CN1875004A - 那维啶酰胺衍生物的拆分 - Google Patents
那维啶酰胺衍生物的拆分 Download PDFInfo
- Publication number
- CN1875004A CN1875004A CNA2004800276266A CN200480027626A CN1875004A CN 1875004 A CN1875004 A CN 1875004A CN A2004800276266 A CNA2004800276266 A CN A2004800276266A CN 200480027626 A CN200480027626 A CN 200480027626A CN 1875004 A CN1875004 A CN 1875004A
- Authority
- CN
- China
- Prior art keywords
- mixing solutions
- bromamide
- alcohol
- lycoremine
- enantiomorph
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Description
Claims (14)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50646903P | 2003-09-26 | 2003-09-26 | |
US60/506,469 | 2003-09-26 | ||
PCT/US2004/031936 WO2005030713A2 (en) | 2003-09-26 | 2004-09-27 | Resolution of a narwedine amide derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1875004A true CN1875004A (zh) | 2006-12-06 |
CN1875004B CN1875004B (zh) | 2010-06-23 |
Family
ID=34393160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2004800276266A Expired - Fee Related CN1875004B (zh) | 2003-09-26 | 2004-09-27 | 那维啶酰胺衍生物的拆分 |
Country Status (9)
Country | Link |
---|---|
US (1) | US7307162B2 (zh) |
EP (1) | EP1670767B2 (zh) |
JP (1) | JP5020633B2 (zh) |
CN (1) | CN1875004B (zh) |
AU (1) | AU2004276354B2 (zh) |
CA (1) | CA2540248C (zh) |
IL (1) | IL174551A0 (zh) |
NZ (1) | NZ546768A (zh) |
WO (1) | WO2005030713A2 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090253654A1 (en) | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
CA2683098C (en) * | 2007-04-12 | 2014-03-18 | Scinopharm Taiwan Ltd. | Process for making galantamine |
ES2463715T3 (es) | 2008-04-14 | 2014-05-29 | Neurodyn Life Sciences Inc. | Derivados de galantamina como profármacos para el tratamiento de enfermedades del cerebro humano |
WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
BG66818B1 (bg) | 2013-03-07 | 2019-01-31 | Berbee Beheer B. V. | Състав на екстракт от hippeastrum papilio за производство на лекарствени средства и хранителни добавки |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BG28325A1 (en) * | 1978-11-21 | 1980-04-15 | Vlakhov | Method of obtaining of enons navedine type and their derivatives |
US4290862A (en) * | 1979-11-14 | 1981-09-22 | Edinen Centar P Chimia | Method for the preparation of narwedine-type enones |
US5428159A (en) | 1994-04-08 | 1995-06-27 | Ciba-Geigy Corporation | Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine |
US6407229B1 (en) * | 1994-10-21 | 2002-06-18 | Sanochemia Pharmazeutika Ag | Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2] benzazapine |
GB9506843D0 (en) * | 1995-04-03 | 1995-05-24 | Chiroscience Ltd | Oxidative process and products thereof |
US6018043A (en) * | 1995-04-06 | 2000-01-25 | Janssen Pharmaceutica, N.V. | Process for preparing galanthamine derivatives by asymmetric reduction |
GB9707413D0 (en) * | 1997-04-11 | 1997-05-28 | Chiroscience Ltd | Process |
-
2004
- 2004-09-27 JP JP2006528320A patent/JP5020633B2/ja not_active Expired - Fee Related
- 2004-09-27 CN CN2004800276266A patent/CN1875004B/zh not_active Expired - Fee Related
- 2004-09-27 US US10/951,748 patent/US7307162B2/en active Active
- 2004-09-27 CA CA2540248A patent/CA2540248C/en not_active Expired - Fee Related
- 2004-09-27 EP EP04789228.6A patent/EP1670767B2/en not_active Not-in-force
- 2004-09-27 AU AU2004276354A patent/AU2004276354B2/en not_active Ceased
- 2004-09-27 NZ NZ546768A patent/NZ546768A/en not_active IP Right Cessation
- 2004-09-27 WO PCT/US2004/031936 patent/WO2005030713A2/en active Search and Examination
-
2006
- 2006-03-26 IL IL174551A patent/IL174551A0/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US7307162B2 (en) | 2007-12-11 |
CN1875004B (zh) | 2010-06-23 |
EP1670767A4 (en) | 2007-08-29 |
EP1670767A2 (en) | 2006-06-21 |
NZ546768A (en) | 2009-07-31 |
EP1670767B2 (en) | 2014-10-29 |
IL174551A0 (en) | 2006-08-20 |
AU2004276354B2 (en) | 2009-07-09 |
US20050070522A1 (en) | 2005-03-31 |
EP1670767B1 (en) | 2011-08-24 |
AU2004276354A1 (en) | 2005-04-07 |
CA2540248A1 (en) | 2005-04-07 |
WO2005030713A3 (en) | 2006-01-26 |
CA2540248C (en) | 2010-12-07 |
WO2005030713A2 (en) | 2005-04-07 |
JP5020633B2 (ja) | 2012-09-05 |
JP2007506794A (ja) | 2007-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: SCINOPHARM TAIWAN LTD. Free format text: FORMER OWNER: SCHLOEMER GEORGE Effective date: 20070803 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20070803 Address after: Tainan City, Taiwan, China Applicant after: Scinopharm Taiwan, Ltd. Address before: American Colorado Applicant before: Scinopharm Taiwan Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100623 Termination date: 20200927 |
|
CF01 | Termination of patent right due to non-payment of annual fee |