CN1830482A - Chinese medicinal composition and application for treating child pneumonia for treating - Google Patents
Chinese medicinal composition and application for treating child pneumonia for treating Download PDFInfo
- Publication number
- CN1830482A CN1830482A CN 200510061798 CN200510061798A CN1830482A CN 1830482 A CN1830482 A CN 1830482A CN 200510061798 CN200510061798 CN 200510061798 CN 200510061798 A CN200510061798 A CN 200510061798A CN 1830482 A CN1830482 A CN 1830482A
- Authority
- CN
- China
- Prior art keywords
- parts
- rhizoma
- tablet
- flos lonicerae
- herba houttuyniae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010035664 Pneumonia Diseases 0.000 title claims abstract description 18
- 239000000203 mixture Substances 0.000 title claims description 16
- 239000003814 drug Substances 0.000 claims abstract description 47
- 239000000463 material Substances 0.000 claims abstract description 9
- 241000605447 Anemarrhena Species 0.000 claims abstract description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 37
- 239000000284 extract Substances 0.000 claims description 21
- 241000628997 Flos Species 0.000 claims description 19
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000000654 additive Substances 0.000 claims description 13
- 239000002775 capsule Substances 0.000 claims description 13
- 238000002360 preparation method Methods 0.000 claims description 12
- 239000003826 tablet Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 10
- 239000008187 granular material Substances 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 239000002552 dosage form Substances 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- 238000005303 weighing Methods 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 4
- 238000010992 reflux Methods 0.000 claims description 4
- 239000008107 starch Substances 0.000 claims description 4
- 235000019698 starch Nutrition 0.000 claims description 4
- 239000006188 syrup Substances 0.000 claims description 4
- 235000020357 syrup Nutrition 0.000 claims description 4
- 238000002481 ethanol extraction Methods 0.000 claims description 3
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims description 3
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims description 3
- GYCKQBWUSACYIF-UHFFFAOYSA-N o-hydroxybenzoic acid ethyl ester Natural products CCOC(=O)C1=CC=CC=C1O GYCKQBWUSACYIF-UHFFFAOYSA-N 0.000 claims description 3
- ARIWANIATODDMH-AWEZNQCLSA-N 1-lauroyl-sn-glycerol Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)CO ARIWANIATODDMH-AWEZNQCLSA-N 0.000 claims description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 2
- 229920001353 Dextrin Polymers 0.000 claims description 2
- 239000004375 Dextrin Substances 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- ARIWANIATODDMH-UHFFFAOYSA-N Lauric acid monoglyceride Natural products CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 2
- 239000004141 Sodium laurylsulphate Substances 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 235000019425 dextrin Nutrition 0.000 claims description 2
- 239000007919 dispersible tablet Substances 0.000 claims description 2
- 239000007938 effervescent tablet Substances 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 235000011187 glycerol Nutrition 0.000 claims description 2
- 239000000787 lecithin Substances 0.000 claims description 2
- 235000010445 lecithin Nutrition 0.000 claims description 2
- 229940067606 lecithin Drugs 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 2
- 238000005457 optimization Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 235000014101 wine Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 3
- 240000002234 Allium sativum Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241001038563 Pseudostellaria Species 0.000 abstract 1
- 244000223014 Syzygium aromaticum Species 0.000 abstract 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 abstract 1
- 229930191283 anemarrhena Natural products 0.000 abstract 1
- 235000004611 garlic Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 15
- 230000000694 effects Effects 0.000 description 7
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 230000001681 protective effect Effects 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 241000699670 Mus sp. Species 0.000 description 4
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 241000699666 Mus <mouse, genus> Species 0.000 description 3
- 229940100050 virazole Drugs 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241000193998 Streptococcus pneumoniae Species 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000010255 intramuscular injection Methods 0.000 description 2
- 239000007927 intramuscular injection Substances 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 2
- 241000712461 unidentified influenza virus Species 0.000 description 2
- 206010011469 Crying Diseases 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010035737 Pneumonia viral Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010039740 Screaming Diseases 0.000 description 1
- 241000238370 Sepia Species 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 235000019636 bitter flavor Nutrition 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000012869 ethanol precipitation Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000003519 ventilatory effect Effects 0.000 description 1
- 208000009421 viral pneumonia Diseases 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Group life rate | Dosage mg/kg | Mortality rate (%) | Dead protective rate (%) | Average life day (d) | Prolong and give birth to (%) |
Matched group model group virazole group low dosage of the present invention high dose of the present invention | - - 20 20 40 | - 100 40 30 10 | - - 60 70 90 | 15 6.5±3.9 10.2±3.9 * 11.5±3.8 * 13.3±4.5 * | 88.9 76.7 106.5 |
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2005100617981A CN1830482B (en) | 2005-12-05 | 2005-12-05 | Chinese medicinal composition and application for treating child pneumonia for treating |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2005100617981A CN1830482B (en) | 2005-12-05 | 2005-12-05 | Chinese medicinal composition and application for treating child pneumonia for treating |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1830482A true CN1830482A (en) | 2006-09-13 |
CN1830482B CN1830482B (en) | 2011-11-09 |
Family
ID=36993082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005100617981A Expired - Fee Related CN1830482B (en) | 2005-12-05 | 2005-12-05 | Chinese medicinal composition and application for treating child pneumonia for treating |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1830482B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102499977A (en) * | 2011-11-28 | 2012-06-20 | 马英 | Traditional Chinese medicine preparation for treating children bronchopneumonia |
CN102613390A (en) * | 2012-03-26 | 2012-08-01 | 张奎昌 | Garlic straw extracts and preparation method and application thereof |
-
2005
- 2005-12-05 CN CN2005100617981A patent/CN1830482B/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102499977A (en) * | 2011-11-28 | 2012-06-20 | 马英 | Traditional Chinese medicine preparation for treating children bronchopneumonia |
CN102499977B (en) * | 2011-11-28 | 2013-07-17 | 薛洁 | Traditional Chinese medicine preparation for treating children bronchopneumonia |
CN102613390A (en) * | 2012-03-26 | 2012-08-01 | 张奎昌 | Garlic straw extracts and preparation method and application thereof |
CN102613390B (en) * | 2012-03-26 | 2013-08-14 | 张奎昌 | Garlic straw extracts and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
CN1830482B (en) | 2011-11-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN100344313C (en) | Chinese patent drug for treating infantile cold and repeated cold, and its prepn. method | |
WO2021208335A1 (en) | Traditional chinese medicine composition capable of removing toxins, dispelling dampness, and disinhibiting throat, and application thereof | |
CN105535439A (en) | Traditional Chinese medicinal composition for treating pharyngitis and preparation method thereof | |
CN104435294A (en) | Traditional Chinese medicine for treating respiratory viral infection and pharmaceutical application thereof | |
CN111249390A (en) | Forsythia-astragalus root compound preparation and preparation method and application thereof | |
CN101683420B (en) | Applications of traditional Chinese medicine composition in preparation of medicament for treating acute pharyngitis | |
WO2023125798A1 (en) | Traditional chinese medicine composition and preparation method and application thereof | |
CN1935194A (en) | Chinese medicine composition for treating nephroma | |
CN110193061B (en) | Preparation and application of traditional Chinese medicine granules for treating or preventing children influenza virus infection | |
CN1830482B (en) | Chinese medicinal composition and application for treating child pneumonia for treating | |
CN1814195B (en) | Chinese medicine composition for treating gynecopathy and its preparation method thereof | |
CN1814176B (en) | Chinese medicinal composition for treating tuberculosis and its preparation method | |
CN111358906B (en) | Traditional Chinese medicine composition suitable for exogenous diseases | |
CN1899499A (en) | Chinese medicine composition for treating cold and its preparing method and use | |
CN106075229A (en) | A kind of Chinese medicinal composition preparation treating anemopyretic cold | |
CN1899574A (en) | Chinese medicine composition for preventing and controlling liver cancer and its use | |
CN1814194A (en) | Chinese-western medicine composition for treating in fant's common cold and use thereof | |
CN1814250B (en) | Chinese medicine composition for treating liver cirrhosis ascites and preparation method thereof | |
CN1915401B (en) | Composition of Chinese traditional medicine for treating phthisis, and application | |
CN104524187B (en) | A kind of Chinese medicine preparation for the treatment of laryngopharynx swelling and pain and preparation method thereof | |
CN1291729C (en) | Antiviral Chinese medicine prepn of Hypericum perforatumand its prepn process | |
CN105412407A (en) | Traditional Chinese medicine composition for preventing and curing flu as well as preparation method and application thereof | |
CN101176765A (en) | Chinese medicine detoxication preparations and preparation method thereof | |
WO2024125422A1 (en) | Pharmaceutical composition for preventing and treating coronavirus infections, preparation method therefor and use thereof | |
CN101700323B (en) | Pharmaceutical composition for preventing and treating liver cancer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: NINGBO YUANZHI BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: YANG XIONGZHI Effective date: 20110927 Free format text: FORMER OWNER: YANG YIKAI |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20110927 Address after: 315100, room 10, building 68, Lane 402, Tai Mo Road, Ningbo, Zhejiang, Yinzhou District Applicant after: NINGBO YUANZHI BIOTECHNOLOGY Co.,Ltd. Address before: 315100 Zhejiang city of Ningbo province Yinzhou District County Road No. 888 east section of Zhejiang Pharmaceutical College Applicant before: Yang Xiongzhi Co-applicant before: Yang Yijie |
|
CI01 | Publication of corrected invention patent application |
Correction item: The patent holder; the address of the patent holder Correct: Ningbo Yuanzhi Biotechnology Co., Ltd.|315100, room 10, building 68, Lane 402, Tai Mo Road, Ningbo, Zhejiang, Yinzhou District False: Yang Xiongzhi Yang Yikai|315100 Zhejiang city of Ningbo province Yinzhou District County Road No. 888 east section of Zhejiang Pharmaceutical College Number: 45 Volume: 27 |
|
CI03 | Correction of invention patent |
Correction item: The patent holder; the address of the patent holder Correct: Ningbo Yuanzhi Biotechnology Co., Ltd.|315100, room 10, building 68, Lane 402, Tai Mo Road, Ningbo, Zhejiang, Yinzhou District False: Yang Xiongzhi Yang Yikai|315100 Zhejiang city of Ningbo province Yinzhou District County Road No. 888 east section of Zhejiang Pharmaceutical College Number: 45 Page: The title page Volume: 27 |
|
ERR | Gazette correction |
Free format text: CORRECT: PATENTEE PATENTEE ADDRESS; FROM: YANG XIONGZHI YANG YIKAI;315100 ZHEJIANG PHARMACEUTICAL COLLEGE, NO.888, EAST SECTION, YINXIAN AVENUE, YINZHOU DISTRICT, NINGBO CITY, ZHEJIANG PROVINCE TO: NINGBO YUANZHI BIOTECHNOLOGY CO., LTD.;315100 ROOM 402, BUILDING 10, LANE 68, TAIYU ROAD, YINZHOU DISTRICT, NINGBO CITY, ZHEJIANG PROVINCE |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111109 Termination date: 20131205 |