CN1813878A - Oral Chinese medicine formulation for treating pain caused by qi-blood ecchymoma - Google Patents
Oral Chinese medicine formulation for treating pain caused by qi-blood ecchymoma Download PDFInfo
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- CN1813878A CN1813878A CN 200510022706 CN200510022706A CN1813878A CN 1813878 A CN1813878 A CN 1813878A CN 200510022706 CN200510022706 CN 200510022706 CN 200510022706 A CN200510022706 A CN 200510022706A CN 1813878 A CN1813878 A CN 1813878A
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Abstract
The present invention relates to an oral Chinese medicine preparation for effectively curing pain due to stagnancy of qi and blood stasis. It is made up by using (by weight portion) 8-12 portions of corydalis tuber, 4-6 portions of Chinese angelica root and 4-6 portions of ligusticum root through a certain preparation process. Said Chinese medicine preparation has the function of promoting blood circulation, removing blood stasis, promoting circulation of qi and relieving pain and can obtain obvious therapeutic effect for curing the diseases of headache due to wind-cold, dizziness, epigastralgia, pain of lower addomen, dysmenorrheal and arthralgia, etc.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of pain, be specifically related to a kind of pain caused oral Chinese medicine preparation of stagnation of QI-blood for the treatment of.
Background technology
Pain is one of common symptom of various diseases, modal have diseases such as headache, pained, chest pain, costalgia, gastric abscess, stomachache, lumbago, amenorrhea dysmenorrhea and rheumatism splenalgia, in order to remove patient's sufferings, vast medical worker is seeking effective medicine, that produces, sells and uses on the domestic market at present has Western medicine preparations such as aspirin, indometacin and ibuprofen, because these Western medicine preparations have side effect to human body, so its use is very limited; Minority Chinese medicine antalgic and inflammation relieving medicine such as gastrodia tuber and fleece-flower root sheet, YUANHU ZHITONG PIAN, huoxue zhitong powder, huoxue zhitong san and QUFENG ZHITONG PIAN etc. lay particular emphasis on the medicine of a certain cause of disease more, can not satisfy the needs of extensive patients.
Summary of the invention
The objective of the invention is for overcoming disadvantages of background technology, and provide a kind of good effect, safe without toxic side effect and the stronger pain caused oral Chinese medicine preparation of treatment stagnation of QI-blood of specific aim of treatment pain.
The present invention realizes by the following technical solutions: make that medical material in the raw material of this oral Chinese medicine preparation is formed and weight portion is:
4～6 parts of 4～6 parts of Rhizoma Chuanxiongs of 8～12 parts of Radix Angelicae Sinensis of Rhizoma Corydalis.
Described oral Chinese medicine preparation is drop pill, capsule, tablet, pill, electuary, granule, unguentum or oral solutions.
Rhizoma Corydalis has and strengthens the analgesic effect among the side of the present invention, and Radix Angelicae Sinensis and Rhizoma Chuanxiong compatibility can be strengthened the enriching blood of Radix Angelicae Sinensis, invigorate blood circulation, the function of the invigorating blood circulation of pain relieving and Rhizoma Chuanxiong, circulation of qi promoting, wind-expelling pain-stopping, and can reduce the toxicity of each single medicinal material.Full side has the function of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, and for headache, the dizziness that wind and cold causes, gastric abscess is attacked and scurried both sides of the chest pain, asthenic cold type and dysmenorrheal caused by qi stagnation and blood stasis, and limbs joint pains etc. are evident in efficacy.
Advantage of the present invention is: the present invention is a pure Chinese medicinal preparation, function with blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, the headache, the dizziness that cause for wind and cold, aversion to cold, gastric abscess is attacked and is scurried both sides of the chest pain, lower abdominal pain, asthenic cold type and dysmenorrheal caused by qi stagnation and blood stasis, lower abdomen pain before and after menstrual period, limbs joint pains etc. are evident in efficacy, preparation dose of the present invention is little, effective ingredient discharges easily, absorbs soon, and drug effect is not fully exerted, bioavailability is improved, be easy to carry, be easy to take, be beneficial to suitability for industrialized production and have no side effect.
The specific embodiment
Embodiment 1
Make that medical material in the raw material of this embodiment is formed and weight is:
Rhizoma Corydalis 10 gram Radix Angelicae Sinensis 5 gram Rhizoma Chuanxiongs 5 grams.
The preparation technology of present embodiment is: after earlier the 10g Rhizoma Corydalis being pulverized, add 80% ethanol that 8 times of amounts contain 5% acetic acid, and reflux, extract, 2 times, each 2 hours, filter, merge and filter, standby; Take by weighing each 5g of Radix Angelicae Sinensis and Rhizoma Chuanxiong again, add 6 times of amount 80% ethanol, reflux, extract, 2 times, each 1 hour, filter, merge and filter, after above-mentioned Rhizoma Corydalis filtrate merging, reclaim ethanol, be condensed into the thick paste of relative concentration 1.30 (50～60 ℃), ratio in polyethylene glycol 6000 and thick paste takes by weighing polyethylene glycol 6000 at 4: 1, slowly adds thick paste after the polyethylene glycol 6000 fusing, is mixed, make drop pill, every ball 30mg makes 1000, then packing.
Embodiment 2
Make that medical material in the raw material of this embodiment is formed and weight is:
Rhizoma Corydalis 12 gram Radix Angelicae Sinensis 4 gram Rhizoma Chuanxiongs 4 grams.
Its preparation technology: after earlier the 12g Rhizoma Corydalis being pulverized, add 80% ethanol that 8 times of amounts contain 5% acetic acid, reflux, extract, 2 times, each 2 hours, filter, merge and filter, standby; Take by weighing each 4g of Radix Angelicae Sinensis and Rhizoma Chuanxiong again, add 6 times of amount 80% ethanol, reflux, extract, 2 times, each 1 hour, filter, merge and filter, after above-mentioned Rhizoma Corydalis filtrate merging, reclaim ethanol, be condensed into the thick paste of relative concentration 1.30 (50～60 ℃), ratio in polyethylene glycol 6000 and thick paste takes by weighing polyethylene glycol 6000 at 4: 1, slowly adds thick paste after the polyethylene glycol 6000 fusing, is mixed, make drop pill, every ball 30mg makes 1000, then packing.
Embodiment 3
Make that medical material in the raw material of this embodiment is formed and weight is:
Rhizoma Corydalis 8 gram Radix Angelicae Sinensis 6 gram Rhizoma Chuanxiongs 6 grams.
Its preparation technology: after earlier the 8g Rhizoma Corydalis being pulverized, add 80% ethanol that 8 times of amounts contain 5% acetic acid, reflux, extract, 2 times, each 2 hours, filter, merge and filter, standby; Take by weighing each 6g of Radix Angelicae Sinensis and Rhizoma Chuanxiong again, add 6 times of amount 80% ethanol, reflux, extract, 2 times, each 1 hour, filter, merge and filter, after above-mentioned Rhizoma Corydalis filtrate merging, reclaim ethanol, be condensed into the thick paste of relative concentration 1.30 (50～60 ℃), ratio in polyethylene glycol 6000 and thick paste takes by weighing polyethylene glycol 6000 at 4: 1, slowly adds thick paste after the polyethylene glycol 6000 fusing, is mixed, make drop pill, every ball 30mg makes 1000, then packing.
This product is the dark-brown drop pill, and special fragrance is arranged, and the high-density plastic is bottled, 30mg/ grain, 100/bottle; Its usage and dosage is: sublingual administration or oral, and each 10～15 of usual amounts, every day 2～3 times, 3 is a course of treatment, available 2～3 courses of treatment.
The present invention's " profound pain-relieving dripping pill of returning " has analgesia, antiinflammatory, the blood coagulation resisting function of highly significant, P＜0.01, normal pressure resisting oxygen lack P＜0.01 of highly significant in addition; The clinical research observation gastric abscess: 30 examples are organized in treatment, matched group 30 examples; Headache: 30 examples are organized in treatment, matched group 30 examples; Dysmenorrhea: 30 examples are organized in treatment, matched group 30 examples, the result the analysis showed that through Ridit: the effective percentage of gastric abscess is 95.6%, P＜0.01, the effective percentage of dysmenorrhea is 96.6%, P＜0.01, the effective percentage of headache is 96.7%, P＜0.01, and through hospital all of Tang of The Fourth Military Medical University of PLA, the 3rd hospital of PLA and the several years clinical practice of PLA Chengyang 323 hospitals, through the maximum resistance test of acute toxicity, this medicine maximum tolerated dose on the one is 30g/kg again, be equivalent to 600 times of clinical Coming-of-Age Day specified volume, show that it is safe and reliable that this medicine uses in the clinical dose scope of regulation.
Claims (3)
1, a kind of pain caused oral Chinese medicine preparation of stagnation of QI-blood for the treatment of is characterized in that making that medical material in the raw material of this medicine is formed and weight portion is:
4～6 parts of 4～6 parts of Rhizoma Chuanxiongs of 8～12 parts of Radix Angelicae Sinensis of Rhizoma Corydalis.
2, a kind of pain caused oral Chinese medicine preparation of stagnation of QI-blood for the treatment of according to claim 1 is characterized in that making that medical material in the raw material of this medicine is formed and weight portion is:
5 parts of 5 parts of Rhizoma Chuanxiongs of 10 parts of Radix Angelicae Sinensis of Rhizoma Corydalis.
3, a kind of pain caused oral Chinese medicine preparation of stagnation of QI-blood for the treatment of according to claim 1 and 2 is characterized in that described oral Chinese medicine preparation is drop pill, capsule, tablet, pill, electuary, granule, unguentum or oral solutions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100227069A CN100427114C (en) | 2005-12-23 | 2005-12-23 | Oral Chinese medicine formulation for treating pain caused by qi-blood ecchymoma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100227069A CN100427114C (en) | 2005-12-23 | 2005-12-23 | Oral Chinese medicine formulation for treating pain caused by qi-blood ecchymoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1813878A true CN1813878A (en) | 2006-08-09 |
| CN100427114C CN100427114C (en) | 2008-10-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100227069A Expired - Fee Related CN100427114C (en) | 2005-12-23 | 2005-12-23 | Oral Chinese medicine formulation for treating pain caused by qi-blood ecchymoma |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584848B (en) * | 2009-05-26 | 2011-03-23 | 韩树华 | Chinese medicament for treating qi stagnation, food accumulation and cold bind type bellyache diseases |
| CN102670732A (en) * | 2012-05-29 | 2012-09-19 | 陕西新药技术开发中心 | Medicament for treating headache |
| CN104001079A (en) * | 2014-06-06 | 2014-08-27 | 刘维宏 | Hot-wet compression Chinese herbal liquid medicament for treating phlebitis in chest wall and preparation method thereof |
| CN105148084A (en) * | 2015-10-16 | 2015-12-16 | 烟台瑞智生物医药科技有限公司 | Traditional Chinese medicine composition for treating dysmenorrheal caused by qi stagnancy and blood stasis |
| CN109528842A (en) * | 2018-08-22 | 2019-03-29 | 柳倩 | A kind of knee numbness disappears tincture formula and its application method |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088803A (en) * | 1993-01-01 | 1994-07-06 | 张金生 | The quick-acting analgesic tincture of treatment constitutional soft tissue ache |
| CN1314427C (en) * | 2002-12-12 | 2007-05-09 | 郭士全 | Medicine for treating menalgia |
-
2005
- 2005-12-23 CN CNB2005100227069A patent/CN100427114C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584848B (en) * | 2009-05-26 | 2011-03-23 | 韩树华 | Chinese medicament for treating qi stagnation, food accumulation and cold bind type bellyache diseases |
| CN102670732A (en) * | 2012-05-29 | 2012-09-19 | 陕西新药技术开发中心 | Medicament for treating headache |
| CN102670732B (en) * | 2012-05-29 | 2014-12-03 | 陕西新药技术开发中心 | Medicament for treating headache |
| CN104001079A (en) * | 2014-06-06 | 2014-08-27 | 刘维宏 | Hot-wet compression Chinese herbal liquid medicament for treating phlebitis in chest wall and preparation method thereof |
| CN105148084A (en) * | 2015-10-16 | 2015-12-16 | 烟台瑞智生物医药科技有限公司 | Traditional Chinese medicine composition for treating dysmenorrheal caused by qi stagnancy and blood stasis |
| CN109528842A (en) * | 2018-08-22 | 2019-03-29 | 柳倩 | A kind of knee numbness disappears tincture formula and its application method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100427114C (en) | 2008-10-22 |
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