CN100417415C - Soakage of medication for treating arthritis - Google Patents
Soakage of medication for treating arthritis Download PDFInfo
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- CN100417415C CN100417415C CNB2006100102301A CN200610010230A CN100417415C CN 100417415 C CN100417415 C CN 100417415C CN B2006100102301 A CNB2006100102301 A CN B2006100102301A CN 200610010230 A CN200610010230 A CN 200610010230A CN 100417415 C CN100417415 C CN 100417415C
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Abstract
The present invention provides medicine for treating arthritis in an immersion mode, which is characterized in that the medicine is a mixture comprising 90 to 100 units of energy compound agent, 70 to 80 mg of compound bone peptide, 75, 000 to 80, 000 units of gentamicin and 5 to 6 mg of 2% lidocaine. The medicine of the present invention is used for treating the articular cavity and the bursa synovialis in an immersion and injection mode so that the medicine can directly reach affected histocyte and is combined with receptors for supplementing cell energy and activating the metabolism of cells. Therefore, the activity and the permeability of ectocellular enzymes are improved, acute and chronic non-specificity inflammatory reactions are resisted, damage of pathogenic factors to histiocyte is inhibited and prevented, and partial inflammatory reactions are eliminated. Finally, the medicine performs functions by means of energy coupling. Experiments in clinical application show that the medicine has the advantages of no side effect, reliable curative effect and high cure rate. The medicine has obvious curative effects on arthritis on the vertebral column and limbs.
Description
(1) technical field
What the present invention relates to is a kind of pharmaceutical composition, specifically a kind of pharmaceutical composition of treatment of arthritis.
(2) background technology
Arthritis is meant that the hypertrophic teoarthropathy, regression, periarticular soft tissues adhesion, the contracture that cause after long-term scorching change of periarticular soft tissues or the wound are a big class disease of main performance, be commonly encountered diseases, the frequently-occurring disease of each hospital outpatient, its prevalence height, disability rate are also very high.At present Chinese and western medicine has been carried out a large amount of research on this type of disease of treatment, but all seems on therapeutic effect and be pale and weak, and has caused patient's economic loss and body and mind misery, finally causes joint deformity.Chinese scholars belongs to the rheumatism category with this class disease at present, its cause of disease complexity, no matter be that infect, immunity, metabolic, endocrine and geographical environment etc., its pathological change is histiocyte inflammatory hyperemia, edema, oozes out and cell infiltration, finally causes joint hyperplasia, regression, soft tissue adhesion, contracture, the dysfunction of getting involved.
(3) summary of the invention
The object of the invention is to provide a kind of medicine that arthritis is had the infiltration treatment of arthritis of excellent curative.
The object of the present invention is achieved like this: it is the resulting mixture of mixed according to Energy mixture 90-100 unit, complex bone peptide 70-80mg, gentamycin 7.5-8 ten thousand units and 2% lignocaine 5-6mg, and described Energy mixture is adenosine triphosphate, coenzyme A and 1: 1: 1 mixture of inosine.
Energy mixture among the present invention is the coenzyme of histiocyte ethane reaction, participates in sugar in the body, fat, protein and nucleotide metabolism, becomes or the cellular enzymes all kinds of diseases that cause that go down in damage back have therapeutic effect histiocyte is scorching.The antiinflammatory action of gentamycin is strong, and is splendid to each bacteroid action effect, is difficult for producing drug resistance.But the pathological changes of complex bone peptide antagonism nonspecific inflammation is quickened partial blood circulation and metabolite and is removed, and improves weary oxygen of pathological tissues and metabolite and piles up the old goldenrain tree that causes.Lignocaine is a local anaesthetics, can stablize the cell membrane of nerve fiber, makes action potential can't conduct, make the neural sensation function to be blocked, to remove vasospasm, thereby interrupts lesion pain conduction vicious cycle, reaches therapeutic purposes.
The present invention mixes these compositions, row articular cavity and the treatment of synovial membrane capsule infiltration injecting, make medicine can directly reach the histiocyte of getting involved, and and receptors bind, cellular energy replenished, the metabolism of active cell, thereby improve the activity and the permeability of cellular enzymes, antagonism the acute and chronic nonspecific inflammatory reaction, suppress and the blocking-up virulence factor to histiocytic infringement, the reaction of elimination local inflammation finally plays a role by energy coupling.Do not find toxic and side effects, the reliable cure rate height of curative effect through the clinical practice test.Spinal column and extremities joint inflammation had significant curative effect.
Be the clinical trial structure of product of the present invention below:
1, treatment scapulohumeral periarthritis
This group is totally 43 examples, wherein male 26 examples, women 17 examples; Age 38-64 year, account for 80% more than 50 years old; Medical history 1-3 month; Case is one-sided.With the capable biceps brachii m. stndon sheath of product of the present invention, triceps muscle and supraspinatus synovial bursa, each infiltration injecting 2ml of triangular muscle synovial bursa.Through three infiltration injecting treatments, injected once in average 5 days, 37 examples of fully recovering, effective 6 examples, the shoulder joint edema is obviously improved, and does not see invalid case, and observing had 2 example recurrences in 1 year.
2, sacroiliac joint bursitis
This group is totally 25 examples, wherein male 16 examples, women 9 examples; Age 32-58 year; Medical history 1-2 month, do not have obvious inducement and account for 80%, what trauma history was arranged accounts for 20%.Reach injection 2ml behind the sclerotin, Ipsilateral sacroiliac joint synovial bursa each injection 3ml up and down with the capable waist 4-5 of product of the present invention Ipsilateral transverse process flesh starting point, needle point.Fully recover 19 examples, effective 6 examples are on average injected 3 times, and per 5 days once, and 4 examples are answered the seasonal variations recurrence.
3, gonarthromeningitis
This group is totally 44 examples, wherein male 27 examples, women 17 examples; Age 32-76 year, medical history 2-3 week.With the capable knee joint suprapatellar bursa of medicine of the present invention injectable drug 5ml, injected once in per 5 days, average 3 times, 36 examples of fully recovering, produce effects 4 examples, clinical symptom remission 3 examples, invalid 1 example is observed 2 example recurrences with examining.
4, the palm refers to and refers to a rheumatoid arthritis
This group is totally 7 examples, wherein male 3 examples, women 4 examples, and age 24-40 year, medical history 3-6, case is both hands and refers to more.With the capable metacarpophalangeal joints of getting involved of product of the present invention and each injection 1ml of interphalangeal joint chamber, be administered once average 2 times in per 5 days.5 examples of fully recovering, produce effects 2 examples are followed up a case by regular visits to and are recurred 2 examples half a year.
(4) specific embodiment
For a more detailed description to the present invention for example below in conjunction with accompanying drawing:
Ratio according to Energy mixture 90-100 unit, complex bone peptide 70-80mg, gentamycin 7.5-8 ten thousand units and 2% lignocaine 5-6mg is made mixture with each raw material mix homogeneously.Its best proportioning is Energy mixture 100 units, complex bone peptide 75mg, gentamycin 80,000 units, 2% lignocaine 5mg.Wherein said Energy mixture is the mixture of adenosine triphosphate, coenzyme A and inosine, and its mixed proportion is generally 1: 1: 1.
Get 1 in every mixture mixture that contains Energy mixture 100 units, complex bone peptide 75mg, gentamycin 80,000 units, 2% lignocaine 5mg, row 3 the injections of synovial bursa around articular cavity and the joint of getting involved, average injection every day is once injected three times altogether.
Claims (2)
1. medicine that soaks into treatment of arthritis, it is characterized in that: it is the resulting mixture of mixed according to Energy mixture 90-100 unit, complex bone peptide 70-80mg, gentamycin 7.5-8 ten thousand units and 2% lignocaine 5-6mg, and described Energy mixture is adenosine triphosphate, coenzyme A and 1: 1: 1 mixture of inosine.
2. the medicine of infiltration treatment of arthritis according to claim 1, it is characterized in that: it is the mixture of Energy mixture 100 units, complex bone peptide 75mg, gentamycin 80,000 units, 2% lignocaine 5mg, and described Energy mixture is adenosine triphosphate, coenzyme A and 1: 1: 1 mixture of inosine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100102301A CN100417415C (en) | 2006-06-28 | 2006-06-28 | Soakage of medication for treating arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100102301A CN100417415C (en) | 2006-06-28 | 2006-06-28 | Soakage of medication for treating arthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1872339A CN1872339A (en) | 2006-12-06 |
| CN100417415C true CN100417415C (en) | 2008-09-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100102301A Expired - Fee Related CN100417415C (en) | 2006-06-28 | 2006-06-28 | Soakage of medication for treating arthritis |
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| CN (1) | CN100417415C (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998046253A1 (en) * | 1997-04-15 | 1998-10-22 | Astra Aktiebolag (Publ) | Use of cartilage oligomeric matrix protein for the treatment of rheumatoid arthritis |
| WO2003041724A1 (en) * | 2001-11-13 | 2003-05-22 | Alcon, Inc. | Use of a mixture of sodium hyaluronate and chondroitin sulfate for the treatment of osteoarthritis |
| WO2005002611A1 (en) * | 2003-06-27 | 2005-01-13 | Indena S.P.A. | Formulations for the treatment of arhritis conditions |
| CN1569218A (en) * | 2004-01-12 | 2005-01-26 | 江勇 | Bone peptide for injection and its preparation method |
| CN1579541A (en) * | 2004-02-23 | 2005-02-16 | 江卫世 | Compound bone peptide for injection and its preparation process |
| CN1679609A (en) * | 2005-02-03 | 2005-10-12 | 北京阜康仁生物制药科技有限公司 | Compound energy mistura fat-soluble vitamins adult preparation and use thereof |
-
2006
- 2006-06-28 CN CNB2006100102301A patent/CN100417415C/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998046253A1 (en) * | 1997-04-15 | 1998-10-22 | Astra Aktiebolag (Publ) | Use of cartilage oligomeric matrix protein for the treatment of rheumatoid arthritis |
| WO2003041724A1 (en) * | 2001-11-13 | 2003-05-22 | Alcon, Inc. | Use of a mixture of sodium hyaluronate and chondroitin sulfate for the treatment of osteoarthritis |
| WO2005002611A1 (en) * | 2003-06-27 | 2005-01-13 | Indena S.P.A. | Formulations for the treatment of arhritis conditions |
| CN1569218A (en) * | 2004-01-12 | 2005-01-26 | 江勇 | Bone peptide for injection and its preparation method |
| CN1579541A (en) * | 2004-02-23 | 2005-02-16 | 江卫世 | Compound bone peptide for injection and its preparation process |
| CN1679609A (en) * | 2005-02-03 | 2005-10-12 | 北京阜康仁生物制药科技有限公司 | Compound energy mistura fat-soluble vitamins adult preparation and use thereof |
Non-Patent Citations (2)
| Title |
|---|
| 降钙素与复方骨肽联合治疗骨质疏松症的临床观察. 黄剑锋等.贵阳医学院学报，第30卷第4期. 2005 |
| 降钙素与复方骨肽联合治疗骨质疏松症的临床观察. 黄剑锋等.贵阳医学院学报，第30卷第4期. 2005 * |
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| Publication number | Publication date |
|---|---|
| CN1872339A (en) | 2006-12-06 |
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Granted publication date: 20080910 Termination date: 20110628 |