CN100589837C

CN100589837C - Externally used medicine for treating rheumatism and rheumatism ache and method for preparing the same

Info

Publication number: CN100589837C
Application number: CN200710054990A
Authority: CN
Inventors: 晁平显
Original assignee: Individual
Current assignee: Individual
Priority date: 2007-08-17
Filing date: 2007-08-17
Publication date: 2010-02-17
Anticipated expiration: 2027-08-17
Also published as: CN101112590A

Abstract

The present invention provides an externally applied drug for treating rheumatism and rheumatism pains and the preparation method, the externally applied drug is prepared by the following pharmaceutical raw materials: camphor, borneol, borax, calcined alum, Szechuan pepper, white mustard seed, turmeric, medicinal sulfate magnesium and 95 percent alcohol; the preparation method of the externally applied drug is that: the camphor, borneol, borax and calcined alum are taken and soaked in the 95 percent alcohol, and the soaking time is more than 7 days; the Szechuan pepper, white mustard seed andturmeric are taken and soaked in the 95 percent alcohol, the soaking time is more than 7 days; the soaked mixture is mixed, the medicinal sulfate magnesium is added, and then the even agitating is carried out for use. The drug of the present invention has reliable efficacy and fewer side effects, the diseases are not likely to recur after the cure; the present invention has significant efficacy ofstopping pain, and the sustainable use of the present invention can cure the rheumatoid diseases gradually.

Description

External used medicine of treatment rheumatoid and rheumatoid pain and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically, related to a kind of external used medicine for the treatment of rheumatoid and rheumatoid pain and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Rheumatism is perplexing people's health for a long time, has brought very big misery for people's health; Especially rheumatoid arthritis in, sickness rate is higher in the elderly population, sees with the women more, this disease is to refer to little redness and swelling of joints, pain such as (toe), wrist, ankle, limitation of activity is a cardinal symptom, sometimes also can involve big joint such as elbow, knee joint, hip, shoulder, severe patient can cause limitation of activity, joint deformity.

The tcm product of existing treatment rheumatism, rheumatalgia is many, but all similar aspect prescription, Therapeutic Method, effect, cures the symptoms, not the disease especially easily recurrence after patient's drug withdrawal.

In order to solve this difficult problem of rheumatism and rheumatalgia, people are constantly exploring and are studying, and however, the therapeutic effect of existing Chinese medicine preparation still can not be satisfactory.

Summary of the invention

The objective of the invention is at the deficiency of existing Chinese medicine preparation in treatment rheumatism and rheumatism pain disease, provide that a kind of side effect is little, the curative effect that relieves the pain is reliable, cure the back is difficult for the treatment rheumatoid of recurrence and the external used medicine of rheumatoid pain, and a kind of preparation method of this treatment rheumatoid and rheumatoid pain medicine also is provided.

For achieving the above object, the invention provides a kind of external used medicine for the treatment of rheumatoid and rheumatoid pain, this medicine is made by following raw medicines in parts by weight: Camphora 1-5 part, Borneolum Syntheticum 1-3 part, Borax 1-2 part, dried Alumen 2-5 part, Fructus Zanthoxyli 1-2 part, Semen Sinapis Albae 1-3 part, Rhizoma Curcumae Longae 1-2 part, medicinal sulfate magnesium 1-2 part, 95% ethanol 40-100 part.

Based on above-mentioned, this medicine is made by following raw medicines in parts by weight: Camphora 2-4 part, Borneolum Syntheticum 1.5-2.5 part, Borax 1.2-1.8 part, dried Alumen 2.5-4.5 part, Fructus Zanthoxyli 1.2-1.8 part, Semen Sinapis Albae 1.2-2.5 part, Rhizoma Curcumae Longae 1.2-1.8 part, medicinal sulfate magnesium 1.2-1.6 part, 95% ethanol 50-80 part.

Based on above-mentioned, this medicine is made by following raw medicines in parts by weight: Camphora 2.5-3.5 part, Borneolum Syntheticum 1.8-2.2 part, Borax 1.5-1.8 part, dried Alumen 3-4.2 part, Fructus Zanthoxyli 1.5-1.6 part, Semen Sinapis Albae 1.5-2.4 part, Rhizoma Curcumae Longae 1.4-1.7 part, medicinal sulfate magnesium 1.3-1.5 part, 95% ethanol 60-80 part.

Based on above-mentioned, this medicine is made by following raw medicines in parts by weight: 3 parts of Camphoras, 2 parts of Borneolum Syntheticums, 1.6 parts of Boraxs, 3.5 parts of dried Alumens, 1.6 parts of Fructus Zanthoxylis, 1.8 parts of Semen Sinapis Albaes, 1.5 parts in Rhizoma Curcumae Longae, 1.5 parts of medicinal sulfate magnesium, 80 parts of 95% ethanol.

Preparation method based on the external used medicine of above-described treatment rheumatoid and rheumatoid pain may further comprise the steps:

Step 1, by weight, take off the row crude drug: Camphora 1-5 part, Borneolum Syntheticum 1-3 part, Borax 1-2 part, dried Alumen 2-5 part, then, be soaked in 95% ethanol of 20-50 part, soak time is more than 7 days;

Step 2, by weight, take off the row crude drug: Fructus Zanthoxyli 1-2 part, Semen Sinapis Albae 1-3 part, Rhizoma Curcumae Longae 1-2 part, then, be soaked in 95% ethanol of 20-50 part, soak time is more than 7 days;

Step 3, the final gained immersion mixture of step 1 and step 2 is mixed;

Step 4, in the final gained immersion mixture of step 3, add medicinal sulfate magnesium 1-2 part;

Step 5, the final gained immersion mixture of step 4 is stirred, get final product.

Medicine effect of the present invention is reliable, and side effect is little, cures the back and is difficult for recurrence, has the analgesic remarkable efficacy, continues to use, and can cure rheumatoid disease gradually.

The specific embodiment

The inventor passes through long term test and courageously gropes, and on the basis of great number tested data, sum up various components and the proportioning thereof draw medicine of the present invention, for describing the proportion relation of material medicine of the present invention in detail, reach the therapeutic effect that fully manifests medicine of the present invention, now provide its concrete embodiment:

Embodiment one

A kind of external used medicine for the treatment of rheumatism and rheumatalgia, this medicine is made by following raw medicines in parts by weight: 1 part of Camphora, 1 part of Borneolum Syntheticum, 1 part of Borax, 2 parts of dried Alumens, 1 part of Fructus Zanthoxyli, 1 part of Semen Sinapis Albae, 1 part in Rhizoma Curcumae Longae, 1 part of medicinal sulfate magnesium, 40 parts of 95% ethanol.

Preparation method based on the external used medicine of above-described treatment rheumatism and rheumatalgia may further comprise the steps:

Step 1, by weight, take off the row crude drug: 1 part of Camphora, 1 part of Borneolum Syntheticum, 1 part of Borax, 2 parts of dried Alumens, then, be soaked in 20 parts 95% ethanol, soak time is 12 days;

Step 2, by weight, take off the row crude drug: 1 part of Fructus Zanthoxyli, 1 part of Semen Sinapis Albae, 1 part in Rhizoma Curcumae Longae, then, be soaked in 20 parts 95% ethanol, soak time is 10 days;

Step 3, the final gained immersion mixture of step 1 and step 2 is mixed;

Step 4, in the final gained immersion mixture of step 3, add 1 part of medicinal sulfate magnesium;

Embodiment two

Based on above-mentioned, the difference of present embodiment and embodiment one mainly is: this medicine is made by following raw medicines in parts by weight: 5 parts of Camphoras, 3 parts of Borneolum Syntheticums, 2 parts of Boraxs, 5 parts of dried Alumens, 2 parts of Fructus Zanthoxylis, 3 parts of Semen Sinapis Albaes, 2 parts in Rhizoma Curcumae Longae, 2 parts of medicinal sulfate magnesium, 100 parts of 95% ethanol.

Step 1, by weight, take off the row crude drug: 5 parts of Camphoras, 3 parts of Borneolum Syntheticums, 2 parts of Boraxs, 5 parts of dried Alumens, then, be soaked in 50 parts 95% ethanol, soak time is 15 days;

Step 2, by weight, take off the row crude drug: 2 parts of Fructus Zanthoxylis, 3 parts of Semen Sinapis Albaes, 2 parts in Rhizoma Curcumae Longae, then, be soaked in 50 parts 95% ethanol, soak time is 15 days;

Step 3, the final gained immersion mixture of step 1 and step 2 is mixed;

Step 4, in the final gained immersion mixture of step 3, add 2 parts of medicinal sulfate magnesium;

Embodiment three

Based on above-mentioned, the difference of present embodiment and embodiment one mainly is: this medicine is made by following raw medicines in parts by weight: 3 parts of Camphoras, 2 parts of Borneolum Syntheticums, 1.6 parts of Boraxs, 3.5 parts of dried Alumens, 1.6 parts of Fructus Zanthoxylis, 1.8 parts of Semen Sinapis Albaes, 1.5 parts in Rhizoma Curcumae Longae, 1.5 parts of medicinal sulfate magnesium, 80 parts of 95% ethanol.

Step 1, by weight, take off the row crude drug: 3 parts of Camphoras, 2 parts of Borneolum Syntheticums, 1.6 parts of Boraxs, 3.5 parts of dried Alumens, then, be soaked in 40 parts 95% ethanol, soak time is 16 days;

Step 2, by weight, take off the row crude drug: 1.6 parts of Fructus Zanthoxylis, 1.8 parts of Semen Sinapis Albaes, 1.5 parts in Rhizoma Curcumae Longae, then, be soaked in 40 parts 95% ethanol, soak time is 16 days;

Step 3, the final gained immersion mixture of step 1 and step 2 is mixed;

Step 4, in the final gained immersion mixture of step 3, add 1.5 parts of medicinal sulfate magnesium;

In the crude drug of the present invention, Camphora: expelling wind and cold, vital energy regualting and blood circulation-promoting, pain relieving are only overworked; Borneolum Syntheticum: sensible, dispel the heat, make eye bright, pain relieving; Dried Alumen: astringing to arrest bleeding, removing dampness and eliminating phlegm, parasite killing detoxifcation; Borax: heat clearing away, the disease that disappears, detoxifcation, anticorrosion; Fructus Zanthoxyli: warming spleen and stomach for dispelling cold, invigorating the stomach and promoting digestion, promoting blood circulation and detumescence; Semen Sinapis Albae: promoting the circulation of QI eliminating phlegm, cold expelling, reducing swelling and alleviating pain; Rhizoma Curcumae Longae: circulation of qi promoting removing blood stasis with potent drugs, inducing menstruation to relieve menalgia.

More typical case has:

Wang Jumei, 41 years old, the woman, people from Puyang County, Henan suffers from arthralgia 8 wheat harvesting periods, and multi-treatment loses effect, and the rheumatoid symptom is arranged; Symptom: the deadlock in morning is arranged, and knee-joint pain can not normally be walked; After examination in hospital, rheumatoid factor (RF) positive, erythrocyte sedimentation rate is higher, and leukocyte is higher; Be diagnosed as doubtful rheumatoid; Treat, take medicine: tripterygium glycosides sheet, hydroxychloroquine sulfate sheet, methotrexate (once in a week);

After one month, effect is obvious, walks and recovers normal, and arthralgia fades away; But after the drug withdrawal three months, pain progressively begins again to increase the weight of; Continue again to take medicine, and be restored gradually, but drug withdrawal less than 3 months promptly once more repeatedly, makes patient agonizing;

Begin to adopt this Drug therapy in March, 2004, smears this medicine every day in joint, adheres to using January surplus, and pain symptom fades away, and it is relatively more normal to walk, and morning, stiff phenomenon reduced gradually, continued again to use this medicine about 2 months, the symptom complete obiteration; So far had a surplus, and loseed repeatedly in 3 years.

Yellow new recruit, 19 years old, the man, school, Henan university students is because of two swelling and pain in knee, clothes the antibiotic medicine, sx, after repeatedly the outbreak, the whole body arthralgia is learnt through chemical examination, rheumatoid factor (RF) is positive, and two knee joint hydrops, right knee joint are with cyst, and it is difficult to walk, the multi-treatment poor effect;

Go to a doctor in the here of coming at the beginning of July 14 calendar year 2001, suspend schooling half a year, adopt this Drug therapy, smear this medicine every day in joint, adhere to using 2 wheat harvesting periods after, pain symptom fades away, it is relatively more normal to walk, and right knee joint cyst fades away, and two knee joint hydrops reduce gradually, continue again to use this medicine about 4 months, above symptom disappears substantially; The back is gone back to school and is adhered to treatment;

The investigation end of the year in 2006, the patient fully recovers and works, and does not see repeatedly life happiness in 5 years.

Liang Fengqin, 58 years old, the woman, people from Qingfeng County, Henan Province has rheumatoid arthritis history more than two decades, shows as the little arthralgia of finger (toe), and redness is the intermittence outbreak; After the treatment of resisting rheumatoid disease medicine, take a turn for the better; Annual recurrence 4～6 times, each outbreak is from time in about 3～6 weeks that begin to take a turn for the better to Drug therapy; Along with attack times increases, the curative effect of medicine reduces; Over nearly 4 years, outside the little redness and swelling of joints, and joint deformity appears, with spring, outbreak in autumn frequently, the pain increased, and winter in 2002 developed into and can't take care of oneself, and articulations digitorum manus can not stretch, obviously red and swollen, pain is treated no obvious curative effects to immunosuppressant and hormonal medicaments unbearably;

In January, 2003, the patient adopts this Drug therapy, smears this medicine every day in joint, and after adhering to using more than four months, the diseased region redness and swelling of joints disappears, and pain fades away, and range of motion obviously improves, and tenderness reduces; Continue again to use this medicine about 8 months, joint deformity is restored gradually, and above symptom also progressively takes a turn for the better; Short its medication that holds on;

Autumn in 2004, the patient comes the here further consultation, the disease complete obiteration; The investigation second half year in 2006, the patient does not have discomfort, and the mental status is good, does not have outbreak repeatedly, and old age, life was happy, happy.

Cheng Guizhen, 71 years old, the woman, people from Nanyue County, Henan Province, the trick joint deformity, pain unbearably, difficulty in walking, puffiness of face, whenever walk 10 the step, will sit back, squat down the station not, appetite is bad, and will go to hospital to have an intravenous drip every several days;

Accept this Drug therapy in March, 2004, smear this medicine every day in joint, adhere to using 1 wheat harvesting period after, it is more normal to find that the patient walks, the conscious whole body is light, pain symptom disappears in unconsciously to some extent, face's edema fades away, appetite is slowly increasing; Continue to use this medicine about 2 months, disease disappears substantially; Investigation in 2006, the patient can trot out alone, and condition is better, does not have obviously repeatedly.

Therefore, medicine effect of the present invention is reliable, and side effect is little, cures the back and is difficult for recurrence, has the analgesic remarkable efficacy, continues to use, and can cure rheumatism gradually.

Should be noted that at last: above embodiment is only in order to illustrate that technical scheme of the present invention is not intended to limit; Although with reference to preferred embodiment the present invention is had been described in detail, those of ordinary skill in the field are to be understood that: still can make amendment or the part technical characterictic is equal to replacement the specific embodiment of the present invention; And not breaking away from the spirit of technical solution of the present invention, it all should be encompassed in the middle of the technical scheme scope that the present invention asks for protection.

Claims

1, a kind of external used medicine for the treatment of rheumatoid and rheumatoid pain, it is characterized in that this medicine is made by following raw medicines in parts by weight: Camphora 1-5 part, Borneolum Syntheticum 1-3 part, Borax 1-2 part, dried Alumen 2-5 part, Fructus Zanthoxyli 1-2 part, Semen Sinapis Albae 1-3 part, Rhizoma Curcumae Longae 1-2 part, medicinal sulfate magnesium 1-2 part, 95% ethanol 40-100 part.

2, the external used medicine of treatment rheumatoid according to claim 1 and rheumatoid pain, it is characterized in that this medicine is made by following raw medicines in parts by weight: Camphora 2-4 part, Borneolum Syntheticum 1.5-2.5 part, Borax 1.2-1.8 part, dried Alumen 2.5-4.5 part, Fructus Zanthoxyli 1.2-1.8 part, Semen Sinapis Albae 1.2-2.5 part, Rhizoma Curcumae Longae 1.2-1.8 part, medicinal sulfate magnesium 1.2-1.6 part, 95% ethanol 50-80 part.

3, the external used medicine of treatment rheumatoid according to claim 2 and rheumatoid pain, it is characterized in that this medicine is made by following raw medicines in parts by weight: Camphora 2.5-3.5 part, Borneolum Syntheticum 1.8-2.2 part, Borax 1.5-1.8 part, dried Alumen 3-4.2 part, Fructus Zanthoxyli 1.5-1.6 part, Semen Sinapis Albae 1.5-2.4 part, Rhizoma Curcumae Longae 1.4-1.7 part, medicinal sulfate magnesium 1.3-1.5 part, 95% ethanol 60-80 part.

4, the external used medicine of treatment rheumatoid according to claim 1 and rheumatoid pain, it is characterized in that this medicine is made by following raw medicines in parts by weight: 3 parts of Camphoras, 2 parts of Borneolum Syntheticums, 1.6 parts of Boraxs, 3.5 parts of dried Alumens, 1.6 parts of Fructus Zanthoxylis, 1.8 parts of Semen Sinapis Albaes, 1.5 parts in Rhizoma Curcumae Longae, 1.5 parts of medicinal sulfate magnesium, 80 parts of 95% ethanol.

5, the preparation method of the external used medicine of described treatment rheumatoid of claim 1 and rheumatoid pain is characterized in that, may further comprise the steps:

Step 3, the final gained immersion mixture of step 1 and step 2 is mixed;