CN1939410A - Musk medicinal preparation - Google Patents
Musk medicinal preparation Download PDFInfo
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- CN1939410A CN1939410A CNA200510076813XA CN200510076813A CN1939410A CN 1939410 A CN1939410 A CN 1939410A CN A200510076813X A CNA200510076813X A CN A200510076813XA CN 200510076813 A CN200510076813 A CN 200510076813A CN 1939410 A CN1939410 A CN 1939410A
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- moschus
- pharmaceutical preparation
- heart
- ginseng
- calculus bovis
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Abstract
A Chinese medicine 'Musk Xinbao' in the form of tablet, capsule, particle, pill, powder, mixture, softgel, etc for treating palpitation, coronary heart disease, angina pectoris, myocardial infarction, apoplexy coma, cerebral haemarrhage, etc is prepared from 7 Chinese-medicinal materials including toad venom, ginseng, musk, borneol, etc through pulverizing, sieving, mixing, adding auxiliaries, shaping and packing.
Description
The present invention relates to a kind ofly have aromatic herbs activating YANG, invigorate vital energy and reinforce the heart, heat-clearing and toxic substances removing, relieving convulsion effect of having one's ideas straightened out, be used for the pharmaceutical preparation of obstruction of qi in the chest and cardialgia, uncomfortable in chest, chest pain, shortness of breath and palpitation, coronary heart disease, angina pectoris, myocardial infarction, apoplectic coma, cerebral hemorrhage, encephalitis, toxic encephalopthy, wherein the prescription of each raw material is:
Venenum Bufonis 2-10 part Radix Ginseng extract 30-80 part Moschus 2-10 part
Styrax 2-10 part Calculus Bovis 2-10 part Cortex Cinnamomi 30-80 part
Borneolum Syntheticum 20-60 part
Moschus in the prescription comprises natural Moschus and artificial Moschus; Calculus Bovis comprises natural Calculus Bovis and artificial Calculus Bovis and Calculus Bovis cultivating; Radix Ginseng comprises Radix Ginseng, wild ginseng, Park Ginseng, Korean Ginseng, Radix Panacis Quinquefolii.
Radix Ginseng extract:
Method for making: with Radix Ginseng or wild ginseng or Park Ginseng or Korean Ginseng or Radix Panacis Quinquefolii section, with 75% alcohol reflux 3 times, merge backflow, filter, the recovery solvent is condensed into the thick paste shape, at drying under reduced pressure below 80 ℃, promptly.
This product is the dry extract that Radix Ginseng or wild ginseng or Park Ginseng or Korean Ginseng or Radix Panacis Quinquefolii are made through extraction, contains Radix Ginseng total saponins and should be not less than 7%.
Musk medicinal preparation of the present invention, wherein the prescription of each raw material is:
Venenum Bufonis 4-6 part Radix Ginseng extract 50-80 part Moschus 4-8 part
Styrax 8-10 part Calculus Bovis 8-10 part Cortex Cinnamomi 30-50 part
Borneolum Syntheticum 20-40 part.
The present invention also provides the preparation method of musk medicinal preparation pill, powder, tablet, lozenge, granule, capsule, drop pill, aerosol, injection, unguentum, aerosol or spray, oral solution.
For achieving the above object, the present invention also provides the preparation method of the precious pharmaceutical preparation of the Moschus heart:
Embodiment 1: the method for preparing the precious pharmaceutical preparation pill of the Moschus heart:
The first step: according to above-mentioned prescription, the powder of getting it filled respectively.
Second step: above seven flavor medicine material, all be ground into impalpable powder, cross 100 orders with top sieve, standby.
The 3rd step: add appropriate amount of starch, mixing, with the general ball of Chinese liquor, the Pulvis Fumi Carbonisatus coating, polishing, the desiccant drying, promptly.
Embodiment 2: the method for preparing the precious pharmaceutical preparation capsule of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: add an amount of adjuvant as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, ethanol, mixing, encapsulated, promptly.
Embodiment 3: the method for preparing the precious pharmaceutical preparation tablet of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: add an amount of adjuvant as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, ethanol, mixing is granulated, tabletting, and coating, promptly.
Embodiment 4: the method for preparing the precious pharmaceutical preparation lozenge of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: add an amount of adjuvant as Mel, glutinous rice flour and stick together,, rebuild, dry in the shade with touching tool compression moulding or pinching the type of being twisted into, packing, promptly.
Embodiment 5: the method for preparing the precious pharmaceutical preparation granule of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: add an amount of material as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, ethanol, mixing makes granule, packing, promptly.
Embodiment 6: the method for preparing the precious pharmaceutical preparation powder of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: direct packaging or add an amount of adjuvant as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, ethanol, mixing, packing, promptly.
Embodiment 6: the method for preparing the precious pharmaceutical preparation mixture of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: add an amount of adjuvant as sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, water, ethanol, antiseptic, mixing, packing, promptly.
Embodiment 7: the method for preparing the agent of the precious pharmaceutical preparation soft capsule of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
Second step: adds an amount of adjuvant as: vegetable oil, glycerol compacting or droplet make soft capsule, packing, promptly.
Embodiment 8: the method for preparing the precious pharmaceutical preparation drop pill of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: mix homogeneously fine powder, add an amount of adjuvant as Polyethylene Glycol, gelatin, stearic acid, glyceryl monostearate, hydrogenated vegetable oil, ethanol, stir, 85 ℃ of insulations are condensed fluid (condensation temperature is 12-14 ℃) with the liquid paraffin, drip to make ball (dripping speed is 60 droplets/minute), absorb condensed fluid, use the Pulvis Fumi Carbonisatus coating, the desiccant drying, promptly.
Embodiment 9: the method for preparing the precious pharmaceutical preparation unguentum of the Moschus heart:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: add an amount of adjuvant as starch, dextrin, sucrose, cellulose, antiseptic, ethanol, mixing, packing, promptly.
Embodiment 10: the method for preparing precious pharmaceutical preparation aerosol of the Moschus heart or spray:
The first step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: the first step)
Second step: the embodiment 1 (method for preparing the precious pharmaceutical preparation pill of the Moschus heart: second step)
The 3rd step: direct packaging or an amount of tetrafluoride gas ethane, heptafluoro-propane, dichlorodifluoromethane, isceon, dichlorotetra-fluoroethane, nitrogen, carbon dioxide, the nitrous oxide of adding in high-pressure closed vessel, reinstall in the container of suitable withstand voltage band valve, packing, promptly.
Another characteristics of the present invention are that taking dose is little, need only take 50 milligrams at every turn, and maximum dose once is no more than 200 milligrams.
The precious pharmaceutical preparation of the Moschus heart is on the basis of Traditional Chinese medical theory, study in conjunction with modern Chinese medicine, the having aromatic herbs activating YANG, invigorate vital energy and reinforce the heart of invention, heat-clearing and toxic substances removing, relieving convulsion effect of having one's ideas straightened out, be used for the pharmaceutical preparation of obstruction of qi in the chest and cardialgia, uncomfortable in chest, chest pain, shortness of breath and palpitation, coronary heart disease, angina pectoris, myocardial infarction, apoplectic coma, cerebral hemorrhage, encephalitis, toxic encephalopthy, wherein Venenum Bufonis heart tonifying, pain relieving, Moschus are had one's ideas straightened out refreshment, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain altogether for monarch drug; Ginseng qi-tonifying, clear away heart-fire detoxify, eliminate phlegm for resuscitation, cool liver endogenous wind stopping is a ministerial drug; The refreshment pain relieving of having one's ideas straightened out of Styrax, Borneolum Syntheticum is an adjuvant drug; Cortex Cinnamomi promoting blood circulation to restore menstrual flow, dispersing cold for relieving pain are messenger drug, to help the strong and promoting blood circulation to restore menstrual flow of Moschus of Venenum Bufonis, the function of reducing swelling and alleviating pain.The inventor is from May, 2002---passes through in February, 2005 obstruction of qi in the chest and cardialgia patient 165 people, patient uncomfortable in chest 145 people, chest pain patient 253 people, shortness of breath and palpitation patient 202 people; Patients with coronary heart disease 280 people, patient with angina pectoris 146 people, myocardial infarction patient's 120 people's clinical observation on the therapeutic effect, patients with coronary heart disease 280 people, patient with angina pectoris 146 people, myocardial infarction patient 120 people, apoplectic coma patient 165 people, patients with cerebral hemorrhage 145 people, encephalitis patient 253 people, toxic encephalopthy patient's 82 people's clinical observation on the therapeutic effect the results are shown in Table 1.
Table 1: the precious pharmaceutical preparation observation of curative effect of Moschus heart catalog
By Clinical analysis, prove that the precious pharmaceutical preparation of the Moschus heart is at treatment obstruction of qi in the chest and cardialgia, uncomfortable in chest, chest pain, shortness of breath and palpitation, coronary heart disease, angina pectoris, myocardial infarction, apoplectic coma, cerebral hemorrhage, encephalitis, toxic encephalopthy determined curative effect.
Claims (4)
1, a kind ofly have aromatic herbs activating YANG, invigorate vital energy and reinforce the heart, heat-clearing and toxic substances removing, relieving convulsion effect of having one's ideas straightened out, be used for the pharmaceutical preparation of obstruction of qi in the chest and cardialgia, uncomfortable in chest, chest pain, shortness of breath and palpitation, coronary heart disease, angina pectoris, myocardial infarction, apoplectic coma, cerebral hemorrhage, encephalitis, toxic encephalopthy, wherein the prescription of each raw material is:
Venenum Bufonis 2-10 part Radix Ginseng extract 30-80 part Moschus 2-10 part
Styrax 2-10 part Calculus Bovis 2-10 part Cortex Cinnamomi 30-80 part
Borneolum Syntheticum 20-60 part
Moschus in the prescription comprises natural Moschus and artificial Moschus; Calculus Bovis comprises natural Calculus Bovis and artificial cattle
Huang and Calculus Bovis cultivating; Radix Ginseng comprises Radix Ginseng, wild ginseng, Park Ginseng, Korean Ginseng, Radix Panacis Quinquefolii.
2, pharmaceutical preparation according to claim 1, wherein the prescription of raw material is:
Venenum Bufonis 4-6 part Radix Ginseng extract 50-80 part Moschus 4-8 part
Styrax 8-10 part Calculus Bovis 8-10 part Cortex Cinnamomi 30-50 part
Borneolum Syntheticum 20-40 part.
3, pharmaceutical preparation according to claim 1 and 2 is characterized in that the preparation method of said pharmaceutical preparation is:
Above seven flavor medicine material all is ground into impalpable powder, crosses 100 orders with top sieve, and mix homogeneously is added in the polyethylene glycol 6000 that has melted, stir, 85 ℃ of insulations are condensed fluid with the liquid paraffin, drip to make ball, absorb condensed fluid, use the Pulvis Fumi Carbonisatus coating, the desiccant drying, promptly.
4,, it is characterized in that said pharmaceutical preparation is pill, powder, tablet, lozenge, granule, capsule, pellet, drop pill, aerosol, injection, unguentum, syrup, oral solution according to claim 1 or 2 or 3 described musk medicine for protecting heart.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200510076813XA CN1939410A (en) | 2005-06-17 | 2005-06-17 | Musk medicinal preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200510076813XA CN1939410A (en) | 2005-06-17 | 2005-06-17 | Musk medicinal preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1939410A true CN1939410A (en) | 2007-04-04 |
Family
ID=37958112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA200510076813XA Pending CN1939410A (en) | 2005-06-17 | 2005-06-17 | Musk medicinal preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1939410A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102920923A (en) * | 2012-11-18 | 2013-02-13 | 李承平 | Compound styrax tablets for resuscitation |
| CN104435114A (en) * | 2014-03-28 | 2015-03-25 | 上海和黄药业有限公司 | Method for preparing cardiovascular disease drug micropills |
| CN105055771A (en) * | 2015-07-30 | 2015-11-18 | 吴斌 | Chinese herbal medicament for treating coronary heart disease |
| CN109125390A (en) * | 2018-09-29 | 2019-01-04 | 内蒙古康恩贝药业有限公司圣龙分公司 | A kind of Moschus leads to heart dripping pill and preparation method thereof |
-
2005
- 2005-06-17 CN CNA200510076813XA patent/CN1939410A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102920923A (en) * | 2012-11-18 | 2013-02-13 | 李承平 | Compound styrax tablets for resuscitation |
| CN104435114A (en) * | 2014-03-28 | 2015-03-25 | 上海和黄药业有限公司 | Method for preparing cardiovascular disease drug micropills |
| CN104435114B (en) * | 2014-03-28 | 2018-04-13 | 上海和黄药业有限公司 | A kind of preparation method of cardiovascular disease medicine particulate ball |
| CN105055771A (en) * | 2015-07-30 | 2015-11-18 | 吴斌 | Chinese herbal medicament for treating coronary heart disease |
| CN109125390A (en) * | 2018-09-29 | 2019-01-04 | 内蒙古康恩贝药业有限公司圣龙分公司 | A kind of Moschus leads to heart dripping pill and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20070404 |