CN1872096A - Medication for treating liver disease, and preparation method - Google Patents
Medication for treating liver disease, and preparation method Download PDFInfo
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- CN1872096A CN1872096A CNA2006100766069A CN200610076606A CN1872096A CN 1872096 A CN1872096 A CN 1872096A CN A2006100766069 A CNA2006100766069 A CN A2006100766069A CN 200610076606 A CN200610076606 A CN 200610076606A CN 1872096 A CN1872096 A CN 1872096A
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Abstract
A Chinese medicine for treating hepatomegaly, hepatoascites, liver cancer, diabetes, cardiovascular and cerebrovascular diseases and rheumatism is prepared from 9 Chinese-medicinal materials including cordyceps, centipede, leech, ground bettle, etc through immersing, crushing, mixing and sterilizing.
Description
Technical field
The present invention relates to a kind of drug world for the treatment of disease, particularly relate to a kind of medicine and manufacture method thereof for the treatment of hepatic disease.
Background technology
Liver is the internal organs that body weight for humans is wanted, liver has multiple functions such as storage, hemopoietic and blood coagulation, the adjusting blood circulation amount of metabolism, detoxifcation, the bile excretion of materials such as fat, various nutrient substance, in case liver generation disease, for example, diseases such as fatty liver, hepatitis, liver cirrhosis, hepatic ascites, hepatocarcinoma will cause the change of above-mentioned functions or lowly, particularly function of detoxification is low, until its function of loss, make human life critically ill.As everyone knows, cause that the hepar damnification reason has multiple factor, for example human body suction medicine or poisonous substance causes poisoning, and Bad Eating Habit, smoking, excessive consumption of alcohol are not burdened with liver such as function of detoxification, last a very long time, cause hepatocyte to destroy or necrosis, make hepar damnification, produce hepatomegaly, fatty liver, hepatitis, liver cirrhosis, hepatic ascites, diseases such as hepatocarcinoma, cause the human body asthenia, tired weak, lower for the resistance, influence health greatly, cause life critical, until death.
Liver cirrhosis, hepatic ascites are the progressive formations that the human liver accumulates over a long period until hepatocarcinoma, it is a kind of intractable internal disease, commonplace, it is wide to distribute, on the rise in recent years, according to the incomplete statistics of the relevant health organ in the world, at present the annual nearly up to ten million people in the whole world suffer from and state disease, and wherein half people death is that generally acknowledge both at home and abroad a kind of coagulates difficult pertinacious disease, become one of maximum obstinate disease of threat to life in the world today, cause very big threat to the mankind.Though at present multiple medicine is arranged, can not reach people and envision curative effect, particularly hepatocarcinoma generally adopts the chemotherapeutic treatment method, and it is weak curative effect not only, and nauseating in addition, diet goes down untoward reaction and side effect shortcomings such as alopecia.
Summary of the invention
The objective of the invention is to overcome above-mentioned prior art exists not enough, providing a kind of is raw material with " poisonous insect " all through the meticulous for many years developmental research of inventor several generations and a kind of of long-term clinical practice exploitation, treating the poisonous disease with poisonous drugs, the medicine and the manufacture method thereof of instant effect, curative effect height, the treatment hepatic disease that has no side effect.
A kind of medicine for the treatment of hepatic disease provided by the invention, by following raw materials in weight portion (medicine), through soaking roasting or drying, directly pulverize, be mixed, sterilize and make:
Cordyceps 3-15
Scolopendra or Scorpio 10-20
Aspongopus 8-40
Hirudo 11-50
Agkistrodon or Zaocys 15-30
Cantharis or Bufo siccus 3-10
Eupolyphaga Seu Steleophaga 3-30
Pheretima 4-13
Bombyx Batryticatus 3-15.
The medicine of treatment hepatic disease provided by the invention, described raw materials in weight portion is preferably:
Cordyceps 5-12
Scolopendra or Scorpio 10-15
Aspongopus 8-30
Hirudo 15-30
Agkistrodon or Zaocys 15-25
Cantharis or Bufo siccus 5-10
Eupolyphaga Seu Steleophaga 5-25
Pheretima 5-10
Bombyx Batryticatus 5-12.
The medicine of treatment hepatic disease provided by the invention, described raw materials in weight portion be more preferably:
Cordyceps 5-10
Scolopendra or Scorpio 12-15
Aspongopus 10-20
Hirudo 15-20
Agkistrodon or Zaocys 20-25
Cantharis or Bufo siccus 7-10
Eupolyphaga Seu Steleophaga 10-20
Pheretima 7-8
Bombyx Batryticatus 8-10.
In the medicine according to treatment hepatic disease provided by the invention, described hepatic disease is meant hepatitis, fatty liver, hepatomegaly, alcoholic liver, liver cirrhosis, hepatic ascites and hepatocarcinoma etc., particularly liver cirrhosis or hepatocarcinoma.Described medicine is meant any type of medicine, for example powder, capsule, tablet etc.Described raw material is each component raw material (or claiming crude drug), wherein:
Scolopendra: acrid in the mouth, warm in nature, the Serpentis a poisonous snake mentioned in ancient books is vicious, and is poisonous, and relieving convulsion relieving convulsion is arranged, and separates sore, the malignant boil toxic swelling that disappears, the antispasmodic effect of exorcising.
Scorpio: acrid in the mouth, property is flat, but wind-phlegm poison, a mouthful eye whirlpool is write, and acute infantile convulsion is sent out and is jerked.Property is put down, and is poisonous, dispels wind-phlegm, the effect that spasmolytic is twitched.
Bombyx Batryticatus: salty in the mouth, all wind infantile convulsion, the damp-phlegm sore throat, the sore cicatrix, property is flat, has except that wind heat, puts out liver-wind, ends and twitching, and reduce phlegm the disappear merit of sore of dehumidifying is handed over.
Agkistrodon or Zaocys, the temperature poison, all poison claim good, and sweet-salty is warm in nature, has except that rheumatism, and arresting convulsion ends the effect of twitching.
Eupolyphaga Seu Steleophaga: salty-cold, clots absorbing stimulates the menstrual flow, the removing blood stasis with potent drugs abdominal mass that disappears, salty in the mouth, reunion of bone, cold in nature, poisonous, salty go into blood can softening the hard mass, blood circulation promoting competent silt is arranged, dredge the meridian passage, the removing blood stasis with potent drugs abdominal mass is gathered caked flaccidity abdominal mass in the abdomen, resolving the hard mass is changed the congestion effect.
Pheretima: gas is cold, typhoid fever temperature bitterly, salty in the mouth, cold in nature, clearing away heat and alleviating pain is arranged, endogenous wind stopping, calm the frightened, dispel the wind, the meridian dredging, diuresis, the effect of supporing yang Pingyin.
Cantharis: very toxic, removing blood stasis stimulates the menstrual flow, main skin ulcer scrofula, and water channel can be manageed it, acrid in the mouth, cold in nature, blood stasis gathers in the abdomen that can disappear, and uses its treating the poisonous disease with poisonous drugs, treats various scabs and scrofula, hepatic ascites, liver cirrhosis, and cancer all have special effect to diseases such as female mammary gland uterus lump disease tumors especially.
Cordyceps: natural and artificial Cordyceps is arranged, be preferably natural cordyceps, sweet in the mouth, warm in nature, invigorating the lung and the kidney is arranged, flat kidney-replenishing kidney yin and be partial to supporing yang function is used for tonification unit to set upright.
Aspongopus: warm in nature, cold syndrome of the stomach benefit usefulness, supporing yang warming middle-JIAO, regulating QI to relieve pain has the warming the spleen stomach, helps the effect of kidney yang, is used for deficiency of spleen-YANG and kidneyYANG, the breast gastral cavity distending pain of the cold syndrome of the stomach stagnation of QI.
Hirudo: salty in the mouth, remove long-pending stasis of blood heavily fortified point, the product of falling that stimulates the menstrual flow, folding are hindered and can be fullyed recover from an illness, and property is flat, and is poisonous, removing blood stasis arranged, the effect of stimulating the menstrual flow and closing.Be used for blood stasis and gather, in bulk in the abdomen.
Bufo siccus: the gas cold, kill infantile malnutrition erosion abdominal mass, pestilence energy Pi, sore can be dispelled.Poisonous, there is passive parasite killing Herba Sidae Szechuensis swollen, the effect that pain relieving is had one's ideas straightened out.Can eliminate the malignant boil toxic swelling, warding off bursts dislikes the epidemic disease poison.
The comprehensive compatibility of above-mentioned raw materials medicine, coordinated has strong malicious counteracting toxic substances, strengthens blood stasis, and the reinforcing and reducing combination removes heresy and sets upright, and consolidates; Put out liver-wind, remove wind heat, damp-phlegm eliminating; Shujin helps bone, dredge the meridian passage, and broken little abdominal mass is gathered middle in bulk, tonneau defecation; Removing food stagnancy merit heavily fortified point, remove to dislike tissue regeneration promoting, Yin Yang balancing, inrigorating qi and promoting blood circulation improves the immunity of human body, improves microcirculation in human body, strengthens the metabolic function of human body; Thereby improve the effective percentage and the cure rate of treatment hepatic disease, be difficult to capture hepatic disease such as liver cirrhosis, hepatocarcinoma for current people especially, nephropathy etc. have very high curative effect.
The manufacture method of the medicine of treatment hepatic disease provided by the invention comprises the following steps:
1. Cordyceps (natural or artificial Cordyceps) was soaked 24-48 hour with yellow wine or ethanol (ethanol) or Chinese liquor etc.Soak yellow wine, Chinese liquor or ethanol consumption (in right amount) and do not limit, need only submergence Cordyceps just can, bake or be dried into meticulous powder then.
2. with selected cantharis or Bufo siccus, Agkistrodon or Zaocys, Aspongopus, Scolopendra or Scorpio, Pheretima, Eupolyphaga Seu Steleophaga, Hirudo, Bombyx Batryticatus is dried by the fire (roasting) dry powder respectively and is broken into meticulous powder or Subnano-class or nanoscale impalpable powder, be preferably nanoscale, being beneficial to human body absorbs fully, improve pharmacodynamic feature, improve effective percentage and cure rate greatly, wherein drying drying as black watt of the available Chinese medicine circle employing of pulverizing dries, mechanical drying and artificial or mechanical activation comminution technology, grind or pulverizer as disc sharpener or base, the commercially available modern any grinder of preferred employing, pulverizer or wave pulverizer, more preferably adopt commercially available wave pulverizer, be ground into Subnano-class or nanoscale impalpable powder.
3. with step 1. and the powder that 2. obtains (meticulous powder and/or impalpable powder) under aseptic condition by the abundant mix homogeneously of described weight proportion, become capsule (as 0.25 to 0.5 gram) through sterilization treatment, molding as being pressed into tablet or fill then.
The manufacture method of the medicine of treatment hepatic disease provided by the invention also can adopt and will bake or dry, be ground into meticulous powder or nanoscale impalpable powder respectively by described weight portion proportioning, carry out mix homogeneously then, sterilization, fill or tabletting finished product medicament under aseptic condition.
The medicament characteristics of treatment hepatic disease provided by the invention are raw material for 1. all adopting " poisonous insect ", and the treating the poisonous disease with poisonous drugs novel method of treatment has no side effect.2. regulate people's function, Yin Yang balancing, inrigorating qi and promoting blood circulation improves body immunity, improves people's microcirculation, strengthens the metabolic function of human body.3. adopt Subnano-class or nanoscale impalpable powder, be very advantageous in people and absorb, shorten the course of treatment (it is strange fast to take effect), improve effective percentage and cure rate greatly, the curative effect height is the good medicine of a new generation's treatment hepatic disease.
The medicament of treatment hepatic disease provided by the invention or treatment liver various diseases, for example hepatic disease such as hepatitis, fatty liver, alcoholic liver, hepatomegaly, hepatic ascites, hepatocarcinoma; This medicine also can be treated diabetes, cardiovascular and cerebrovascular disease, and zang-fu diseases curative effects such as rheumatism are fine.
The specific embodiment
The present invention further specifies the present invention with the following example, but protection scope of the present invention is not limited to the following example.
Embodiment 1
Cordyceps (natural) was soaked in an amount of yellow wine one day by the weight of example in the table 11, dries then and grind to form meticulous powder.Selected oven dry is ground into the Subnano-class impalpable powder with commercially available wave pulverizer respectively by Scolopendra, Aspongopus, Hirudo, Agkistrodon, cantharis, Eupolyphaga Seu Steleophaga, Pheretima, the Bombyx Batryticatus of table 1 weight, mix homogeneously in blender then, sterilization is irritated into 0.5 gram capsule and is got the medicament capsule that the present invention treats hepatic disease under aseptic condition again.
Table 1
| Manually | 5 | 6 | 7 | 15 | 15 | ||||
| Scolopendra | 10 | 12 | 15 | 20 | 10 | ||||
| Scorpio | 10 | 13 | 20 | ||||||
| Aspongopus | 8 | 10 | 15 | 20 | 20 | 30 | 30 | 10 | |
| Hirudo | 11 | 15 | 15 | 25 | 20 | 40 | 40 | 10 | |
| Agkistrodon | 15 | 20 | 20 | 25 | 25 | ||||
| Zaocys | 16 | 25 | 10 | ||||||
| Cantharis | 5 | 7 | 8 | 8 | 10 | ||||
| Bufo siccus | 7 | 10 | 10 | ||||||
| Eupolyphaga Seu Steleophaga | 3 | 3 | 10 | 20 | 20 | 25 | 30 | 10 | |
| Pheretima | 4 | 4 | 7 | 8 | 10 | 13 | 13 | ||
| Bombyx Batryticatus | 3 | 3 | 8 | 13 | 10 | 15 | 13 | 15 | |
| Yellow wine | In right amount | In right amount | In right amount | In right amount | In right amount | ||||
| Ethanol | In right amount | ||||||||
| Chinese liquor | In right amount | ||||||||
Embodiment 2-5,7-8
Embodiment 2-5, the step of 7-8 is identical with embodiment 1, and different is to be undertaken by listed raw material and weight in the table 1.
Embodiment 6, and each crude drug is ground into the nanoscale impalpable powder with commercially available wave pulverizer respectively by table 1 example 6 weight, mix homogeneously then, and sterilization, fill become 0.5 gram capsule.
The present invention further specifies to take with following case and the invention provides medicament part clinical effectiveness.
Case 1
Open and build, the man, 42 years old, suffer from liver cirrhosis, splenectomy, people Hei Of-thin does not become sample, anorexia, and also it is bad to sleep, constipation.Treat the hepatic disease medicament since having obeyed the present invention, after 10 days, diarrhoea, antiperspirant will rise 5.6 one night, has loose bowels again, perspire again, m seq, a feel brisk condition of mind has hunger sensation, and a feel appetite is opened, and after the week, stool recovers normally.After March, go to hospital to do inspection, liver cirrhosis does not a bit have (antiinflammatory).He people who why life has not been entertained hope that oneself is taken aback has fully recovered unexpectedly.
Case 2
Draw, the man, 56 years old, liver friend fibroma, it is invalid to seek medical advice everywhere, and clothes the present invention treats hepatic disease medicament March, recovery from illness.
Case 3
He Ying, the woman, 50 years old, later period of hepatocarcinoma, chemotherapy once, abdominal distention can not be taken food, do not defecate, the stool also be lump.Must separate just with medicine.Control oneself and defecate since clothes the present invention treats liver medicament one Zhou Houneng, not medication has solved, 2 week the back stool have several days and once become 2.3 days once, begin to have loose bowels after one month, abdominal distention alleviates, the people also begins to eat of soft diet and some fruit.It is many to go examination in hospital to find that cancerous cell reduces after half a year.After August, it is normal that the people has recovered.
Case 4
Liu Jun, man, 39 years old, liver cirrhosis, fatty liver, abdominal distention, umbilicus inflammation water outlet.Anorexia.Clothes the present invention treats behind the liver medicament and to be almost recovered in 2 months.Normally working.
Case 5
Ji Guiqin, the woman, 62 years old, diabetes 2 types, 10 years, beat insulin, 2 times on the one, each 28 milligrams, clothes the present invention treats the liver medicament and sooner or later respectively subtracts 10 milligrams after one month, and insulin reduces to each 5 milligrams sooner or later after February, all removes insulin after March.Consolidated in four month.Spring eat the autumn eat over one month perfect.Autumn eats the spring and reinforces taking over one month.There have been several patients to obtain recovery from illness.Thoroughly break away from the lifelong tenure mistaken ideas of diabetes.
Case 6
Liu increases, man, 60 years old.The diabetes more than ten years.Obey various Western medicine such as Jiangtangwan pill, still blood glucose is taken the present invention and is treated all withdrawals after 3 months of hepatic disease medicament more than 20 always.Do not obey any Western medicine in 3 years again.
Case 7
Yang Guihua, woman, 40 years old, 3 of hysteromyoma.Hospital allows her perform an operation, and she be unwilling to, comes here, and clothes the present invention treats liver medicament January, and menstruation is a lot of, and dose strengthens, and this month is still like this, and one of clot and menstruation are flowed out together, the 3rd month, replenish cleaning.Go examination in hospital disease tumor not have, recovery from illness.
Case 8
Lu Shuying, the woman.37 years old, metrocystosis, clothes the present invention treats the hepatic disease medicament and gets rid of recovery from illness February.
Case 9
Wu Shuqing, the woman, 72 years old, heart disease, hypertension, clothes the present invention treats the hypertension pill that the hepatic disease medicament taking March always and has not thoroughly eaten, 3 years any medicines of reuse not.
Case 10
Xie Sheng, the man, 56 years old, be cancer late period, clothes the present invention treats the hepatic disease medicament and connects drawstring after 15 days and tell, and cancerous cell reduces after March.Recovery from illness half a year.
Through clinical trial for many years, this medicine is to hepatic disease, nephropathy, and diabetes, cardiovascular disease all have better curative effect.As pointing out in the theory of Chinese medical science: with malicious merit poison, the emphasis detoxicating, comprehensively regulating improves the microcirculation of human body, just can guarantee that human body has living of quality.
Claims (5)
1, a kind of medicine for the treatment of hepatic disease, by following raw materials in weight portion, through soaking, bake or drying, directly pulverize, be mixed, sterilize and make:
Cordyceps 3-15
Scolopendra or Scorpio 10-20
Aspongopus 8-40
Hirudo 11-50
Agkistrodon or Zaocys 15-30
Cantharis or Bufo siccus 3-10
Eupolyphaga Seu Steleophaga 3-30
Pheretima 4-13
Bombyx Batryticatus 3-15.
2, according to the medicine of the treatment hepatic disease of claim 1, it is characterized in that described raw materials in weight portion is:
Cordyceps 5-12
Scolopendra or Scorpio 10-15
Aspongopus 8-30
Hirudo 15-30
Agkistrodon or Zaocys 15-25
Cantharis or Bufo siccus 5-10
Eupolyphaga Seu Steleophaga 5-25
Pheretima 5-10
Bombyx Batryticatus 5-12.
3, according to the medicine of the treatment hepatic disease of claim 2, it is characterized in that described raw materials in weight portion is:
Cordyceps 5-10
Scolopendra or Scorpio 12-15
Aspongopus 10-20
Hirudo 15-20
Agkistrodon or Zaocys 20-25
Cantharis or Bufo siccus 7-10
Eupolyphaga Seu Steleophaga 10-20
Pheretima 7-8
Bombyx Batryticatus 8-10.
4, the manufacture method of the medicine of the arbitrary treatment hepatic disease of a kind of claim 1-3 comprises the following steps:
1. with Cordyceps by described weight portion proportioning, with yellow wine or Chinese liquor or soak with ethanol 24 to 48 hours, bake or be dried into meticulous powder then;
2. with selected cantharis or Bufo siccus, Agkistrodon or Zaocys, Aspongopus, Scolopendra or Scorpio, Pheretima, Eupolyphaga Seu Steleophaga, Hirudo, Bombyx Batryticatus by described weight portion proportioning, be ground into meticulous powder or Subnano-class or nanoscale impalpable powder respectively;
3. 1. and the powder that 2. obtains abundant mix homogeneously under aseptic condition, must treat the medicament of hepatic disease through sterilization treatment, molding with step.
5, the manufacture method of the medicine of the arbitrary treatment hepatic disease of a kind of claim 1-3 comprises the following steps:
1. selected Cordyceps, cantharis or Bufo siccus, Agkistrodon or Zaocys, Aspongopus, Scolopendra or Scorpio, Pheretima, Eupolyphaga Seu Steleophaga, Hirudo, Bombyx Batryticatus are pressed described weight portion proportioning, be ground into meticulous powder or Subnano-class or nanoscale impalpable powder respectively;
2. the powder that 1. step is obtained abundant mix homogeneously under aseptic condition must be treated the medicament of hepatic disease through sterilization treatment, molding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100766069A CN100411634C (en) | 2006-04-19 | 2006-04-19 | Medication for treating liver disease, and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100766069A CN100411634C (en) | 2006-04-19 | 2006-04-19 | Medication for treating liver disease, and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1872096A true CN1872096A (en) | 2006-12-06 |
| CN100411634C CN100411634C (en) | 2008-08-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100766069A Expired - Fee Related CN100411634C (en) | 2006-04-19 | 2006-04-19 | Medication for treating liver disease, and preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177760A (en) * | 2016-07-30 | 2016-12-07 | 陈国礼 | A kind of medicine treating hepatomegaly and preparation method |
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2006
- 2006-04-19 CN CNB2006100766069A patent/CN100411634C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177760A (en) * | 2016-07-30 | 2016-12-07 | 陈国礼 | A kind of medicine treating hepatomegaly and preparation method |
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| CN100411634C (en) | 2008-08-20 |
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