CN1813925A - Chinese medicine formulation for treating pharynx and larynx disease and its preparing method - Google Patents
Chinese medicine formulation for treating pharynx and larynx disease and its preparing method Download PDFInfo
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- CN1813925A CN1813925A CN 200510130514 CN200510130514A CN1813925A CN 1813925 A CN1813925 A CN 1813925A CN 200510130514 CN200510130514 CN 200510130514 CN 200510130514 A CN200510130514 A CN 200510130514A CN 1813925 A CN1813925 A CN 1813925A
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Abstract
The present invention discloses a Chinese medicine preparation for curing diseases of throat. It is made up by using (by weight portion) 5-10 portions of native achyranthes root, 3-6 portions of kalimeris indica, 1-4 portions of plantago and 1 portion of carpesium through a certain preparation process. Said preparation process includes the steps of mixing raw materials, pulverizing, decocting, separating, extracting liquid medicine, reducing pressure and concentrating, etc.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of laryngopharyngeal diseases and preparation method thereof.
Background technology
Pharyngolaryngitis is a kind of very upper respiratory tract infection disease of seeing more, often cause by Common Cold, almost everyone all had in life should disease experience, only somebody's patient's condition lightly, the somebody is heavy, the somebody is easy, the somebody seldom gets.
The laryngopharyngeal diseases common sympton comprises hoarseness and has sore throat.
The hoarseness commonly encountered diseases is because of there being polyp of vocal cord, vocal nodule, chronic laryngitis, acute laryngitis, the innocent and malignant tumour of larynx, vocal cords cyst, vocal cord paralysis, the gastric acid pharyngitis etc. that backflows.
1, polyp of vocal cord, vocal nodule, chronic laryngitis: the patient has excessive pronunciation more, as long-time speech, shout at the top of one's voice the medical history of crying for a long time, perhaps useful sound is improper, habituation hawks, the medical history that frequent tobacco and wine stimulate, and chronic laryngitis and early stage vocal nodule heterophemia show as discontinuity more, sounding hoarseness will occur slightly for a long time, when the vocal cords pathological changes is obvious, also the persistence hoarseness can occur, and vocal nodule and polyp of vocal cord show as the persistence hoarseness more.
2, with laryngalgia, odynophagia occurs behind cold, fever, may be acute pharyngolaryngitis.Serious laryngalgia does not heal for a long time, also will consider the possibility of tuberculosis of larynx or malignant tumor.
3, sound is sent out mute, even ear-piercing, blocks sense with throat, cough, and sputum mixed with blood, with the cervical region enclosed mass, older patient will watch out for the possibility of laryngeal carcinoma.
4, hoarseness can also appear in vocal cord paralysis.Based on mute, ear-piercing.
5, unexpected crying out of taking place, perhaps low as whisper in sb.'s ear, but laugh and cough can be normal fully, may be the hysteric hoarseness.Check that laryngoscope sees that vocal fold adduction is unusual this moment, but cough back vocal cords can be normally in receipts.
6, foreign bodies in the larynx sense, with cough, sound is easily sent out tired, or the preceding happiness food of sleeping is arranged, or acid often occurs returning, and belch may be backflowing a property laryngitis also, but the patient of the backflowing property laryngitis that has also can only have a kind of symptom.
7, other wound comprises the cricoarytenoid joint dislocation, and the damage of the physical chemistry of throat all can cause hoarseness.
The degree varies of having sore throat can be radiated to ear.Pharyngalgia is obvious, and the time is short, and morbidity is anxious, with heating, may be acute pharyngolaryngitis, acute tonsillitis, angina when swallowing pain, epiglottitis etc., one-sided obvious pharyngalgia may be peritonsillitis or peritonsillar abscess, one-sided fixed slight pharyngalgia, be positioned at a pharyngeal side, get rid of elongated styloid process.With obviously having sore throat, odynophagia, ambiguous in a minute, medical history shorter one will watch out for acute epiglottitis.The degree of the inflammatory pain order of severity general and inflammation is proportional.Pain is lighter, dull pain, and twinge may be the tumor of chronic pharyngolaryngitis or throat with hoarseness.Some diseases in the blood system also can cause significantly has sore throat.
The patient who suffers from rhinitis, pharyngolaryngitis knows, the trouble that rhinitis, pharyngolaryngitis are brought singly is not nasal obstruction, sneeze, throat discomfort, dry cough, foreign body sensation, tonsillitis are arranged, feel dizzy, a series of symptoms such as absent minded, and some patient is also with bronchial asthma.Send out in case nose is sick, also can directly have influence on the health of lung and throat organ.Common complication has that sinusitis, hypopnea, audition weaken, olfactory disorder and nasal polyp.Rhinitis, pharyngolaryngitis are not fatal diseases, but it can bring a lot of miseries to the patient, have a strong impact on normal work of patient and life, if untimely treatment also can bring bigger harm, so the patient must face rhinitis, pharyngolaryngitis and and early treatment.
Summary of the invention
The technical issues that need to address of the present invention just are to provide a kind of pure Chinese medicinal preparation for the treatment of laryngopharyngeal diseases, its heat-clearing and toxic substances removing, relieving sore throat and pain cures mainly that pharyngeal due to the lung sthenia gastropyrexia swollen and ache, heating, thirsty, constipation, and acute tonsillitis, the acute pharyngitis person that sees the above-mentioned symptom.
For addressing the above problem, the present invention adopts following technical scheme:
The present invention treats the Chinese medicine preparation of laryngopharyngeal diseases, and the weight portion proportioning of the preparation raw material of the active component that it is contained is: Radix Achyranthis 5-10 part; Herba Kalimeridis grass 3-6 part; Herba Plantaginis 1-4 part; 1 part of Radix Carpesii.
The weight portion proportioning of the preparation raw material of the active component that the present invention is contained can be Radix Achyranthis 6-8 part; Herba Kalimeridis grass 4-5 part; Herba Plantaginis 2-3 part; 1 part of Radix Carpesii.
Perhaps, the weight portion proportioning of the preparation raw material of the contained active component of the present invention is: 7 parts of Radix Achyranthis; 4 parts of Herba Kalimeridis grasss; 2 parts of Herba Plantaginiss; 1 part of Radix Carpesii.
Chinese medicine preparation of the present invention can be acceptable various dosage forms on oral liquid, granule, drop pill, powder, tablet or capsule and other pharmaceutics.Preferred dosage form is for containing tablet.
The present invention provides a kind of method of described Chinese medicine preparation simultaneously, and it comprises the following steps:
A) according to Radix Achyranthis 5-10 part; Herba Kalimeridis grass 3-6 part; Herba Plantaginis 1-4 part; Radix Carpesii takes by weighing raw materials of traditional Chinese medicinal materials for 1 part, pulverizes standby;
B) described medical material mixing and water adding is decocted, separates, extracts medicinal liquid, concentrating under reduced pressure;
The present invention will mix medical material and decoct with water secondary, each 1.5 hours, first adds 10 times of water gagings decocts, and adds 8 times of water gagings for the second time and decocts collecting decoction, filter, filtrate is 1.25～1.30 extractum when being concentrated into 60 ℃ of relative densities, and vacuum drying, baking temperature are 600C, vacuum is-0.08Mpa, gets dry extract.
The preparation method of buccal tablet of the present invention also comprises the following steps: dried cream powder broken, adds cane sugar powder, dextrin, protein sugar granulation, drying, and granulate adds Mentholum, magnesium stearate, mixing, and tabletting gets buccal tablet.
Among the present invention, Radix Achyranthis bitter in the mouth, acid, property are put down, and heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow, wind-expelling pain-stopping effect are arranged.Be roadside, the hillside weeds of commonly seeing, aboundresources.
Among the present invention, Herba Kalimeridis grass have bring down a fever, detoxifcation, anthelmintic effect.
Among the present invention, Herba Plantaginis is the herb of Plantaginaceae plant Herba Plantaginis and Plantago depressa Willd, includes plantagin, aucubin and plantaglucide etc.The traditional Chinese medical science thinks that it is cold in nature, sweet in the mouth, and function liver heat removing tomorrow, relieving stranguria by diuresis, relieving cough and resolving phlegm is applicable to urinary obstruction, stranguria with turbid discharge leukorrhagia, hematuria, cough ant phlegm, heat-damp in summer dysentery, arthralgia chiefly caused by damp pathogen etc.Pharmacological testing proves: the Herba Plantaginis decoct has the function of regulating stomachial secretion; Make the increase of trachea endocrine and have tangible phlegm-dispelling functions; Pathogenic dermatophytes and some pathogenic bacterium all there is inhibitory action.
Among the present invention, Radix Carpesii hemostasis, diuresis, heat-clearing and toxic substances removing, removing blood stasis, granulation promoting.
Drug matching is particular about: 1 mutual reinforcement between, i.e. the similar medicine fit applications of performance effect can strengthen that it is former effective in cure.2 mutual-assistances, promptly in the medicine fit applications that certain general character is arranged aspect the performance effect, and based on a kind of medicine, another kind of medicine is auxilliary, can improve the curative effect of principal agent thing.3 mutual restraint between two drugs, i.e. a kind of toxic reaction of medicine or side effect can be alleviated by another kind of medicine or eliminate.4 mutual-detoxications, promptly a kind of medicine can alleviate or eliminate the toxicity or the side effect of another kind of medicine.5 mutual inhibitions, i.e. two kinds of drug combinations, a kind of medicine act on mutually with another medicine and cause former powerful reduction, even the forfeiture drug effect.6 is opposite, and promptly two kinds of drug combinations can react or side effect by toxigenicity.
The present invention selects medicine to follow mentioned above principle, select the drug regimen of mutual reinforcement between, the mutual-assistance, the compatibility science, drug effect is remarkable, it selects aboundresources, cheap pure Chinese medicine for use, the treatment laryngopharyngeal diseases can reach heat-clearing and toxic substances removing, relieving sore throat and pain with identifying and correcting, cure mainly that pharyngeal due to the lung sthenia gastropyrexia swollen and ache, heating, thirsty, constipation, and acute tonsillitis, the acute pharyngitis person that sees the above-mentioned symptom, usage and dosage is every day 3 times, each consumption is equivalent to the 1-3g active constituents of medicine.
Points for attention when Chinese medicine preparation of the present invention uses comprise:
1. quit smoking, wine and maror.2. should not take nourishing Chinese medicine simultaneously at period in a medicine.3. surpass 38.5 ℃ and antiadoncus person, the prescription on individual diagnosis of please in time going to the hospital if any hyperpyrexia body temperature.4. there are hypertension, heart disease, diabetes, hepatopathy, nephropathy chronic diseases severe patient under the doctor instructs, to take.5. the 3 days symptoms of taking medicine do not have alleviation, should remove hospital admission.6. child, old person should obey under the doctor instructs.7. to this product allergy sufferers forbidding, the careful usefulness of allergic constitution person.8. forbid when property of drug changes taking.9. the child must use under adult's monitoring.10. please this medicine is placed on the place that the child can not contact.11. as taking other medicines, please Ref Dr or pharmacist before use this product.
The specific embodiment
The preparation of embodiment 1 buccal tablet
1, with Radix Achyranthis 1250g, Herba Kalimeridis grass 715g, Herba Plantaginis 355g, Radix Carpesii 180g, pulverize, mix homogeneously decocts with water secondary, each 1.5 hours, add for the first time 10 times of water gagings and decoct, add 8 times of water gagings for the second time and decoct collecting decoction, filter, filtrate is concentrated into the extractum that relative density is 1.25～1.30 (60 ℃).
2, (baking temperature is 60 ℃, and vacuum is-0.08Mpa), get dry extract with gained extractum vacuum drying.Dried cream powder is broken into the about 375g of dried cream powder, adds cane sugar powder 110g, dextrin 100g, protein sugar 12g, granulate, drying, granulate adds 1g Mentholum, 2g magnesium stearate, mixing, tabletting is made 1000 approximately, promptly gets buccal tablet.
The preparation of embodiment 2 oral liquids
The consumption of each raw medicinal material is: Radix Achyranthis 1800g; Herba Kalimeridis grass 540g; Herba Plantaginis 180g; Radix Carpesii 180g.
The method for preparing extractum by embodiment 1 makes the clear paste that relative density is 1.07-1.09 (60-65 a ℃); Get sucrose 400g and make syrup, merge, stir evenly cooling with above-mentioned clear paste; Get Mentholum 0.2g, benzoic acid is received 3g, and essence is an amount of, behind 70% dissolve with ethanol, adds in the above-mentioned medicinal liquid, stirs evenly, and adjusts total amount to 1000ml, stirs evenly, and leaves standstill, filter, and embedding, sterilization, promptly.
The preparation of embodiment 3 sugar-free granule
The consumption of each raw medicinal material is: Radix Achyranthis 2500g, Herba Kalimeridis grass 1430g, Herba Plantaginis 710g, Radix Carpesii 360g.
The method for preparing extractum by embodiment 1 makes extractum, adds dextrin or dextrin and stevioside, and again through granulating, dry, the granulate branch bag of packing into becomes granule, every packed medicine 3g.
The preparation of embodiment 4 tablets
The consumption of each raw medicinal material is: Radix Achyranthis 1080g; Herba Kalimeridis grass 900g; Herba Plantaginis 360g; Radix Carpesii 180g.
The method for preparing extractum by embodiment 1 makes extractum, and drying is pulverized, and adds dextrin 100g, carboxymethyl starch sodium 22g, Mentholum 1g, granulate, and drying, granulate adds the 2g magnesium stearate, tabletting, compacting is in blocks, promptly.
The preparation of embodiment 5 capsules
The consumption of each raw medicinal material is: Radix Achyranthis 1250g; Herba Kalimeridis grass 715g; Herba Plantaginis 355g; Radix Carpesii 180g.
The method for preparing extractum by embodiment 1 makes extractum, and drying is pulverized, and makes granule, drying, and granulate incapsulates, and every powder charge is equivalent to primary crude drug 2.5g, promptly gets capsule.
The preparation of embodiment 6 granules
The consumption of each raw medicinal material is: Radix Achyranthis 2500g, Herba Kalimeridis grass 1430g, Herba Plantaginis 710g, Radix Carpesii 360g.
The method for preparing extractum by embodiment 1 makes extractum, adds dextrin or dextrin and sweeting agent, again through granulation, dry, the granulate branch bag of packing into becomes granule, every packed medicine 5g.
The preparation of embodiment 6 tablets
The consumption of each raw medicinal material is: Radix Achyranthis 1250g, Herba Kalimeridis grass 715g, Herba Plantaginis 355g, Radix Carpesii 180g.
The method for preparing extractum by embodiment 1 makes extractum, is ground into the about 375g of dried cream powder, adds dextrin 100g, carboxymethyl starch sodium 22g, Mentholum 1g, granulate, and drying, granulate adds the 2g magnesium stearate, and tabletting is made 1000, promptly approximately.
The preparation of embodiment 7 powders
The consumption of each raw medicinal material is: Radix Achyranthis 1440g, Herba Kalimeridis grass 720g, Herba Plantaginis 540g, Radix Carpesii 180g.
With above four Chinese medicine, be ground into fine powder, sieve, evenly, promptly.
The preparation of embodiment 8 pills
The consumption of each raw medicinal material is: Radix Achyranthis 1250g, Herba Kalimeridis grass 715g, Herba Plantaginis 355g, Radix Carpesii 180g.
With above four Chinese medicine, be ground into fine powder, sieve, evenly, every 100g powder adds refined honey 110～130g and makes big honeyed pills, promptly.
Claims (8)
1, a kind of Chinese medicine preparation for the treatment of laryngopharyngeal diseases is characterized in that: the weight portion proportioning of the preparation raw material of the active component that it is contained is: Radix Achyranthis 5-10 part; Herba Kalimeridis grass 3-6 part; Herba Plantaginis 1-4 part; 1 part of Radix Carpesii.
2, the Chinese medicine preparation of treatment laryngopharyngeal diseases as claimed in claim 1 is characterized in that: the weight portion proportioning of the preparation raw material of the active component that it is contained is: Radix Achyranthis 6-8 part; Herba Kalimeridis grass 4-5 part; Herba Plantaginis 2-3 part; 1 part of Radix Carpesii.
3, the Chinese medicine preparation of treatment laryngopharyngeal diseases as claimed in claim 1 is characterized in that: the weight portion proportioning of the preparation raw material of the active component that it is contained is: 7 parts of Radix Achyranthis; 4 parts of Herba Kalimeridis grasss; 2 parts of Herba Plantaginiss; 1 part of Radix Carpesii.
4, as the Chinese medicine preparation of the arbitrary described treatment laryngopharyngeal diseases of claim 1-3, it is characterized in that described Chinese medicine preparation is acceptable various dosage forms on oral liquid, granule, drop pill, powder, tablet, buccal tablet or capsule and other pharmaceutics.
5, as the Chinese medicine preparation of the arbitrary described treatment laryngopharyngeal diseases of claim 1-3, it is characterized in that described Chinese medicine preparation is a buccal tablet.
6, a kind of preparation is characterized in that as the method for Chinese medicine preparation as described in claim 1-5 arbitrary it comprises the following steps:
A) according to Radix Achyranthis 5-10 part; Herba Kalimeridis grass 3-6 part; Herba Plantaginis 1-4 part; My god
Name takes by weighing raw materials of traditional Chinese medicinal materials for smart 1 part, pulverizes standby;
B) described medical material mixing and water adding is decocted, separates, extracts medicinal liquid, concentrating under reduced pressure.
7, preparation method as claimed in claim 6, it is characterized in that it comprises the following steps: the mixing medical material is decocted with water secondary, each 1.5 hours, first adds 10 times of water gagings decocted, adding for the second time 8 times of water gagings decocts, collecting decoction filters, and filtrate is 1.25～1.30 extractum when being concentrated into 60 ℃ of relative densities, vacuum drying, baking temperature is 600C, and vacuum is-0.08Mpa, gets dry extract.
8, preparation method as claimed in claim 7, it is broken to it is characterized in that it also comprises the following steps: dried cream powder, adds cane sugar powder, dextrin, protein sugar granulation, drying, and granulate adds Mentholum, magnesium stearate, mixing, tabletting must contain tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510130514 CN1813925A (en) | 2005-12-13 | 2005-12-13 | Chinese medicine formulation for treating pharynx and larynx disease and its preparing method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200510130514 CN1813925A (en) | 2005-12-13 | 2005-12-13 | Chinese medicine formulation for treating pharynx and larynx disease and its preparing method |
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| CN1813925A true CN1813925A (en) | 2006-08-09 |
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| CN 200510130514 Pending CN1813925A (en) | 2005-12-13 | 2005-12-13 | Chinese medicine formulation for treating pharynx and larynx disease and its preparing method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008530A (en) * | 2009-09-08 | 2011-04-13 | 梁锦荣 | Nasal drop or nasal spray for treating tonsillitis and application method thereof |
| CN102366455A (en) * | 2011-11-26 | 2012-03-07 | 李新欣 | Traditional Chinese medicine for treating swelling and sore throat |
| CN102416095A (en) * | 2011-11-21 | 2012-04-18 | 湖南时代阳光药业股份有限公司 | Chinese medicine composition for treating amygdalitis and pharyngitis |
-
2005
- 2005-12-13 CN CN 200510130514 patent/CN1813925A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008530A (en) * | 2009-09-08 | 2011-04-13 | 梁锦荣 | Nasal drop or nasal spray for treating tonsillitis and application method thereof |
| CN102008530B (en) * | 2009-09-08 | 2014-01-29 | 梁锦荣 | Nasal drop or nasal spray for treating tonsillitis and application method thereof |
| CN102416095A (en) * | 2011-11-21 | 2012-04-18 | 湖南时代阳光药业股份有限公司 | Chinese medicine composition for treating amygdalitis and pharyngitis |
| CN102366455A (en) * | 2011-11-26 | 2012-03-07 | 李新欣 | Traditional Chinese medicine for treating swelling and sore throat |
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