CN1820740A - Oral liquor for supplementing calcium and zinc and preparing method - Google Patents

Oral liquor for supplementing calcium and zinc and preparing method Download PDF

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Publication number
CN1820740A
CN1820740A CN 200510009748 CN200510009748A CN1820740A CN 1820740 A CN1820740 A CN 1820740A CN 200510009748 CN200510009748 CN 200510009748 CN 200510009748 A CN200510009748 A CN 200510009748A CN 1820740 A CN1820740 A CN 1820740A
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CN
China
Prior art keywords
calcium
zinc
lactate
water
gluconate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 200510009748
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Chinese (zh)
Inventor
卢传友
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmaceutical Factory No6 Harbin Pharmaceutical Group
Original Assignee
Pharmaceutical Factory No6 Harbin Pharmaceutical Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaceutical Factory No6 Harbin Pharmaceutical Group filed Critical Pharmaceutical Factory No6 Harbin Pharmaceutical Group
Priority to CN 200510009748 priority Critical patent/CN1820740A/en
Publication of CN1820740A publication Critical patent/CN1820740A/en
Pending legal-status Critical Current

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Abstract

The present invention relates to oral liquor for supplementing calcium and zinc and its preparation, and the oral liquor for supplementing calcium and zinc as essential nutrients for human body, especially infant, teenage, pregnant woman, woman in lactation period, etc. The oral liquor for supplementing calcium and zinc consists of calcium gluconate 40-60 weight portions, calcium lactate 25-30 weight portions, zinc lactate 0.5-3 weight portions and water 1000 weight portions.

Description

Replenish the oral liquid and the manufacture method of calcium zinc
Technical field:
The present invention relates to a kind of health beverage, the specific aim health product of particularly a kind of additional calcium and zinc.
Background technology:
Calcium and zinc are the nutrients of needed by human, especially to growth promoter crowds such as infant, child, teenager and anemia of pregnant woman, the contour demand crowd of wet nurse, special important meaning is arranged, because newborn class is on the low side in the dietary structure of China, the intake of calcium and zinc is lower than requirement, often have again in the diet processes and disturb the factor that absorbs to take place, calcium deficiency zinc deficiency problem is more serious among the above crowd.
Problem at Chinese zinc deficiency and calcium deficiency, people did multiple trial for many years, in the Chinese patent publication number 1075080 a kind of Zn-Ca oral liquid is disclosed for example, wherein calcium and zinc all adopt the glucose acid group, in order to guarantee to contain the stability of formulation of glucose acid group, have to add the common compatibility of sodium citrate, nipalgin and simple syrup, these compositions and Zinc and calcium supplement are irrelevant, may produce harmful effect to human body by accumulation after entering human body.
Summary of the invention: the purpose of this invention is to provide a kind of calcium and zinc of effectively replenishing, avoid other element to enter intravital new type of health functional oral liquid simultaneously, the present invention also provides the manufacture method of this oral liquid.
Above-mentioned purpose realizes by following technical scheme:
Replenish the oral liquid of calcium zinc, be made up of calcium gluconate, calcium lactate, zinc lactate and water, the ratio of weight and number of described calcium gluconate, calcium lactate, zinc lactate and water is: calcium gluconate 40-60, calcium lactate 25-30, zinc lactate 0.5-3, water 1000.
The oral liquid of above-mentioned additional calcium zinc, described ratio of weight and number is: calcium gluconate 42, calcium lactate 26, zinc lactate 2, water 1000.
A kind of manufacture method of oral liquid of additional calcium zinc comprises:
A. getting ratio of weight and number is calcium gluconate 40-60, calcium lactate 25-30, zinc lactate 0.5-3, joins in 1000 parts of water;
B. be heated to more than 60 ℃, stir and make it dissolving;
C. dissolve post-heating to boiling, keep boiling 20 minutes;
D. the fill of lowering the temperature, sterilization.
This technical scheme has following beneficial effect:
1. product reasonable mixture ratio of the present invention.Therefore child's hyperhidrosis situation of calcium deficiency is more serious, thus intravital zinc is taken out of, from the science angle, replenishes the calcium and zinc supplement has necessary relation.But because China replenishes the calcium separately and the medicine and the health product of independent zinc supplement are many, the head of a family usually thinks that child's calcium deficiency or zinc deficiency are very serious under the public opinion propaganda, most of heads of a family also are difficult to control reasonable volume, cause China recent years child's calcium intoxication and zinc poisoning sickness rate to rise significantly thus.The invention provides rational calcium zinc ratio, can effectively control the out of proportion of calcium zinc, avoid single heavy dose of adverse consequences of bringing of using.
2. product of the present invention adopts compound Lactated form administration, good antimicrobial effect, by its synergism, make product good absorbing of the present invention, through Clinical Laboratory, taking this product compares with the contrast groups of taking separately with three kinds of single products of dosage, after the course of treatment, the absorbance of calcium and zinc is higher than contrast groups more than 20%, and has obviously increased zinc and the calcium concentration in the blood, obviously bone density improving, reduce skeleton fragility, make skeleton obtain rapidly effectively calcification,, improved the symptom of zinc deficiency simultaneously for bone metabolism and bone growth promoting nourishing bone provide best raw material, the facilitating digestion function, nootropics improves immunity, thereby has strengthened body constitution.
3. the medicinal adjuvant addition of national Specification; be to suffer from a certain disease suddenly according to human body; the limit value of medication; and a kind of heavy dose, long-term non-disease conditions the often non-treatment articles that is similar to food of oral liquid for health care; even the use amount of adjuvant wherein is no more than standard, also usually can form heavy dose of accumulation in vivo.Do not contain the adjuvant that tradition is replenished the calcium and must be added in the product of the present invention, reduced harmful substances such as antiseptic and infiltrated to the pressure of human body, avoided the accumulation of harmful substance, it is unbalance to have avoided the isometric phase of salt acid group to take in the cylinder electrolyte that brings.
4. product of the present invention confirms in the mouth acute toxicity test that white mice carries out on one's body, this product belongs to the avirulence material, through Salmonella reversion test, PCEMNR micronucleus test and mouse sperm deformity test detect all negative, three genetic toxicity test testing results are all negative, through 30 days feeding trials, do not see that it has any toxicity damage effect to animal.After this, again through 300 routine Clinical Laboratorys, take this product after, total effective rate is 90.67%, this product has the zinc supplement of replenishing the calcium definite effect, take Fang Bin, characteristics such as have no side effect.
5. simple, advanced, the operation easily of method technology of the present invention.
The specific embodiment of the present invention:
Embodiment 1:
Replenish the oral liquid of calcium zinc, form by calcium gluconate, calcium lactate, zinc lactate and water.
Get in the pure water that 1 kilogram of 40 kilograms of described calcium gluconate, 26 kilograms of calcium lactate, zinc lactate joins 1050 kilograms.Open more than the Steam Heating to 60 ℃, start stirring, make above each substance dissolves; Continue to be heated to boiling after the dissolving, keep boiling 20 minutes; Steam off heating, logical water quench cooling after quality inspection is qualified, adds pure water to 1000 liter, fill, sterilization.10 milliliters every bottle of this products, oral each two, every day twice, every month course of treatment.
Embodiment 2:
Replenish the oral liquid of calcium zinc, form by calcium gluconate, calcium lactate, zinc lactate and water.
Pure water is joined in the stirred tank, open more than the Steam Heating to 60 ℃, get in the pure water that 1.5 kilograms of 43 kilograms of described calcium gluconate, 27 kilograms of calcium lactate, zinc lactate join 1050 kilograms.Start stirring, make above each substance dissolves; Continue to be heated to boiling after the dissolving, keep boiling 20 minutes; Steam off heating, logical water quench cooling after quality inspection is qualified, adds pure water to 1000 liter, fill, sterilization.10 milliliters every bottle of this products, oral each two, every day twice, every month course of treatment.
Embodiment 3:
Replenish the oral liquid of calcium zinc, form, be high zinc prescription by calcium gluconate, calcium lactate, zinc lactate and water.
Pure water is joined in the stirred tank, open more than the Steam Heating to 70 ℃, get in the pure water that 3 kilograms of 45 kilograms of described calcium gluconate, 30 kilograms of calcium lactate, zinc lactate join 1050 kilograms.Start stirring, make above each substance dissolves; Continue to be heated to boiling after the dissolving, keep boiling 20 minutes; Steam off heating, logical water quench cooling after quality inspection is qualified, adds pure water to 1000 liter, fill, sterilization.10 milliliters every bottle of this products, oral each two, every day twice, every month course of treatment.
Embodiment 4:
Replenish the oral liquid of calcium zinc, form, be low zinc prescription by calcium gluconate, calcium lactate, zinc lactate and water.
Pure water is joined in the stirred tank, open more than the Steam Heating to 70 ℃, get in the pure water that 0.5 kilogram of 60 kilograms of described calcium gluconate, 25 kilograms of calcium lactate, zinc lactate joins 1050 kilograms.Start stirring, make above each substance dissolves; Continue to be heated to boiling after the dissolving, keep boiling 20 minutes; Steam off heating, logical water quench cooling after quality inspection is qualified, adds pure water to 1000 liter, fill, sterilization.10 milliliters every bottle of this products, oral each two, every day twice, every month course of treatment.

Claims (3)

1. the oral liquid of an additional calcium zinc, be made up of calcium gluconate, calcium lactate, zinc lactate and water, it is characterized in that: the ratio of weight and number of described calcium gluconate, calcium lactate, zinc lactate and water is: calcium gluconate 40-60, calcium lactate 25-30, zinc lactate 0.5-3, water 1000.
2. the oral liquid of additional calcium zinc according to claim 1 is characterized in that: described ratio of weight and number is: calcium gluconate 42, calcium lactate 26, zinc lactate 2, water 1000.
3. the manufacture method of the oral liquid of an additional calcium zinc is characterized in that:
A. getting ratio of weight and number is calcium gluconate 40-60, calcium lactate 25-30, zinc lactate 0.5-3, joins in 1000 parts the water;
B. be heated to more than 60 ℃, stir and make it dissolving;
C. dissolve post-heating to boiling, keep boiling 20 minutes;
D. the fill of lowering the temperature, sterilization.
CN 200510009748 2005-02-17 2005-02-17 Oral liquor for supplementing calcium and zinc and preparing method Pending CN1820740A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200510009748 CN1820740A (en) 2005-02-17 2005-02-17 Oral liquor for supplementing calcium and zinc and preparing method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200510009748 CN1820740A (en) 2005-02-17 2005-02-17 Oral liquor for supplementing calcium and zinc and preparing method

Publications (1)

Publication Number Publication Date
CN1820740A true CN1820740A (en) 2006-08-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200510009748 Pending CN1820740A (en) 2005-02-17 2005-02-17 Oral liquor for supplementing calcium and zinc and preparing method

Country Status (1)

Country Link
CN (1) CN1820740A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273704A (en) * 2011-06-16 2011-12-14 牟一心 Calcium-zinc honeysuckle flower leaf beverage and preparation method thereof
CN102960566A (en) * 2012-12-06 2013-03-13 乌鲁木齐市金蟾兽药有限公司 Special liquid feed additive for small rumination animal as well as preparation method and applications thereof
CN110882271A (en) * 2018-09-10 2020-03-17 刘力 Novel double-calcium pharmaceutical composition

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273704A (en) * 2011-06-16 2011-12-14 牟一心 Calcium-zinc honeysuckle flower leaf beverage and preparation method thereof
CN102960566A (en) * 2012-12-06 2013-03-13 乌鲁木齐市金蟾兽药有限公司 Special liquid feed additive for small rumination animal as well as preparation method and applications thereof
CN110882271A (en) * 2018-09-10 2020-03-17 刘力 Novel double-calcium pharmaceutical composition

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