CN1895514A - Medicine for treating behcet's syndrome - Google Patents

Abstract

A Chinese medicine for treating Behcet's disease is prepared from 14 Chinese-medicinal materials including China root, coix seed, coptis root, honeysuckle flower, etc.

Description

The medicine of treatment Behcet disease

Technical field

The present invention relates to a kind of Chinese patent medicine for the treatment of Behcet disease.

Background technology

Behcet disease (Behcets ' disease, BD), claim behcet syndrome again, behcet syndrome.While or the oral ulcer that successively takes place and eye, genitals, skin lesion are this sick main clinical characteristics.Also can involve the pathological changes of multisystems such as joint and cardiovascular, nerve, digestion, breathing, urinary system, consequence is serious.Primary disease pain is obvious, influence feed, and the course of disease is longer, and outbreak repeatedly, it is difficult to twine, and also can cause blind, even dead.Have a strong impact on patient's study, work and quality of life.Morbidity in recent years has the trend of increasing.Its definite cause of disease is still indeterminate, but relevant studies show that, factors such as immunity, heredity, and fibrinolytic system, microcirculqtory system obstacle, and infection such as virus, antibacterial, treponema pallidum, trace element deficiencies etc. may be relevant with primary disease.Motherland's medical science is thought that its disease is various, is changed unpredictably, and is called just as " doubt is deluded and confuse " " hu huo syndrome ".At present the treatment doctor trained in Western medicine to Behcet disease adopts adrenocortical hormone, cytotoxic drug, immunostimulant and local treatment such as suit the medicine to the illness; Chinese medicine adopts treatments such as Decoction of Gentiana for Purging the Liver-fire, LIUWEI DIHUANG TANG plus-minus; But exist effect undesirable, long, the easily recurrence course of treatment, toxic and side effects be big, be difficult to shortcoming such as radical cure.

Summary of the invention

The purpose of this invention is to provide a kind of medicine for the treatment of Behcet disease, to solve long, the easy recurrence course of treatment that has treatment Behcet disease medicine now and exist, the problem that toxic and side effects is big.

Medical material in the raw material of the present invention is formed and the weight portion proportioning is:

Rhizoma Smilacis Glabrae 30-50 part, Semen Coicis 30-50 part, Radix Stephaniae Tetrandrae 10-15 part, Rhizoma Coptidis 10-15 part,

Cortex Phellodendri 10-15 part, Flos Lonicerae 15-30 part, Radix Astragali 30-12 part, Radix Achyranthis Bidentatae 10-15 part,

Caulis Spatholobi 30-50 part, Radix Angelicae Sinensis 15-30 part, Radix Salviae Miltiorrhizae 30-50 part, Radix Scrophulariae 15-30 part,

Rhizoma Atractylodis 15-20 part and Radix Glycyrrhizae 10-15 part.

Medical material in the raw material of the present invention is formed and preferred weight part proportioning is:

40 parts of Rhizoma Smilacis Glabraes, 40 parts of Semen Coiciss, 12 parts of Radixs Stephaniae Tetrandrae, 12 parts of Rhizoma Coptidis,

12 parts of Cortex Phellodendris, 20 parts of Flos Loniceraes, 80 parts of Radix Astragali, 12 parts of Radix Achyranthis Bidentataes,

40 parts of Caulis Spatholobis, 20 parts of Radix Angelicae Sinensis, 40 parts of Radix Salviae Miltiorrhizaes, 20 parts of Radix Scrophulariaes,

12 parts in 18 parts of Rhizoma Atractylodis and Radix Glycyrrhizae.

The present invention can be made into water preparation: get the Chinese medicine medical material of above weight ratio part, add an amount of decocting, after the cold of drying in the air, use the plastic bag sealing sterilization packaging, every bag of 300ml.

The present invention also can be made into pill: the Chinese herbal medicine of getting total dose 20% is pulverized, be processed into superfine powder, all the other Chinese herbal medicine of 80% are blended into the duple water of total dose and decoct 12 hours in stainless-steel pans, sieve and remove slag, the medicine juice that filter is good reenters pot and endures and be boiled into poultice in 12 hours, with aforesaid 20% Chinese herbal medicine powder pour in the poultice fully stir after, machine-processed granulating ball.Use plastic bottle packing, per 10 is 5g, 100 every bottle.

The present invention is based on motherland's medical science to pathogenetic understanding of Behcet disease and Therapeutic Principle.The inventor thinks that Behcet disease is that the dampness-heat of the liver multiple abscess is in meridians, due to scorchingly hot inside fire attack, qi depression to blood stasis, liver, the deficiency of the kidney yin.With the plain void of body constitution is basis, and promptly thanks to become estranged be this for spleen, kidney, liver-yin yang-energy blood deficiency, and wet, poison, heat is handed over knot, pented up is to mark.Adopt heat-clearing and toxic substances removing, let out damp and hotly clearly, benefiting vital QI and blood, blood circulation promoting and blood stasis dispelling are principle, giving consideration to both the incidental and fundamental.

Rhizoma Smilacis Glabrae detoxifcation among the present invention, dehumidifying, sharp joint, return liver, stomach through being monarch drug.Semen Coicis, Radix Stephaniae Tetrandrae, Cortex Phellodendri, Rhizoma Coptidis, Flos Lonicerae are strengthened the Rhizoma Smilacis Glabrae heat-clearing and toxic substances removing, dampness removing act as ministerial drug.Radix Salviae Miltiorrhizae, Radix Scrophulariae heat clearing away, invigorate blood circulation, collateral dredging, Caulis Spatholobi, Chinese angelica blood supplementing, yin nourishing, Radix Astragali QI invigorating Yiyang, Radix Achyranthis Bidentatae, Rhizoma Atractylodis dampness, heat clearing away are adjuvant.The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, wherein the Radix Astragali modern medicine thinks to have the immunity of raising, trophic nerve effect, Radix Salviae Miltiorrhizae, Radix Scrophulariae have the effect of expansion blood capillary, microcirculation improvement.

Medicine of the present invention is clinical practice 285 examples.Woman's 196 examples, male 89 examples, minimal ages 18 years old, maximum 65 years old age.The diagnostic criteria that diagnostic criteria adopts nineteen ninety BD international symposium to propose is: based on recurrent oral ulceration, adding following any two can make a definite diagnosis.(1) recurrent genital ulcer; (2) ophthalmic (uveitis, retinitis etc.); (3) skin lesion (erythema nodosum etc.); (4) skin acupuncture reacting positive.Wherein cure 263 examples, effective 14 examples, cure rate reaches 92.3%, effective percentage 97.2%.Average 45 days of the course of treatment.Above case is not seen toxic side effect.

The present invention have cure rate height, short treating period, secure persistent, relapse rate low, have no side effect, treating both the principal and secondary aspects of a disease, economic characteristics.

The specific embodiment

The following examples can make those skilled in the art more fully understand the present invention, but do not limit the present invention in any way.

Embodiment 1

Take by weighing each crude drug by following weight proportion:

Rhizoma Smilacis Glabrae 30g, Semen Coicis 30g, Radix Stephaniae Tetrandrae 10g, Rhizoma Coptidis 10g,

Cortex Phellodendri 10g, Flos Lonicerae 15g, Radix Astragali 30g, Radix Achyranthis Bidentatae 10g,

Caulis Spatholobi 30g, Radix Angelicae Sinensis 15g, Radix Salviae Miltiorrhizae 30g, Radix Scrophulariae 15g,

Rhizoma Atractylodis 15g and Radix Glycyrrhizae 10g,

Add an amount of decocting, pack, make water preparation, every bag of 300ml with plastic bag sealing.Each 1 bag, one day twice, one after each meal.Serve on water preparation 7-15 days.

Embodiment 2

Take by weighing each crude drug by following weight proportion:

Rhizoma Smilacis Glabrae 40g, Semen Coicis 40g, Radix Stephaniae Tetrandrae 12g, Rhizoma Coptidis 12g,

Cortex Phellodendri 12g, Flos Lonicerae 20g, Radix Astragali 80g, Radix Achyranthis Bidentatae 12g,

Caulis Spatholobi 40g, Radix Angelicae Sinensis 20g, Radix Salviae Miltiorrhizae 40g, Radix Scrophulariae 20g,

Rhizoma Atractylodis 18g and Radix Glycyrrhizae 12g,

Add an amount of decocting, pack, make water preparation, every bag of 300ml with plastic bag sealing.Each 1 bag, one day twice, one after each meal.Serve on water preparation 7-15 days.

Embodiment 3

Take by weighing each crude drug by following weight proportion:

Rhizoma Smilacis Glabrae 50g, Semen Coicis 50g, Radix Stephaniae Tetrandrae 15g, Rhizoma Coptidis 15g,

Cortex Phellodendri 15g, Flos Lonicerae 30g, Radix Astragali 120g, Radix Achyranthis Bidentatae 15g,

Caulis Spatholobi 50g, Radix Angelicae Sinensis 30g, Radix Salviae Miltiorrhizae 50g, Radix Scrophulariae 30g,

Rhizoma Atractylodis 20g and Radix Glycyrrhizae 15g,

Getting the Chinese herbal medicine of total dose 20% pulverizes, be processed into superfine powder, all the other Chinese herbal medicine of 80% are blended into the duple water of total dose and decoct 12 hours in stainless-steel pans, sieve and remove slag, the medicine juice that filter is good reenters pot and endures and be boiled into poultice in 12 hours, with aforesaid 20% Chinese herbal medicine powder pour in the poultice fully stir after, machine-processed granulating ball.Use plastic bottle packing, per 10 is 5g, 100 every bottle.When taking concentrated pill, each 10, three times on the one, consolidate the curative effect 1-3 month.

Claims (2)

1, a kind of medicine for the treatment of Behcet disease is characterized in that medical material composition and the weight portion proportioning in the raw material is:

Rhizoma Smilacis Glabrae 30-50 part, Semen Coicis 30-50 part, Radix Stephaniae Tetrandrae 10-15 part, Rhizoma Coptidis 10-15 part,

Cortex Phellodendri 10-15 part, Flos Lonicerae 15-30 part, Radix Astragali 30-12 part, Radix Achyranthis Bidentatae 10-15 part,

Caulis Spatholobi 30-50 part, Radix Angelicae Sinensis 15-30 part, Radix Salviae Miltiorrhizae 30-50 part, Radix Scrophulariae 15-30 part,

Rhizoma Atractylodis 15-20 part and Radix Glycyrrhizae 10-15 part.

2, the medicine of treatment Behcet disease according to claim 1 is characterized in that medical material composition and the weight portion proportioning in the raw material is:

40 parts of Rhizoma Smilacis Glabraes, 40 parts of Semen Coiciss, 12 parts of Radixs Stephaniae Tetrandrae, 12 parts of Rhizoma Coptidis,

12 parts of Cortex Phellodendris, 20 parts of Flos Loniceraes, 80 parts of Radix Astragali, 12 parts of Radix Achyranthis Bidentataes,

40 parts of Caulis Spatholobis, 20 parts of Radix Angelicae Sinensis, 40 parts of Radix Salviae Miltiorrhizaes, 20 parts of Radix Scrophulariaes,

12 parts in 18 parts of Rhizoma Atractylodis and Radix Glycyrrhizae.