CN1933825A - N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途 - Google Patents

N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途 Download PDF

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Publication number
CN1933825A
CN1933825A CNA2005800095602A CN200580009560A CN1933825A CN 1933825 A CN1933825 A CN 1933825A CN A2005800095602 A CNA2005800095602 A CN A2005800095602A CN 200580009560 A CN200580009560 A CN 200580009560A CN 1933825 A CN1933825 A CN 1933825A
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CN
China
Prior art keywords
sci
general formula
compound
alkyl
phenyl
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CNA2005800095602A
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English (en)
Chinese (zh)
Inventor
R·贝尔蒂尼
F·科洛塔
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Dompe SpA
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Dompe PhaRMa SpA
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Application filed by Dompe PhaRMa SpA filed Critical Dompe PhaRMa SpA
Publication of CN1933825A publication Critical patent/CN1933825A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA2005800095602A 2004-03-25 2005-03-17 N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途 Pending CN1933825A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04007177.1 2004-03-25
EP04007177A EP1579859B1 (en) 2004-03-25 2004-03-25 Use of N-(2-aryl-propionyl)-sulfonamides for the treatment of spinal cord injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2012104176511A Division CN103054842A (zh) 2004-03-25 2005-03-17 N-(2-芳基-丙酰基)-磺酰胺在制备治疗脊髓损伤用的药物中的用途

Publications (1)

Publication Number Publication Date
CN1933825A true CN1933825A (zh) 2007-03-21

Family

ID=34854609

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2005800095602A Pending CN1933825A (zh) 2004-03-25 2005-03-17 N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途
CN2012104176511A Pending CN103054842A (zh) 2004-03-25 2005-03-17 N-(2-芳基-丙酰基)-磺酰胺在制备治疗脊髓损伤用的药物中的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2012104176511A Pending CN103054842A (zh) 2004-03-25 2005-03-17 N-(2-芳基-丙酰基)-磺酰胺在制备治疗脊髓损伤用的药物中的用途

Country Status (23)

Country Link
US (1) US20090030083A1 (https=)
EP (1) EP1579859B1 (https=)
JP (1) JP4988550B2 (https=)
KR (2) KR101312235B1 (https=)
CN (2) CN1933825A (https=)
AT (1) ATE347883T1 (https=)
AU (1) AU2005226901B2 (https=)
BR (1) BRPI0509167A (https=)
CA (1) CA2555162C (https=)
CY (1) CY1107562T1 (https=)
DE (1) DE602004003673T2 (https=)
DK (1) DK1579859T3 (https=)
ES (1) ES2279248T3 (https=)
IL (1) IL177169A (https=)
MX (1) MXPA06009085A (https=)
NO (1) NO20064793L (https=)
NZ (1) NZ548917A (https=)
PL (1) PL1579859T3 (https=)
PT (1) PT1579859E (https=)
RU (1) RU2396075C2 (https=)
SI (1) SI1579859T1 (https=)
WO (1) WO2005092315A1 (https=)
ZA (1) ZA200608517B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159674A (zh) * 2013-04-03 2013-06-19 苏州安诺生物医药技术有限公司 2-苯烷酰胺类化合物及其制备方法、药物组合物和用途
CN103172547A (zh) * 2011-12-20 2013-06-26 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2066335A4 (en) * 2006-09-26 2010-01-20 Univ Case Western Reserve ZYTOKINSIGNALISIERUNG
EP2308484A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
KR20220064039A (ko) 2020-11-11 2022-05-18 정성삼 척수 손상 예방 또는 치료용 조성물
KR102320780B1 (ko) 2021-01-29 2021-11-02 정성삼 척추 통증 완화 및 척추 유연성 개선을 위한 조성물 및 이의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303249B1 (it) * 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
US6419944B2 (en) * 1999-02-24 2002-07-16 Edward L. Tobinick Cytokine antagonists for the treatment of localized disorders
IT1318466B1 (it) * 2000-04-14 2003-08-25 Dompe Spa Ammidi di acidi r-2-(amminoaril)-propionici, utili nella prevenzionedell'attivazione leucocitaria.
ITMI20010206A1 (it) * 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103172547A (zh) * 2011-12-20 2013-06-26 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用
CN103172547B (zh) * 2011-12-20 2016-10-12 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用
CN103159674A (zh) * 2013-04-03 2013-06-19 苏州安诺生物医药技术有限公司 2-苯烷酰胺类化合物及其制备方法、药物组合物和用途

Also Published As

Publication number Publication date
MXPA06009085A (es) 2007-04-02
AU2005226901A1 (en) 2005-10-06
EP1579859A1 (en) 2005-09-28
KR101312235B1 (ko) 2013-09-26
CA2555162C (en) 2012-11-27
IL177169A0 (en) 2006-12-10
DK1579859T3 (da) 2007-04-10
DE602004003673T2 (de) 2007-10-04
PT1579859E (pt) 2007-03-30
CY1107562T1 (el) 2013-03-13
BRPI0509167A (pt) 2007-09-11
NZ548917A (en) 2010-06-25
PL1579859T3 (pl) 2007-06-29
CA2555162A1 (en) 2005-10-06
DE602004003673D1 (de) 2007-01-25
SI1579859T1 (sl) 2007-04-30
AU2005226901B2 (en) 2011-06-02
KR101327150B1 (ko) 2013-11-06
CN103054842A (zh) 2013-04-24
KR20070018015A (ko) 2007-02-13
JP4988550B2 (ja) 2012-08-01
WO2005092315A1 (en) 2005-10-06
KR20120104445A (ko) 2012-09-20
ES2279248T3 (es) 2007-08-16
IL177169A (en) 2010-12-30
ZA200608517B (en) 2008-04-30
RU2396075C2 (ru) 2010-08-10
NO20064793L (no) 2006-10-23
EP1579859B1 (en) 2006-12-13
US20090030083A1 (en) 2009-01-29
RU2006137575A (ru) 2008-04-27
ATE347883T1 (de) 2007-01-15
JP2007530478A (ja) 2007-11-01

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