CN1874766A - 神经激肽拮抗剂在尿失禁治疗中的用途 - Google Patents

神经激肽拮抗剂在尿失禁治疗中的用途 Download PDF

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Publication number
CN1874766A
CN1874766A CNA2004800316761A CN200480031676A CN1874766A CN 1874766 A CN1874766 A CN 1874766A CN A2004800316761 A CNA2004800316761 A CN A2004800316761A CN 200480031676 A CN200480031676 A CN 200480031676A CN 1874766 A CN1874766 A CN 1874766A
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CN
China
Prior art keywords
phenyl
hydrogen
methyl
formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800316761A
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English (en)
Chinese (zh)
Inventor
P·W·格鲁
K·H·麦卡利斯特
E·韦伯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34520229&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1874766(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1874766A publication Critical patent/CN1874766A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CNA2004800316761A 2003-10-27 2004-10-26 神经激肽拮抗剂在尿失禁治疗中的用途 Pending CN1874766A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51479103P 2003-10-27 2003-10-27
US60/514,791 2003-10-27

Publications (1)

Publication Number Publication Date
CN1874766A true CN1874766A (zh) 2006-12-06

Family

ID=34520229

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800316761A Pending CN1874766A (zh) 2003-10-27 2004-10-26 神经激肽拮抗剂在尿失禁治疗中的用途

Country Status (9)

Country Link
US (1) US7776851B2 (enExample)
EP (2) EP2158910A1 (enExample)
JP (1) JP2007509184A (enExample)
CN (1) CN1874766A (enExample)
AU (1) AU2004283038B9 (enExample)
BR (1) BRPI0415923A (enExample)
CA (1) CA2543552A1 (enExample)
MX (1) MXPA06004688A (enExample)
WO (1) WO2005039563A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1938804A1 (en) * 2006-12-22 2008-07-02 Novartis AG Pharmaceutical formulation comprising neurokinin antagonist

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0593559A1 (en) * 1991-07-05 1994-04-27 MERCK SHARP & DOHME LTD. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
FR2700472B1 (fr) * 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
MY132550A (en) * 1996-08-22 2007-10-31 Novartis Ag Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists
GB0015246D0 (en) * 2000-06-22 2000-08-16 Astrazeneca Ab Method for the treatment of urinary incontinence
US6664253B2 (en) * 2000-10-17 2003-12-16 Boehringer Ingelheim Pharma Kg Neurokinin antagonists
WO2002051440A1 (en) * 2000-12-22 2002-07-04 Takeda Chemical Industries, Ltd. Combination drugs
JP4175113B2 (ja) 2001-03-14 2008-11-05 小野薬品工業株式会社 Ｅｐ１アンタゴニストを有効成分として含有するうつ病の治療剤
MXPA04006571A (es) * 2002-01-18 2004-10-04 Kyorin Seiyaku Kk Derivado de pirimidina biciclica fusionada.
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds
CA2479277A1 (en) * 2002-03-26 2003-10-02 Kyorin Pharmaceutical Co., Ltd. Fused bicyclic pyrimidine derivatives
KR20040099367A (ko) * 2002-03-26 2004-11-26 교린 세이야꾸 가부시키 가이샤 타키키닌 수용체 길항제로서의 축합 바이사이클릭 피리딘 유도체

Also Published As

Publication number Publication date
US7776851B2 (en) 2010-08-17
AU2004283038A1 (en) 2005-05-06
CA2543552A1 (en) 2005-05-06
JP2007509184A (ja) 2007-04-12
EP1686985A2 (en) 2006-08-09
AU2004283038B9 (en) 2008-04-24
AU2004283038B2 (en) 2008-01-31
US20070149504A1 (en) 2007-06-28
BRPI0415923A (pt) 2006-12-26
EP2158910A1 (en) 2010-03-03
WO2005039563A2 (en) 2005-05-06
WO2005039563A3 (en) 2005-06-30
MXPA06004688A (es) 2006-07-05

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Application publication date: 20061206