CN1794972A - 包含植物提取物的用于化妆品的活性制剂 - Google Patents
包含植物提取物的用于化妆品的活性制剂 Download PDFInfo
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- CCEKAJIANROZEO-UHFFFAOYSA-N sulfluramid Chemical group CCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F CCEKAJIANROZEO-UHFFFAOYSA-N 0.000 description 1
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- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
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- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
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- Dispersion Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及用在化妆产品中的活性成分组合物，所述组合物包含植物提取物并特别对抗游离自由基。所述活性成分组合物是不含脂质体的植物提取物的基于醇的混和物，其由介于0.1－2重量％之间的绿咖啡豆的提取物，介于0.1－2重量％之间的Camellia sinensis的叶提取物，介于0.1－2重量％之间的水黄皮的提取物和介于0.1－2重量％之间的Angelicaarchangelica的根的提取物以及用于获得总100重量％的剩余含量的单价C2－C5醇所组成。所述自由基保护因子的量介于1,400和2,900×1014的游离自由基/mg之间。
Description
本发明涉及用于化妆品的活性制剂，其包含植物提取物并且具有特殊的抗-自由基性质。
从WO 99/66881，已知具有高自由基保护因子的化妆品活性制剂，所述制剂包含封装于微荚膜中的来自Quebracho blanco的树皮的提取物和蚕提取物作为主要成分，所述提取物在凝胶中与磷脂一起进行提供并在所述凝胶中形成相关的复合物(complex)。前述的活性复合物还可以包含另外的成分，例如，植物提取物。所提及的植物提取物特别包括从咖啡豆和当归根中获得的那些。取决于加入的活性制剂的量，所述组合具有范围介于100和10,000之间的自由基保护因子并且它们用于其中的化妆品制剂具有介于40-200的自由基保护因子。
本发明的目标是提供用于化妆品的组合物，不使用包封脂质体可以容易地制备所述组合物并且其同时具有高的自由基保护因子，但是所述组合物可以更容易得多地与其它化妆品的成分结合，并且其还适合于生产香水和喷雾剂。
按照本发明，所述活性制剂由植物提取物与醇基质的混合物组成，所述混和物由0.1-2重量％的绿咖啡豆的提取物，0.1-2重量％的Camelliasinensis的叶提取物，0.1-2重量％的水黄皮(Pongamia pinnata)的提取物和0.1-2重量％的Angelica archangelica的根的提取物以及补足余数到100重量％的单价C2-C5醇所组成。所述提取物混合物没有脂质体并且具有介于1,400和2,900×1014的自由基/毫克范围内的自由基保护因子。
前述提取物是醇或水-醇提取物，优选地是醇提取物。提取温度范围介于18和28℃之间。水黄皮的提取物获自整个植物。
相对于化妆品的总重，所述提取物混合物可以组成化妆品的0.1-10重量％，优选地0.1-5重量％。通过以电子旋转共振(ESR)测量测试物质(S1)的溶液中的游离自由基的数量并按照等式RPF＝(RC×RF)/PI将其与化妆品活性制剂的ESR测量结果进行比较来确定，已经发现这种活性混合物具有意料外的约1,400-2,900×1014自由基/mg的高自由基保护因子(RPF)，等式中RF＝(S1-S2)/S1；RC＝测试物质的浓度(自由基/ml)；PI＝活性制剂的浓度(mg/ml)(按照WO 99/66881测量)。
以这种方式发现的RPF相当大地高于WO 99/66881活性制剂的测定为1,255的RPF。
还已经发现如果所述化妆品组合物以介于0.5-2重量％之间范围的优选浓度包含所述活性制剂，包含按照本发明的活性制剂的化妆品组合物将具有60-140×1014自由基/mg的自由基保护因子，此值相当大的高于WO99/66881的实施例中所测定的35-49×1014的值。
可以将按照本发明的活性制剂用于W/O或O/W乳剂，凝胶或凝胶乳剂中。其在香水或喷雾剂中的应用是特别有利的。从WO 99/66881中已知的活性制剂总是与凝胶结合并且此外，所述活性制剂被封装于脂质体内，这常使这种制剂非常难以雾化；因而，具有高自由基保护因子的这些制剂几乎不能用于这种应用。相反，由于不是必须产生脂质体，按照本发明的活性制剂的醇溶液可以更容易地进行制备，其具有高自由基保护因子，可以将其掺入喷雾剂或香水应用中并且毫无困难的被使用者进行雾化。
还可以将按照本发明的活性制剂与其它化妆品助剂和活性剂进行结合并对其进行加工以获得适合于应用的形式。
这些助剂包括水、防腐剂、着色剂、具有着色作用的颜料、增厚剂、芳香剂、醇、多元醇、酯、电解质、形成凝胶的试剂、极性和非极性油、聚合物、共聚物、乳剂、稳定剂。
化妆品活性剂包括例如无机和有机防晒剂、另外的自由基清除剂、增湿剂、维生素、酶、另外的基于植物的活性剂、聚合物、黑素、抗氧化剂、抗炎的天然活性剂。
其后将以实施例的方式更详细地阐述本发明。除非另外特别指出，所有的量为重量％形式。
实施例1皮肤增湿香脂
部分A
水 适量加到100
甘油 2.0
丁二醇 2.0
乙二胺四乙酸四钠 0.1
防腐剂 0.4
pH调节剂 0.3
部分B
Beheneth-25 3.3
十六烯芳醇(Cetearyl Alcohol) 2.7
碳酸二辛酯(Dicapryl Carbonate) 8.5
牛油树脂 7.2
苯氧基乙醇 0.9
改性的玉米淀粉粉末 3.0
Dimethicone 1.4
SimulgelNS 3.5
部分C
着色剂 0.1
火山起源的水** 1.0
肽棕榈酰-甘氨酸-组氨酸-赖氨 0.5
酸
来自植物的醇提取物的混合物* 0.2
海茴香提取物 0.5
水解的大豆蛋白 1.0
二苯酮-4(用于着色剂的) 0.4
*由0.2％重量的咖啡豆的种子，0.2％重量的Camellia sinensis的叶，0.2％重量的水黄皮，0.2％重量的当归根和99.8重量的％乙醇组成。
**具有如下的盐浓度：
0.01-0.05mg/l铁，100-300mg/l钾，1,000-2,000mg/l钠，80-200mg/l镁，50-150mg/l钙，50-150mg/l硅(作为SiO2)，0.01-0.1mg/l磷，0.001-0.005mg/l硒，0.01-0.03mg/l锌。
将部分A和部分B于约60℃单独混合，将部分C在约35℃混和，并且将所有的三部分相互结合，同时在约35℃搅拌。
皮肤香脂的RPF为68(×1014自由基/mg)。
实施例2香水
乙醇 适量加足到100
来自植物的醇提取物的混合物* 9.5
香水 8
RPF＝137.
实施例3喷雾剂
乙醇 适量加足到100
来自植物的醇提取物的混合物* 5
推进剂气体 38
RPF＝93.
所述喷雾剂极易于操作，显示了非常好的液滴分布并不会导致象其中植物提取物被封装入脂质体的用作比较的喷雾剂那样的问题。
Claims (5)
1.一种用于化妆品的具有植物提取物的活性制剂，其包含植物提取物与醇基质的无脂质体的混合物，其由0.1-2重量％的绿咖啡豆的提取物，0.1-2重量％的Camellia sinensis的叶提取物，0.1-2重量％的水黄皮的提取物和0.1-2重量％的Angelica archangelica的根的提取物以及补足余数到100重量％的单价C2-C5醇所组成，其中自由基保护因子的范围介于1,400和2,900×1014的自由基/mg之间，并且其中前述浓度是相对于活性制剂的总重量。
2.按照权利要求1的活性制剂，其中所述活性制剂是植物提取物与醇基质的混合物，其由0.2％重量的绿咖啡豆的提取物，0.2％重量的Camelliasinensis的叶提取物，0.2％重量的水黄皮提取物和0.2％重量的Angelicaarchangelica的根和99.2重量％的乙醇组成。
3.按照权利要求1的活性制剂，其中在化装品制剂中以介于0.1-10重量％之间的范围的浓度提供所述活性制剂。
4.按照权利要求3的活性制剂，其中在化妆品制剂中以介于0.1-10重量％之间的浓度范围提供所述活性制剂，并且所述化妆品制剂的自由基保护因子范围介于60-140×1014自由基/mg之间。
5.按照权利要求1的活性制剂，其中以喷雾剂或香水形式提供所述活性制剂。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10325156.1 | 2003-05-28 | ||
| DE10325156A DE10325156A1 (de) | 2003-05-28 | 2003-05-28 | Wirkstoffzubereitung mit Pflanzenextrakten für Kosmetika |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1794972A true CN1794972A (zh) | 2006-06-28 |
| CN100435782C CN100435782C (zh) | 2008-11-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004800145927A Expired - Lifetime CN100435782C (zh) | 2003-05-28 | 2004-05-21 | 包含植物提取物的用于化妆品的活性制剂 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7361372B2 (zh) |
| EP (1) | EP1651183B1 (zh) |
| JP (1) | JP4467573B2 (zh) |
| KR (1) | KR20060022251A (zh) |
| CN (1) | CN100435782C (zh) |
| AT (1) | ATE390914T1 (zh) |
| DE (2) | DE10325156A1 (zh) |
| ES (1) | ES2307016T3 (zh) |
| WO (1) | WO2004105706A1 (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103813776A (zh) * | 2011-07-14 | 2014-05-21 | 科蒂德国有限责任公司 | 防红外辐射的化妆品用途 |
| CN107252402A (zh) * | 2017-06-09 | 2017-10-17 | 安徽启威生物科技有限公司 | 一种基于水黄皮花提取物的天然纳米抗菌免洗洗手液 |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1615506E (pt) | 2003-04-16 | 2014-06-25 | Vdf Futureceuticals | Produtos de cereja de café com baixo teor em micotoxinas e métodos para a sua produção |
| AU2003225038A1 (en) | 2003-04-16 | 2004-11-26 | Vdf Futureceuticals | Methods for coffee cherry products |
| ES2388606T3 (es) | 2004-04-08 | 2012-10-16 | Vdf Futureceuticals, Inc. | Procedimientos y composiciones cosméticas de baya de café |
| DE102004062170B3 (de) * | 2004-12-17 | 2006-06-08 | Lancaster Group Gmbh | Kosmetisches Präparat zur Bräunungsverlängerung und die Verwendung des Präparates |
| DE102005021806A1 (de) * | 2005-05-04 | 2006-11-16 | Lancaster Group Gmbh | Verwendung von radikalfangenden Substanzen zur Behandlung von Zuständen mit erhöhter Hauttemperatur, insbesondere zur antipyretischen Behandlung |
| EP1877095B1 (en) | 2005-05-04 | 2009-05-27 | Coty Prestige Lancaster Group GmbH | The use of free radical scavengers for protecting and treating skin and hair damages caused by chemotherapy |
| DE102006058394B3 (de) | 2006-12-07 | 2008-06-26 | Coty Prestige Lancaster Group Gmbh | Hautbräunungs-Basisformulierung mit DHA |
| DE102007051614A1 (de) * | 2007-10-24 | 2009-04-30 | Coty Prestige Lancaster Group Gmbh | Retinolhaltiges Kosmetikprodukt |
| DE102008004665B4 (de) | 2008-01-11 | 2015-09-24 | Coty Prestige Lancaster Group Gmbh | Kosmetische Zusammensetzung mit Anti-Alterungswirkung |
| DE102008014289A1 (de) | 2008-03-11 | 2009-09-17 | Coty Prestige Lancaster Group Gmbh | Kosmetikum mit Anti-Alterungswirkung |
| DE102008022041A1 (de) | 2008-04-29 | 2009-11-05 | Coty Prestige Lancaster Group Gmbh | Kosmetisches Erzeugnis mit verzögerter Retinolfreisetzung |
| ES2806139T3 (es) * | 2013-10-03 | 2021-02-16 | Suntory Holdings Ltd | Glicósido de ácido orgánico contenido en los granos de café |
| AU2016228973A1 (en) * | 2015-03-06 | 2017-09-28 | Natura Cosméticos S.A. | Cosmetic antioxidant formulation for topical use comprising an association of plant extracts, use thereof |
| US11596610B2 (en) * | 2020-03-12 | 2023-03-07 | Higher Options Global, Inc. | Compositions in support of health and mental accuity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19860754B4 (de) * | 1998-06-24 | 2004-10-28 | Coty B.V. | Kosmetische Zubereitung |
| ATE285223T1 (de) * | 1999-10-08 | 2005-01-15 | Coty Bv | Kosmetische wirkstoffzubereitung mit synergistisch erhöhtem radikalschutzfaktor |
-
2003
- 2003-05-28 DE DE10325156A patent/DE10325156A1/de not_active Withdrawn
-
2004
- 2004-05-21 US US10/558,441 patent/US7361372B2/en active Active
- 2004-05-21 AT AT04734243T patent/ATE390914T1/de not_active IP Right Cessation
- 2004-05-21 DE DE502004006729T patent/DE502004006729D1/de not_active Expired - Lifetime
- 2004-05-21 CN CNB2004800145927A patent/CN100435782C/zh not_active Expired - Lifetime
- 2004-05-21 KR KR1020057022737A patent/KR20060022251A/ko not_active Application Discontinuation
- 2004-05-21 JP JP2006529905A patent/JP4467573B2/ja not_active Expired - Fee Related
- 2004-05-21 WO PCT/EP2004/005542 patent/WO2004105706A1/de active IP Right Grant
- 2004-05-21 EP EP04734243A patent/EP1651183B1/de not_active Expired - Lifetime
- 2004-05-21 ES ES04734243T patent/ES2307016T3/es not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103813776A (zh) * | 2011-07-14 | 2014-05-21 | 科蒂德国有限责任公司 | 防红外辐射的化妆品用途 |
| CN103813776B (zh) * | 2011-07-14 | 2016-12-21 | 科蒂德国有限责任公司 | 防红外辐射的化妆品用途 |
| CN107252402A (zh) * | 2017-06-09 | 2017-10-17 | 安徽启威生物科技有限公司 | 一种基于水黄皮花提取物的天然纳米抗菌免洗洗手液 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE10325156A1 (de) | 2004-12-23 |
| US20060251607A1 (en) | 2006-11-09 |
| US7361372B2 (en) | 2008-04-22 |
| CN100435782C (zh) | 2008-11-26 |
| KR20060022251A (ko) | 2006-03-09 |
| JP2006528953A (ja) | 2006-12-28 |
| EP1651183B1 (de) | 2008-04-02 |
| DE502004006729D1 (de) | 2008-05-15 |
| JP4467573B2 (ja) | 2010-05-26 |
| EP1651183A1 (de) | 2006-05-03 |
| WO2004105706A1 (de) | 2004-12-09 |
| ES2307016T3 (es) | 2008-11-16 |
| ATE390914T1 (de) | 2008-04-15 |
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