simultaneously, not only simplifies the structure, and has also reduced the cost of washing the plate machine.
2. the utility model provides the cleaning head that a kind of row's water injection pipe and row's suction hose are formed, not only reduced volume, and only clean a row at every turn, the user can select the hole count of cleaning and the mode of cleaning according to the needs of oneself like this, needn't put in order cleaning of plate at every turn, flexibility is higher, but also can be used for the more porous plate and the biochip of polytypic, and applicability is stronger.
3. the utility model provides the cleaning head of a kind of water injection pipe and suction hose different length, when long suction hose was drawn soiling solution, short water injection pipe can inject washing lotion in the corresponding in the past hole, can form mobile washing lotion like this, strengthen clean result, reduce detection background; And suction hose when promoting water injection pipe can also carry out the injection of washing lotion simultaneously, avoided waste of time in the cleaning head lifting process, improved the efficient of washing.
4. as one of improvement of the present utility model, include 2-6 porous barrier in the cavity of described cleaning head main part, the cavity of main part is divided into water-injecting cavity, the water filling cushion chamber, water chamber and water outlet cushion chamber, the water filling cushion chamber, buffering that porous barrier and water-injecting cavity etc. are multi-level and homogenization, make the water injection pressure and the water injection rate of each water injection pipe more even, and the water outlet cushion chamber, buffering that porous barrier and water chamber etc. are multi-level and homogenization, also make the imbibition pressure and the liquid absorption of each suction hose more even, make that like this washing homogeneity of porous plate or biochip is better, CV (Coefficent of Variation, the coefficient of variation) is littler.
5. as another improvements of the present utility model, described side plate and the side plate rubber cushion draw-in groove by screw or main part both sides is can mode for convenience detach being fixed on the main part, can split out side plate and side plate rubber cushion in case of necessity, to in each cavity, carry out clean and maintenance in dividing plate and the pipeline, not only make the easy clean and maintenance in inside of cleaning head, and improved the stability of its use, guaranteed the homogeneity that ELISA Plate and biochip clean.
Description of drawings
Fig. 1 is the three-dimensional structure schematic diagram of an embodiment of the utility model.
Front-view schematic diagram when Fig. 2 removes a side side plate and side plate rubber cushion for embodiment of the utility model.
The specific embodiment
Below in conjunction with accompanying drawing, and the specific embodiment when the quantity of suction hose (12) and water injection pipe (11) is 8 further specifies the utility model:
As depicted in figs. 1 and 2, a kind of cleaning head described in the utility model, (4) four chambers of water-injecting cavity (1), water chamber (2), water filling cushion chamber (5), water outlet cushion chamber that include row's suction hose (12), row's water injection pipe (11), a water filling interface (8), a water outlet interface (9), main part (10), two side plates (6), two side plate rubber cushions (7), two porous barriers (3) and contain and be separated by main part (10), side plate rubber cushion (7) and porous barrier (3).
Described suction hose (12) and water injection pipe (11) certain distance are at interval lined up two rows, and this suction hose (12) and water injection pipe (11) spacing are less than half of the pitch of holes of porous plate or multiporous biological chip.Each suction hose (12) length is identical, each water injection pipe (11) length is identical, but suction hose (12) is different with the length of water injection pipe (11), suction hose (12) will be grown than the length of water injection pipe (11), suction hose (12) is used to draw the soiling solution that detects in the hole, and water injection pipe (11) then is used for injecting washing lotion in corresponding hole.When the end face of long suction hose (12) when the hole inner bottom part carries out imbibition, the end face of short water injection pipe (11) then can be exposed in the hole on the liquid level, washing lotion is injected in this hole, and when cleaning head lifted, water injection pipe (11) still injected washing lotion in this hole in the past, had saved the time of injecting washing lotion greatly, improved efficient, and in this hole, inject washing lotion suction decontamination liquid simultaneously, and it is more thorough that the washing lotion that formation is flowed can be cleaned the interference of non-specific binding, and detection background is lower.
As one of improvement of the present utility model, include 2 porous barriers (3) in the cavity of described cleaning head main part (10), the cavity of main part (10) is divided into water-injecting cavity (1), water chamber (2), water outlet cushion chamber (4), (5) four chambers of water filling cushion chamber, water-injecting cavity (1) is connected to water filling cushion chamber (5) by a plurality of holes on the porous barrier (3), and water chamber (2) is connected to water outlet cushion chamber (4) by a plurality of holes on another porous barrier (3).Water filling interface (8) is by water filling cushion chamber (5), hole in the porous barrier (3) and water-injecting cavity (1) are connected to water injection pipe (11), water outlet interface (9) is by water outlet cushion chamber (4), hole in the porous barrier (3) and water chamber (2) are connected to suction hose (12), and water filling interface (8), water filling cushion chamber (5), water-injecting cavity (1), pipe-line system that water injection pipe (11) is linked to be and water outlet interface (9), water outlet cushion chamber (4), water chamber (2), cut off mutually by main part (10) and side plate rubber cushion (7) between the pipe-line system that suction hose (12) is linked to be.Washing lotion enters the water filling cushion chamber (5) of cleaning head from water filling interface (8), through once entering water-injecting cavity (1) by the hole on the porous barrier (3) after the buffering, through being injected in the detection hole of porous plate or biochip by water injection pipe (11) after the buffering again; Soiling solution enters the water chamber (2) of cleaning head from suction hose (12), enters water outlet cushion chamber (4) through buffering back once by the hole on the porous barrier (3), through after the buffering again by water outlet interface (9) outflow cleaning head.Multi-level buffering and homogenization also make water injection pressure and water injection rate, imbibition pressure and liquid absorption more even, make that like this washing homogeneity of porous plate or biochip is better, and CV is littler.
As another improvements of the present utility model, draw-in groove has all been designed in described cleaning head main part (10) both sides, side plate (6) and side plate rubber cushion (7) have been installed in the draw-in groove, both sides are sealed, and separately water-injecting cavity (1), water chamber (2), water outlet cushion chamber (4), water filling cushion chamber (5), and side plate (6) and side plate rubber cushion (7) also can take out from the draw-in groove of main part (10), so that to carrying out clean and maintenance in (1) (2) (4) (5), porous barrier (3) and pipeline (11), (12) in each cavity.Not only make the easy clean and maintenance in inside of cleaning head, and improved the stability of its use, guaranteed the homogeneity that ELISA Plate and biochip clean.
Should be understood that those skilled in the art can do various increases and decreases or modification to the utility model after reading foregoing of the present utility model, these equivalent form of values fall within the application's appended claims institute restricted portion equally.
Claims (5)
1. the cleaning head of a porous plate, include row's suction hose (12), row water injection pipe (11), a water filling interface (8), water outlet interface (9), main part (10), side plate (6), side plate rubber cushion (7), porous barrier (3), and the water-injecting cavity (1), water chamber (2), water filling cushion chamber (5), the water outlet cushion chamber (4) that contain and be separated by main part (10), side plate rubber cushion (7) and porous barrier (3); It is characterized in that, water filling interface (8) is connected to water injection pipe (11) by hole in water filling cushion chamber (5), the porous barrier (3) and water-injecting cavity (1), water outlet interface (9) is connected to suction hose (12) by hole in water outlet cushion chamber (4), the porous barrier (3) and water chamber (2), and between water filling interface (8), water filling cushion chamber (5), water-injecting cavity (1), water injection pipe (11) and water outlet interface (9), water outlet cushion chamber (4), water chamber (2), the suction hose (12) by main part (10) and side plate rubber cushion (7) partition mutually.
2. the cleaning head of a kind of porous plate according to claim 1 is characterized in that, described side plate (6) and side plate rubber cushion (7) draw-in groove by screw or main part (10) both sides is can mode for convenience detach being fixed on the main part (10).
3. the cleaning head of a kind of orifice plate according to claim 1 is characterized in that, the quantity of described suction hose (12) and water injection pipe (11) all can be 6,8,12.
4. the cleaning head of a kind of porous plate according to claim 1 is characterized in that, described each suction hose length is identical, and each water injection pipe length is identical, but the length of suction hose and water injection pipe is different.
5. the cleaning head of a kind of porous plate according to claim 1 is characterized in that, the quantity of described porous barrier (3) can be 2-6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200716093U CN201049348Y (en) | 2007-06-26 | 2007-06-26 | Cleaning head for perforated plate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200716093U CN201049348Y (en) | 2007-06-26 | 2007-06-26 | Cleaning head for perforated plate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201049348Y true CN201049348Y (en) | 2008-04-23 |
Family
ID=39335829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007200716093U Expired - Lifetime CN201049348Y (en) | 2007-06-26 | 2007-06-26 | Cleaning head for perforated plate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201049348Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101332459B (en) * | 2007-06-26 | 2011-11-30 | 上海裕隆生物科技有限公司 | Cleaning head of porous sheet |
| CN103372547A (en) * | 2012-04-19 | 2013-10-30 | 生物梅里埃公司 | Method for cleaning test sample well, and cleaning head using said method |
| CN114847148A (en) * | 2022-03-14 | 2022-08-05 | 福建省中科生物股份有限公司 | Sponge water injection device for planting cup |
-
2007
- 2007-06-26 CN CNU2007200716093U patent/CN201049348Y/en not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101332459B (en) * | 2007-06-26 | 2011-11-30 | 上海裕隆生物科技有限公司 | Cleaning head of porous sheet |
| CN103372547A (en) * | 2012-04-19 | 2013-10-30 | 生物梅里埃公司 | Method for cleaning test sample well, and cleaning head using said method |
| CN103372547B (en) * | 2012-04-19 | 2017-04-26 | 生物梅里埃公司 | Method for cleaning test sample well, and cleaning head using said method |
| US10144039B2 (en) | 2012-04-19 | 2018-12-04 | Biomerieux | Method for cleaning test sample wells, and cleaning head using said method |
| CN114847148A (en) * | 2022-03-14 | 2022-08-05 | 福建省中科生物股份有限公司 | Sponge water injection device for planting cup |
| CN114847148B (en) * | 2022-03-14 | 2023-12-29 | 福建省中科生物股份有限公司 | Field planting cup sponge water injection device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101332459B (en) | Cleaning head of porous sheet | |
| CN201049348Y (en) | Cleaning head for perforated plate | |
| CN208038442U (en) | A kind of liquid channel system of gene sequencer | |
| CN106734002A (en) | One kind is for genetic engineering experiment test tube cleaning and sterilizing integrated apparatus | |
| CN108709880A (en) | Reusable high throughput SERS micro-fluidic chips and its application | |
| CN103230897A (en) | Cleaning device and cleaning method | |
| CN208395160U (en) | A kind of device extracting DNA quickly through transfer magnetic bead | |
| CN102921481A (en) | Microfluid array device | |
| CN202741366U (en) | Needle washing groove | |
| CN204564702U (en) | A kind of sample injection bottle cleaning device of easy controlled cleaning agent volume | |
| CN103240237A (en) | Ultrasonic vibration cleaning tank and cleaning method utilizing same | |
| CN203265144U (en) | Washing device | |
| CN106959332B (en) | The automatic fine sampling device and its control method of electrophoresis detection instrument | |
| CN201207047Y (en) | Test device for static absorption ability of amorphous floc to water body pollutant | |
| CN202021171U (en) | Automatic cleaning system used for flowing type semi-automatic biochemical analyzer | |
| CN201955342U (en) | Fluorescence detection kit for asialoglycoprotein receptor (ASGPR) | |
| CN203265145U (en) | Ultrasonic vibration rinse tank | |
| CN203881769U (en) | Elisa plate sample injector | |
| CN204874530U (en) | Unimolecule order -checking chip | |
| CN210936307U (en) | Nuclear magnetic sample tube cleaning device | |
| CN201654032U (en) | Liquid feeding and drainage system of biosensing analyzer | |
| CN204752719U (en) | Cell fluid experiment mixed flow pipe | |
| CN205313433U (en) | Antibody purification device | |
| CN208894701U (en) | A kind of board-washing machine compatibility cleaning head | |
| CN215415479U (en) | A walk glue albumen and transfer neat frame for immunoblotting experiment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20080423 Effective date of abandoning: 20070626 |