CN1931197A - Health product and medicine containing glossy ganoderma and selenium - Google Patents
Health product and medicine containing glossy ganoderma and selenium Download PDFInfo
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- CN1931197A CN1931197A CN 200610096012 CN200610096012A CN1931197A CN 1931197 A CN1931197 A CN 1931197A CN 200610096012 CN200610096012 CN 200610096012 CN 200610096012 A CN200610096012 A CN 200610096012A CN 1931197 A CN1931197 A CN 1931197A
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- ganoderma
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Abstract
The health product and medicine consists of glossy ganoderma and selenium mainly, and may be used to raise body's immunity and resist various kinds of diseases. Of the product of the present invention, each daily taken unit for adult includes glossy ganoderma in 0.15-15000 mg and selenium in 0.004-400 mcg.
Description
Technical field
The invention belongs to a kind of health product and medicine, specifically a kind of health product and medicine of mainly forming by Ganoderma (including but not limited to the full powder of Ganoderma, Ganoderma spore powder, Ganoderma extract, Ganoderma lucidum by submerged culture liquid and dry powder) and selenium (including but not limited to selenocarrageenan, cereuisiae fermentum rich in selenoaminoacid, selenocysteine, sodium selenite, sodium selenate, selenomethionine).
Background technology
Along with the variation of global climate and environment, the quickening of rhythm of life, the increase of operating pressure, considerable people often is in sub-health state, very easily sick, for effective prophylactic generation, perhaps can obtain the effective treatment and rehabilitation rapidly after sick, people press for a kind of health product and medicine that can improve immunity.
Summary of the invention
The object of the present invention is to provide a kind of Ganoderma and selenic health product and medicine of containing, mainly form, after use, can effectively improve the immunologic function of human body, resist the generation of various diseases by Ganoderma and selenium.
According to technical scheme provided by the invention, this product in each unit mainly by combining the intake that described unit allows for the adult every day in the Ganoderma of ganoderan 0.15mg～15000mg with in the selenium of selenium 0.004 μ g～400 μ g.
Described Ganoderma is one or more in the full powder of Ganoderma, Ganoderma spore powder, Ganoderma extract, Ganoderma lucidum by submerged culture liquid and the Ganoderma lucidum by submerged culture liquid dry powder; Selenium is one or more in selenocarrageenan, cereuisiae fermentum rich in selenoaminoacid, selenocysteine, sodium selenite, sodium selenate, the selenomethionine.
The dosage form of these health product and medicine is: a kind of in oral liquid, tablet, hard capsule, soft capsule, electuary, medicated wine, injection, syrup, the unguentum.
These health product and medicine also contain and manufacture the required adjuvant of various dosage forms, and this adjuvant comprises one or more in microcrystalline Cellulose, maltodextrin, cane sugar powder, mannitol, ethanol, arabic gum, gelatin, Macrogol 4000, sodium carboxymethyl cellulose, polyvinylpyrrolidone, carboxymethylstach sodium, magnesium stearate, starch, xylitol, potassium sorbate, Tween 80, sodium pyrosulfite, the simple syrup.
When the adult used this product, selenic every day, intake the highlyest was no more than 400 μ g/ days, minimum being not less than 0.004 μ g/ days, and intake every day of ganoderan is the highest to be no more than 15000mg/ days, minimum being not less than 0.15mg/ days.
Advantage of the present invention is: Ganoderma and selenium are carried out the health product and the medicine that form after the reasonable combination, can effectively improve the immunologic function of human body, improve body constitution, prevention and the treatment disease of sub-health population.
The specific embodiment
Ganoderma of the present invention includes but not limited to the full powder of Ganoderma, Ganoderma spore powder, Ganoderma extract, Ganoderma lucidum by submerged culture liquid and dry powder, when combination product with the amount of ganoderan weight indicator as proportioning, selenium includes but not limited to selenocarrageenan, cereuisiae fermentum rich in selenoaminoacid, selenocysteine, sodium selenite, sodium selenate, selenomethionine, when combination product with the weight indicator of selenic amount as proportioning.The selenium that took in every day when the adult used this product is the highest to be no more than 400 μ g/ days, minimum being not less than 0.004 μ g/ days, the amount of the ganoderan that take in every day is the highest to be no more than 15000mg/ days, minimum being not less than 0.15mg/ days, ganoderan and selenium can carry out reasonable combination in prescription, the suitable prevent disease of closing of low dose group, middle dosage combination is fit to subhealth state patient, the suitable treatment disease of closing of high dose group.
The dosage form of these health product and medicine is: a kind of in oral liquid, tablet, hard capsule, soft capsule, electuary, medicated wine, injection, syrup, the unguentum.
These health product and medicine also contain and manufacture the required adjuvant of various dosage forms, and this adjuvant comprises one or more in microcrystalline Cellulose, maltodextrin, cane sugar powder, mannitol, ethanol, arabic gum, gelatin, Macrogol 4000, sodium carboxymethyl cellulose, polyvinylpyrrolidone, carboxymethylstach sodium, magnesium stearate, starch, xylitol, potassium sorbate, Tween 80, sodium pyrosulfite, the simple syrup.
Embodiment (following total amount is all in adult's dose of every day)
The full powder of 1 Ganoderma (in ganoderan) 0.15mg; Selenocarrageenan (in selenium) 0.004 μ g; Right amount of auxiliary materials.
2 Ganoderma spore powders (in ganoderan) 1.5mg; Cereuisiae fermentum rich in selenoaminoacid (in selenium) 0.04 μ g; Right amount of auxiliary materials.
3 Ganoderma extracts (in ganoderan) 15mg; Selenocysteine (in selenium) 0.4 μ g; Right amount of auxiliary materials.
4 Ganoderma lucidum by submerged culture liquid (in ganoderan) 150mg; Sodium selenite (in selenium) 4 μ g; Right amount of auxiliary materials.
5 Ganoderma lucidum by submerged culture liquid dry powder (in ganoderan) 1500mg; Sodium selenate (in selenium) 40 μ g; Right amount of auxiliary materials.
The full powder of 6 Ganodermas (in ganoderan) 15000mg; Selenomethionine (in selenium) 400 μ g; Right amount of auxiliary materials.
7 Ganoderma spore powders (in ganoderan) 0.15mg; Selenocarrageenan (in selenium) 400 μ g; Right amount of auxiliary materials.
8 Ganoderma extracts (in ganoderan) 1.5mg; Cereuisiae fermentum rich in selenoaminoacid (in selenium) 40 μ g; Right amount of auxiliary materials.
9 Ganoderma lucidum by submerged culture liquid (in ganoderan) 15mg; Selenocysteine (in selenium) 4 μ g; Right amount of auxiliary materials.
10 Ganoderma lucidum by submerged culture liquid dry powder (in ganoderan) 150mg; Sodium selenite (in selenium) 0.4 μ g; Right amount of auxiliary materials
The full powder of 11 Ganodermas (in ganoderan) 1500mg; Sodium selenate (in selenium) 0.04 μ g; Right amount of auxiliary materials.
12 Ganoderma spore powders (in ganoderan) 15000mg; Selenocysteine (in selenium) 0.004g; Right amount of auxiliary materials.
13 Ganoderma extracts (in ganoderan) 30mg; Selenomethionine (in selenium) 60 μ g; Right amount of auxiliary materials.
14 Ganoderma lucidum by submerged culture liquid (in ganoderan) 120mg; Sodium selenite (in selenium) 240 μ g; Right amount of auxiliary materials.
Full powder+the Ganoderma spore powder of 15 Ganodermas (in ganoderan) 480mg; Selenocarrageenan (in selenium) 60 μ g; Right amount of auxiliary materials.
16 Ganoderma extracts+Ganoderma lucidum by submerged culture liquid (in ganoderan) 80mg; Cereuisiae fermentum rich in selenoaminoacid (in selenium) 400 μ g; Right amount of auxiliary materials.
The full powder of 17 Ganodermas (in ganoderan) 120mg; Selenocysteine+sodium selenite (in selenium) 15 μ g; Right amount of auxiliary materials.
The 18 full powder of Ganoderma lucidum by submerged culture liquid dry powder+Ganoderma (in ganoderan) 20mg; Sodium selenate+cereuisiae fermentum rich in selenoaminoacid (in selenium) 100 μ g; Right amount of auxiliary materials.
19 Ganoderma spore powders+Ganoderma lucidum by submerged culture liquid dry powder (in ganoderan) 10mg; Selenomethionine+selenocarrageenan (in selenium) 150 μ g; Right amount of auxiliary materials.
Below various composition roles are wherein described;
1, Ganoderma has another name called Ganoderma lucidum seu Japonicum, Ganoderma, Ganoderma Lucidum, be Basidiomycetes Polyporaceae Ganoderma Pseudomonas medicine, eat dual-purpose higher fungus.Before more than 2000 years, China's medicine monograph Shennong's Herbal is the earliest just classified Ganoderma as " top grade in the medicine ", but promptly takes life lengthening for a long time, and it is not old to make light of one's life by commiting suicide, effectively nontoxic.Among the people more spreading manyly cured all kinds of diseases and ailments, the magical legend of coming back to life about Ganoderma.
Modern pharmacology studies show that Ganoderma extract has regulating action to human immunocyte or immune factor, immunocompetence that can enhancing body.The extract of different quality Ganodermas all can have activation to macrophage, and Ganoderma extract all has the obvious suppression effect to tumor cell.Ganoderma extract acts on peripheral blood lymphocyte and has the short IL-6 effect that induces, and detects carry out double labelling through PHA (phytohemagglutinin) activated T cell subsets, found that to cause CD4
+Cell proportion increases, and shows the immunological enhancement effect, illustrates that Ganoderma extract can strengthen the immunologic function of normal body.With the isolating ganoderan of hot water extraction Lewis lung cancer and colon cancer are had quite high inhibition growth activity from Ganoderma sporophore, and can strengthen normal mouse peritoneal macrophage phagocytosis and tumor-bearing mice NK cytoactive, thus the human body immunity improving function.Ganoderma extract can strengthen immune function of mice.Ganoderma can as chronic hepatitis, tumor, diabetes and chronic bronchitis etc., have good therapeutic effect because of its good enhance immunity effect to multiple disease in clinical.
2, selenium is one of important trace element of needed by human body, and the intravital selenium overwhelming majority of people is a selenium protein with protein bound, and wherein important have glutathion peroxidase, iodine thyronine take off iodine enzyme, sulfur ammonia also albumen reductase, selenium protein P etc.Selenium plays anti-oxidation function in body, some selenoenzyme is by eliminating the pathogenic effects of lipid peroxidation blocking-up active oxygen and free radical.Selenium almost is present in all immunocytes, and Selenium Supplement is the human body immunity improving ability obviously.
A large amount of clinical researches proof selenium can enhancing body immunocompetence.Show that through experiment in vitro selenium produces IL-2 ability and lymphocyte to the reactive influence of IL-2 to normal person's lymhocyte transformation rate, lymphocyte.The result shows that selenium can strengthen the human lymphocyte conversion ratio, lymphocyte produces the IL-2 ability, but can not improve lymphocyte to the IL-2 reactivity.Prompting selenium can strengthen human immune system's function by strengthening lymphocyte generation IL-2 ability.The operating personnel of nearly hundred pyrometallurgical smelting nickel being tried is divided into selenium supplement (125 μ g/d) and selenium supplement matched group, respectively before selenium supplement, measure peripheral blood WBC sum, classification, the non-specific ester enzyme positive (ANAE after selenium supplement half a year and 1 year
+) cell %, T lymphocyte CD
2 +And subgroup CD
4 +, CD
8 +And CD
4 +/ CD
8 +Ratio.Selenium supplement after 1 year with corresponding selenium supplement matched group ratio, These parameters has to be improved or recovers, the prompting selenium supplement reduces the effect that rise is arranged to the T cell % that is engaged in the nickel operating personnel continuously, in addition to t lymphocyte subset group CD
8 +And CD
4 +/ CD
8 +The increase and decrease of ratio also has regulating action, makes its subgroup proportion of composing be tending towards normal.By being added 500 μ g selenium every day, gastrointestinal cancer patients before the art can make patient NK cytoactive obviously improve CD
3 +, CD
4 +, CD
8 +And CD
4 +/ CD
8 +Ratio is kept normal level, and matched group then obviously descends, and illustrates that selenium supplement can improve the immunocompetence of patient's body really.
3, studies show that, in Ganoderma lucidum by submerged culture liquid, add the Se-rich lucid ganoderma that sodium selenite is cultivated out, wherein selenium content is 4.32mg/g, just can play good enhance immunity effect for mouse stomach with 200mg/kg.bw/d, illustrate that Ganoderma and selenic combination can play the enhance immunity effect better, have synergism.In fact contain plurality of active ingredients such as polysaccharide in the Ganoderma and can both play the enhance immunity effect body, and selenium is the ingredient of glutathione peroxidase, transmit electronics in metabolism, selenium is again a kind of immunological adjuvant, and it is scientific and reasonable therefore both being combined use.
Claims (5)
1, a kind of health product and medicine that comprises Ganoderma and selenium composition, it is characterized in that: this product in each unit mainly by combining the intake that described unit allows for the adult every day in the Ganoderma of ganoderan 0.15mg～15000mg with in the selenium of selenium 0.004 μ g～400 μ g.
2, comprise Ganoderma and selenic health product and medicine according to claim 1, it is characterized in that: Ganoderma is one or more in the full powder of Ganoderma, Ganoderma spore powder, Ganoderma extract, Ganoderma lucidum by submerged culture liquid and the Ganoderma lucidum by submerged culture liquid dry powder; Selenium is one or more in selenocarrageenan, cereuisiae fermentum rich in selenoaminoacid, selenocysteine, sodium selenite, sodium selenate, the selenomethionine.
3, comprise Ganoderma and selenic health product and medicine according to claim 1, it is characterized in that the dosage form of these health product and medicine is: a kind of in oral liquid, tablet, hard capsule, soft capsule, electuary, medicated wine, injection, syrup, the unguentum.
4, as described in claim 3, comprise Ganoderma and selenic health product and medicine, it is characterized in that: these health product and medicine also contain and manufacture the required adjuvant of various dosage forms, and this adjuvant comprises one or more in microcrystalline Cellulose, maltodextrin, cane sugar powder, mannitol, ethanol, arabic gum, gelatin, Macrogol 4000, sodium carboxymethyl cellulose, polyvinylpyrrolidone, carboxymethylstach sodium, magnesium stearate, starch, xylitol, potassium sorbate, Tween 80, sodium pyrosulfite, the simple syrup.
5, comprise Ganoderma and selenic medicine of health products according to claim 1, it is characterized in that: when the adult uses this product, selenic every day, intake the highlyest was no more than 400 μ g/ days, minimum being not less than 0.004 μ g/ days, intake every day of ganoderan is the highest to be no more than 15000mg/ days, minimum being not less than 0.15mg/ days.
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|---|---|---|---|
| CN 200610096012 CN1931197A (en) | 2006-09-11 | 2006-09-11 | Health product and medicine containing glossy ganoderma and selenium |
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|---|---|---|---|
| CN 200610096012 CN1931197A (en) | 2006-09-11 | 2006-09-11 | Health product and medicine containing glossy ganoderma and selenium |
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| CN101721435B (en) * | 2009-12-10 | 2012-02-22 | 安徽省康美来大别山生物科技有限公司 | Ganoderma lucidum spore and nano selenium compound and preparation method thereof |
| CN102511815A (en) * | 2012-01-04 | 2012-06-27 | 江西东荣实业集团有限公司 | Selenium-enriched oral solution and preparation method thereof |
| CN102860508A (en) * | 2012-09-28 | 2013-01-09 | 无锡市天赐康生物科技有限公司 | Immunity-enhancing and anti-fatigue health-care food and preparation method thereof |
| CN102987203A (en) * | 2012-12-05 | 2013-03-27 | 无锡市天赐康生物科技有限公司 | Immunity-improving and blood fat-reducing health food and preparation method thereof |
| CN102099461B (en) * | 2007-12-10 | 2013-08-07 | 东方酵母工业株式会社 | Yeast having immunopotentiating effect and food or feed |
| CN103877437A (en) * | 2014-02-25 | 2014-06-25 | 唐国荣 | Anticancer cancer-preventing traditional Chinese medicine |
| CN104543302A (en) * | 2015-01-29 | 2015-04-29 | 青岛中仁保健品科技有限公司 | Selenium enriched ganoderan soft candy and preparation method thereof |
| CN104840652A (en) * | 2015-05-19 | 2015-08-19 | 王进波 | Preparation and application of selenium-containing traditional Chinese medicine preparation capable of accelerating dairy cow antibiotic metabolism |
| CN105901705A (en) * | 2016-04-20 | 2016-08-31 | 南京财经大学 | Compound preparation of edible mushroom polysaccharides and selenium-rich rice protein peptides and preparation method thereof |
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| CN106993800A (en) * | 2016-01-24 | 2017-08-01 | 赵伟 | Selenium-rich ganoderma spove powder production method |
| CN107006840A (en) * | 2017-02-23 | 2017-08-04 | 北京众康生物科技有限公司 | A kind of Saussurea involucrata culture capsule and preparation method thereof |
| CN107115353A (en) * | 2017-06-26 | 2017-09-01 | 济源希健生物医药科技发展有限公司 | A kind of coriolan of the methylselenocysteinefrom containing L and preparation method thereof |
| CN107951035A (en) * | 2016-10-17 | 2018-04-24 | 马岱瑶 | The technology of the serial selenium-rich health-oriented products of production |
| CN108450958A (en) * | 2018-02-02 | 2018-08-28 | 昆明朗盛生物科技有限公司 | A kind of application of selenium-rich composition and preparation |
| CN108853152A (en) * | 2018-09-21 | 2018-11-23 | 贵州灵康士生物科技有限公司 | A kind of rare edible and medical fungi capsule of compound and preparation method thereof |
| CN109329897A (en) * | 2018-10-19 | 2019-02-15 | 中南大学 | A kind of adjuvant treatment food compositions and preparation method thereof for cancer |
| CN114711420A (en) * | 2022-03-25 | 2022-07-08 | 河南省汉帝药业有限公司 | Composition of health-care product capsule and its production method |
| CN115192539A (en) * | 2022-03-03 | 2022-10-18 | 江西德致生物科技有限公司 | Wall-broken ganoderma lucidum spore powder capsule and preparation method thereof |
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2006
- 2006-09-11 CN CN 200610096012 patent/CN1931197A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102099461B (en) * | 2007-12-10 | 2013-08-07 | 东方酵母工业株式会社 | Yeast having immunopotentiating effect and food or feed |
| CN101721435B (en) * | 2009-12-10 | 2012-02-22 | 安徽省康美来大别山生物科技有限公司 | Ganoderma lucidum spore and nano selenium compound and preparation method thereof |
| CN102511815A (en) * | 2012-01-04 | 2012-06-27 | 江西东荣实业集团有限公司 | Selenium-enriched oral solution and preparation method thereof |
| CN102860508A (en) * | 2012-09-28 | 2013-01-09 | 无锡市天赐康生物科技有限公司 | Immunity-enhancing and anti-fatigue health-care food and preparation method thereof |
| CN102987203A (en) * | 2012-12-05 | 2013-03-27 | 无锡市天赐康生物科技有限公司 | Immunity-improving and blood fat-reducing health food and preparation method thereof |
| CN103877437A (en) * | 2014-02-25 | 2014-06-25 | 唐国荣 | Anticancer cancer-preventing traditional Chinese medicine |
| CN104543302A (en) * | 2015-01-29 | 2015-04-29 | 青岛中仁保健品科技有限公司 | Selenium enriched ganoderan soft candy and preparation method thereof |
| CN104840652A (en) * | 2015-05-19 | 2015-08-19 | 王进波 | Preparation and application of selenium-containing traditional Chinese medicine preparation capable of accelerating dairy cow antibiotic metabolism |
| CN106993800A (en) * | 2016-01-24 | 2017-08-01 | 赵伟 | Selenium-rich ganoderma spove powder production method |
| CN105901705A (en) * | 2016-04-20 | 2016-08-31 | 南京财经大学 | Compound preparation of edible mushroom polysaccharides and selenium-rich rice protein peptides and preparation method thereof |
| CN106036883A (en) * | 2016-06-01 | 2016-10-26 | 南京财经大学 | Toxicity-removing composite tablets containing selenoprotein and glossy ganoderma components and preparation method of toxicity-removing composite tablets |
| CN107951035A (en) * | 2016-10-17 | 2018-04-24 | 马岱瑶 | The technology of the serial selenium-rich health-oriented products of production |
| CN107006840A (en) * | 2017-02-23 | 2017-08-04 | 北京众康生物科技有限公司 | A kind of Saussurea involucrata culture capsule and preparation method thereof |
| CN107115353A (en) * | 2017-06-26 | 2017-09-01 | 济源希健生物医药科技发展有限公司 | A kind of coriolan of the methylselenocysteinefrom containing L and preparation method thereof |
| CN108450958A (en) * | 2018-02-02 | 2018-08-28 | 昆明朗盛生物科技有限公司 | A kind of application of selenium-rich composition and preparation |
| CN108853152A (en) * | 2018-09-21 | 2018-11-23 | 贵州灵康士生物科技有限公司 | A kind of rare edible and medical fungi capsule of compound and preparation method thereof |
| CN109329897A (en) * | 2018-10-19 | 2019-02-15 | 中南大学 | A kind of adjuvant treatment food compositions and preparation method thereof for cancer |
| CN115192539A (en) * | 2022-03-03 | 2022-10-18 | 江西德致生物科技有限公司 | Wall-broken ganoderma lucidum spore powder capsule and preparation method thereof |
| CN114711420A (en) * | 2022-03-25 | 2022-07-08 | 河南省汉帝药业有限公司 | Composition of health-care product capsule and its production method |
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