CN1762484A

CN1762484A - Bolus for treating hepatitis A, hepatitis B, chronic hepatitis and preparation method thereof

Info

Publication number: CN1762484A
Application number: CNA2005101133567A
Authority: CN
Inventors: 陈道卿
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-09-28
Filing date: 2005-09-28
Publication date: 2006-04-26
Anticipated expiration: 2025-09-28
Also published as: CN1321678C

Abstract

The invention relates to a bolus for treating hepatitis A, hepatitis B, chronic hepatitis and preparation method, wherein the raw material comprises the following ingredients (by weight ratio): pseudostellaria root 1 part, schisandra fruit 1 part, rhubarb horsetails 2 parts, rhizome of Chinese paris 1 part, white peony root1 parts, alaum 0.75 part, curcuma root 1 part, malan flower 2 parts. The invention also provides the process for preparing the pill.

Description

A kind of pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease and preparation method thereof

Technical field

The present invention relates to a kind of medicine pill for the treatment of hepatitis A disease, hepatitis B and chronic hepatitis disease and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Acute hepatitis A is sick and the Type B viral hepatitis disease is higher at the sickness rate in vast rural area, is thoroughly cured after the morbidity and to transfer the patient of chronic hepatitis or chronic persistent hepatitis disease to quite a few.Because most of hepatitis disease has infectiousness, therefore the health to people causes great threat, especially makes peasant disability in the rural area, brings serious burden for family and society.

In order to treat hepatitis A disease, hepatitis B and chronic hepatitis disease, often want hospitalization, take relevant medicine, generally more easily cure in acute stage, if transfer chronic hepatitis or hepatitis interstitialis chronica to, just compare refractory.The present inventor is a traditional Chinese medical science, long-term diagnosis and treatment hepatitis patient, on the basis of secret prescription handed down in the family from generation to generation, experience in conjunction with a large amount of patients of diagnosis and treatment, invent out a kind of pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease disclosed in this invention, it is named as the yellow enzyme liver poison clearing pellet of treatment hepatitis A disease, hepatitis B and chronic hepatitis disease in actual applications.

Summary of the invention

The objective of the invention is to overcome the deficiencies in the prior art and defective, needs at vast hepatitis A disease, hepatitis B and chronic hepatitis patient, a kind of pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease is proposed, this pill has supplementing QI and nourishing YIN, enzyme, promoting the function of the gallbladder to alleviate jaundice, removing blood stasis with potent drugs Sal Nitri, removing dampness antidotal effect fall in heat clearing away, being used for the treatment of chronic hepatitis B, chronic persistent hepatitis or active hepatitis transaminase raises, and jaundice is not moved back for a long time, tangible curative effect is arranged, cholecystitis and cholelithiasis are also had curative effect preferably.This medicine low price, the patient who is particularly suitable for vast rural area and low-income group takes.

For reaching above-mentioned purpose, the invention provides a kind of pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease, the weight portion prescription of its raw material is:

1 part of 1 part of Rhizoma Paridis of Radix Pseudostellariae 1 part of Radix Et Rhizoma Rhei of 1 part of distant five tastes

2 parts of 1 portion of flaggers of 0.75 portion of Radix Curcumae of 1 part of Alumen of the Radix Paeoniae Alba

The mix powder of raw material adds 300～500 milliliters modulation concentrated solution more than each kilogram, is modulated to the pill of 6～10 ball/grams.

Wherein, the parts by weight of raw materials prescription of described modulation concentrated solution is:

1 part of 2 parts of Cornu Bubali slice of 2 portions of Herba Sedis of 2 parts of Rhizoma Polygoni Cuspidati of Herba Hyperici Japonici

1 part of 1 portion of Herba Artemisiae Scopariae of 1 portion of Ganoderma of Radix Sophorae Flavescentis

The mixture of raw material adds decocting system, filters, is condensed into 300～500 milliliters modulation concentrated solution more than each kilogram.

The Mel that wherein, can also add 0～30 milliliter in the described modulation concentrated solution again.

The present invention also provides a kind of preparation method for the treatment of the pill of hepatitis A, hepatitis B disease and chronic hepatitis disease, it is characterized in that the method comprising the steps of:

1) the Chinese medicine mixing development with following weight portion prescription is powder, and 1 part of Radix Pseudostellariae, 1 part of the distant five tastes, 1 part of Radix Et Rhizoma Rhei, 1 part of Rhizoma Paridis, 1 part of the Radix Paeoniae Alba, 0.75 part in Alumen, 1 part of Radix Curcumae, 2 parts of flaggers are made standby Chinese medicine mixed-powder;

2) Chinese medicine with following weight portion prescription mixes fried one-tenth concentrated solution, 2 parts of Herba Hyperici Japonici, 2 parts of Rhizoma Polygoni Cuspidati, 2 parts of Herba Sedis, 1 part of Cornu Bubali slice, 1 part of Radix Sophorae Flavescentis, 1 part of Ganoderma, 1 part of Herba Artemisiae Scopariae, the mixture of raw material decocts with water twice more than each kilogram, each amount of water was not advisable to have powder, merge decocting liquid twice, filtration and heating concentrate makes 300～500 milliliters modulation concentrated solution;

3) with above-mentioned steps 2) the modulation concentrated solution made modulation above-mentioned steps 1) prepared standby Chinese medicine mixed-powder, the modulation concentrated solution that the adding of the standby Chinese medicine mixed-powder of each kilogram raw material is 300～500 milliliters evenly mixes, and makes the wet pill of 6～10 ball/grams;

4) will wet pill oven dry is the finished product pill, and its baking temperature is 70～75 ℃, and stoving time is 1～3 hour.

Wherein, in step 2) can also add 0～30 milliliter Mel in the described modulation concentrated solution.

The present invention sums up on the basis of secret prescription handed down in the family from generation to generation the inventor, again in conjunction with he or she's clinical experience for a long time, pill of the treatment hepatitis A that is provided, hepatitis B disease and chronic hepatitis disease and preparation method thereof, being used for the treatment of chronic type b chronic persistent hepatitis or active hepatitis transaminase raises, and jaundice is not moved back for a long time, tangible curative effect is arranged, cholecystitis and cholelithiasis are also had curative effect preferably.This medicine adopts the processing of pure natural Chinese herbal medicine to concoct, wherein enzyme falls in Radix Pseudostellariae, Fructus Schisandrae Chinensis supplementing QI and nourishing YIN, Radix Et Rhizoma Rhei blood circulation promoting and blood stasis dispelling, promoting the function of the gallbladder to alleviate jaundice, Radix Sophorae Flavescentis, Rhizoma Paridis heat-clearing and toxic substances removing, dampness, all medicines gather supplementing QI and nourishing YIN, heat clearing away altogether and fall enzyme, promoting the function of the gallbladder to alleviate jaundice, removing blood stasis with potent drugs Sal Nitri, removing dampness antidotal effect.Clinical observation shows, symptoms of digestive tract such as that this medicine can improve significantly is nauseating, anorexia, and transaminase lowering has certain jaundice eliminating effect, and onset is very fast, low price, the patient who is fit to vast rural area and low-income group uses.

The specific embodiment

Below by introducing embodiment and case in detail, further specify the specific embodiment of the present invention and effect.

Embodiment 1

Embodiments of the invention 1 provide a kind of pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease, and the weight portion prescription of its raw material is:

The mix powder of raw material adds 300 milliliters modulation concentrated solution more than each kilogram, is modulated to the pill of 6～10 ball/grams.

The mixture of raw material adds decocting system, filters, is condensed into 300 milliliters modulation concentrated solution more than each kilogram.

Wherein, the Mel that adds 30 milliliters in the described modulation concentrated solution again.

For making the pill of above-mentioned treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, the present invention also provides the preparation method of this pill, and the method comprising the steps of:

2) Chinese medicine with following weight portion prescription mixes fried one-tenth concentrated solution, 2 parts of Herba Hyperici Japonici, 2 parts of Rhizoma Polygoni Cuspidati, 2 parts of Herba Sedis, 1 part of Cornu Bubali slice, 1 part of Radix Sophorae Flavescentis, 1 part of Ganoderma, 1 part of Herba Artemisiae Scopariae, the mixture of raw material decocts with water twice more than each kilogram, each amount of water was not advisable to have powder, merge decocting liquid twice, filtration and heating concentrate makes 300 milliliters modulation concentrated solution;

3) with above-mentioned steps 2) the modulation concentrated solution made modulation above-mentioned steps 1) prepared standby Chinese medicine mixed-powder, the standby Chinese medicine mixed-powder of each kilogram raw material adds 300 milliliters modulation concentrated solution and 30 milliliters Mel, evenly mix, and make the wet pill of 6～10 ball/grams;

4) will wet pill oven dry is the finished product pill, and its baking temperature is 70～75 ℃, and stoving time is 1.5 hours.

Embodiment 2

Embodiments of the invention 2 provide a kind of pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease, and the weight portion prescription of its raw material is:

The mix powder of raw material adds 400 milliliters modulation concentrated solution more than each kilogram, is modulated to the pill of 6～10 ball/grams.

The mixture of raw material adds decocting system, filters, is condensed into 400 milliliters modulation concentrated solution more than each kilogram.

Wherein, the Mel that adds 10 milliliters in the described modulation concentrated solution again.

2) Chinese medicine with following weight portion prescription mixes fried one-tenth concentrated solution, 2 parts of Herba Hyperici Japonici, 2 parts of Rhizoma Polygoni Cuspidati, 2 parts of Herba Sedis, 1 part of Cornu Bubali slice, 1 part of Radix Sophorae Flavescentis, 1 part of Ganoderma, 1 part of Herba Artemisiae Scopariae, the mixture of raw material decocts with water twice more than each kilogram, each amount of water was not advisable to have powder, merge decocting liquid twice, filtration and heating concentrate makes 400 milliliters modulation concentrated solution;

3) with above-mentioned steps 2) the modulation concentrated solution made modulation above-mentioned steps 1) prepared standby Chinese medicine mixed-powder, the standby Chinese medicine mixed-powder of each kilogram raw material adds 400 milliliters modulation concentrated solution and 10 milliliters Mel, evenly mix, and make the wet pill of 6～10 ball/grams;

4) will wet pill oven dry is the finished product pill, and its baking temperature is 70～75 ℃, and stoving time is 2.0 hours.

Embodiment 3

The prescription of the pill prescription of embodiment 3 and modulation concentrated solution is identical with embodiment 1 and 2, and just modulation concentrated solution wherein is concentrated into 350 milliliters, and adds 20 milliliters Mel.Its preparation method also correspondingly changes in step 2) in, heating concentrates and makes 350 milliliters modulation concentrated solution, in step 3), adds 350 milliliters modulation concentrated solution and 20 milliliters Mel in the standby Chinese medicine mixed-powder of each kilogram raw material.In described scope, do suitably to change as for the variation of baking temperature and time in visual season and weather, to dry degree of being.Other guide repeats no more.

Embodiment 4

The prescription of the pill prescription of embodiment 4 and modulation concentrated solution is identical with embodiment 1 and 2, and just modulation concentrated solution wherein is concentrated into 500 milliliters, wherein no longer adds Mel.Its preparation method also correspondingly changes in step 2) in, heating concentrates and makes 500 milliliters modulation concentrated solution, wherein no longer adds Mel, in step 3), adds 500 milliliters modulation concentrated solution in the standby Chinese medicine mixed-powder of each kilogram raw material.In described scope, do suitably to change as for the variation of baking temperature and time in visual season and weather, to dry degree of being.Other guide repeats no more.

The pill of the treatment hepatitis A that the inventor once made with above-mentioned manufacture method, hepatitis B disease and chronic hepatitis disease is treated a large amount of hepatitis patients, obtains tangible curative effect, and the patient is reflected well.The panel of expert that China Association of Traditional Chinese Medicine in 2002 forms once in the Yongcheng City, Henan and the surrounding area many cases are carried out on-the-spot investigation by the patient of inventor's treatment, in order to further specify effect of the present invention, again the clinical observation on the therapeutic effect for the treatment of 11 model cases of Type B viral hepatitis with the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease is described in detail below:

Investigate purpose: observe clinical efficacy with the pill treatment Type B viral hepatitis of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease.

Investigation method: the method that adopts own control, perspective study.

Result: with pill treatment Type B viral hepatitis 11 examples of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, the effect of all improve significantly symptom of digestive tract, transaminase lowering, and the patient carried out following up a case by regular visits to half a year, do not see obviously repeatedly stable curative effect.

Data and the method investigated:

1, case source: Yongcheng City, Henan Province Bai Yang neighbourhood committee spring thatched cottage outpatient service and entrust the expert of China Association of Traditional Chinese Medicine to observe case totally 11 examples, 14 years old of age minimum maximum 50 years old, average 34.6 years old, is the male.Acute hepatitis 2 examples wherein, chronic active hepatitis 5 examples, chronic persistent hepatitis 4 examples merge cirrhotic ascites, splenomegaly person's 2 examples, jaundice person's 1 example.The course of disease is the longest 11 years, the shortest 1 month.

2, diagnostic criteria: meet the diagnostic criteria of the hepatitis B that the national viral hepatitis meeting of nineteen ninety the 6th time of holding in Shanghai of Chinese Medical Association formulates.

3, observational technique: (1) method of administration: adult every day 2 times, each 4～6 grams (10 ball/gram); 10～15 year old every day 2 times, each 2～4 grams, 6～10 years old every day 2 times, each 1～3 gram.Warm water delivery service after the supper early.(2) course of treatment: chronic type b delay property or active hepatitis, transaminase raise, jaundice is not moved back 30 days courses of treatment of person for a long time, can recover normally two to three courses of treatment of heavier individually patient a general course of treatment.

Investigate institute's accepted standard and result:

1, criterion of therapeutical effect:

Efficacy assessment standard according to internal medicine hepatopathy Professional Committee of China Association of Traditional Chinese Medicine Dalian meeting (in August, 1993) formulation.

Clinical cure: symptom all disappears, and repeatedly checks liver function (transaminase, turbidity etc.) and recovers normal, does not have recurrence in half a year.

Produce effects: symptomatology is eliminated, and the transaminase raises once in a while, and is no repeatedly big in half a year.

Take a turn for the better: cardinal symptom is eliminated substantially, low person when high during the transaminase.

Invalid: doing well,improving is not obvious, does not reach effective standard, very person deterioration person.

2, result:

(1) clinical cure 8 examples, produce effects 2 examples, invalid 1 example.Wherein 1 routine nonresponder is that the course of disease is longer, and outbreak is associated with cirrhotic ascites, splenomegaly patient repeatedly.

(2) physico-chemical examination is influenced: hepatitis B two double inspection great three positive positive person 6 examples before the treatment, small three positive positive person 5 examples.Treatment back great three positive transfers the small three positive to person's 2 examples, person's 1 example of all not turning out cloudy.

Liver function is improved: glutamate pyruvate transaminase (ALT) soprano 1226u, the lowest 87u; Glutamic oxaloacetic transaminase, GOT (AST) soprano 380u, the lowest 86u; Transpeptidase (r-GT) soprano 197u, the lowest 76u.ALT, AST all transfer normal person's 9 examples to, descender's 1 example, no significant change person's 1 example in the treatment back.

All patient B-ultrasound investigation shows that all liver increases, 5cm under the maximum rib, minimum 1.5cm.Treatment back 9 people's livers retraction recovers normal, 2 people's no changes.

The transaminase generally began to descend in the back of taking medicine in 2 weeks, and it is apparent in view to descend in 1 month, recovered normal person's 5 examples in 2 months; Recovered normal person's 4 examples in 3-4 month; Recovered normal person's 1 example in 6 months; Wherein 1 example is obeyed no significant change in 4 months and is stopped using.

The shortest 1 month of medicine time, the longest took medicine 8 months.Follow up a case by regular visits to half a year after withdrawing medicine, recurrence does not all appear in the patient of all alleviations.

List 11 model cases being investigated below,, further specify curative effect to make comparisons.

Typical case's case history 1

Patient's name: Cui Kai man 31 years old

Unit: Yongcheng City, Henan Province family members institute of construction bureau

The main suit: abdominal distention, hepatic region are not easypro, weak, poor appetite, yellow urine.

History of present illness: this patient in August calendar year 2001 because of abdominal distention, weak yellow urine and be diagnosed as hepatitis B to the public examination in hospital result that treats, hospitalization is basic complete, disease relapse after several months, to spring thatched cottage diagnosis and treatment, take pill treatment secondary every day of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, each 40 to 60, after one month, the state of an illness takes a favorable turn, after obeyed continuously 4 months, subjective symptoms is good, recovered normally not have repeatedly so far through the check liver function.

The present invention treats the pill treatment toxicity b hepatitis clinical observation of hepatitis A, hepatitis B disease and chronic hepatitis disease

Physical data
Physical data							Name	Cui Kai		Sex	The man		Age	31 years old
Occupation	The worker of construction bureau		The native place	Yongcheng City, Henan Province family members institute of construction bureau			Name	Cui Kai		Sex	The man		Age	31 years old
Occupation	The worker of construction bureau		The native place				Main suit: chronic viral hepatitis B, abdominal distention, poor appetite, weak, yellow urine
History of present illness: once cured in hospital after the patient is diagnosed as hepatitis B August calendar year 2001, after again the recurrence, cure to spring thatched cottage LC, clothes treatment hepatitis A, pill secondary every day of hepatitis B disease and chronic hepatitis disease, each 40-60 grain, 4 months symptoms of taking medicine altogether are basic complete, chemically examine every index and all recover normal.
							Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result	Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result	Abdominal distention		TB25			Abdominal distention disappears		TB15
Weak, poor appetite urine xanthochromia		DB6			Appetite is promoted clear urine in large amounts and is recovered work	DB3	Abdominal distention		TB25			Abdominal distention disappears		TB15
		DB6				DB3	ALT1328			ALT40 unit
		HBSAG (+)				HBSAG (+)	ALT1328			ALT40 unit

Typical case's case history 2

Patient's name: Li Peng man 14 years old

Unit: Lane 18, people road, Yongcheng City, Henan Province

Main suit: little Huang of urinating, poor appetite, weak.

History of present illness: this patient is a hepatitis B in school census, because mental tension causes poor appetite, weak, little Huang of urinating, take several hepatitis B medicine unsatisfactory curative effects, went to spring thatched cottage LC diagnosis and treatment afterwards, the pill of taking treatment hepatitis A, hepatitis B disease and chronic hepatitis disease after one month subjective symptoms take a turn for the better, after to look into liver function normal.Continued to take medicine HBGAG all transference cures of turning out cloudy 4 months.

Physical data
Physical data								Name	Li Peng		Sex	The man		Age		14 years old
Occupation	The student		The native place	Lane 18, people road, Yongcheng City, Henan Province				Name	Li Peng		Sex	The man		Age		14 years old
Occupation	The student		The native place	Lane 18, people road, Yongcheng City, Henan Province				Main suit: during school census, find hepatitis B (virus carrier)
History of present illness: generally investigate to behind the B-mode liver, take several hepatitis B medicine unsatisfactory curative effects, the spring thatched cottage LC diagnosis and treatment of coming May 18, take the pill 30 days of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, look into liver function and take a turn for the better, continue and obeyed this medicine 30 days.July 31 after the drug withdrawal, look into the normal great three positive HBeAg of liver function and turn out cloudy, after continue drug withdrawal in two months again, now conscious good.
								Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result		Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result		Mental tension do not feel like a meal urine little Huang		GOT73.48U/I			The optimistic appetite of spirit is normal		Liver function is normal
GOT49.11U/I										GOT73.48U/I					Liver function is normal
GOT49.11U/I					The great three positive HbeAg positive		Great three positive HBeAg turns out cloudy

Typical case's case history 3

Patient's name: Liu Huai mountain man 34 years old

Unit: Gao Zhuan town, Yongcheng City, Henan Province

The main suit: poor appetite, weak, detest oil, yellow urine.

History of present illness: 5 years causes are weak, and poor appetite, stomach discomfort be to city's examination in hospital hepatitis B two half, great three positive.Take several hepatitis B medicines, unsatisfactory curative effect, the spring thatched cottage diagnosis and treatment of coming, take the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, treat 30 days subjective symptomss and well continued to obey four months, look into two and half every indexs normally, the HBSAG positive only, the desire food is normal, weak disappearance, clear urine in large amounts, only HBSAG is positive several times in the back check.

Physical data
Physical data							Name	Liu Huaishan		Sex	The man		Age		34 years old
Occupation	The cadre of country government		The native place	Gao Zhuan town, Yongcheng City, Henan Province			Name	Liu Huaishan		Sex	The man		Age		34 years old
Occupation	The cadre of country government		The native place	Gao Zhuan town, Yongcheng City, Henan Province			The main suit: poor appetite, weak, anorexia is greasy, urine is yellow sometimes.
History of present illness: cause was weak in 5 years, abdominal discomfort, detest oil, look into hepatitis B two and half and be great three positive, once took several hepatitis B medicine poor effect, the pill of hepatitis A, hepatitis B disease and chronic hepatitis disease is treated in spring in March, 2003 thatched cottage diagnosis and treatment.Take a month subjective symptoms and take a turn for the better, continued clothes four months, look into hepatitis B two and half, great three positive, binomial is turned out cloudy, only the HBSAGB positive.
							Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result	Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result	Poor appetite		GOT73.48U/I			Appetite is normal		HBSAG (+)
Weakly detest oil urine xanthochromia		GOT49.11U/I			The optimistic clear urine in large amounts of spirit	HBGAG (-)	Poor appetite		GOT73.48U/I			Appetite is normal		HBSAG (+)
		GOT49.11U/I				HBGAG (-)	The HBSAG positive			Anti--HBC (-)

Typical case's case history 4

Patient's name: Wang Liang man 24 years old

Unit: Dong Daying village, Yongcheng City, Henan Province

Main suit: hyperpyrexia, uncomfortable in chest, poor appetite.

History of present illness: this patient is because of hyperpyrexia, the thatched cottage diagnosis and treatment of next spring, occurs uncomfortable in chestly after two days, and vomiting, urine xanthochromia are looked into liver function TBN 30u/L, TTT 20 units, ALT 560 units, AST 336 units through Dongguan, the Yongcheng City Second Academy.The thatched cottage diagnosis and treatment of next spring, according to symptomatic diagnosis is Fiedeler's disease type hepatitis, take the treatment hepatitis A, hepatitis B disease and chronic hepatitis disease pill, every day secondary, each 60 (6 grams) obeyed 15 days continuously, the seven days patient's transference cures of infusing, clear urine in large amounts, appetite is promoted, clinical basic complete, the patient be reluctant the treatment, after look into TBN6u/L10 unit, ACT60 unit, AST54 unit.

Physical data
Physical data							Name	Wang Liang	Sex	The man		Age	24 years old
Occupation	Unemployed	The native place	Dong Daying village, Yongcheng City, Henan Province				Name	Wang Liang	Sex	The man		Age	24 years old
Occupation	Unemployed	The native place	Dong Daying village, Yongcheng City, Henan Province				Main suit: hyperpyrexia, poor appetite, weak, urine xanthochromia.
History of present illness: this patient's May is because of hyperpyrexia, yellow sclera after I infused two days, uncomfortable in chest, the abdominal distention vomiting, to the check result Tbu of the Dongguan Second Academy 30, TTT 20 units, ALT 560 units, AST 336 units, be diagnosed as acute icterohepatitis, the thatched cottage treatment of next spring, infused seven days, take the treatment hepatitis A, the pill of hepatitis B disease and chronic hepatitis disease 15 days, clinical basic healing, appetite is weak, just yellow the disappearance.
							Before the treatment				After the treatment
Symptom		Check result		Symptom		Check result	Before the treatment				After the treatment
Symptom		Check result		Symptom		Check result	Hyperpyrexia, weak abdominal distention, uncomfortable in chest, vomiting yellow urine		TBU 30u/L		The normal stomach of body temperature is received fragrant clear urine in large amounts		TBU6V/L
TTT 20 units		TTT10 unit							TBU 30u/L				TBU6V/L
TTT 20 units		TTT10 unit	ALT 560 units		LCT60 unit
AST 334 units		AST54	ALT 560 units		LCT60 unit

Typical case's case history 5

Patient's name: contain and join the army male 28 years old

Unit: Yongcheng City, Henan Province Xincheng District building constructor

Main suit: detest oil, myasthenia of limbs, lassitude.

History of present illness: the patient in calendar year 2001 JIUYUE because of detesting oil, weak to examination in hospital, be diagnosed as hepatitis B through chemical examination, the thatched cottage diagnosis and treatment of spring in October.Look into 3CM under the liver rib, ACT 636, and AGGT 208.Take the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, each 60 of every day three times (6 gram), subjective symptoms is good after one month, and the half a year of taking medicine continuously is many, and liver function recovery is normal, and hepatomegaly can not be touched.Clinical cure is until not recurrence today.

The pill that the present invention treats hepatitis A, hepatitis B disease and the chronic hepatitis disease viral hepatitis b clinical observation of curing the disease

Physical data
Physical data						Name	Sheng is joined the army		Sex	The man	Age		28 years old
Occupation	The worker		The native place	Yongcheng City, Henan Province Xincheng District building constructor		Name	Sheng is joined the army		Sex	The man	Age		28 years old
Occupation	The worker		The native place			Main suit: detest oil, limbs fatigue, lassitude.
History of present illness: the patient in calendar year 2001 JIUYUE because of detesting oil, weak to the chemical examination of public treatment examination in hospital, be diagnosed as hepatitis B, October 26 was come the diagnosis and treatment of grass hall, looked into 3CM ACT 636 AGGT 208 under the liver rib.Take the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, every day secondary, each 60, after one month, subjective symptoms is good, liver function recovery is normal after obeying half a year continuously, originally hepatomegaly 3CM, rehabilitation.						Main suit: detest oil, limbs fatigue, lassitude.
						Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Detest oily limbs fatigue lassitude		ALT 636a		The normal energetic stomach of diet is received fragrant clear urine in large amounts		ACT is normal
GGT 208a		AST 40a						ALT 636a				ACT is normal
GGT 208a		AST 40a

Typical case's case history 6

Patient's name: Liu Ke gift man 30 years old

Unit: four groups in Dong Daying village, Yongcheng City, Henan Province

The main suit: weak, yellowish urine, the hepatic region is little painful, stomach upset.

History of present illness: the original b hepatitis of this patient, in city's hospitalize more than a year, in JIUYUE, 2003 is checked liver function ACT230u as a result, AST 190u, to spring thatched cottage diagnosis and treatment, take the treatment hepatitis A, hepatitis B disease and chronic hepatitis disease pill, every day secondary, each 50 (5 gram) clothes after one month subjective symptoms better, diet increases, and the hepatic region stomach is pain no longer, takes a favorable turn through looking into liver function, be thorough healing, patient requires to obey 2 months again.

Physical data
Physical data						Name	Liu Keli		Sex	The man	Age		30 years old
Occupation	The driver		The native place	Dong Daying village, Yongcheng City, Henan Province		Name	Liu Keli		Sex	The man	Age		30 years old
Occupation	The driver		The native place	Dong Daying village, Yongcheng City, Henan Province		The main suit: weak, yellowish urine, the hepatic region is painful, stomach upset.
History of present illness: the original chronic hepatitis B of patient, check liver function ACT 230u after 1 year, AST 190u, to spring thatched cottage diagnosis and treatment, take the treatment hepatitis A, the pill of hepatitis B disease and chronic hepatitis disease, every day secondary, each 50 (5 gram) clothes after one month subjective symptoms better, diet increases, liver painful, is not looked into liver function and recovers normal substantially.
						Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Weak, yellowish urine liver aches, poor appetite		ALT 230u		Spirit takes a turn for the better, and diet increases, and it is clear long that urine becomes		GOT 51.47 ua/L
AST 190u		GPT 98.49 ua/L						ALT 230u				GOT 51.47 ua/L
AST 190u		GPT 98.49 ua/L

Typical case's case history 7

Patient's name: Jiang Hua man 30 years old

Unit: Lane three, Bai Yang residential district, Yongcheng City, Henan Province

Main suit: suffer from hepatitis B for many years, limbs fatigue, stomach discomfort.

History of present illness: the original hepatitis B of this patient, through western medicines in treatment, fail to cure, in April, 2002, due to illness feelings are exacerbated to spring thatched cottage diagnosis and treatment, through looking into 1.5cm under conscience (-) the liver rib, low grade fever, yellowish urine are diagnosed as chronic hepatitis B, treatment: the pill of clothes treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, each 60 of secondary every day (6 gram) early, boiled water takes after the supper, treat the improvement of month patient's spirit, and health check-up is normal, appetite increases, the check liver function is normal substantially, obeys again by last dosage that to look into liver function in 2 months all normal, clinical cure.

Physical data
Physical data						Name	Jiang Hua		Sex	The man	Age		30 years old
Occupation	The worker of power plant		The native place	Lane three, Bai Yang residential district, Yongcheng City, Henan Province		Name	Jiang Hua		Sex	The man	Age		30 years old
Occupation	The worker of power plant		The native place			Main suit: limbs fatigue, little Huang of urinating, stomach discomfort
History of present illness: suffered from hepatitis B 3 years, through the Chinese and Western hospitalize, poor effect, check liver function ALT 724 units in April, 2002 through Yongcheng City coal hospital general, AST 381 units, to spring thatched cottage outpatient service diagnosis and treatment, through looking into 1.5cm under cardiopulmonary () the liver rib, the low grade fever yellowish urine is diagnosed as chronic hepatitis B.Take the pill three months of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, the patient gets well, and it is normal to look into liver function, clinical cure.
						Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Limbs fatigue, urine xanthochromia, stomach discomfort		ALT 724		Appetite increases, clear urine in large amounts, antisecosis		ALT 27.6ua/L
AST 381		AST 26.14ua/L						ALT 724				ALT 27.6ua/L
AST 381		AST 26.14ua/L

Typical case's case history 8

Patient's name: old closing bright male 42 years old

Unit: Mi Lou village, Liu He township, Yongcheng City, Henan Province

The main suit: abdominal distention, poor appetite, weak, yellowish urine.

History of present illness: the patient in May because of abdominal distention, poor appetite, weak to the city public examination in hospital, ALT 456 units treated, AST 105u V-GT 155u, and hepatitis B two half HBSAg (+) check to spring thatched cottage diagnosis and treatment, 2.6cm under the liver rib, and 2cm is diagnosed as chronic hepatitis B under the spleen rib.Treatment: take the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, every day twice, each 60 (6) gram serve on three months liver functions and subjective symptoms and takes a favorable turn, and it is normal substantially to reexamine liver function.

Physical data
Physical data								Name	Chen Heming		Sex	The man		Age		42 years old
Occupation	The peasant		The native place	Mi Lou village, Liu He township, Yongcheng City, Henan Province				Name	Chen Heming		Sex	The man		Age		42 years old
Occupation	The peasant		The native place					Main suit: abdominal distention, poor appetite, weak, yellowish urine.
History of present illness: the patient in May because of abdominal distention, poor appetite, weak to the public examination in hospital liver function for the treatment of, ALT 456 units, AST 105u V-GT 155u, hepatitis B two and half HBSAg (+), the back is to spring thatched cottage diagnosis and treatment, check 2.6cm under the liver rib, 2em under the spleen rib, take the treatment hepatitis A, the pill of hepatitis B disease and chronic hepatitis disease, twice of every day, each 60 (6) gram, it is normal substantially to serve on three months liver functions.
								Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result		Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result		Abdominal distention, poor appetite, weak, yellowish urine		ALT 456 units			Abdominal distention disappears, and diet is promoted, clear urine in large amounts		TB 13ua/L
HBSAg (+)			DB 4ua/L							ALT 456 units					TB 13ua/L
HBSAg (+)			DB 4ua/L		AST 105u		ACT 45ua/L
V-GT 155u			AST64ua/L		AST 105u		ACT 45ua/L
V-GT 155u			AST64ua/L				V-GT197ua/L
			The AFD positive				V-GT197ua/L

Typical case's case history 9

Patient's name: king's filial piety friend man 47 years old

Unit: four groups in Dong Daying village, Yongcheng City, Henan Province

The main suit: limbs fatigue, poor appetite, rib is painful, little Huang of urinating.

History of present illness: the patient is in February, 2003, because of weak, stomach upset, poor appetite; little Huang of urinating is checked to the Second Academy; the back is checked to the spring thatched cottage; take the treatment hepatitis A; the pill of the sick and chronic hepatitis disease of hepatitis B; every day secondary, each 40-60 (10 1 grams) obeyed three months continuously, subjective symptoms is good; drug withdrawal; do not look into liver function, behind the some months because of overworking and feel that the hepatic region is painful, stomach discomfort; inappetence; look into liver function ALT 265, AST 176 units continue clothes treatment hepatitis A; the pill of hepatitis B disease and chronic hepatitis disease one month; dosing is the same, it is normal substantially that November 1 was checked function.

The viral hepatitis b clinical observation of curing the disease of yellow enzyme liver poison clearing pellet

Physical data
Physical data						Name	Wang Xiaoyou		Sex	The man	Age		47 years old
Occupation	The peasant		The native place	Four groups in Dong Daying village, Yongcheng City, Henan Province		Name	Wang Xiaoyou		Sex	The man	Age		47 years old
Occupation	The peasant		The native place			The main suit: poor appetite, weak, stomach do not relax, little Huang of urinating.
History of present illness: the original hepatitis B of this patient, through each tame hospitalize, the time light when heavy.February is to the Second Academy, look into liver function, ACT 374 units, AST 296 units, afterwards to spring thatched cottage diagnosis and treatment, take the treatment hepatitis A, the pill of hepatitis B disease and chronic hepatitis disease, every day secondary, each 40-60 (10 1 grams) obeyed three months continuously, subjective symptoms is good, behind the drug withdrawal some months, because of the hepatopathy recurrence of overworking, continue to take the treatment hepatitis A, the pill of hepatitis B disease and chronic hepatitis disease is normal substantially by the check in month of preceding dosing.
						Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Limbs fatigue stomach discomfort yellowish urine		ALT 374 units		Diet normal hepatocytes functional rehabilitation		TBLL 4ua/L
AST296		TTT 8 units						ALT 374 units				TBLL 4ua/L
AST296		TTT 8 units			ALT 60 units
		AST 90 units			ALT 60 units

Typical case's case history 10

Patient's name: Jiang Wei man 29 years old

Unit: No. 345, mountain gate facing the street board in the Yongcheng City, Henan Province

The main suit: the hepatic region does not relax, and poor appetite is weak, yellowish urine.

History of present illness: the patient suffers from Fiedeler's disease type hepatitis the year before, more the back is because of drinking too much, and liver function TBH 30ua/L, ALT 625 units are looked in the hepatopathy recurrence, AST 136 units, to spring thatched cottage diagnosis and treatment, looked into 3cm under the liver rib afterwards, abdominal distention is weak, yellowish urine, anorexia, take the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease, every day secondary, each 60 (6 gram), taking medicine added transfusion seven days in 30 days.Look into liver function again: TBH 19.8ua/L, TTT 3 units, ALT52 unit, AST 38 units, HbeAg turns out cloudy.Clinical cure.

Physical data
Physical data						Name	Jiang Wei		Sex	The man	Age		29 years old
Occupation	The electrician		The native place	No. 345, mountain gate facing the street board in the Yongcheng City, Henan Province		Name	Jiang Wei		Sex	The man	Age		29 years old
Occupation	The electrician		The native place			Main suit: poor appetite, weak, yellowish urine.
History of present illness: the patient checked to the Second Academy because of the flu yellowish urine in October, 2002, hepatitis B two and half, be Fiedeler's disease type hepatitis, after more leaving hospital 1 year entirely, hospitalization recurs because of the too much hepatopathy of drinking, look into liver function TBH 30ua/L, ALT 625 units, AST 136 units, afterwards to spring thatched cottage diagnosis and treatment, take the treatment hepatitis A, the pill of hepatitis B disease and chronic hepatitis disease, every day secondary, each 60 (6 gram), infused seven days, the check liver function is every normal, and HbeAg turns out cloudy.						Main suit: poor appetite, weak, yellowish urine.
						Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Before the treatment				After the treatment
Symptom		Check result		Symptom	Check result	Poor appetite, weak, yellowish urine		TBH 30ua/L		Diet is promoted, clear urine in large amounts, weak disappearance.		TBLL 19.8ua/L
TTT 3 units		TTT 3 units						TBH 30ua/L				TBLL 19.8ua/L
TTT 3 units		TTT 3 units		AST 136	ALT 52 units
		AST 38 units		AST 136	ALT 52 units

Typical case's case history 11

Patient's name: Sun Xin field man 30 years old

Unit: the king village, Xiao Xian Zhang Wangzhai township, Anhui Province

Main suit: abdominal distention, poor appetite, little Huang of urinating.

History of present illness: this patient infuses in township hospital because of heating, abdominal distention appears after several days, epistaxis; yellow urine; to township examination in hospital liver function ALT 152 units, anti--the HBL positive, it is smooth that Glisson's capsule is owed; rib 3cm under the spleen; upon somebody's introduction, to spring thatched cottage LC portion treatment, is diagnosed as cirrhotic ascites; take the pill of treatment hepatitis A, hepatitis B disease and chronic hepatitis disease; add decoction WUPI YIN, tympanites ball, and abdominal distention disappears after two months, and liver function is normal; continue treatment and check the high disappearance of spleen, clinical cure after 6 months.

Physical data
Physical data							Name	Sun Xintian		Sex	The man		Age	30 years old
Occupation	Be engaged in agriculture		The native place	The king village, Xiao Xian Zhang Wangzhai township, Anhui Province			Name	Sun Xintian		Sex	The man		Age	30 years old
Occupation	Be engaged in agriculture		The native place				Main suit: chronic hepatopathy, liver cirrhosis, ascites, cholecystitis.
History of present illness: this patient is because of generating heat at township hospital hospitalization, infuse and abdominal distention occurs after several days, epistaxis, hydrops in the ultrasound diagnosis abdomen; urine xanthochromia; the type body is become thin; after coal hospital general in Yongcheng City checks;; the pill of hepatitis B disease and chronic hepatitis disease; add two months ascites of WUPI YIN treatment and disappear, liver function recovery is normal to spring thatched cottage LC portion diagnosis and treatment; take the treatment hepatitis A.
							Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result	Before the treatment					After the treatment
Symptom		Check result			Symptom	Check result	Abdominal distention, poor appetite, urine xanthochromia, low grade fever		ALT 152 units			Abdominal distention disappears, clear urine in large amounts, and appetite increases.			Liver function
AST 276			SGPT is normal						ALT 152 units						Liver function
AST 276			SGPT is normal	ALT/AST 1.82
Bilirubin 648				ALT/AST 1.82
Bilirubin 648				Albumen is inverted

Claims

1. a pill for the treatment of hepatitis A, hepatitis B disease and chronic hepatitis disease is characterized in that, the weight portion prescription of its raw material is:

2. the pill of treatment hepatitis A according to claim 1, hepatitis B disease and chronic hepatitis disease, wherein, the parts by weight of raw materials prescription of described modulation concentrated solution is:

3. the pill of treatment hepatitis A according to claim 1, hepatitis B disease and chronic hepatitis disease wherein, adds 0～30 milliliter Mel again in the described modulation concentrated solution.

4. preparation method for the treatment of the pill of hepatitis A, hepatitis B disease and chronic hepatitis disease is characterized in that the method comprising the steps of:

5. the preparation method of the pill of treatment hepatitis A according to claim 4, hepatitis B disease and chronic hepatitis disease is wherein, in step 2) add 0～30 milliliter Mel in the described modulation concentrated solution.