CN1889944A - ErbB2激酶过量表达相关疾病的治疗 - Google Patents

ErbB2激酶过量表达相关疾病的治疗 Download PDF

Info

Publication number
CN1889944A
CN1889944A CNA2004800362204A CN200480036220A CN1889944A CN 1889944 A CN1889944 A CN 1889944A CN A2004800362204 A CNA2004800362204 A CN A2004800362204A CN 200480036220 A CN200480036220 A CN 200480036220A CN 1889944 A CN1889944 A CN 1889944A
Authority
CN
China
Prior art keywords
cancer
cocoa
erbb2
oligomers
polyphenols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800362204A
Other languages
English (en)
Chinese (zh)
Inventor
H·H·施米茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mars Inc
Original Assignee
Mars Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mars Inc filed Critical Mars Inc
Publication of CN1889944A publication Critical patent/CN1889944A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2004800362204A 2003-10-10 2004-10-08 ErbB2激酶过量表达相关疾病的治疗 Pending CN1889944A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51060403P 2003-10-10 2003-10-10
US60/510,604 2003-10-10

Publications (1)

Publication Number Publication Date
CN1889944A true CN1889944A (zh) 2007-01-03

Family

ID=34435110

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800362204A Pending CN1889944A (zh) 2003-10-10 2004-10-08 ErbB2激酶过量表达相关疾病的治疗

Country Status (9)

Country Link
US (1) US20050245601A1 (enExample)
EP (1) EP1670455A4 (enExample)
JP (1) JP2007508316A (enExample)
CN (1) CN1889944A (enExample)
AU (1) AU2004280257A1 (enExample)
CA (1) CA2541548A1 (enExample)
IL (1) IL174763A0 (enExample)
RU (1) RU2006115615A (enExample)
WO (1) WO2005034879A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101918844A (zh) * 2007-06-18 2010-12-15 米迪缪尼有限公司 表达epha2和erbb2的细胞的协同治疗

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1896008A4 (en) * 2005-06-29 2010-04-07 Mars Inc COMPOSITIONS AND METHODS FOR INDUCING VASODILATION OF PERIPHERAL BLOOD VESSELS
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
JP2009521475A (ja) * 2005-12-23 2009-06-04 マース インコーポレーテッド 皮膚の保護および改善
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
CA2662491A1 (en) * 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554645A (en) * 1994-10-03 1996-09-10 Mars, Incorporated Antineoplastic cocoa extracts and methods for making and using the same
US6297273B1 (en) * 1996-04-02 2001-10-02 Mars, Inc. Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions
EP1015006A4 (en) * 1996-04-02 2003-09-24 Mars Inc COCOA EXTRACT COMPOUNDS AND METHOD FOR THEIR PRODUCTION AND USE
US6207842B1 (en) * 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
US6156912A (en) * 1999-04-09 2000-12-05 Mars, Incorporated 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation
US7015338B1 (en) * 1999-04-15 2006-03-21 Mars Incorporated Synthetic methods for preparing procyanidin oligomers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101918844A (zh) * 2007-06-18 2010-12-15 米迪缪尼有限公司 表达epha2和erbb2的细胞的协同治疗

Also Published As

Publication number Publication date
WO2005034879A2 (en) 2005-04-21
JP2007508316A (ja) 2007-04-05
WO2005034879A3 (en) 2005-12-29
EP1670455A2 (en) 2006-06-21
AU2004280257A1 (en) 2005-04-21
RU2006115615A (ru) 2007-11-27
IL174763A0 (en) 2008-04-13
EP1670455A4 (en) 2008-10-15
US20050245601A1 (en) 2005-11-03
CA2541548A1 (en) 2005-04-21

Similar Documents

Publication Publication Date Title
CN1889944A (zh) ErbB2激酶过量表达相关疾病的治疗
US9416196B2 (en) Composition for prophylaxis or treatment of vascular or cardiac valvular calcification comprising dipeptidyl peptidase-4 inhibitor
CN101516407B (zh) 改善精氨酸酶水平/活性
Meeprom et al. Grape seed extract supplementation prevents high-fructose diet-induced insulin resistance in rats by improving insulin and adiponectin signalling pathways
US7371776B2 (en) Methods and compositions for treating cancer
EP3263134A1 (en) Composition for preventing or treating valve calcification, containing dpp-4 inhibitor
KR20080065593A (ko) 지방세포의 지방 축적을 관리하는 방법
EP3318254A1 (en) Azelaic acid composition having adipose tissue triglyceride degradation effect
Wang et al. Curcumin analog JM-2 alleviates diabetic cardiomyopathy inflammation and remodeling by inhibiting the NF-κB pathway
KR20200056367A (ko) 유파틸린을 유효성분으로 포함하는 비만 예방, 치료, 또는 개선용 조성물
JP2013173719A (ja) スダチチンを有効成分とする、メタボリックシンドロームの予防及び/又は治療剤
CN109640978B (zh) 以芹菜素、姜黄素及和厚朴酚为有效成分包含的肺癌预防或治疗用药学组合物
KR20160149049A (ko) 흑미 호분층의 추출물을 유효성분으로 함유하는 골다공증 예방 및 치료용 약학적 조성물
KR101637517B1 (ko) 비타민 u를 유효성분으로 함유하는 비만 예방 또는 치료용 조성물
CN107148277B (zh) 一种抑制脂肪细胞分化和胰岛素耐受的药物
KR101232872B1 (ko) 스핑고신-1-포스페이트(sphingosine-1-phosphate) 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 비만 예방 및 치료용 약학적 조성물
TW201424743A (zh) Igf-1產生促進劑
KR20220071741A (ko) 대두 추출물 및 효소적으로 처리된 루틴, 이의 염, 이의 입체 이성질체, 이의 수화물 또는 이의 용매화물을 유효성분으로 함유하며 미토콘드리아의 활성을 촉진시키며 백색 지방세포로부터 갈색 지방세포로의 형성을 유도하는 항비만 조성물
Nguyen Effects of nacre supplementation on bone loss (induced or natural) in rodent models
EP4461294A1 (en) Lipolytic and antiadipogenic coumarin derivatives
US20220313620A1 (en) Composition for preventing and treating tauopathies
CN113712950A (zh) 创伤酸在制备抗肥胖药物或抗肥胖保健品中的应用
KR20220142284A (ko) 네오헤스페리딘 디하이드로칼콘 당전이체를 포함하는 비만 예방, 개선 또는 치료용 조성물
TW201906820A (zh) 致癌抑制劑
WO2007053639A2 (en) A-type procyanidins and cox-2 expression

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication