CN1895630A - Chinese medicine for treating apoplexia hemiparalysis, chestache and cardiodynia and its preparation - Google Patents
Chinese medicine for treating apoplexia hemiparalysis, chestache and cardiodynia and its preparation Download PDFInfo
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- CN1895630A CN1895630A CNA2006100468322A CN200610046832A CN1895630A CN 1895630 A CN1895630 A CN 1895630A CN A2006100468322 A CNA2006100468322 A CN A2006100468322A CN 200610046832 A CN200610046832 A CN 200610046832A CN 1895630 A CN1895630 A CN 1895630A
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- scolopendra
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- 239000003814 drug Substances 0.000 title claims abstract description 10
- 206010008479 Chest Pain Diseases 0.000 title 1
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 7
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 7
- 206010019468 Hemiplegia Diseases 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims abstract description 4
- 239000000463 material Substances 0.000 claims abstract description 3
- 239000009636 Huang Qi Substances 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 241000972155 Moschus Species 0.000 claims description 6
- 241000131808 Scolopendra Species 0.000 claims description 6
- 241000522620 Scorpio Species 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000009490 scorpio Substances 0.000 claims description 6
- 241000489492 Arisaema Species 0.000 claims description 3
- 241000756943 Codonopsis Species 0.000 claims description 3
- 210000000941 bile Anatomy 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 210000000582 semen Anatomy 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 210000000115 thoracic cavity Anatomy 0.000 claims description 3
- 239000000047 product Substances 0.000 claims description 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 244000124209 Crocus sativus Species 0.000 abstract 1
- 241000219780 Pueraria Species 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- -1 astragalus root Substances 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 235000013974 saffron Nutrition 0.000 abstract 1
- 239000004248 saffron Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 208000026106 cerebrovascular disease Diseases 0.000 description 4
- 230000002526 effect on cardiovascular system Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 208000024172 Cardiovascular disease Diseases 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 2
- 208000031226 Hyperlipidaemia Diseases 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 101710145505 Fiber protein Proteins 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 102000018120 Recombinases Human genes 0.000 description 1
- 108010091086 Recombinases Proteins 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000007953 anoxia Effects 0.000 description 1
- 230000003257 anti-anginal effect Effects 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 229940124345 antianginal agent Drugs 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940030600 antihypertensive agent Drugs 0.000 description 1
- 239000002220 antihypertensive agent Substances 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 235000006486 human diet Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 210000001178 neural stem cell Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
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- Marine Sciences & Fisheries (AREA)
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- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Alternative & Traditional Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Medicines Containing Plant Substances (AREA)
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Abstract
A Chinese medicine for preventing and treating apoplexy hemiplegia, qi obstruction of chest and cardialgia is prepared from 19 Chinese-medicinal materials including astragalus root, saffron, notoginseng, pueraria root, etc. Its preparing process is also disclosed.
Description
Technical field
A kind of apoplectic hemiplegia, the thoracic obstruction, pained Chinese medicine and production method of being used for the treatment of.
Background technology
Along with the continuous variation of human diet and rhythm of life, the cardiovascular and cerebrovascular vessel sickness rate constantly increases.Because three-hypers body constitution is the basic pathological changes that causes cardiovascular and cerebrovascular disease to have jointly, especially in mid-aged population, sickness rate improves constantly socially for Gu Er, cardiovascular and cerebrovascular disease, even rank first of the dead disease of middle-aged and elderly people, the serious threat mankind's life is with healthy.
The Chinese medicine that the above-mentioned disease of multiple treatment was arranged in the past, but prescription is at the symptom administration after the morbidity mostly, does not relate to pathogeny, exists therapeutic effect poor, shortcoming such as price comparison height.
Summary of the invention
The objective of the invention is to have jointly the basic cause of disease and the hyperlipidemia of " three-hypers body constitution " according to cardiovascular and cerebrovascular disease, hypertension, high blood viscosity and atheroma pathogeny, employing has the Chinese medicine of " benefiting QI for activating blood circulation; disperse blood stasis and dredge collateral " function, reasonable formula, make and have three and fall: promptly 1 falls hyperlipidemia, 2 antihypertensives, 3 fall the formation of high blood viscosity and atheromatous plaque, six is anti-: i.e. the formation of 1 anti-platelet aggregation and inside and outside thrombosis, 2 anti-cerebral ischemias, 3 encephaledemas and cerebral infarction, 4 anoxias that resist myocardial ischemia, generation (the CPK of 5 anti-myocardium enzyme, LDH), 6 antianginals and arrhythmia, three activate: i.e. 1 activity that activates superoxide dismutase (SOD), the activity of 2 activation fiber protein resolvases, medicinal characteristics such as 3 activation endogenous neural stem cells, safety non-toxic, quality controllable, the Chinese medicine of determined curative effect.
The component of the present invention's prescription is as follows:
Radix Astragali 12-15% Stigma Croci 7-9% Radix Notoginseng 7-9%
Radix Puerariae 7-9% Rhizoma Chuanxiong 7-9% Rhizoma Gastrodiae 4-6%
Borneolum Syntheticum 1-2% Scorpio 1-2% Scolopendra 1-2%
Artificial Moschus 0.01-0.03% artificial Calculus Bovis 0.3-0.7%
Radix Codonopsis 9-12% Radix Salviae Miltiorrhizae 4-6% Radix Curcumae 4-6%
Radix Polygoni Multiflori Preparata 4-6% Concha Haliotidis 4-6% Caulis Spatholobi 4-6%
Semen Persicae 4-6% Arisaema Cum Bile 2-4%
After making finished product with above materials of weight proportions, each become grouping and final proportioning should be 100%;
Manufacture method of the present invention is as follows: the Radix Astragali 10.6%; Stigma Croci; Radix Notoginseng; Radix Puerariae; Rhizoma Chuanxiong; Rhizoma Gastrodiae; Borneolum Syntheticum; Scorpio; Scolopendra; the artificial Moschus; the artificial Calculus Bovis is ground into 100-300 order fine powder; the residue Radix Astragali and all the other components decoct with water three times; for the first time adding water 8-10 doubly measures; decocted 1-3 hour; second; respectively adding water 7-10 three times doubly measures; decocted 1-2 hour; merge three times decocting liquid; filter; filtrate natural simmer down to relative density under 40 ℃ of-60 ℃ of temperature is 1.30 thick paste; add above-mentioned detailed powder again; physics stirs evenly, and under 30 ℃ of-50 ℃ of temperature dry 20-28 hour, is ground into 20 order fine powders; add 75% ethanol again, make diameter 1-3mm feed particles and get final product.
Compare with the Chinese medicine of the above-mentioned disease of existing treatment with the Chinese medicine that the present invention makes, because the present invention starts with from pathogeny, from human body integral, adopt dialectical executing to control prescription, in line with treating both the principal and secondary aspects of a disease, the principle that treatment combines with prevention, Gu Er, have short treating period, instant effect, cure rate height, healing and afterwards be difficult for characteristics such as recurring, have no side effect, conspicuous promotional value is arranged.
The specific embodiment
The present invention will be further described now to lift an example: the component of example formulations of the present invention is as follows:
The Radix Astragali 13.2% Stigma Croci 8% Radix Notoginseng 8%
Radix Puerariae 8% Rhizoma Chuanxiong 8% Rhizoma Gastrodiae 5.2%
Borneolum Syntheticum 1.3% Scorpio 1.3% Scolopendra 1.4%
Artificial Moschus 0.03% artificial Calculus Bovis 0.53%
Radix Codonopsis 10.24% Radix Salviae Miltiorrhizae 5.3% Radix Curcumae 5.3%
Radix Polygoni Multiflori Preparata 5.3% Concha Haliotidis 5.3% Caulis Spatholobi 5.3%
Semen Persicae 5.3% Arisaema Cum Bile 3%
The manufacture method of example of the present invention is as follows: the Radix Astragali 10.6%; Stigma Croci; Radix Notoginseng; Radix Puerariae; Rhizoma Chuanxiong; Rhizoma Gastrodiae; Borneolum Syntheticum; Scorpio; Scolopendra; the artificial Moschus; the artificial Calculus Bovis is ground into 250 order fine powders; the residue Radix Astragali and all the other components decoct with water three times; add for the first time 9 times of amounts of water; decocted 2 hours; second; respectively add 8 times of amounts of water for three times; decocted 1.5 hours; merge three times decocting liquid; filter; filtrate natural simmer down to relative density under 50 ℃ of temperature is 1.30 thick paste, adds above-mentioned detailed powder again, and physics stirs evenly; drying is 24 hours under 50 ℃ of temperature; be ground into 20 order fine powders, add 75% ethanol again, make diameter 2mm feed particles; be pressed into 0.62 gram/sheet, the bag film-coat gets final product.
Claims (1)
1, a kind of apoplectic hemiplegia, the thoracic obstruction, pained Chinese medicine and production method of being used for the treatment of is characterized in that the component of filling a prescription is as follows:
Radix Astragali 12-15% Stigma Croci 7-9% Radix Notoginseng 7-9%
Radix Puerariae 7-9% Rhizoma Chuanxiong 7-9% Rhizoma Gastrodiae 4-6%
Borneolum Syntheticum 1-2% Scorpio 1-2% Scolopendra 1-2%
Artificial Moschus 0.01-0.03% artificial Calculus Bovis 0.3-0.7%
Radix Codonopsis 9-12% Radix Salviae Miltiorrhizae 4-6% Radix Curcumae 4-6%
Radix Polygoni Multiflori Preparata 4-6% Concha Haliotidis 4-6% Caulis Spatholobi 4-6%
Semen Persicae 4-6% Arisaema Cum Bile 2-4%
After making finished product with above materials of weight proportions, each become grouping and final proportioning should be 100%; Manufacture method of the present invention is as follows: the Radix Astragali 10.6%; Stigma Croci; Radix Notoginseng; Radix Puerariae; Rhizoma Chuanxiong; Rhizoma Gastrodiae; Borneolum Syntheticum; Scorpio; Scolopendra; the artificial Moschus; the artificial Calculus Bovis is ground into 100-300 order fine powder; the residue Radix Astragali and all the other components decoct with water three times; for the first time adding water 8-10 doubly measures; decocted 1-3 hour; second; respectively adding water 7-10 three times doubly measures; decocted 1-2 hour; merge three times decocting liquid; filter; filtrate natural simmer down to relative density under 40 ℃ of-60 ℃ of temperature is 1.30 thick paste; add above-mentioned detailed powder again; physics stirs evenly, and under 30 ℃ of-50 ℃ of temperature dry 20-28 hour, is ground into 20 order fine powders; add 75% ethanol again, make diameter 1-3mm feed particles and get final product.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100468322A CN100379445C (en) | 2006-06-07 | 2006-06-07 | Chinese medicine for treating apoplexia hemiparalysis, chestache and cardiodynia and its preparation |
| CH00847/07A CH699627B1 (en) | 2006-06-07 | 2007-05-29 | Composition of Chinese medicinal herbs for treating apoplexy, hemiplegia, myocardial ischemia and Kardiodynie, and processes for their preparation. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100468322A CN100379445C (en) | 2006-06-07 | 2006-06-07 | Chinese medicine for treating apoplexia hemiparalysis, chestache and cardiodynia and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1895630A true CN1895630A (en) | 2007-01-17 |
| CN100379445C CN100379445C (en) | 2008-04-09 |
Family
ID=37608373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100468322A Active CN100379445C (en) | 2006-06-07 | 2006-06-07 | Chinese medicine for treating apoplexia hemiparalysis, chestache and cardiodynia and its preparation |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN100379445C (en) |
| CH (1) | CH699627B1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083473A (en) * | 2011-11-08 | 2013-05-08 | 谢朝云 | Medicament for treating heart disease and preparation method thereof |
| CN104096095A (en) * | 2014-06-27 | 2014-10-15 | 甘保明 | Bezoar wind-dispelling decoction capable of preventing and treating cerebral apoplexy |
| CN104984139A (en) * | 2015-07-28 | 2015-10-21 | 王雄 | Traditional Chinese medicine composition for treating three-hypers |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1259937C (en) * | 2002-04-12 | 2006-06-21 | 淄博市春燕育孤院 | Health nutrient capsule and its preparation and use |
| CN1302805C (en) * | 2005-04-14 | 2007-03-07 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
-
2006
- 2006-06-07 CN CNB2006100468322A patent/CN100379445C/en active Active
-
2007
- 2007-05-29 CH CH00847/07A patent/CH699627B1/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083473A (en) * | 2011-11-08 | 2013-05-08 | 谢朝云 | Medicament for treating heart disease and preparation method thereof |
| CN104096095A (en) * | 2014-06-27 | 2014-10-15 | 甘保明 | Bezoar wind-dispelling decoction capable of preventing and treating cerebral apoplexy |
| CN104984139A (en) * | 2015-07-28 | 2015-10-21 | 王雄 | Traditional Chinese medicine composition for treating three-hypers |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100379445C (en) | 2008-04-09 |
| CH699627B1 (en) | 2010-04-15 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20070117 Assignee: Jilin Yida Biological Technology Co.,Ltd. Assignor: Zhao Guangjun Contract record no.: 2012220000041 Denomination of invention: Chinese medicine for treating apoplexia hemiparalysis, chestache and cardiodynia and its preparation Granted publication date: 20080409 License type: Exclusive License Record date: 20121010 |
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Effective date of registration: 20180508 Address after: 130000 1 gate 901, B7 building, Chaoyang District prosperity Road, Changchun, Jilin. Patentee after: Chen Tiecheng Address before: 132000 2555 Tuen Jie Road, Tonghua, Jilin Patentee before: Zhao Guangjun |
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Effective date of registration: 20220817 Address after: Sanhe Industrial Park, Dongfeng County, Liaoyuan City, Jilin Province, 136300 Patentee after: Jilin Yida Pharmaceutical Co.,Ltd. Address before: 130000 1 gate 901, B7 building, Chaoyang District prosperity Road, Changchun, Jilin. Patentee before: Chen Tiecheng |
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Address after: Sanhe Industrial Park, Dongfeng County, Liaoyuan City, Jilin Province, 136300 Patentee after: Tianchangyuan Pharmaceutical (Jilin) Co.,Ltd. Country or region after: China Address before: Sanhe Industrial Park, Dongfeng County, Liaoyuan City, Jilin Province, 136300 Patentee before: Jilin Yida Pharmaceutical Co.,Ltd. Country or region before: China |
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