CN1931198A - Wound protecting and treating smearing prepn - Google Patents
Wound protecting and treating smearing prepn Download PDFInfo
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- CN1931198A CN1931198A CNA2006100486941A CN200610048694A CN1931198A CN 1931198 A CN1931198 A CN 1931198A CN A2006100486941 A CNA2006100486941 A CN A2006100486941A CN 200610048694 A CN200610048694 A CN 200610048694A CN 1931198 A CN1931198 A CN 1931198A
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- wound
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- healing
- protecting
- smearing
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Abstract
Of the wound protecting and treating smearing preparation, each 100 ml contains rosin in 0.01-30 g, beeswax in 0.01-30 g, ethanol in 5-75 ml, turpentine in 0.01-9 ml, PVA in 1-30 g, except pure water. The wound protecting and treating smearing preparation can form one permeable transparent protecting film on skin to isolate bacteria and dirt, reduce pain and itching, speed the healing of wound, avoid scabbing and reduce scar. The wound protecting and treating smearing preparation is suitable for not only small wound caused by burns, scalds, abrasion, etc but also superficial wound after treatment, skin ulceration, etc. It has application convenience and safety, and excellent patient's compliance.
Description
Technical field
The present invention relates to a kind of wound surface smearing agent, the liniment of especially a kind of protection and treatment wound surface belongs to medical product.
Background technology
In daily life, work, be comparatively common because of a variety of causes causes the little wound surface of body surface, as burn, scald, scratch, scuffing etc.Traditional processing method is: for burn, scald wound, generally all use the ointments preparation, and the wound surface that abrades, scratches then uses adhesive bandage mostly.The easy pollution clothes of ointments preparation also forms the secondary pollution of wound surface easily; Pain when adhesive bandage is changed dressings especially very easily causes wound infection, inflammation under the regimen condition, moreover the specification of adhesive bandage and size are fixed, and the wound surface size is then irregular to differ, and will be subjected to significant limitation so use.Therefore, be necessary prior art is improved.
Summary of the invention
For overcoming the prior art above shortcomings, the invention provides and a kind ofly be common to the little wound surface of body surface such as burn, scald, scratch, scuffing, and the protection of the shallow table wound that causes after department of dermatologry and the laser therapy of face-lifting section and prevent the liniment of bacterial infection.
The present invention realizes by following technical proposal: a kind of Wound protecting and treating smearing preparation is characterized in that containing in every 100ml product following raw materials according:
Colophonium 0.01-30g Cera Flava 0.01-30g
Ethanol 5-75ml Oleum Terebinthinae 0.01-9ml
Polyvinyl alcohol 1-30g surplus is a purified water.
Described Wound protecting and treating smearing preparation is to contain following raw materials according in every 100ml product:
Colophonium 0.1-20g Cera Flava 0.1-20g
Ethanol 5-75ml Oleum Terebinthinae 0.1-9ml
Polyvinyl alcohol 1-30g surplus is a purified water.
Wherein, Oleum Terebinthinae has volatilization, and ethanol has sterilization, bactericidal action; after polyvinyl alcohol, Cera Flava, Oleum Terebinthinae attach to wound surface, can form the Wound protection film of layer of transparent, infect again to prevent wound; the while accelerating wound healing, and the effect that significantly alleviates wound pain is arranged.
The present invention is raw materials used to be commercial commodity, and wherein concentration of alcohol is 95%, and rank is medicinal rank.
Described Wound protecting and treating smearing preparation is liquid preparation or is unguentum.
The present invention has following advantage and effect: adopt such scheme; make product can on wound surface, form the skin care film of layer of transparent; effective isolate bacteria and dirt; alleviate pain and prodding and itching feeling in the agglutination; accelerating wound healing; do not form a scab, can effectively alleviate cicatrix, and wound healing is good.The protecting film that uses the back to form has air permeability and good, the property covered, and can stop extraneous foreign body and the microorganism intrusion to wound, has the effect of protecting wound surface, promotion wound healing, removing the rotten and letting fresh grow.This product is not only applicable to the little wound surface of body surface such as burn, scald, scratch, scuffing, cold injury, mosquito bite, can be used for the shallow table wound that causes after department of dermatologry and the laser therapy of face-lifting section, the skin ulceration that the diabetes patient causes because of wound etc. yet.Only this product evenly need be spread upon in right amount wound surface during use through cleaning; promptly form ventilative, soft resilient protecting film after the drying; the wound healing caudacoria can come off voluntarily; compare with adhesive bandage with traditional ointment; safe in utilization, convenient; can smear arbitrarily according to the wound surface size, the patient has good compliance.
For showing the present invention's effect, now will use clinical effectiveness of the present invention to be reported as follows:
1, clinical data:
1.1 physical data: 50 routine patients are the department of dermatologry outpatient, male 24 examples, women 26 examples, age 13-86 year, average 57 ± 1 years old.CO
2Laser operation back 47 examples, 1 example of chapping, skin is dampened 2 examples.
1.2 wound surface clinical manifestation: adopt CO
2The skin lesion of laser operation treatment is vegetation, and wherein condyloma acuminatum 10 routine areas do not wait from bunch collection single pimple to a 2 * 3cm speckle; Verruca vulgaris 23 examples are about 0.5 * 1cm to 1 * 1cm; Plantar wart 4 examples are about 1 * 1cm; Inflammatory granuloma 4 examples are about 0.5 * 0.5cm; Seborrheic keratosis 4 examples are about 0.5 * 1cm; Nevus cell nevus 2 examples are about 0.1 * 0.2cm; More than 47 examples be CO
2There is not the wound surface of infection behind the laser operation; 1 example of chapping reaches skin corium deeply; Skin is dampened 2 examples, and shallow table is hemorrhage on a small quantity, does not have and infects.
1.3 test method: the test with Wound protecting and treating smearing preparation by the applicant---Kunming Chuangbang Medical Equipment Co., Ltd. provides.Lot number: (20060501).Packing: bottled.Specification: 5ml/ props up.By the doctor in charge to the wound surface scrutiny after, with normal saline cleaning, sterilized cotton ball is dried, and Wound protecting and treating smearing preparation is evenly spread upon wound surface, treats bone dry, can repeat coating as required.Advise patient's further consultation after 3 days, smear once more, a week is observed healing state.
2. appraisal procedure and evaluation criterion:
2.1 appraisal procedure: after smearing 3-7 days with Wound protecting and treating smearing preparation, observe the wound healing situation, wound is divided into I class, II class wound.Healing is divided into Class A, Class B, Class C.
2.2 evaluation criterion: I class wound: refer to aseptic wound.II class wound: the wound that has pollution when referring to wound.First class healing: refer to that wound healing is good, do not have untoward reaction.Second class healing: refer to healing and inflammatory reaction is arranged, as redness, scleroma, hematoma, hydrops etc. but suppuration.Third class healing: refer to that otch suppurates, and need do processing such as incision and drainage.
3. untoward reaction: in experimentation, do not find untoward reaction and side effect.
4. result: totally 50 examples 75 place's wounds, be II class wound, the first class healing, healing rate is 100%.
| The sick kind | The example number | 3 days further consultation situations | One all further consultation situations | Healing rate xml:namespace prefix=0/＞xml:namespace prefix=0/＞xml:namespace |
| Condyloma acuminatum | 10 | Wound surface drying, nothing redness | Healing | 100％ |
| Verruca vulgaris | 23 | Wound surface drying, nothing redness | Healing | 100％ |
| Plantar wart | 4 | The wound surface drying | Healing | 100％ |
| The inflammatory granuloma | 4 | Do not have red and swollen | Healing | 100％ |
| Seborrheic keratosis | 4 | Wound surface drying, nothing redness | Healing | 100％ |
| Nevus cell nevus | 2 | Do not have red and swollen | Healing | 100％ |
| Chap | 1 | The wound surface drying | Healing | 100％ |
| Skin is dampened | 2 | The wound surface drying | Healing | 100％ |
5. discuss: Wound protecting and treating smearing preparation is made up of polyvinyl alcohol, Cera Flava, Colophonium, Oleum Terebinthinae, ethanol, purified water.Oleum Terebinthinae has volatilization, and ethanol has disinfective action, and polyvinyl alcohol, Cera Flava, Colophonium thin film attach to wound surface, and the protecting film of layer of transparent can be provided for wound, prevents that wound from infecting once again, accelerating wound healing.And have and significantly alleviate the wound pain effect.This product is easy to use, and patient can smear voluntarily, needn't tear the reason thin film in repeated use, treats that the wound healing thin film can come off voluntarily.Compliance is preferably arranged.
6. clinical trial conclusion: this clinical test results shows that this product has ventilative, waterproof, sterilization, the creation of protecting antifouling, that isolate bacteria infects and uses.Be applicable to the shallow table wound of skin minor operation, scratch, the simple and easy wound of protecting of shallow table such as scratch, little boiling hot work, fingernail clavus.
7. points for attention:
7.1 can only external.
7.2 the careful usefulness of ethanol allergy sufferers.
7.3 following situation can not be used this product
1) animal bite;
2) health extensive wound;
3) wound the infected.
7.4 not being used for ophthalmic reaches near the eyes.
7.5 avoid high temperature, away from Mars, naked light.
Clinical trial situation about Wound protecting and treating smearing preparation
Patient age: 35 ± 2.2 years old, women's 9 examples, male's 31 examples.
One, all patients are all in daily routines, as play ball, traumatic injury when removing object, scratch or scratched by sharp-pointed article.Wound more shallow (being limited to epidermis, skin corium).The wound scope is less, and general length is no more than 5CM.Trial product adopts the Wound protecting and treating smearing preparation of being produced by Kunming Chuangbang Medical Equipment Co., Ltd., and every 5ml/ props up, standard Q/KCB 01-2006.
Two, test method: after all wounds are done detailed inspection by surgeon, do thorough disinfection (three scourings), dry with sterilized cotton ball then with painless iodine cotton balls; Wound protecting and treating smearing preparation is evenly spread upon wound surface in right amount; wait its bone dry,, can repeat coating as needs.After the patient takes Wound protecting and treating smearing preparation home, advise be coated with once its every day, the wound healing situation is observed in week back return visit.All 40 routine patients all do not have iodine or ethanol allergies.
Three, evaluation methodology: after smearing a week with Wound protecting and treating smearing preparation, observe the wound healing situation, wound is divided into I class, II class wound.Healing is divided into Class A, Class B, Class C healing, statistics healing state rate.
Four, evaluation criterion: I class wound: refer to aseptic wound.II class wound: the wound that has pollution when referring to wound.First class healing: refer to that wound healing is good, do not have the initial stage healing of untoward reaction.The second class healing: refer to that wound healing is not good enough, healing place has inflammatory reactions such as red and swollen scleroma.Third class healing: refer to that wound criticizes pus, need from newly doing Surgery Treatment.
Five, result of the test: all wounds (totally 40 examples 62 place's wounds), be II class wound, the first class healing, healing rate is 100%.
Six, untoward reaction: 11 routine patients (accounting for sum 30%) are arranged, and wound has stronger sensation of pricking when smearing for initial 1 to 2 time, disappears later on.
Seven, effect analysis: Wound protecting and treating smearing preparation is made up of polyvinyl alcohol, Cera Flava, Colophonium, Oleum Terebinthinae, ethanol, purified water.Oleum Terebinthinae has volatilization, and ethanol has disinfective action, and polyvinyl alcohol, Cera Flava, Colophonium thin film attach to wound surface, gives the protecting film that layer of transparent is provided for wound, prevents that wound from infecting again, accelerating wound healing.Because wound is done wet suitable, is difficult for incrustation, can effectively alleviate the painful gargalesthesia of healing stage, prevent that wound is by bacterial infection; The protection wound is ventilative, waterproof, antifouling, isolate bacteria infect.Provide layer of transparent softish protecting film to wound, accelerating wound.40 examples, 62 place's wounds are II class wound, the healing of first group, and healing rate is 100%.According to another 5 female patient reactions, behind the use Wound protecting and treating smearing preparation, expose wound and be difficult for being discovered by other people, be easy to the secret protection of living.
Eight, conclusion (of pressure testing): this clinical test results shows that the Wound protecting and treating smearing preparation external has sterilization, ventilative, waterproof, the creation of protecting antifouling, that isolate bacteria infects and uses.Can relax painful gargalesthesia of healing stage and accelerating wound.
Nine, indication, contraindication, points for attention:
Be applicable to the little wound of skin.As incised wound, scratch, the simple disinfection of shallow table such as scratch, little scald, fingernail clavus protects wound.
Taboo item: the careful usefulness of ethanol allergy sufferers.
Points for attention:
1. can only be used for wound.
2. following situation can not be used this product: 1). animal bite.2). the health extensive wound.3). wound the infected must not use this product.
3. must not run into eyes when using this product.
4. please this product is placed on place away from child, at once if hospital admission is please removed in misuse.
5. this product should be avoided high temperature, away from Mars, naked light.
The specific embodiment
Below in conjunction with embodiment the present invention is described further.
Embodiment 1
Take off the row raw material: Colophonium 0.1g, Cera Flava 0.1g, polyvinyl alcohol 10g, purified water 940ml, ethanol 50ml and Oleum Terebinthinae 0.1ml;
Make the 1000ml product through following method:
A: Colophonium, Cera Flava, Oleum Terebinthinae are dissolved in the ethanol, standby;
B: polyvinyl alcohol is soaked, heats and dissolve with purified water, standby;
C: the reserve liquid with the A step under stirring condition slowly adds in the reserve liquid of B step, and surplus is supplied to be mixed with purified water and got final product.
Embodiment 2
Take off the row raw material, after mixing, get product:
The formulated 1000ml product of Colophonium 20g, Cera Flava 50g, polyvinyl alcohol 100g, purified water 500ml, ethanol 300ml and Oleum Terebinthinae 30ml.
Embodiment 3
Take off the row raw material, after mixing, get product:
The formulated 1000ml product of Colophonium 50g, Cera Flava 30g, polyvinyl alcohol 150g, purified water 600ml, ethanol 150ml and Oleum Terebinthinae 20ml.
Embodiment 4
Take off the row raw material, after mixing, get product:
The formulated 1000ml product of Colophonium 300g, Cera Flava 30g, polyvinyl alcohol 300g, purified water 200ml, ethanol 150ml and Oleum Terebinthinae 20ml.
Embodiment 5
Take off the row raw material, after mixing, get product:
The formulated 1000ml product of Colophonium 200g, Cera Flava 300g, polyvinyl alcohol 100g, purified water 280ml, ethanol 100ml and Oleum Terebinthinae 20ml.
Embodiment 6
Take off the row raw material, after mixing, get product:
The formulated 1000ml product of Colophonium 100g, Cera Flava 100g, polyvinyl alcohol 150g, purified water 280ml, ethanol 390ml and Oleum Terebinthinae 30ml.
Claims (4)
1, a kind of Wound protecting and treating smearing preparation is characterized in that containing in every 100ml product following raw materials according:
Colophonium 0.01-30g Cera Flava 0.01-30g
Ethanol 5-75ml Oleum Terebinthinae 0.01-9ml
Polyvinyl alcohol 1-30g surplus is a purified water.
2, Wound protecting and treating smearing preparation according to claim 1 is characterized in that containing in every 100ml product following raw materials according:
Colophonium 0.1-20g Cera Flava 0.1-20g
Ethanol 5-75ml Oleum Terebinthinae 0.1-9ml
Polyvinyl alcohol 1-30g surplus is a purified water.
3, Wound protecting and treating smearing preparation according to claim 1 is characterized in that described raw material is commercial commodity, and wherein concentration of alcohol is 95%, and rank is medicinal rank.
4, Wound protecting and treating smearing preparation according to claim 1 is characterized in that described Wound protecting and treating smearing preparation is liquid preparation or is unguentum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100486941A CN100391479C (en) | 2006-09-25 | 2006-09-25 | Wound protecting and treating smearing prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100486941A CN100391479C (en) | 2006-09-25 | 2006-09-25 | Wound protecting and treating smearing prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1931198A true CN1931198A (en) | 2007-03-21 |
| CN100391479C CN100391479C (en) | 2008-06-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100486941A Expired - Fee Related CN100391479C (en) | 2006-09-25 | 2006-09-25 | Wound protecting and treating smearing prepn |
Country Status (1)
| Country | Link |
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| CN (1) | CN100391479C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102166369A (en) * | 2010-11-29 | 2011-08-31 | 吴克 | Liquid woundplast and preparation technology thereof |
| CN102579915A (en) * | 2012-03-06 | 2012-07-18 | 杜中勤 | Medicine for treating wound non-healing of diabetics and preparation method thereof |
| CN107519529A (en) * | 2016-06-20 | 2017-12-29 | 重庆灵方三帆生物制药有限公司 | A kind of liquid Wound surface protection film |
| CN107714677A (en) * | 2017-11-10 | 2018-02-23 | 重庆灵方三帆生物制药有限公司 | A kind of liquid Wound surface protection film and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1070051C (en) * | 1997-06-10 | 2001-08-29 | 海内胜 | Substrate for medical paste |
| CN1281259C (en) * | 2004-11-03 | 2006-10-25 | 郎需才 | Leadless plaster medium for Chinese medicine and preparing method |
-
2006
- 2006-09-25 CN CNB2006100486941A patent/CN100391479C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102166369A (en) * | 2010-11-29 | 2011-08-31 | 吴克 | Liquid woundplast and preparation technology thereof |
| CN102579915A (en) * | 2012-03-06 | 2012-07-18 | 杜中勤 | Medicine for treating wound non-healing of diabetics and preparation method thereof |
| CN102579915B (en) * | 2012-03-06 | 2013-07-10 | 杜中勤 | Medicine for treating wound non-healing of diabetics |
| CN107519529A (en) * | 2016-06-20 | 2017-12-29 | 重庆灵方三帆生物制药有限公司 | A kind of liquid Wound surface protection film |
| CN107714677A (en) * | 2017-11-10 | 2018-02-23 | 重庆灵方三帆生物制药有限公司 | A kind of liquid Wound surface protection film and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100391479C (en) | 2008-06-04 |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
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Granted publication date: 20080604 Termination date: 20170925 |