CN1930284A - 传染性囊病病毒抗原分离株和疫苗 - Google Patents
传染性囊病病毒抗原分离株和疫苗 Download PDFInfo
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- CN1930284A CN1930284A CNA200580008040XA CN200580008040A CN1930284A CN 1930284 A CN1930284 A CN 1930284A CN A200580008040X A CNA200580008040X A CN A200580008040XA CN 200580008040 A CN200580008040 A CN 200580008040A CN 1930284 A CN1930284 A CN 1930284A
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- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
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Abstract
Description
病毒 | 222 | 249 | 254 | 286 | 318 | 321 | 322 | 323 |
经典-STC | P | Q | G | T | G | A | G | D |
特拉华E | T | K | S | I | D | A | G | E |
GLS | T | K | S | T | G | E | G | D |
Rs593 | T | K | N | I | G | A | E | D |
28-1 | T | K | S | I | D | A | G | D |
特拉华A | Q | K | S | I | D | A | G | D |
测试日期 | 活性 |
0 | 4周时的适当经疫苗接种组 |
24 | 对每疫苗组中的15只鸟和未经疫苗接种组中的20只鸟进行放血。 |
28 | 用IBDV攻击分离株对适当组进行攻击 |
38 | 测定囊与体重的比率。 |
组 | 处理 | 途径/体积 | 攻击 | #鸟类编号 |
A | Chicklet Lukert+S21 | IM/0.01mL | 参看下文攻击过程 | 45 |
B | 只有Lukert ACL | IM/0.01mL | 参看下文 | 45 |
C | Lukert ACL+S21 | IM/0.01mL | 参看下文 | 45 |
D | Lukert ACL+28-1 | IM/0.01mL | 参看下文 | 45 |
E | Lukert ACL+15-4 | IM/0.01mL | 参看下文 | 45 |
F | Lukert ACL+Ark Provent | IM/0.01mL | 参看下文 | 45 |
H | 竞争子产物 | IM/0.01mL | 参看下文 | 45 |
I | 攻击对照 | N/a | 参看下文 | 45 |
J | 正常对照 | N/a | n/a | 15 |
攻击分离株 | 剂量/投药 | 攻击流程 |
舍尔顿21 | 对每组的15只鸟投与103.5EID50/0.03mL的滴眼剂 | 在疫苗接种后28天时进行一次 |
变体E | 对每组的15只鸡投与103.5EID50/0.03mL的滴眼剂 | 在疫苗接种后28天时进行一次 |
AL2 | 对每组的15只鸡投与103.5EID50/0.03mL的滴眼剂 | 在疫苗接种后28天时进行一次 |
处理 | ELISA应答 | SN应答 | ||
几何平均滴定量* | 阳性% | 几何平均滴定量 | 阳性% | |
Chicklet Luken+S21 | 15a,b | 0%(0/15) | 1 | 7%(1/15) |
仅含LukertACL | 5a | 7%(1/15) | 1 | 13%(2/15) |
Lukert ACL+S21 | 32b | 0%(0/15) | 2 | 13%(2/15) |
Lukert ACL+28-1 | 589d | 60%(9/15) | 4 | 33%(5/15) |
Lukert ACL+15-4 | 66c | 20%(3/15) | 4 | 33%(5/15) |
Lukert ACL+ArkProvent | 32b | 20%(3/15) | 1 | 7%(1/15) |
竞争子 | 491d | 73%(11/15) | 23 | 73%(11/15) |
攻击对照 | 27b | 0%(0/15) | 1 | 0%(0/15) |
正常对照 | 10a,b,c | 0%(0/5) | 1 | 0%(0/5) |
处理 | 平均组B/Bw比率* | |||
攻击菌株 | 所有组合攻击 | |||
S-21 | 变体E | AL-2 | ||
Chicklet Lukert+S21 | 0.92a | 1.11a | 0.97a,b | 1.00a |
仅含Lukert ACL | 0.96a | 1.16a,b,c | 0.96a | 1.03a |
Lukert ACL+S21 | 1.06a,b | 0.98a | 1.02a,b | 1.02a |
Lukert ACL+28-1 | 1.17a,b,c | 2.24d | 1.77c | 1.73c |
Lukert ACL+15-4 | 1.40b,c | 1.52b,c | 1.04a,b | 1.32b |
Lukert ACL+ArkProvent | 1.01a,b | 1.03a | 0.88a | 0.97a |
竞争子 | 1.49c | 1.62b,c | 1.44b,c | 1.52b,c |
攻击对照 | 0.90a | 0.99a | 1.01a,b | 0.97a |
正常对照 | 4.17d | 4.17e | 4.17d | 4.17d |
处理 | 受保护百分比* | |||
攻击菌株 | 所有组合攻击 | |||
S-21 | 变体E | AL-2 | ||
Chicklet Lukert+S21 | 0 | 0 | 0 | 0 |
仅含Lukert ACL | 0 | 7 | 0 | 2 |
Lukert ACL+S21 | 7 | 7 | 0 | 4 |
Lukert ACL+28-1 | 7 | 60 | 27 | 31 |
Lukert ACL+15-4 | 13 | 13 | 0 | 9 |
Lukert ACL +ArkProvent | 7 | 7 | 0 | 4 |
竞争子 | 20 | 13 | 13 | 16 |
攻击对照 | 0 | 0 | 0 | 0 |
正常对照 | n/a | n/a | n/a | 100 |
Claims (18)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55298904P | 2004-03-12 | 2004-03-12 | |
US60/552,989 | 2004-03-12 | ||
PCT/US2005/007879 WO2005089795A2 (en) | 2004-03-12 | 2005-03-10 | Infectious bursal disease virus antigenic isolates and vaccines |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1930284A true CN1930284A (zh) | 2007-03-14 |
CN1930284B CN1930284B (zh) | 2010-06-23 |
Family
ID=34994418
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200580008040XA Active CN1930284B (zh) | 2004-03-12 | 2005-03-10 | 传染性囊病病毒抗原分离株和疫苗 |
Country Status (17)
Country | Link |
---|---|
US (3) | US7338661B2 (zh) |
EP (2) | EP2272949A3 (zh) |
JP (1) | JP4845874B2 (zh) |
KR (1) | KR101172921B1 (zh) |
CN (1) | CN1930284B (zh) |
AR (1) | AR048429A1 (zh) |
AU (1) | AU2005222604B2 (zh) |
BR (1) | BRPI0508660A (zh) |
CA (1) | CA2557844C (zh) |
CL (1) | CL2010001175A1 (zh) |
CO (1) | CO5721019A2 (zh) |
ES (1) | ES2608599T3 (zh) |
IL (1) | IL177903A (zh) |
MX (1) | MXPA06010377A (zh) |
NZ (1) | NZ549687A (zh) |
WO (1) | WO2005089795A2 (zh) |
ZA (1) | ZA200607609B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109152829A (zh) * | 2016-06-02 | 2019-01-04 | 硕腾服务有限责任公司 | 针对传染性支气管炎的疫苗 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005222604B2 (en) * | 2004-03-12 | 2011-08-11 | Zoetis Services Llc | Infectious Bursal Disease Virus antigenic isolates and vaccines |
KR101511712B1 (ko) * | 2013-04-03 | 2015-04-13 | 주식회사 카브 | 신규 전염성 f낭병 바이러스 ibd k7주 및 이를 이용한 전염성 f낭병 백신 |
CN108126191B (zh) * | 2016-12-01 | 2021-04-06 | 普莱柯生物工程股份有限公司 | 一种疫苗组合物及其制备方法和应用 |
CN108653724B (zh) * | 2017-04-01 | 2020-11-27 | 普莱柯生物工程股份有限公司 | 一种用于预防禽减蛋综合征的疫苗组合物、及其制备方法和应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4530831A (en) * | 1982-11-02 | 1985-07-23 | Akzo N.V. | Infectious Bursal Disease vaccine |
US6471962B1 (en) | 1987-06-14 | 2002-10-29 | The University Of Maryland | Monoclonal antibodies for infectious bursal disease, vaccines and assays for use therewith |
US5192539A (en) | 1988-07-21 | 1993-03-09 | Akzo N.V. | Infectious bursal disease virus production in continuous cell lines |
US5614409A (en) * | 1989-05-30 | 1997-03-25 | Commonwealth Scientific And Industrial Research Organisation | Production of IBDV VP2 in highly immunogenic form |
US5919461A (en) | 1989-10-18 | 1999-07-06 | Akzo Nobel N.V. | Nonpathogenic infectious bursal disease virus and vaccine |
NZ235474A (en) | 1989-10-18 | 1992-12-23 | Univ Maryland | Virus capable of inducing infectious bursal disease; assay and vaccine |
US5595912A (en) * | 1990-05-04 | 1997-01-21 | University Of Maryland College Park | Specific DNA and RNA sequences associated with US IBDV variants, vector carrying DNA sequences, host carrying cloned vector, deduced amino acid sequences, vaccine and method of vaccination |
WO1991016925A1 (en) * | 1990-05-04 | 1991-11-14 | University Of Maryland At College Park | Specific dna sequences related to an ibdv protein including vectors, hosts and vaccines |
IL103939A (en) | 1992-12-01 | 1996-09-12 | Abic Ltd | An anti-DBI vaccine in birds containing attenuated live DBI virus |
US5605792A (en) * | 1993-11-04 | 1997-02-25 | The Ohio State University Research Foundation | Infectious bursal disease virus VP2 fusion protein expressed by baculovirus, use as diagnostic |
US5788970A (en) * | 1994-03-29 | 1998-08-04 | The University Of Maryland College Park | Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon |
CN1202378A (zh) * | 1997-06-02 | 1998-12-23 | 财团法人化学及血清疗法研究所 | 使用细胞系来制备传染性囊病病毒及禽呼肠病毒的方法 |
US6159472A (en) * | 1998-11-16 | 2000-12-12 | Akzo Nobel N.V. | Intradermal Avian immunization with inactivated vaccines |
US6764684B2 (en) * | 2001-09-28 | 2004-07-20 | Zeon Corporation | Avian herpesvirus-based recombinant infectious bursal disease vaccine |
EP1483287A1 (en) * | 2002-03-01 | 2004-12-08 | Akzo Nobel N.V. | An infectious bursal disease virus variant |
MXPA05010113A (es) * | 2003-03-24 | 2005-11-23 | Akzo Nobel Nv | Vacunas y mutantes del virus de enfermedad infecciosa bursal. |
AU2005222604B2 (en) * | 2004-03-12 | 2011-08-11 | Zoetis Services Llc | Infectious Bursal Disease Virus antigenic isolates and vaccines |
-
2005
- 2005-03-10 AU AU2005222604A patent/AU2005222604B2/en active Active
- 2005-03-10 ES ES05732938.5T patent/ES2608599T3/es active Active
- 2005-03-10 CN CN200580008040XA patent/CN1930284B/zh active Active
- 2005-03-10 EP EP10182441A patent/EP2272949A3/en not_active Withdrawn
- 2005-03-10 EP EP05732938.5A patent/EP1722814B1/en active Active
- 2005-03-10 JP JP2007502981A patent/JP4845874B2/ja active Active
- 2005-03-10 US US11/076,713 patent/US7338661B2/en active Active
- 2005-03-10 MX MXPA06010377A patent/MXPA06010377A/es active IP Right Grant
- 2005-03-10 NZ NZ549687A patent/NZ549687A/en unknown
- 2005-03-10 CA CA2557844A patent/CA2557844C/en active Active
- 2005-03-10 BR BRPI0508660-4A patent/BRPI0508660A/pt not_active Application Discontinuation
- 2005-03-10 WO PCT/US2005/007879 patent/WO2005089795A2/en active Application Filing
- 2005-03-10 KR KR1020067021027A patent/KR101172921B1/ko active IP Right Grant
- 2005-03-11 AR ARP050100954A patent/AR048429A1/es not_active Application Discontinuation
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- 2006-09-05 IL IL177903A patent/IL177903A/en active IP Right Grant
- 2006-09-11 ZA ZA200607609A patent/ZA200607609B/en unknown
- 2006-09-12 CO CO06091380A patent/CO5721019A2/es unknown
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2007
- 2007-06-08 US US11/811,222 patent/US20080193480A1/en not_active Abandoned
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2010
- 2010-10-26 CL CL2010001175A patent/CL2010001175A1/es unknown
- 2010-10-28 US US12/914,591 patent/US8323658B2/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109152829A (zh) * | 2016-06-02 | 2019-01-04 | 硕腾服务有限责任公司 | 针对传染性支气管炎的疫苗 |
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Publication number | Publication date |
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WO2005089795A3 (en) | 2006-02-23 |
US20050266019A1 (en) | 2005-12-01 |
AU2005222604B2 (en) | 2011-08-11 |
IL177903A (en) | 2015-04-30 |
CA2557844C (en) | 2016-06-21 |
JP2007528900A (ja) | 2007-10-18 |
US20080193480A1 (en) | 2008-08-14 |
MXPA06010377A (es) | 2007-02-14 |
CA2557844A1 (en) | 2005-09-29 |
CO5721019A2 (es) | 2007-01-31 |
EP2272949A3 (en) | 2011-01-19 |
IL177903A0 (en) | 2006-12-31 |
NZ549687A (en) | 2008-08-29 |
WO2005089795A2 (en) | 2005-09-29 |
US7338661B2 (en) | 2008-03-04 |
AU2005222604A1 (en) | 2005-09-29 |
EP2272949A2 (en) | 2011-01-12 |
EP1722814A2 (en) | 2006-11-22 |
KR20060130726A (ko) | 2006-12-19 |
CN1930284B (zh) | 2010-06-23 |
KR101172921B1 (ko) | 2012-08-13 |
BRPI0508660A (pt) | 2007-08-14 |
US20110123560A1 (en) | 2011-05-26 |
CL2010001175A1 (es) | 2011-04-08 |
AR048429A1 (es) | 2006-04-26 |
ZA200607609B (en) | 2008-07-30 |
EP1722814B1 (en) | 2016-11-09 |
ES2608599T3 (es) | 2017-04-12 |
JP4845874B2 (ja) | 2011-12-28 |
US8323658B2 (en) | 2012-12-04 |
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