CN1876062A - Preparation method of traditional Chinese medicine for treating hepatitis B and liver cirrhosis and Chinese medicine prepared thereby - Google Patents
Preparation method of traditional Chinese medicine for treating hepatitis B and liver cirrhosis and Chinese medicine prepared thereby Download PDFInfo
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Abstract
The invention relates to a process for preparing Chinese medicament for the treatment of hepatitis B and cirrhosis, wherein the medicament is prepared from the raw material herbs of toad, Eupolyphaga Sinensis Walker, leeches, ganoderma lucidum, root of herbaceous peony, tortoise shell, notoginseng, turtle shell, ants, giant knotweed rhizome, dandelion, white atractylodes rhizome, cantharis, root of red rooted saliva, black nightshade, schisandra fruit, Canton love-pea vine, subprostrate sophora root, Paris polyphylla, astragalus root and Chinese caterpillar fungus.
Description
Technical field
The present invention relates to a kind of preparation method of Chinese medicine, relate in particular to a kind of preparation method of Chinese medicine of controlling hepatitis B, liver cirrhosis, also relate to Chinese medicine with this method preparation.
Background technology
Hepatitis B be a kind of popular extensively, sickness rate is high, hazardness is big, the route of transmission is wide, the infectious disease of routine treatment weak curative effect, the morbidity of it and liver cirrhosis, hepatocarcinoma has confidential relation.According to authority, 90% Patients with Primary is all carried hepatitis B virus, and particularly chronic active hepatitis major part (about 40-50%) can change liver cirrhosis or hepatocarcinoma into, and it is very big to human life's health hazard.Hepatitis B is that three disasters that medical circle is generally acknowledged one of are cured the desease.The therapy commonly used of treatment hepatitis virus has therapies such as Chinese traditional treatment, western medical treatment, therapy of combining Chinese and Western medicine at present; general weak curative effect; its reason has four: one, because hepatitis virus virus is present in hepatocyte endoreduplication breeding, and liver cell nuclear has the peplos of one deck protectiveness to encase outward.This peplos mainly is that protein and membrane lipid are formed, be a kind of butyrous peplos, and liver treating medicine at present commonly used as Chinese herbal medicine, Chinese patent medicine, Western medicine etc. all be water soluble drug, because water oil is immiscible, so they all can't penetrate liver plasma membrane and enter liver cell nuclear, more can not penetrate the peplos of hepatitis B virus, therefore the hepatitis virus in the liver cell nuclear can't be killed, removed; Its two, routine treatment treatment hepatitis B all is that the single hepatoprotective medicine of utilization is main, and clinical showing will be cured hepatitis antiviral simultaneously, improves immune function of human body and liver function protecting anti-hepatic fibrosis; They are three years old, routine treatment treatment hepatitis virus all is " thousand people, one medicine; Wan Renyi side ", can not the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs symptomatic treatment, though hepatitis virus mainly is a liver injury, but it can relate to the vital organs of the human body of human body, make human righteousness's deficiency, immunologic hypofunction make the hepatitis virus chronicity, and traditional tcm therapy thinks that all hepatitis virus is to be caused by damp and hot evil poison, all be to serve as main the treatment on the method for treatment with heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis or blood circulation promoting and blood stasis dispelling, soothing liver-QI for relieving depression, the result is damp and hot to remove, but hepatitis virus can not thoroughly be removed easy chronicity; Its four, have different shaped and hypotype in the hepatitis virus, chronic hepatitis is easy to take place virus variation, the immune system difficulty of human body is distinguished the dissident, not easy-clear.
Liver cirrhosis is a kind of common disease, is one of main death reason of crowd, causes that the reason of liver cirrhosis is a lot, because liver cirrhosis is to cause the most common most important reason of hepatic space occupying lesion behind the hepatitis B.Develop into liver cirrhosis from hepatitis B, medically generally liver cirrhosis is being divided into compensatory cirrhosis and decompensated liver cirrhosis according to the damaged condition of liver function.The compensatory phase is called the concealment phase again.The patient symptom of decompensated liver cirrhosis is heavier, and malaise is arranged, and becomes thin, and complexion is gloomy, detests oil, diarrhoea, gingival hemorrhage, anemia and gynaecomastia, female irregular menstruation, sterility and infertility.Patient can have the spleen enlargement, ascites and esophagus fundus ventricularis varication, two lower limbs edema, hydrosarca can appear in serious patient, particularly esophagus fundus ventricularis varication, can cause massive hemorrhage when breaking, rescue and untimelyly will cause death, the patient of ascites is if bacterial infection, cause peritonitis, the patient that fails to respond to any medical treatment also can be dead.
Liver cirrhosis is in case form that to rethink reverse often very difficult, modern medicine all liver cirrhosis irreversible pathological changes.Doctor trained in Western medicine at most can only hepatoprotective, but clinical effectiveness is undesirable or side effect is bigger, and the research of treatment by Chinese herbs liver cirrhosis has in recent years obtained bigger progress.Treatment to active liver cirrhosis, by the Therapeutic Method of chronic active hepatitis and actively prevent hepatic fibrosis, the traditional Chinese medical science has the classification of liver cirrhosis: the liver stagnant heat is accumulate type, insufficiency of the spleen qi-deficiency type, blood stasis network resistance type, liver-kidney yin deficiency, air water fight stagnant type, deficiency of YIN dropsy type.Its rule of treatment be transfer and to be " the harmonizing the liver and spleen kidney, movable blood soft hard, clearing away heat-damp and promoting diuresis, benefiting qi and nourishing blood, intestinal stasis relieving helps three warmers, gasification, row water collateral dredging." can use strong liver softening the hard mass, and blood circulation promoting and blood stasis dispelling is the core of treatment.
The treatment of static property liver cirrhosis, except that the hepatoprotective therapy, should be based on the anti-hepatic fibrosis treatment, activating blood and removing stasis Method energy microcirculation improvement also improves knot and forms, and Fibrotic liver is reversed come, and returns to normal.
Ascites is the most outstanding performance of liver cirrhosis, when reaching 500ML Shi doctor, ascites volume just can check out, in a single day ascites appear in patient with liver cirrhosis, illustrate that hepatocellular damage is heavier, want active treatment, by treatment, most ascites still can be eliminated, also there is the ascites of a few patients (accounting for 1/6) to become refractory ascites, needs the specific process treatment.
Summary of the invention
The purpose of this invention is to provide a kind of preparation method of Chinese medicine of hepatitis B, liver cirrhosis and Chinese medicine for preparing with this method controlled.The crude drug of the Chinese medicine that the preparation method of Chinese medicine that adopts the present invention to control hepatitis B, liver cirrhosis prepares is based on animal drugs; be aided with other Chinese herbal medicine; can antiviral; can improve immune function of human body again; liver function protecting anti-hepatic fibrosis is simultaneously effectively treated hepatitis B, liver cirrhosis and has been overcome the deficiency that present treatment hepatitis B, liver cirrhosis exist.
The present invention controls the preparation method of Chinese medicine of hepatitis B, liver cirrhosis, and its step is as follows:
1. crude drug and weight proportion thereof are:
Radix Paeoniae Alba 10-15g, Carapax et Plastrum Testudinis 10-30g, Radix Notoginseng 6-15g, Carapax Trionycis 10-30g,
Bufo siccus 5-10g, ground beetle 10-15g, Hirudo 2-7g, Ganoderma 10-20g,
Formica fusca 5-10g, Rhizoma Polygoni Cuspidati 10-15g, Herba Taraxaci 10-30g, Rhizoma Atractylodis Macrocephalae 10-20g,
Mylabris 0.03-5g, Radix Salviae Miltiorrhizae 10-20g, Herba Solani Nigri 10-15g, Fructus Schisandrae Chinensis 10-17g,
Herba Abri 10-20g, Radix Sophorae Tonkinensis 3-8g, seven leaves-branch flower 10-15g, Radix Astragali 10-35g,
Cordyceps 5-15g;
Crude drug and preferred weight proportioning thereof are:
Radix Paeoniae Alba 13-15g, Carapax et Plastrum Testudinis 15-30g, Radix Notoginseng 10-15g, Carapax Trionycis 20-30g,
Bufo siccus 7-10g, ground beetle 12-15g, Hirudo 2-5g, Ganoderma 15-20g,
Formica fusca 5-8g, Rhizoma Polygoni Cuspidati 12-15g, Herba Taraxaci 10-20g, Rhizoma Atractylodis Macrocephalae 10-17g,
Mylabris 0.03-1g, Radix Salviae Miltiorrhizae 15-20g, Herba Solani Nigri 10-13g, Fructus Schisandrae Chinensis 10-15g,
Herba Abri 15-20g, Radix Sophorae Tonkinensis 5-8g, Rhizoma Paridis 12-15g, Radix Astragali 15-35g,
Cordyceps 8-15g;
With the animal class crude drug-Bufo siccus in the required above-mentioned raw materials medicine, ground beetle, Mylabris, Hirudo, Carapax et Plastrum Testudinis, Carapax Trionycis, Formica fusca, and plant class crude drug-Ganoderma, the Radix Paeoniae Alba, Radix Notoginseng, Rhizoma Polygoni Cuspidati, Herba Taraxaci, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Herba Solani Nigri, Fructus Schisandrae Chinensis, Herba Abri, Radix Sophorae Tonkinensis, Rhizoma Paridis, the Radix Astragali, Cordyceps pulverize with pulverizer respectively;
3. the above-mentioned animal class crude drug of having pulverized was decocted 30 minutes, put into high-pressure bottle again;
4. the above-mentioned class of comminuted plants crude drug is put into above-mentioned high-pressure bottle, is heated to 120 ℃, decocted again 15 minutes, filter, obtain decoction---control the Chinese medicine of hepatitis B, liver cirrhosis.
The present invention controls the instructions of taking of the Chinese medicine of hepatitis B, liver cirrhosis: one pair of every day, one day twice; 20-30 day is a course of treatment.
Control the Chinese medicine of the preparation method of Chinese medicine preparation of hepatitis B, liver cirrhosis by the present invention, also can make common dosage form, as electuary, tablet, oral liquid, honeyed pill, the watered pill, capsule etc. by the pharmaceutics common method.
That the present invention screening has is soothing the liver, easing the affected liver, soft liver, tonifying liver, hepatoprotective, protect the liver, nourishing the liver, tonifying liver, liver heat removing function of gallbladder promoting, detoxifcation, toxin expelling, detoxicating and suppress the stronger Chinese medicine of virus replication power, be principal agent with the animal drugs wherein, be aided with that other Chinese herbal medicine is fried to form.It utilizes animal drugs all to have the lubricant component of animal cleverly; promptly has stronger antiviral effect; has interlinking with hepatocyte again; therefore can penetrate hepatocyte fully, up hill and dale enters liver cell nuclear; directly the hepatitis B virus in the liver cell nuclear in the blood, hepatitis C are killed and remove and get rid of externally, collaborative other medicines improve the immunity of human body, the liver protecting; prevent hepatic fibrosis, cure hepatitis B, hepatitis C at short notice.
Radix Paeoniae Alba nature and flavor hardship, acid in the crude drug of the present invention, be slightly cold, have protecting the liver and strengthen the body immunity function;
The Carapax et Plastrum Testudinis nature and flavor are sweet, salty, cold, nourishing YIN and benefiting blood, and the kidney tonifying YANG hyperactivity suppressing, bone strengthening, sweet salty and cold, kind nourishing YIN branch can YIN nourishing and heart-fire falls in YANG hyperactivity suppressing, and clearind deficient heat nourishes blood, and can only collapse by controlling nocturnal emission with astringent drugs, and reinforcing the heart is arranged, and the kidney invigorating is enriched blood.Excessive the moon nourishes blood, and improves immunity function;
Sweet, the little hardship of Radix Notoginseng nature and flavor, tepor, have dissipating blood stasis hemostasis, subduing swelling and relieving pain function, prove that after deliberation Radix Notoginseng can improve the phagocytic rate and the phagocytic index of macrophage, activate humoral immune reaction, improve immunologic function, Radix Notoginseng injection can reduce hepatic injury and serum transaminase, the liver protecting, and the jaundice of elimination is arranged and increase the bile flow effect;
The Carapax Trionycis nature and flavor are salty, be slightly cold, and can suppress connective tissue proliferation, strengthen plasma protein and prolong the antibody life period, suppress the growth of hepatoma carcinoma cell;
Bufo siccus nature and flavor suffering, cold, poisonous have detoxicating and resolving stagnation of pathogens, antiinflammatory, diuresis and analgesia function;
The ground beetle nature and flavor are salty, cold, slightly poisonous, have the promotion fibrinolysis, hepatoprotective, blood fat reducing, cholesterol and blood viscosity effect;
The Hirudo nature and flavor are salty, bitter, flat to have anticoagulation, blood viscosity lowering, and blood vessel is expanded in blood fat reducing, promotes absorption of hematoma and immunosuppressive action;
The Ganoderma nature and flavor are sweet, flat, have coronary artery dilating, improve coronary circulation, strengthen the phagocytic activity of reticuloendothelial cell and suppressed function such as sensitive media release;
Formica fusca has the function of the harmful substance in vigorate qi and replenish the blood, nourishing the kidney and liver, anti-inflammation, the eliminating medicine;
Rhizoma Polygoni Cuspidati nature and flavor hardship, salty has that the liver heat removing gallbladder is damp and hot, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, rushes down function down, can strengthen bile secretion, suppresses the hepatitis B antigen positive, suppresses the accumulation of lipid peroxidation at liver, alleviates hepatic injury, the liver protecting;
Herba Taraxaci nature and flavor hardship, sweet, cold has antiviral, antibiotic, function of gallbladder promoting, diuresis, protects the liver and improve the body immunity function;
Rhizoma Atractylodis Macrocephalae nature and flavor hardship, salty, warm, have be good for the stomach, protect the liver, strong, blood vessel dilating and anticoagulation function;
Mylabris nature and flavor suffering, cold, very toxic has antiinflammatory, antifungic action, can resist hepatic injury due to the carbon tetrachloride and the rising of GP7, also has immunosuppressive action;
Radix Salviae Miltiorrhizae nature and flavor hardship, be slightly cold, have blood circulation promoting and enriching, the liver-protecting function that nourishes blood can suppress or alleviate hepatocellular degeneration necrosis and inflammatory reaction, helps the reparation of hepatic injury, and suppresses fibroplasia in the liver;
Herba Solani Nigri nature and flavor hardship, cold, slightly poisonous has heat-clearing and toxic substances removing, promoting blood circulation and detumescence, inducing diuresis for treating stranguria syndrome function;
The acid of Fructus Schisandrae Chinensis nature and flavor, sweet, temperature have vasodilator, the heart tonifying hepatoprotective, promote metabolism and antiviral, antibiotic, strengthen the reticuloendothelial system cytophagy;
The Herba Abri nature and flavor are sweet, light, cold has clearing away heat-damp and promoting diuresis, the Shugan Zhitong function;
Radix Sophorae Tonkinensis nature and flavor hardship, cold, has effects for removing toxic heat, prove after deliberation, hepatic injury animal serum glutamate pyruvate transaminase there is the reduction effect, hepatocellular degeneration, necrosis, the hepatitis cell of chronic hepatitis soaked contain and stasis of blood gallbladder has the improvement effect, can alleviate hepatic injury and the very fast slough of repairing, liver glycogen content is increased, and hepatitis B virus had direct repression, also can improve the human body function of exempting from service;
Rhizoma Paridis property of medicine bitter in the mouth, be slightly cold, slightly poisonous, have heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the arresting convulsion function relieves dizziness, high fever, infantile convulsions, epilepsy, etc.;
Radix Astragali nature and flavor are sweet, tepor, have the liver protecting, prevent the effect that liver glycogen reduces, and Radix Astragali decoction can make total protein concentration increase, and reduces hepatic injury;
Cordyceps: nature and flavor, Gan Wen, but but not only kidney tonifying YANG invigorating but also tonification lung yin, hemostasis and phlegm.The treatment impotence and seminal emission, soreness of waist and knee joint, chronic cough dyspnea due to deficiency, chronic cough expectorant blood, and body void or spontaneous perspiration fear of cold or the like after being ill.
Crude drug of the present invention is selected the principal agent of animal drugs as treatment hepatitis B, liver cirrhosis for use, these medicine great majority all have stronger toxicity, has stronger antiviral effect, and all have the oils and fats composition of animal, because liver plasma membrane is a kind of butyrous peplos, both have interlinking, therefore it not only can effectively kill, remove the hepatitis B virus in the blood, and it can enter liver cell nuclear by the slap-up liver plasma membrane that penetrates, directly the hepatitis B virus in the liver cell nuclear is killed and excretes, can reach the purpose of curing hepatitis B in a short time.Liver cirrhosis is a kind of common disease, is one of main death reason of crowd, causes that the reason of liver cirrhosis is a lot, because liver cirrhosis is to cause the most common most important reason of hepatic space occupying lesion behind the hepatitis B.Develop into liver cirrhosis from hepatitis B, medically generally liver cirrhosis is being divided into compensatory cirrhosis and decompensated liver cirrhosis according to the damaged condition of liver function.The compensatory phase is called the concealment phase again.The patient symptom of decompensated liver cirrhosis is heavier, and malaise is arranged, and becomes thin, and complexion is gloomy, detests oil, diarrhoea, gingival hemorrhage, anemia and gynaecomastia, female irregular menstruation, sterility and infertility.Patient can have the spleen enlargement, ascites and esophagus fundus ventricularis varication, two lower limbs edema, hydrosarca can appear in serious patient, particularly esophagus fundus ventricularis varication, can cause massive hemorrhage when breaking, rescue and untimelyly will cause death, the patient of ascites is if bacterial infection, cause peritonitis, the patient that fails to respond to any medical treatment also can be dead.
Liver cirrhosis is in case form that to rethink reverse often very difficult, modern medicine all liver cirrhosis irreversible pathological changes.Doctor trained in Western medicine at most can only hepatoprotective, but clinical effectiveness is undesirable or side effect is bigger, and the research of treatment by Chinese herbs liver cirrhosis has in recent years obtained bigger progress.Treatment to active liver cirrhosis, by the Therapeutic Method of chronic active hepatitis and actively prevent hepatic fibrosis, the traditional Chinese medical science has the classification of liver cirrhosis: the liver stagnant heat is accumulate type, insufficiency of the spleen qi-deficiency type, blood stasis network resistance type, liver-kidney yin deficiency, air water fight stagnant type, deficiency of YIN dropsy type.Its rule of treatment be transfer and to be " the harmonizing the liver and spleen kidney, movable blood soft hard, clearing away heat-damp and promoting diuresis, benefiting qi and nourishing blood, intestinal stasis relieving helps three warmers, gasification, row water collateral dredging." can use strong liver softening the hard mass, and blood circulation promoting and blood stasis dispelling is the core of treatment.
The treatment of static property liver cirrhosis, except that the hepatoprotective therapy, should be based on the anti-hepatic fibrosis treatment, activating blood and removing stasis Method energy microcirculation improvement also improves knot and forms, and Fibrotic liver is reversed come, and returns to normal.
Ascites is the most outstanding performance of liver cirrhosis, when reaching 500ML Shi doctor, ascites volume just can check out, in a single day ascites appear in patient with liver cirrhosis, illustrate that hepatocellular damage is heavier, want active treatment, by treatment, most ascites still can be eliminated, also there is the ascites of a few patients (accounting for 1/6) to become refractory ascites, needs the specific process treatment.
The present invention adopts the three therapeutic methods of traditional Chinese medicine such as antibiotic therapy, immune function of human body therapy, liver function protecting anti-hepatic fibrosis therapy and one therapy for treating hepatitis B, liver cirrhosis; the medicine of existing detoxifcation, toxin expelling, detoxicating in the prescription; the medicine that strengthens immune function of human body and the liver protecting anti-hepatic fibrosis is arranged again; so curative effect height; cure rate is 86%, and total effective rate reaches 98%.The present invention has curative effect preferably to hepatosplenomegaly, hepatic ascites, hepatitis C etc.
Raw material required for the present invention, equipment all have commercially available.
The specific embodiment
Embodiment 1
Control the Chinese medicine of hepatitis B, liver cirrhosis disease by above-mentioned preparation method preparation, the first step wherein, the component of crude drug and weight proportion thereof are: Bufo siccus 5g, ground beetle 10g, Hirudo 2g, Ganoderma 10g, Radix Paeoniae Alba 10g, Carapax et Plastrum Testudinis 10g, Radix Notoginseng 6g, Carapax Trionycis 10g, Formica fusca 5g, Rhizoma Polygoni Cuspidati 10g, Herba Taraxaci 10g, Rhizoma Atractylodis Macrocephalae 10g, Mylabris 0.03g, Radix Salviae Miltiorrhizae 10g, Herba Solani Nigri 10g, Fructus Schisandrae Chinensis 10g, Herba Abri 10g, Radix Sophorae Tonkinensis 3g, Rhizoma Paridis 10g, Radix Astragali 10g, Cordyceps 5g.
Embodiment 2
Control the Chinese medicine of hepatitis B, liver cirrhosis by above-mentioned preparation method preparation, the first step wherein, the component of crude drug and weight proportion thereof are: Bufo siccus 10g, ground beetle 15g, Hirudo 7g, Ganoderma 20g, Radix Paeoniae Alba 15g, Carapax et Plastrum Testudinis 30g, Radix Notoginseng 15g, Carapax Trionycis 30g, Formica fusca 10g, Rhizoma Polygoni Cuspidati 15g, Herba Taraxaci 30g, Rhizoma Atractylodis Macrocephalae 20g, Mylabris 5g, Radix Salviae Miltiorrhizae 20g, Herba Solani Nigri 15g, Fructus Schisandrae Chinensis 17g, Herba Abri 20g, Radix Sophorae Tonkinensis 8g, Rhizoma Paridis 15g, Radix Astragali 35g, Cordyceps 15g.；
Embodiment 3
Control the Chinese medicine of hepatitis B, liver cirrhosis disease by above-mentioned preparation method preparation, the first step wherein, the component of crude drug and weight proportion thereof are: Bufo siccus 7g, ground beetle 12g, Hirudo 5g, Ganoderma 15g, Radix Paeoniae Alba 13g, Carapax et Plastrum Testudinis 15g, Radix Notoginseng 10g, Carapax Trionycis 20g, Formica fusca 8g, Rhizoma Polygoni Cuspidati 12g, Herba Taraxaci 20g, Rhizoma Atractylodis Macrocephalae 17g, Mylabris 1g, Radix Salviae Miltiorrhizae 15g, Herba Solani Nigri 13g, Fructus Schisandrae Chinensis 15g, Herba Abri 15g, Radix Sophorae Tonkinensis 5g, Rhizoma Paridis 12g, Radix Astragali 15g, Cordyceps 8g.；
Clinical observation is summed up
One. the diagnostic criteria of hepatitis B, liver cirrhosis:
1. type hepatitis human body often occurs: the hepatic region expands, and yellow urine is weak, uncomfortable in chest, poor appetite, insomnia and dreamful sleep.
2. the sclerosis human body often occurs: liver pain, and weak, to become thin, complexion is gloomy, detests oil, diarrhoea, gingival hemorrhage, anemia etc.
Two. control the instructions of taking of the Chinese medicine of hepatitis B, liver cirrhosis: one pair of every day, one day twice; 20-30 day is a course of treatment.
Three. efficacy assessment standard: cure:
1. the hepatitis B human body often occurs: the hepatic region expands, and yellow urine is weak, uncomfortable in chest, poor appetite, clinical symptom disappearance such as insomnia and dreamful sleep.
2. the liver cirrhosis human body often occurs: liver pain, and weak, to become thin, complexion is gloomy, detests oil, diarrhoea, gingival hemorrhage, clinical symptom disappearance such as anemia.
1. effective:
1) the hepatitis human body often occurs: the hepatic region expands, and yellow urine is weak, uncomfortable in chest, poor appetite, and clinical symptom reliefs such as insomnia and dreamful sleep are clearly better.
2) the liver cirrhosis human body often occurs: liver pain, and weak, to become thin, complexion is gloomy, detests oil, diarrhoea, gingival hemorrhage, clinical symptom reliefs such as anemia are clearly better.
Four. therapeutic effect: clinical observation is totally 100 examples, wherein male 64 examples, women 36 examples; Cure 86 examples, reach 86%; Effective 12 examples reach 12%; Total effective rate reaches 98%.
Model case
1. Jinsui River, the man, 48 years old, hepatitis "great three positive" 9 years, the HBV-DNA hepatitis B virus quantitatively is 2.99 * 10
8C0PES/Ml.Glutamate pyruvate transaminase 348u/L, glutamic oxaloacetic transaminase, GOT 436u/L the hepatic region occurs and expands, dizziness, weak, yellow urine, uncomfortable in chest, poor appetite, insomnia, use the interferon two-and-a-half years, take the He Jin fourth more than 3 years, seeking medical advice does not everywhere all have effect, took the Chinese medicine that the present invention controls the hepatitis B viral disease afterwards, after the course of treatment (20 days), forwarded young waiter in a wineshop or an inn's sun to by great three positive, hepatitis b virus hbv-DNA viruses quantitatively reduces to 1.30 * 10
4COPES/Ml, glutamate pyruvate transaminase 0-40u/L, glutamic oxaloacetic transaminase, GOT 0-40u/L the hepatic region occurs and expands, dizziness, weak, yellow urine, uncomfortable in chest, poor appetite, transference cures such as insomnia, continue to take one the course of treatment hepatitis "great three positive" turn out cloudy hepatitis b virus hbv-DNA1.00 * 10 entirely
3COPES/Ml, feminine gender, all symptoms all disappear, the physical recovery normal health.
2. sharp, the man, 32 years old, hepatitis "great three positive" 6 years, hepatalgia appears in liver cirrhosis, with hepatic ascites, abdominal distention, liver cirrhosis, uncomfortable in chest, weak, detest oil, become thin, the complexion dark, poor appetite is seen the doctor for treatment everywhere, has used a lot of medicines, controls more serious and more serious, draws water and ascites, does not have effect.The doctor said this cirrhotic ascites at that time, controlled bad.Took the Chinese medicine that the present invention controls hepatitis B, cirrhotic ascites afterwards, ascites had disappeared down in three to seven days, after the course of treatment (30 days), hepatalgia, abdominal distention, ascites, uncomfortable in chest, weak, detest oil, the complexion dark, poor appetite takes a turn for the better many, continues to take two courses of treatment again, and the hepatitis B small three positive has been turned out cloudy, it is normal that liver cirrhosis recovers, and health is also very normal.
3. prolong the autumn, the woman 33 years old, got hepatitis C 5 years, the quantitative HCV-RNA1.529 of hepatitis C virus * 10
6COPY/Ml, it is vexed bloated, weak the hepatic region to occur, insomnia, dreaminess is sought medical advice and medicine everywhere, has used a lot of medicines, all the time do not have effect, take the Chinese medicine that the present invention controls hepatitis B, hepatitis C disease afterwards, all turn out cloudy a course of treatment (30 days), the quantitative HCV-RNA virus of hepatitis C virus is feminine gender＜80COPES/ml quantitatively, and glutamate pyruvate transaminase is normal, 0-40u/L, the normal 0-40u/L of glutamic oxaloacetic transaminase, GOT, the hepatic region is vexed to expand, weak, insomnia, dreaminess disappears, and health is all healthy normal.
Claims (5)
1. preparation method of Chinese medicine of controlling hepatitis B, liver cirrhosis, its step is as follows:
1) crude drug and weight proportion thereof are:
Radix Paeoniae Alba 10-15g, Carapax et Plastrum Testudinis 10-30g, Radix Notoginseng 6-15g, Carapax Trionycis 10-30g,
Bufo siccus 5-10g, ground beetle 10-15g, Hirudo 2-7g, Ganoderma 10-20g,
Formica fusca 5-10g, Rhizoma Polygoni Cuspidati 10-15g, Herba Taraxaci 10-30g, Rhizoma Atractylodis Macrocephalae 10-20g,
Mylabris 0.03-5g, Radix Salviae Miltiorrhizae 10-20g, Herba Solani Nigri 10-15g, Fructus Schisandrae Chinensis 10-17g,
Herba Abri 10-20g, Radix Sophorae Tonkinensis 3-8g, Rhizoma Paridis 10-15g, Radix Astragali 10-35g,
Cordyceps 5-15g;
2) with the animal class crude drug-Bufo siccus in the required above-mentioned raw materials medicine, ground beetle, Hirudo, Carapax et Plastrum Testudinis, Carapax Trionycis, Formica fusca, and plant class crude drug-Ganoderma, the Radix Paeoniae Alba, Radix Notoginseng, Rhizoma Polygoni Cuspidati, Herba Taraxaci, the Rhizoma Atractylodis Macrocephalae, Mylabris, Radix Salviae Miltiorrhizae, Herba Solani Nigri, Fructus Schisandrae Chinensis, Herba Abri, Radix Sophorae Tonkinensis, Rhizoma Paridis, the Radix Astragali, Cordyceps pulverize with pulverizer respectively;
3) the above-mentioned animal class crude drug of having pulverized was decocted 30 minutes, put into high-pressure bottle again;
4) the above-mentioned class of comminuted plants crude drug is put into above-mentioned high-pressure bottle, is heated to 120 ℃, fried in shallow oil again 15 minutes, filter, obtain decoction---control the Chinese medicine of hepatitis B, liver cirrhosis.
2. control the preparation method of Chinese medicine of hepatitis B, liver cirrhosis according to claim 1, it is characterized in that, crude drug and weight proportion thereof are:
Radix Paeoniae Alba 13-15g, Carapax et Plastrum Testudinis 15-30g, Radix Notoginseng 10-15g, Carapax Trionycis 20-30g,
Bufo siccus 7-10g, ground beetle 12-15g, Hirudo 2-5g, Ganoderma 15-20g,
Formica fusca 5-8g, Rhizoma Polygoni Cuspidati 12-15g, Herba Taraxaci 10-20g, Rhizoma Atractylodis Macrocephalae 10-17g,
Mylabris 0.03-1g, Radix Salviae Miltiorrhizae 15-20g, Herba Solani Nigri 10-13g, Fructus Schisandrae Chinensis 10-15g,
Herba Abri 15-20g, Radix Sophorae Tonkinensis 5-8g, Rhizoma Paridis 12-15g, Radix Astragali 15-35g,
Cordyceps 8-15g.
3. as controlling the preparation method of Chinese medicine of hepatitis B, liver cirrhosis as described in the claim 2, it is characterized in that the component of crude drug and weight proportion thereof are: Bufo siccus 7g, ground beetle 12g, Hirudo 5g, Ganoderma 15g, Radix Paeoniae Alba 13g, Carapax et Plastrum Testudinis 15g, Radix Notoginseng 10g, Carapax Trionycis 20g, Formica fusca 8g, Rhizoma Polygoni Cuspidati 12g, Herba Taraxaci 20g, Rhizoma Atractylodis Macrocephalae 17g, Mylabris 1g, Radix Salviae Miltiorrhizae 15g, Herba Solani Nigri 13g, Fructus Schisandrae Chinensis 15g, Herba Abri 15g, Radix Sophorae Tonkinensis 5g, Rhizoma Paridis 12g, Radix Astragali 15g, Cordyceps 8g.
4. as the preparation method preparation of the Chinese medicine composition of controlling hepatitis B, liver cirrhosis as described in one of claim 1-3
5. as the Chinese medicine of the preparation method preparation of the Chinese medicine composition of controlling hepatitis B, liver cirrhosis as described in one of claim 1-3, make common dosage form by the pharmaceutics common method: electuary, tablet, oral liquid, honeyed pill, the watered pill, capsule.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103223131A (en) * | 2013-05-13 | 2013-07-31 | 殷广全 | Liver disease drug |
| CN104587438A (en) * | 2015-02-04 | 2015-05-06 | 蔡炜 | Medicine for treating hepatitis B |
-
2006
- 2006-04-28 CN CNA2006100766637A patent/CN1876062A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103223131A (en) * | 2013-05-13 | 2013-07-31 | 殷广全 | Liver disease drug |
| CN103223131B (en) * | 2013-05-13 | 2014-10-08 | 殷广全 | Liver disease drug |
| CN104587438A (en) * | 2015-02-04 | 2015-05-06 | 蔡炜 | Medicine for treating hepatitis B |
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