CN103690709A - Traditional Chinese medicine for treating intestinal Behcet disease - Google Patents
Traditional Chinese medicine for treating intestinal Behcet disease Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating intestinal Behcet disease. The traditional Chinese medicine is prepared from the following Chinese medicinal herbs in parts by weight: 10 parts of greyhair cipadessa root or leaf, 15 parts of pseudodrynaria coronans, 10 parts of all grass of anderson cirrhopetalum extract, 15 parts of phyllanthus urinaria, 15 parts of Ludwigia hyssopifo-lia (G.Don)Exekk, 9 parts of homlockleaved moonwort, 9 parts of cryptocoryne yunnanensis, 20 parts of pubescent pepper herb, 15 parts of ophioglossum vulgatum, 20 parts of pilea swinglei merr, 10 parts of saussurea arenaria and 15 parts of turnipshaped hawksbeard rootor herb. Clinical experiments prove that the traditional Chinese medicine is capable of safely and effectively treating the intestinal Behcet disease.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of intestinal Behcet disease.
Background technology
Behcet disease (Behcet ' s disease, BD) be a kind of general, chronic, vascular inflammation disease, main clinical manifestation is recurrent oral ulceration, genital ulcer, ophthalmia and skin lesion, also can involve the organs such as blood vessel, nervous system, digestive tract, joint, lung, kidney, epididymis.This disease has certain inherited genetic factors, and the state of an illness is the alternation procedure that repeatedly shows effect and alleviate.Most of patient prognosis bona, and eye, nervus centralis and trunk affected individual prognosis are not good.Behcet disease involves digestive tract ulcer, and person is called gastrointestinal type Behcet disease, that is intestinal Behcet disease.The clinical manifestation of intestinal Behcet disease mostly is stomachache, intestinal ulcer, digestive tract hemorrhage etc.Because of intestinal blood vessel wall fibrinoid degeneration, easily there is ulcer in intestinal, even produces the complication such as intestinal perforation.In recent years, the sickness rate of intestinal Behcet disease raise more in the past.Primary disease there is no at present generally acknowledges effective radical cure method, and multi-medicament is all effective, but mostly recurrence after drug withdrawal.In addition, some side effects of pharmaceutical drugs are larger, further cause other severe complication in the time for the treatment of, more increased the weight of patient's burden.Therefore, research and develop medicine safely and effectively and there is important clinical meaning.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Radix seu folium cipakessae cinerascentis [source] Meliaceae Cipadessa baecifera Miq platymiscium gray wool Cipadessa baecifera Miq Cipadessa cinerascens (Pell.) Hand.-Mazz., is used as medicine with root, leaf.Root can be adopted the whole year, and section is dried.Ye Xiaqiucai, using fresh herb or dry in the shade.[function cures mainly] heat-clearing and toxic substances removing, circulation of qi promoting relieving constipation, preventing the attack (or recurrence) of malaria.For flu, heating is not moved back, malaria, constipation, stomachache, dysentery, rheumatic arthritis; Children's's dermatitis, skin pruritus, burn and scald are controlled in external.
Precipice Rhizoma Zingiberis Recens [source] fern Polypodiaceae precipice ginger precipice Rhizoma Zingiberis Recens Pseudodrynaria coronans (Wall.) Ching, is used as medicine with root stock.Spring and summer gathers, and unhairing is cleaned section, dries.[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatalgia, traumatic injury, fracture, otitis media.
The blue Cirrhopetalnm andersonii of Herba Cirrohopetali Andersonii [source] the orchid family volume lobe epidendrum comb cap volume lobe Hook. f., with all herbal medicine.The four seasons can adopt, using fresh herb or dry.[function cures mainly] expelling wind and removing dampness, invigorates blood circulation, and cough-relieving helps digestion long-pending.For traumatic injury, human female is empty, infantile cough, pertussis.
Cacumen Securinegae Suffruticosae [source] is Euphorbiaceae phyllanthus emblica platymiscium Cacumen Securinegae Suffruticosae Phyllanthus urinaria L., with all herbal medicine.Xia Qiu gathers herb, and decontamination, dries.[function cures mainly] clearing away heat and promoting diuresis, improving eyesight, removing food stagnancy.For oedema due to nephritis, urinary system infection, calculus, enteritis, dysentery, young waiter in a wineshop or an inn's infantile malnutrition, eye keratitis, icterohepatitis; External is controlled Trimeresurus stejnegeri and is bitten.
The imperial root of grass [source] is the root of onagraceae plant line leaf Herba Ludwigiae Prostratae Ludwigia hyssopifo-lia (G.Don) Exell..Excavate autumn, cleans using fresh herb or dry.[function cures mainly] antiasthmatic-antitussive; Removing food stagnancy; Eliminating stagnation.Main asthma; Cough; Infantile malnutrition; Scrofula.
Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. [source] is Botrychiaceae plant Herba pteridii latiusculi beanstalk Botrypus virginianus (L.) Holub[Osmunda virginiana L; Botrychium virginianum (L.) Sw.] root or herb.Excavate spring, cleans, and dries or using fresh herb.[function cures mainly] heat-clearing and toxic substances removing; Suppressing the hyperactive liver eliminating stagnation; Expelling wind for relieving convulsion.Main lung abscess; Venom; Conjunctival congestion; Scrofula; Cough; Serpentis poison; Acute infantile convulsion wind; Rheumatic arthralgia; Traumatic injury.
Herba Cryptocoryne yunnanensis [source] is crossed the herb of cost of living Cryptocoryne yunnanensis H. Li for the aroid Eight Immortals.Summer, autumn gather, and clean, and chopping is dried.[function cures mainly] relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness; Preventing the attack (or recurrence) of malaria.Main traumatic injury; Rheumatic arthralgia; Four skills are numb; Waist knee joint flaccidity is soft; Acute gastroenteritis; Malaria.
White hog snout hole [source] is the herb of the white luxuriant naked capsule Cymnotheca involucrata pei. of Saururaceae plant.Gather summer, wash away silt, using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing; Diuretic.Main lung abscess; Damp-heat vaginal discharge; Nebulousurine; Dysuria; Furuncle toxic swelling.
Herba Ophioglossi [source] is Ophioglossaceae plant Herba Ophioglossi Ophioglossum vulgatum L.[O.nipponicum Miyabe et Kudo] herb.Summer, autumn gather, and clean and dry, or using fresh herb.[function cures mainly] clearing away heat and cooling blood; Analgesia; Removing toxic substances.Main cough due to lung-heat; Over-strained hemoptysis; Lung abscess; Stomachache; Stranguria with turbid discharge; Carbuncle sore tumefacting virus; Snake bite and insect sting; Traumatic injury; Infantile hyperpyrexia infantile convulsion; Conjunctival congestion and swelling pain.
Triangle leaf Rhizoma Belamcandae [source] is the herb of contrayerva triangle leaf Rhizoma Belamcandae Pilea swinglei Merr..All can gather the whole year, cleans using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing; Stasis-dispelling and pain-killing.The swollen carbuncle poison of main furuncle; Venom; Traumatic injury.
Saussurea arenaria Maxim. [source] is the leaf of feverfew Saussurea arenaria Maxim. Saussurea arenaria Maxim..During summer-flowering, gather, clean, dry.[function cures mainly] table wind heat; Removing toxic substances; Hemostasis.Main anemopyretic cold; Skin ulcer is produced and is afraid of carbuncle; Traumatic hemorrhage.
Meat root Radix Crepidis elongatae [source] is root or the herb of feverfew brassica rapa Radix Crepidis elongatae Crepis napifera (Franch.) Babc..Summer, autumn gather, and clean using fresh herb or dry.[function cures mainly] clearing away lung-heat to relieve cough; Nourishing the liver to improve visual acuity.Main cough due to lung-heat; Pertussis; Nyctalopia.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of intestinal Behcet disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing intestinal Behcet disease.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of intestinal Behcet disease, it is characterized in that, by the medical material of following weight proportion, be prepared from: 10 parts of Radix seu folium cipakessae cinerascentiss, 15 parts of precipice Rhizoma Zingiberis Recens, 10 parts of Herba Cirrohopetali Andersoniis, 15 parts of Cacumen Securinegae Suffruticosaes, 15 parts of careless imperial roots, 9 parts of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 9 parts of Herba Cryptocoryne yunnanensis, 20 parts, white hog snout hole, 15 parts of Herba Ophioglossis, 20 parts of triangle leaf Rhizoma Belamcandaes, 10 parts of Saussurea arenaria Maxim., 15 parts of meat root Radix Crepidis elongatae.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
The out-patient that inventor collects 75 routine intestinal Behcet disease between year JIUYUE of June-2011 in 2008 altogether, age 25-60 year, course of disease 1-6.Be divided at random: treatment group 38 examples, matched group 37 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.The January course for the treatment of.
2.2 matched groups adopt conventional therapy, oral prednisone 40-60mg/ days, and after state of an illness control, decrement arrives 10-15mg/ days gradually.The January course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptom disappearance, biochemical indicator inspection is normal.Effective: symptom substantially alleviates or disappears, biochemical indicator checks normal.Effective: symptom alleviates substantially, biochemical indicator inspection alleviates.Invalid: symptom alleviates not obvious.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
| Group | n | Recovery from illness | Effective | Effectively | Invalid | Untoward reaction example | Total effective rate (%) |
| Treatment group | 38 | 6（15.8%） | 18（47.4%) | 8（21.1%） | 6（15.8） | 0 | 84.3% |
| Matched group | 37 | 10（27.0%） | 14(37.8%) | 9（24.3%） | 4（10.8%） | 3（8.1%） | 89.1% |
Visible, the medicine that the present invention makes can safe and effective treatment intestinal Behcet disease.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
specific embodiment 1
Take: 10 grams of Radix seu folium cipakessae cinerascentiss, 15 grams of precipice Rhizoma Zingiberis Recens, 10 grams of Herba Cirrohopetali Andersoniis, 15 grams of Cacumen Securinegae Suffruticosaes, 15 grams of careless imperial roots, 9 grams of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 9 grams of Herba Cryptocoryne yunnanensis, 20 grams, white hog snout hole, 15 grams of Herba Ophioglossis, 20 grams of triangle leaf Rhizoma Belamcandaes, 10 grams of Saussurea arenaria Maxim., 15 grams of meat root Radix Crepidis elongatae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of intestinal Behcet disease.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: 10 grams of Radix seu folium cipakessae cinerascentiss, 15 grams of precipice Rhizoma Zingiberis Recens, 10 grams of Herba Cirrohopetali Andersoniis, 15 grams of Cacumen Securinegae Suffruticosaes, 15 grams of careless imperial roots, 9 grams of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 9 grams of Herba Cryptocoryne yunnanensis, 20 grams, white hog snout hole, 15 grams of Herba Ophioglossis, 20 grams of triangle leaf Rhizoma Belamcandaes, 10 grams of Saussurea arenaria Maxim., 15 grams of meat root Radix Crepidis elongatae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of intestinal Behcet disease.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: 10 grams of Radix seu folium cipakessae cinerascentiss, 15 grams of precipice Rhizoma Zingiberis Recens, 10 grams of Herba Cirrohopetali Andersoniis, 15 grams of Cacumen Securinegae Suffruticosaes, 15 grams of careless imperial roots, 9 grams of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 9 grams of Herba Cryptocoryne yunnanensis, 20 grams, white hog snout hole, 15 grams of Herba Ophioglossis, 20 grams of triangle leaf Rhizoma Belamcandaes, 10 grams of Saussurea arenaria Maxim., 15 grams of meat root Radix Crepidis elongatae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of intestinal Behcet disease.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. a Chinese medicine for the treatment of intestinal Behcet disease, it is characterized in that, by the medical material of following weight proportion, be prepared from: 10 parts of Radix seu folium cipakessae cinerascentiss, 15 parts of precipice Rhizoma Zingiberis Recens, 10 parts of Herba Cirrohopetali Andersoniis, 15 parts of Cacumen Securinegae Suffruticosaes, 15 parts of careless imperial roots, 9 parts of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 9 parts of Herba Cryptocoryne yunnanensis, 20 parts, white hog snout hole, 15 parts of Herba Ophioglossis, 20 parts of triangle leaf Rhizoma Belamcandaes, 10 parts of Saussurea arenaria Maxim., 15 parts of meat root Radix Crepidis elongatae.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3103465A1 (en) * | 2015-06-10 | 2016-12-14 | Raman Mehta | Formulations for the treatment of mucosal lesions |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895514A (en) * | 2006-06-23 | 2007-01-17 | 陈文渊 | Medicine for treating behcet's syndrome |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895514A (en) * | 2006-06-23 | 2007-01-17 | 陈文渊 | Medicine for treating behcet's syndrome |
Non-Patent Citations (1)
| Title |
|---|
| 陈文台，彭孝纬: "肠白塞病的临床特点", 《国际消化病杂志》, vol. 31, no. 2, 30 April 2011 (2011-04-30), pages 75 - 78 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3103465A1 (en) * | 2015-06-10 | 2016-12-14 | Raman Mehta | Formulations for the treatment of mucosal lesions |
| WO2016198942A1 (en) | 2015-06-10 | 2016-12-15 | Raman Mehta | Formulations for the treatment of mucosal lesions |
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| CN103690709B (en) | 2016-03-09 |
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