CN1973876A - Chinese medicine for treating kidney deficiency and its prpen - Google Patents
Chinese medicine for treating kidney deficiency and its prpen Download PDFInfo
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- CN1973876A CN1973876A CNA2006101638034A CN200610163803A CN1973876A CN 1973876 A CN1973876 A CN 1973876A CN A2006101638034 A CNA2006101638034 A CN A2006101638034A CN 200610163803 A CN200610163803 A CN 200610163803A CN 1973876 A CN1973876 A CN 1973876A
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Abstract
The present invention relates to one kind of Chinese medicine soft capsule for treating kidney deficiency and its preparation process. The Chinese medicine in the capsule is prepared with ten kinds of Chinese medicinal materials, including ginseng, desert cistanche, prepared rhizome of rehmannia, epimedium, wolfberry fruit, etc in certain weight proportion. The Chinese medicine soft capsule may capsulate the Chinese medicine extractum or the Chinese medicine extractum powder. The Chinese medicine soft capsule has the features of regulating Yin and Yang, no hormone content, protecting liver and kidney, high bioavailability, etc. It is used in treating various diseases caused by kidney deficiency, and has obvious curative effect.
Description
Technical field
The present invention relates to field of pharmaceutical technology, traditional tonic medicine that specifically a kind of treatment is suffered from a deficiency of the kidney and preparation method thereof.
Background technology
" kidney " of the traditional Chinese medical science and the kidney on the doctor trained in Western medicine anatomy are diverse, and the kidney of doctor trained in Western medicine is a pair of organ on the anatomy, and its major function is to filter the metabolite of draining body, keeps body water liquid, electrolytical balance, the blood volume of remaining valid." kidney " of the traditional Chinese medical science is not a concrete histoorgan, but the system that integrates out according to certain function, and the traditional Chinese medical science is thought " kidney storing essence, main bone is given birth to marrow, main water liquid, main improving inspiration by invigorating kidney-QI is had one's ideas straightened out in ear and two the moon ".And " kidney storing essence ", be again the prerequisite and the basis of all functional activities of the traditional Chinese medical science " kidney ", its function is equivalent to the function of skeleton in urinary system, reproductive system, nervous system, hormonal system, hemopoietic system and the motor system of doctor trained in Western medicine or the like, with " essence " is tie, utilization traditional Chinese medical science yin-yang and five elements, organic conception theory are organically got up these interconnections, therefore, " kidney " of the traditional Chinese medical science is the kidney on the functional meaning, be the comprehensive four diagnostic methods (hope, hear, ask, cut) data, on material base, discern according to the traditional Chinese medical science " dialectical " theory.Therefore, " kidney " of the traditional Chinese medical science has omnibearing regulatory function to human body, and the major physiological function has several aspects: improve immunity, promote growth, growth and the reproduction of body, regulate the metabolism and the physiological function activity of body.
Suffer from a deficiency of the kidney and show as: lethargy, soreness of waist lumbago, be short of physical strength, many or the urine of poor sleep (comprising insomnia, dreaminess, drowsiness), hypoimmunity, sexual hypofunction, seminal emission, urine amount as fat, have a dizzy spell, tinnitus, deafness, xerostomia, night sweat, low grade fever, flushed cheeks, feverish sensation in the palms and soles etc.
The symptom of suffering from a deficiency of the kidney is utilized modern instrument to detect and is often come to nothing, and Western medicine is also felt simply helpless to its treatment.No matter be all big without comparison breakthrough of formula components various aspects, can not satisfy patient's demand from traditional Chinese medical science mechanism, dosage form or the medicine of institute's foundation.
Summary of the invention
The objective of the invention is for specially at the symptom of suffering from a deficiency of the kidney, a kind of new benefiting action that has is provided, can effectively treat the traditional tonic medicine of the various symptoms of suffering from a deficiency of the kidney, the present invention also provides this preparation method of Chinese medicine.
Technical scheme of the present invention is achieved in that
The weight portion raw material of Chinese medicine preparation is: Radix Ginseng 12～18, Herba Cistanches 12～18, Radix Rehmanniae Preparata 12～18, Herba Epimedii 6～12, Fructus Lycii 12～18, Semen Litchi 4～9, Semen Astragali Complanati 6～12, Flos Caryophylli 6～12, Lignum Aquilariae Resinatum 1～5, Radix Polygalae 1～5.
The preferred weight percent raw material of Chinese medicine preparation is: Radix Ginseng 14～16, Herba Cistanches 14～16, Radix Rehmanniae Preparata 14～16, Herba Epimedii 8～10, Fructus Lycii 14～16, Semen Litchi 6～8, Semen Astragali Complanati 8～10, Flos Caryophylli 8～10, Lignum Aquilariae Resinatum 1～3, Radix Polygalae 1～3.
Preparation method of Chinese medicine of the present invention is: (make by medicine capsule heartwood material and capsule casing material two parts and form soft capsule)
1., seven flavor Chinese medicines such as Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain the medicinal liquid thick paste;
2., Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately obtain 200～300 purpose fine powders, mixing obtains mixed powder;
3., with the thick paste that makes and Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum mixed powder, join in proportion in the oil-based solvent, behind the mixing, make its evenly be suspended in the solvent capsule psychological treatment liquid, again capsule psychological treatment liquid and softgel shell are pressed into soft capsule at 25～28 ℃ of enclose.
4., after drying, packing is made patent medicine.
Perhaps preparation by the following method:
1., after Radix Ginseng decocts with water, filter and obtain filtrate, again filtrate is condensed into thick paste;
2., Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae seven flavors add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain thick paste;
3., with step 1., two kinds of thick pastes 2. obtaining mix, dry, pulverize, make powder;
4., Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately are made powder;
5., 3., 4. two kinds of powder mixes are even, cross the 80-120 mesh sieve, as capsule heartwood material, the sterilization back adds solvent, mixing, fill, is pressed into soft capsule with step;
6., after drying, packing is made patent medicine.
In the above-described preparation method of Chinese medicine, oil-based solvent is one or more in liquid polyethylene glycol, isopropyl alcohol, tween 80, glycerol, propylene glycol, the vegetable oil.
Softgel shell is made up of gelatin and glycerol, and the weight proportion of gelatin and glycerol is 10: 3.15～10: 3.35.
In the prescription of the present invention, medicines such as Radix Ginseng, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Herba Cistanches have immunoregulatory effect through modern medicine study.Both can benefiting vital QI and blood by full side's compatibility, directly strengthen and defend airway dysfunction, again can the replenishing essence the kidney invigorating, make that yang-energy fills Sheng in the kidney, yang-energy is defend gas basic in the kidney, and kidney qi is filled Sheng Zewei gas and is also filled Sheng, and the ability of resisting exopathogen also strengthens.Working along both lines in two aspects, brings out the best in each other, and makes medicine have more good effect in treatment and epidemic prevention power aspect low.Use the Radix Ginseng replenishing QI and blood, make kidney get the big benefit of Radix Ginseng and vital essence is more prosperous; Radix Rehmanniae Preparata, Fructus Lycii life essence-filling, marrow-benefitting, the blood-tonifying kidney-nourishing of big nourishing YIN essence; Herba Epimedii, Herba Cistanches benefit vital essence, fonifying life-gate fire be with YIN and YANG balance regulating, with specially control let out essence, consumptive disease with lumbago Semen Astragali Complanati with controlling nocturnal emission with astringent drugs gas, invigorating the liver and kidney, bright binocular; In Lignum Aquilariae Resinatum kidney tonifying essence, logical heart kidney, the dormancy of sleeping peacefully, the accent of being amusing; Flos Caryophylli, Semen Litchi depressed liver-energy dispersing and QI regulating, warming spleen and stomach for dispelling cold, the Radix Polygalae mind tranquilizing and the heart calming.Comprehensive full side has YIN and YANG balance regulating, and QI and blood is ruled together, and is not dry oiliness, do not contain hormone, do not hinder the intestines and stomach, protects the liver characteristics such as protecting kidney.
The soft capsule of making by prescription of the present invention is better than other dosage forms on dosage form, nurse one's health syndrome of deficiency of both yin and yang of kidney on prescription comprehensively, is applicable to the deficiency of both YIN and YANG clinical symptoms due to suffering from a deficiency of the kidney.
Clinical test results shows that the Chinese patent medicine soft capsule of being made by above prescription all has significant therapeutic effect to deficiency of the kidney yin and the insufficiency of kidney-YANG that various factors causes.(be grown up 18～36g/ days in certain dosage, 7 days courses of treatment) time, being 87.1% for the treatment effective percentage of the induced insomnia because of suffering from a deficiency of the kidney, is 93.3% to the treatment effective percentage because of the soreness of waist due to suffering from a deficiency of the kidney, and can treat sexual impotence, premature ejaculation, significant prolongation male's sex time.
The tonification soft capsule that makes with the present invention for suffer from a deficiency of the kidney, the curative effect (each 1.5～2 grams, were taken 15 continuously at every day 3 times) of aspects such as the soreness of waist, insomnia, sexual function improvement sees the following form:
| Symptom | The test number | Cure number | Obviously improve | Improvement is arranged | Invalid |
| Tired weak | 157 | 89 | 53 | 13 | 2 |
| Following waist and knee pain | 198 | 87 | 64 | 44 | 3 |
| Dizzy | 201 | 81 | 72 | 38 | 10 |
| Tinnitus | 172 | 52 | 64 | 42 | 13 |
| Inappetence | 81 | 26 | 34 | 15 | 6 |
| Insomnia and dreamful sleep | 112 | 35 | 43 | 23 | 11 |
| Hyposexuality | 212 | 58 | 101 | 43 | 10 |
| Premature ejaculation | 81 | 26 | 37 | 13 | 0 |
| Femal sexual function is low | 67 | 10 | 30 | 27 | |
| Sum | 1281 | 464 | 498 | 259 | 55 |
| Total effective rate | 95.1％ | ||||
The specific embodiment
Embodiment one:
Get raw material of Chinese medicine (unit: restrain):
Radix Ginseng 180, Herba Cistanches 120, Radix Rehmanniae Preparata 120, Herba Epimedii 60, Fructus Lycii 180, Semen Litchi 90, Semen Astragali Complanati 120, Flos Caryophylli 60, Lignum Aquilariae Resinatum 50, Radix Polygalae 20.
Preparation method:
1., Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae seven flavors add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain the medicinal liquid thick paste;
2., Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately become fine powder, can obtain 200 purpose fine powders through micropowder after broken, mixing obtains mixed powder.
3., the thick paste that makes and Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum mixed powder are mixed mixture, again mixture is joined in the propylene glycol solvent, press mixture: the part by weight of propylene glycol=1: 1 adds, it evenly is suspended in becomes capsule psychological treatment liquid in the solvent, again the capsule psychological treatment liquid that makes is pressed into soft capsule with softgel shell at 25～28 ℃ of enclose.
4., after drying, packing is made patent medicine.
Embodiment two:
Get raw material of Chinese medicine (unit: restrain):
Radix Ginseng 120, Herba Cistanches 180, Radix Rehmanniae Preparata 180, Herba Epimedii 120, Fructus Lycii 120, Semen Litchi 40, Semen Astragali Complanati 60, Flos Caryophylli 120, Lignum Aquilariae Resinatum 50, Radix Polygalae 10.
Preparation method:
1., Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae seven flavors add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain the medicinal liquid thick paste;
2., Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately become fine powder, can obtain 300 purpose fine powders through micropowder after broken, mixing obtains mixed powder.
3., the thick paste that makes and Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum mixed powder are mixed mixture, again mixture is joined in the tween 80, press mixture: the part by weight of tween 80=1: 2 adds, it evenly is suspended in becomes capsule psychological treatment liquid in the solvent, again the capsule psychological treatment liquid that makes is pressed into soft capsule with softgel shell at 25～28 ℃ of enclose.
4., after drying, packing is made patent medicine.
Embodiment three:
Get raw material of Chinese medicine (unit: restrain):
Radix Ginseng 150, Herba Cistanches 150, Radix Rehmanniae Preparata 150, Herba Epimedii 100, Fructus Lycii 150, Semen Litchi 60, Semen Astragali Complanati 100, Flos Caryophylli 100, Lignum Aquilariae Resinatum 20, Radix Polygalae 20.
Preparation method:
1., after Radix Ginseng decocts with water, filter and obtain filtrate, again filtrate is condensed into thick paste;
2., Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae seven flavors add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain thick paste;
3., with above-mentioned 1., 2. two kinds of thick pastes obtaining of step mix, dry, pulverize, make powder;
4., Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately are made powder;
5., will be 3., 4. two kinds of powder mixes in the step are even, cross the 80-120 mesh sieve, as capsule heartwood material mixed powder, the sterilization back adds Oleum Arachidis hypogaeae semen, press mixed powder: the weight ratio of Oleum Arachidis hypogaeae semen=1: 1 is mixed mixing, encapsulates, and is pressed into soft capsule;
6., after drying, packing is made patent medicine.
Embodiment four:
Get raw material of Chinese medicine (unit: restrain):
Radix Ginseng 160, Herba Cistanches 140, Radix Rehmanniae Preparata 140, Herba Epimedii 90, Fructus Lycii 120, Semen Litchi 90, Semen Astragali Complanati 120, Flos Caryophylli 120, Lignum Aquilariae Resinatum 10, Radix Polygalae 50.
Preparation method:
1., after Radix Ginseng decocts with water, filter and obtain filtrate, again filtrate is condensed into thick paste;
2., Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae seven flavors add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain thick paste;
3., with above-mentioned 1., 2. two kinds of thick pastes obtaining of step mix, dry, pulverize, make powder;
4., Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately are made powder.
5., will be 3., 4. two kinds of powder mixes in the step are even, cross the 80-120 mesh sieve, as capsule heartwood material mixed powder, the sterilization back adds glycerol, press mixed powder: the weight ratio of glycerol=1: 2 is mixed mixing, encapsulates, and is pressed into soft capsule;
6., after drying, packing is made patent medicine.
Claims (6)
1, a kind of treatment traditional tonic medicine of suffering from a deficiency of the kidney is characterized in that the percentage by weight raw material of Chinese medicine preparation is: Radix Ginseng 12～18, Herba Cistanches 12～18, Radix Rehmanniae Preparata 12～18, Herba Epimedii 6～12, Fructus Lycii 12～18, Semen Litchi 4～9, Semen Astragali Complanati 6～12, Flos Caryophylli 6～12, Lignum Aquilariae Resinatum 1～5, Radix Polygalae 1～5.
2, the treatment according to claim 1 traditional tonic medicine of suffering from a deficiency of the kidney is characterized in that the percentage by weight raw material of Chinese medicine preparation is: Radix Ginseng 14～16, Herba Cistanches 14～16, Radix Rehmanniae Preparata 14～16, Herba Epimedii 8～10, Fructus Lycii 14～16, Semen Litchi 6～8, Semen Astragali Complanati 8～10, Flos Caryophylli 8～10, Lignum Aquilariae Resinatum 1～3, Radix Polygalae 1～3.
3, the preparation method of the treatment as claimed in claim 1 traditional tonic medicine of suffering from a deficiency of the kidney is characterized in that carrying out according to the following steps:
1., seven flavor Chinese medicines such as Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain the medicinal liquid thick paste;
2., Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately obtain 200～300 purpose fine powders, mixing obtains mixed powder;
3., with the thick paste that makes and Radix Ginseng, Flos Caryophylli, Lignum Aquilariae Resinatum mixed powder, join in proportion in the oil-based solvent, behind the mixing, make its evenly be suspended in the solvent capsule psychological treatment liquid, again capsule psychological treatment liquid and softgel shell are pressed into soft capsule at 25～28 ℃ of enclose.
4., after drying, packing is made patent medicine.
4, the preparation method of the treatment as claimed in claim 1 traditional tonic medicine of suffering from a deficiency of the kidney is characterized in that carrying out according to the following steps:
1., after Radix Ginseng decocts with water, filter and obtain filtrate, again filtrate is condensed into thick paste;
2., Herba Cistanches, Radix Rehmanniae Preparata, Herba Epimedii, Fructus Lycii, Semen Litchi, Semen Astragali Complanati, Radix Polygalae seven flavors add hydration and decoct after-filtration and obtain filtrate, with concentrating filter liquor, precipitate with ethanol, leave standstill, filter, reclaim ethanol again, concentrate and obtain thick paste;
3., with step 1., two kinds of thick pastes 2. obtaining mix, dry, pulverize, make powder;
4., Flos Caryophylli, Lignum Aquilariae Resinatum pulverize separately are made powder;
5., 3., 4. two kinds of powder mixes are even, cross the 80-120 mesh sieve, as capsule heartwood material, the sterilization back adds solvent, mixing, fill, makes soft capsule with step;
6., after drying, packing is made patent medicine.
5, the preparation method of the traditional tonic medicine of suffering from a deficiency of the kidney according to claim 3 or 4 described treatments is characterized in that oil-based solvent is one or more in liquid polyethylene glycol, isopropyl alcohol, tween 80, glycerol, propylene glycol, the vegetable oil.
6, the preparation method of the traditional tonic medicine of suffering from a deficiency of the kidney according to claim 3 or 4 described treatments is characterized in that softgel shell is made up of gelatin and glycerol, and the weight proportion of gelatin and glycerol is 10: 3.15～10: 3.35.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006101638034A CN1973876A (en) | 2006-12-12 | 2006-12-12 | Chinese medicine for treating kidney deficiency and its prpen |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006101638034A CN1973876A (en) | 2006-12-12 | 2006-12-12 | Chinese medicine for treating kidney deficiency and its prpen |
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| CN1973876A true CN1973876A (en) | 2007-06-06 |
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| CNA2006101638034A Pending CN1973876A (en) | 2006-12-12 | 2006-12-12 | Chinese medicine for treating kidney deficiency and its prpen |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324203A (en) * | 2014-07-17 | 2015-02-04 | 郑攀 | Traditional Chinese medicine composition for treating narcolepsy in spleen-kidney yang deficiency and preparation method thereof |
| CN105754815A (en) * | 2016-05-12 | 2016-07-13 | 黄裕兵 | Liver and kidney nourishing medicinal wine |
| CN106138713A (en) * | 2016-08-18 | 2016-11-23 | 黄裕兵 | One seed ginseng Qi kidney-tonifying wine and preparation method thereof |
-
2006
- 2006-12-12 CN CNA2006101638034A patent/CN1973876A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324203A (en) * | 2014-07-17 | 2015-02-04 | 郑攀 | Traditional Chinese medicine composition for treating narcolepsy in spleen-kidney yang deficiency and preparation method thereof |
| CN104324203B (en) * | 2014-07-17 | 2017-04-19 | 郑攀 | Traditional Chinese medicine composition for treating narcolepsy in spleen-kidney yang deficiency and preparation method thereof |
| CN105754815A (en) * | 2016-05-12 | 2016-07-13 | 黄裕兵 | Liver and kidney nourishing medicinal wine |
| CN106138713A (en) * | 2016-08-18 | 2016-11-23 | 黄裕兵 | One seed ginseng Qi kidney-tonifying wine and preparation method thereof |
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