CN1872339A

CN1872339A - Soakage of medication for treating arthritis

Info

Publication number: CN1872339A
Application number: CN 200610010230
Authority: CN
Inventors: 文彦春; 王玉梅
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-06-28
Filing date: 2006-06-28
Publication date: 2006-12-06
Anticipated expiration: 2026-06-28
Also published as: CN100417415C

Abstract

A medicine for treating the arthrititides of spine and limbs by infiltration injection therapy is prepared from energy mixture, compound osteopeptide, gentamycin and lidocaine through proportional mixing.

Description

Soak into the medicine of treatment of arthritis

(1) technical field

What the present invention relates to is a kind of pharmaceutical composition, specifically a kind of pharmaceutical composition of treatment of arthritis.

(2) background technology

Arthritis is meant that the hypertrophic teoarthropathy, regression, periarticular soft tissues adhesion, the contracture that cause after long-term scorching change of periarticular soft tissues or the wound are a big class disease of main performance, be commonly encountered diseases, the frequently-occurring disease of each hospital outpatient, its prevalence height, disability rate are also very high.At present Chinese and western medicine has been carried out a large amount of research on this type of disease of treatment, but all seems on therapeutic effect and be pale and weak, and has caused patient's economic loss and body and mind misery, finally causes joint deformity.Chinese scholars belongs to the rheumatism category with this class disease at present, its cause of disease complexity, no matter be that infect, immunity, metabolic, endocrine and geographical environment etc., its pathological change is histiocyte inflammatory hyperemia, edema, oozes out and cell infiltration, finally causes joint hyperplasia, regression, soft tissue adhesion, contracture, the dysfunction of getting involved.

(3) summary of the invention

The object of the invention is to provide a kind of medicine that arthritis is had the infiltration treatment of arthritis of excellent curative.

The object of the present invention is achieved like this: it is the resulting mixture of mixed according to Energy mixture 90-100 unit, complex bone peptide 70-80mg, gentamycin 7.5-8 ten thousand units and 2% lignocaine 5-6mg.

Energy mixture among the present invention is the coenzyme of histiocyte ethane reaction, participates in sugar in the body, fat, protein and nucleotide metabolism, becomes or the cellular enzymes all kinds of diseases that cause that go down in damage back have therapeutic effect histiocyte is scorching.The antiinflammatory action of gentamycin is strong, and is splendid to each bacteroid action effect, is difficult for producing drug resistance.But the pathological changes of complex bone peptide antagonism nonspecific inflammation is quickened partial blood circulation and metabolite and is removed, and improves weary oxygen of pathological tissues and metabolite and piles up the old goldenrain tree that causes.Lignocaine is a local anaesthetics, can stablize the cell membrane of nerve fiber, makes action potential can't conduct, make the neural sensation function to be blocked, to remove vasospasm, thereby interrupts lesion pain conduction vicious cycle, reaches therapeutic purposes.

The present invention mixes these compositions, row articular cavity and the treatment of synovial membrane capsule infiltration injecting, make medicine can directly reach the histiocyte of getting involved, and and receptors bind, cellular energy replenished, the metabolism of active cell, thereby improve the activity and the permeability of cellular enzymes, antagonism the acute and chronic nonspecific inflammatory reaction, suppress and the blocking-up virulence factor to histiocytic infringement, the reaction of elimination local inflammation finally plays a role by energy coupling.Do not find toxic and side effects, the reliable cure rate height of curative effect through the clinical practice test.Spinal column and extremities joint inflammation had significant curative effect.

Be the clinical trial structure of product of the present invention below:

1, treatment scapulohumeral periarthritis

This group is totally 43 examples, wherein male 26 examples, women 17 examples; Age 38-64 year, account for 80% more than 50 years old; Medical history 1-3 month; Case is one-sided.With the capable biceps brachii m. stndon sheath of product of the present invention, triceps muscle and supraspinatus synovial bursa, each infiltration injecting 2ml of triangular muscle synovial bursa.Through three infiltration injecting treatments, injected once in average 5 days, 37 examples of fully recovering, effective 6 examples, the shoulder joint edema is obviously improved, and does not see invalid case, and observing had 2 example recurrences in 1 year.

2, sacroiliac joint bursitis

This group is totally 25 examples, wherein male 16 examples, women 9 examples; Age 32-58 year; Medical history 1-2 month, do not have obvious inducement and account for 80%, what trauma history was arranged accounts for 20%.Reach injection 2ml behind the sclerotin, Ipsilateral sacroiliac joint synovial bursa each injection 3ml up and down with the capable waist 4-5 of product of the present invention Ipsilateral transverse process flesh starting point, needle point.Fully recover 19 examples, effective 6 examples are on average injected 3 times, and per 5 days once, and 4 examples are answered the seasonal variations recurrence.

3, gonarthromeningitis

This group is totally 44 examples, wherein male 27 examples, women 17 examples; Age 32-76 year, medical history 2-3 week.With the capable knee joint suprapatellar bursa of medicine of the present invention injectable drug 5ml, injected once in per 5 days, average 3 times, 36 examples of fully recovering, produce effects 4 examples, clinical symptom remission 3 examples, invalid 1 example is observed 2 example recurrences with examining.

4, the palm refers to and refers to a rheumatoid arthritis

This group is totally 7 examples, wherein male 3 examples, women 4 examples, and age 24-40 year, medical history 3-6, case is both hands and refers to more.With the capable metacarpophalangeal joints of getting involved of product of the present invention and each injection 1ml of interphalangeal joint chamber, be administered once average 2 times in per 5 days.5 examples of fully recovering, produce effects 2 examples are followed up a case by regular visits to and are recurred 2 examples half a year.

(4) specific embodiment

For a more detailed description to the present invention for example below in conjunction with accompanying drawing:

Ratio according to Energy mixture 90-100 unit, complex bone peptide 70-80mg, gentamycin 7.5-8 ten thousand units and 2% lignocaine 5-6mg is made mixture with each raw material mix homogeneously.Its best proportioning is Energy mixture 100 units, complex bone peptide 75mg, gentamycin 80,000 units, 2% lignocaine 5mg.Wherein said Energy mixture is the mixture of 303 adenosines, coenzyme A and chicken glycosides, and its mixed proportion is generally 1: 1: 1.

Get 1 in every mixture mixture that contains Energy mixture 100 units, complex bone peptide 75mg, gentamycin 80,000 units, 2% lignocaine 5mg, row 3 the injections of synovial bursa around articular cavity and the joint of getting involved, average injection every day is once injected three times altogether.

Claims

1, a kind of medicine that soaks into treatment of arthritis is characterized in that: it is the resulting mixture of mixed according to Energy mixture 90-100 unit, complex bone peptide 70-80mg, gentamycin 7.5-8 ten thousand units and 2% lignocaine 5-6mg.

2, the medicine of infiltration treatment of arthritis according to claim 1 is characterized in that: it is the mixture of Energy mixture 100 units, complex bone peptide 75mg, gentamycin 80,000 units, 2% lignocaine 5mg.