CN1742941A - External medicine formulation for treating anhypnia-depression and technology for making plaster using same - Google Patents

External medicine formulation for treating anhypnia-depression and technology for making plaster using same Download PDF

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CN1742941A
CN1742941A CNA2005101054584A CN200510105458A CN1742941A CN 1742941 A CN1742941 A CN 1742941A CN A2005101054584 A CNA2005101054584 A CN A2005101054584A CN 200510105458 A CN200510105458 A CN 200510105458A CN 1742941 A CN1742941 A CN 1742941A
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polygoni multiflori
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CN100349603C (en
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徐涛
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Abstract

The present invention discloses a prescription of medicine for external application for curing insomnic depression with obvious therapeutic effect. Said prescription is formed from 30 Chinese medicinal materials of cinnabar, epimedium, musk, silk tree bark, bamboo sugar, acanthopanax root bark, bovine bezoar and others.

Description

The Recipe of external-use medicine of Cure for insomnia depression and the technology of making plaster with this prescription
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Recipe of external-use medicine of Cure for insomnia depression and with this prescription made plaster.
Background technology
In modern society, because rhythm of life is accelerated, people work under secular pressure environment, be easy to produce deeply worried, worried emotion, this emotion further develops the insomnia that will cause the people, melancholy, thereby dreaminess, absent minded, the auditory hallucination hallucination, vexed uneasiness, irritability, give free rein to fancy and produce plant function and wad a quilt with cotton disorderly, seriously influence people's work and life, at present generally by taking oral medicine, and at present used Western medicine is generally relatively good at the use initial stage to this treatment for doctor trained in Western medicine, in use for some time, effect is not very desirable just, and is easy to generate side effect.
Summary of the invention
Shortcoming at above-mentioned prior art exists the object of the present invention is to provide a kind of Chinese medicine preparation of using, and is effective, the Recipe of external-use medicine of Cure for insomnia depression easy to use and the technology of making plaster with this prescription.
The technical solution used in the present invention is: a kind of prescription of medicine for external use of Cure for insomnia depression, and it is made up of following medicine, and the weight quota of every kind of medicine is respectively: Cinnabaris 1-5 part; Herba Epimedii 1-2 part; Moschus 0.01-0.02 part; Cortex Albiziae 2-4 part; Concretio Silicea Bambusae 2-8 part; South Acanthopanax gracilistylus 2-4 part; Calculus Bovis 1.1-1.4 part; Caulis Polygoni Multiflori 1.5-2 part; Haematitum 2-5 part; Radix Rehmanniae 1-2 part; Cornu Saigae Tataricae powder 0.12-0.18 part; Poria cum Radix Pini 0.5-4 part; Gypsum Fibrosum 2-6 part; Radix Astragali 0.5-2 part; Concha Margaritifera 3-8 part; Semen Platycladi 1-2 part; Radix Salviae Miltiorrhizae 2-4 part; Five Fructus Armeniacae Mume 0.5-2 parts; Semen Ziziphi Spinosae 4-8 part; Flos Lilii viriduli 0.5-2 part; Radix Codonopsis 2-4 part; Magnetitum 4-8 part; Radix Angelicae Sinensis 2-4 part; Succinum 0.5-1 part; Radix Polygoni Multiflori Preparata 0.5-2 part; Borneolum Syntheticum 0.1-0.4; Arillus Longan 0.5-2 part; Rhizoma Acori Graminei 1-2 part; Radix Polygalae 1.5-4 part; Fructus Forsythiae 0.5-1 part.
The prescription of the medicine for external use of described Cure for insomnia depression, the weight quota of every kind of medicine is respectively: 5 parts in Cinnabaris; 2 parts of Herba Epimedii; 0.02 part in Moschus; 4 parts of Cortex Albiziaes; 8 parts of Concretio Silicea Bambusaes; 4 parts of south Acanthopanax gracilistylus; 1.4 parts of Calculus Boviss; 2 parts of Caulis Polygoni Multiflori; 5 parts of Haematitums; 2 parts in the Radix Rehmanniae; 0.18 part of Cornu Saigae Tataricae powder; 4 parts of Poria cum Radix Pinis; 6 parts in Gypsum Fibrosum; 2 parts of the Radixs Astragali; 8 parts of Concha Margaritiferas; 2 parts of Semen Platycladi; 4 parts of Radix Salviae Miltiorrhizaes; 2 parts in five Fructus Armeniacae Mumes; 8 parts of Semen Ziziphi Spinosaes; 2 parts of Flos Lilii viridulies; 4 parts of Radix Codonopsis; 8 parts of Magnetitums; 4 parts of Radix Angelicae Sinensis; 1 part of succinum; 2 parts of Radix Polygoni Multiflori Preparata; Borneolum Syntheticum 0.4; 2 parts of Arillus Longans; 2 parts of Rhizoma Acori Graminei; 4 parts of Radix Polygalaes; 1 part of Fructus Forsythiae.
According to the processing technology that the prescription of the medicine for external use of Cure for insomnia depression is made the external plaster of Cure for insomnia depression, it comprises the steps:
(1) pulverizes:, pulverize separately respectively and sieving for standby Concha Margaritifera, Cinnabaris, Magnetitum, Calculus Bovis, Moschus, Cornu Saigae Tataricae powder, Haematitum, Gypsum Fibrosum, succinum, Arillus Longan, the Borneolum Syntheticum of above-mentioned share.
(2) extract: place the extraction still to add water boiling and extraction Radix Salviae Miltiorrhizae, Radix Polygalae, Rhizoma Acori Graminei, south Acanthopanax gracilistylus, Poria cum Radix Pini, five Fructus Armeniacae Mumes, Fructus Forsythiae, Flos Lilii viriduli, Herba Epimedii, Cortex Albiziae, Caulis Polygoni Multiflori, the Radix Rehmanniae, the Radix Astragali, Semen Platycladi, Semen Ziziphi Spinosae, Radix Codonopsis, Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, the Concretio Silicea Bambusae of cleaning, separation and Extraction liquid, pressure filtration, filtrate for later use.
(3) concentrate: step (2) gained filtrate is placed in the concentrator, and the decompression heating concentrates, and obtains concentrated extract.
(4) mix: the medicated powder that step (1) is obtained stays the powder of Borneolum Syntheticum that half is standby, and other mixes with extractum that step (3) obtains, and carries out drying then, and pulverizing adds remaining Borneolum Syntheticum again and makes medicated powder.
(5) make plaster: step (4) gained medicated powder is packed in the bubble paper bag as medicated core, add the non-woven fabrics posting in time and make plaster.
The processing technology of the external plaster of described making Cure for insomnia depression, in step (2) extraction step, extract at twice, extract for the first time: place the extraction still to add 10 times of water gagings Radix Salviae Miltiorrhizae, Radix Polygalae, Rhizoma Acori Graminei, south Acanthopanax gracilistylus, Poria cum Radix Pini, five Fructus Armeniacae Mumes, Fructus Forsythiae, Flos Lilii viriduli, Herba Epimedii, Cortex Albiziae, Caulis Polygoni Multiflori, the Radix Rehmanniae, the Radix Astragali, Semen Platycladi, Semen Ziziphi Spinosae, Radix Codonopsis, Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, the Concretio Silicea Bambusae of cleaning and extract, heating decocts extracted 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use; Extract for the second time, toward extracting the water that adds 5 times of amounts in the still, heating decocts extracted 1 hour, separation and Extraction liquid, and pressure filtration merges twice filtrate.
The processing technology of the external plaster of described making Cure for insomnia depression in step (3) concentration step, for negative 200mmHg, is heated to 80 ℃ with filtrate decompression, is concentrated into relative density 1.16-1.18.
The processing technology of the external plaster of described making Cure for insomnia depression, in step (4) blend step, carrying out exsiccant temperature is 50 ℃, pulverizes 100 mesh sieves and becomes fine powder.
The medicine for external use of Cure for insomnia depression of the present invention is by adopting traditional rare Chinese medicine, condensed cream, be applied to umbilical part, because umbilical part sensitivity height, the drug effect penetration is strong, absorb soon, can excite QI of channels and collaterals, play dredging the meridian, QI and blood regulating, adjust the equilibrium between yin and yang of internal organs, thereby reach the effect of Cure for insomnia depression, the present invention is easy to use, do not have toxic and side effects, satisfy people's needs.
The present invention is described in further detail below in conjunction with specific embodiment.
The specific embodiment
Embodiment one
(1) pulverize: 3 parts of Concha Margaritiferas, 1 part in Cinnabaris, 4 parts of Magnetitums, 1.1 parts of Calculus Boviss, 0.01 part in Moschus, 0.12 part of Cornu Saigae Tataricae powder, 2 parts of Haematitums, 2 parts in Gypsum Fibrosum, 0.5 part of succinum, 0.5 part of Arillus Longan, 0.1 part of Borneolum Syntheticum, pulverize separately respectively and to cross 100 mesh sieves standby.
(2) extract: extract at twice, placing the extraction still to add 10 times of water gagings for 2 parts 0.5 part of 2 parts of 1 part of 1.5 parts of 2 parts of Radix Salviae Miltiorrhizaes, Radix Polygalaes, Rhizoma Acori Graminei, south Acanthopanax gracilistylus, Poria cum Radix Pini, 0.5 part in five Fructus Armeniacae Mumes, 0.5 part of Fructus Forsythiae, 0.5 part of Flos Lilii viriduli, 1 part of Herba Epimedii, 2 parts of Cortex Albiziaes, 1.5 parts of Caulis Polygoni Multiflori, 1 part in the Radix Rehmanniae, 0.5 part of the Radix Astragali, 1 part of Semen Platycladi, 4 parts of Semen Ziziphi Spinosaes, 2 parts of Radix Codonopsis, 2 parts of Radix Angelicae Sinensis, 0.5 part of Radix Polygoni Multiflori Preparata, the Concretio Silicea Bambusae of cleaning for the first time extracts, heating decocts extracted 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use; Extract for the second time, toward extracting the water that adds 5 times of amounts in the still, heating decocts extracted 1 hour, separation and Extraction liquid, and pressure filtration merges twice filtrate.
(3) concentrate: step (2) gained filtrate is placed in the concentrator, filtrate decompression for negative 200mmHg, is heated to 80 ℃, be concentrated into relative density 1.16-1.18, obtain concentrated extract.
(4) mix: the medicated powder that step (1) is obtained stays the powder of Borneolum Syntheticum that half is standby, and other and extractum mixing granulation of step (3) acquisition place 50 ℃ of freeze-day with constant temperature, pulverize 100 mesh sieves and become fine powder, add remaining Borneolum Syntheticum again and make medicated powder.
(5) make plaster: step (4) gained medicated powder is packed in the bubble paper bag as medicated core, add the non-woven fabrics posting in time and make plaster, can open medicated powder according to 3g/ and pack in 3.5cm * 5.2cm bag bubble paper bag, add non-woven fabrics posting in time packing and get final product as medicated core.
Embodiment two
(1) pulverize: 8 parts of Concha Margaritiferas, 5 parts in Cinnabaris, 8 parts of Magnetitums, 1.4 parts of Calculus Boviss, 0.02 part in Moschus, 0.18 part of Cornu Saigae Tataricae powder, 5 parts of Haematitums, 6 parts in Gypsum Fibrosum, 1 part of succinum, 2 parts of Arillus Longans, 0.4 part of Borneolum Syntheticum, pulverize separately respectively and to cross 100 mesh sieves standby.
(2) extract: extract at twice, placing the extraction still to add 10 times of water gagings for 8 parts 4 parts of 4 parts of 2 parts of 4 parts of 4 parts of Radix Salviae Miltiorrhizaes, Radix Polygalaes, Rhizoma Acori Graminei, south Acanthopanax gracilistylus, Poria cum Radix Pinis, 2 parts in five Fructus Armeniacae Mumes, 1 part of Fructus Forsythiae, 2 parts of Flos Lilii viridulies, 2 parts of Herba Epimedii, 4 parts of Cortex Albiziaes, 2 parts of Caulis Polygoni Multiflori, 2 parts in the Radix Rehmanniae, 2 parts of the Radixs Astragali, 2 parts of Semen Platycladi, 8 parts of Semen Ziziphi Spinosaes, 4 parts of Radix Codonopsis, 4 parts of Radix Angelicae Sinensis, 2 parts of Radix Polygoni Multiflori Preparata, the Concretio Silicea Bambusae of cleaning for the first time extracts, heating decocts extracted 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use; Extract for the second time, toward extracting the water that adds 5 times of amounts in the still, heating decocts extracted 1 hour, separation and Extraction liquid, and pressure filtration merges twice filtrate.
(3) concentrate: step (2) gained filtrate is placed in the concentrator, filtrate decompression for negative 200mmHg, is heated to 80 ℃, be concentrated into relative density 1.16-1.18, obtain concentrated extract.
(4) mix: the medicated powder that step (1) is obtained stays the powder of Borneolum Syntheticum that half is standby, and other and extractum mixing granulation of step (3) acquisition place 50 ℃ of freeze-day with constant temperature, pulverize 100 mesh sieves and become fine powder, add remaining Borneolum Syntheticum again and make medicated powder.
(5) make plaster: step (4) gained medicated powder is packed in the bubble paper bag as medicated core, add the non-woven fabrics posting in time and make plaster, can open medicated powder according to 3g/ and pack in 3.5cm * 5.2cm bag bubble paper bag, add non-woven fabrics posting in time packing and get final product as medicated core.
In order to make better effects if of the present invention, Cinnabaris can select Zhu's emery, Radix Salviae Miltiorrhizae to select for use Radix Salviae Miltiorrhizae, the Radix Rehmanniae to select for use the Huaihe River Radix Rehmanniae, Radix Codonopsis to select Radix codonopsis pilosulae (Radix Codonopsis) for use, and in order to reduce cost, Calculus Bovis can be selected the artificial Calculus Bovis for use certainly.
The present invention cooperatively interacts by taking multidigit Chinese medicine, and by the mode Cure for insomnia depression of external application, clinical trial is generally applied ointment or plaster and taken effect in 1-7 days, and 7 days is a course of treatment, 1-3 the rehabilitation course of treatment, has no side effect, easy to use.

Claims (6)

1, a kind of prescription of medicine for external use of Cure for insomnia depression is characterized in that: it is made up of following medicine, and the weight quota of every kind of medicine is respectively: Cinnabaris 1-5 part; Herba Epimedii 1-2 part; Moschus 0.01-0.02 part; Cortex Albiziae 2-4 part; Concretio Silicea Bambusae 2-8 part; South Acanthopanax gracilistylus 2-4 part; Calculus Bovis 1.1-1.4 part; Caulis Polygoni Multiflori 1.5-2 part; Haematitum 2-5 part; Radix Rehmanniae 1-2 part; Cornu Saigae Tataricae powder 0.12-0.18 part; Poria cum Radix Pini 0.5-4 part; Gypsum Fibrosum 2-6 part; Radix Astragali 0.5-2 part; Concha Margaritifera 3-8 part; Semen Platycladi 1-2 part; Radix Salviae Miltiorrhizae 2-4 part; Five Fructus Armeniacae Mume 0.5-2 parts; Semen Ziziphi Spinosae 4-8 part; Flos Lilii viriduli 0.5-2 part; Radix Codonopsis 2-4 part; Magnetitum 4-8 part; Radix Angelicae Sinensis 2-4 part; Succinum 0.5-1 part; Radix Polygoni Multiflori Preparata 0.5-2 part; Borneolum Syntheticum 0.1-0.4; Arillus Longan 0.5-2 part; Rhizoma Acori Graminei 1-2 part; Radix Polygalae 1.5-4 part; Fructus Forsythiae 0.5-1 part.
2, the prescription of the medicine for external use of Cure for insomnia depression according to claim 1 is characterized in that: the weight quota of every kind of medicine is respectively: 5 parts in Cinnabaris; 2 parts of Herba Epimedii; 0.02 part in Moschus; 4 parts of Cortex Albiziaes; 8 parts of Concretio Silicea Bambusaes; 4 parts of south Acanthopanax gracilistylus; 1.4 parts of Calculus Boviss; 2 parts of Caulis Polygoni Multiflori; 5 parts of Haematitums; 2 parts in the Radix Rehmanniae; 0.18 part of Cornu Saigae Tataricae powder; 4 parts of Poria cum Radix Pinis; 6 parts in Gypsum Fibrosum; 2 parts of the Radixs Astragali; 8 parts of Concha Margaritiferas; 2 parts of Semen Platycladi; 4 parts of Radix Salviae Miltiorrhizaes; 2 parts in five Fructus Armeniacae Mumes; 8 parts of Semen Ziziphi Spinosaes; 2 parts of Flos Lilii viridulies; 4 parts of Radix Codonopsis; 8 parts of Magnetitums; 4 parts of Radix Angelicae Sinensis; 1 part of succinum; 2 parts of Radix Polygoni Multiflori Preparata; Borneolum Syntheticum 0.4; 2 parts of Arillus Longans; 2 parts of Rhizoma Acori Graminei; 4 parts of Radix Polygalaes; 1 part of Fructus Forsythiae.
3, make the processing technology of the external plaster of Cure for insomnia depression according to the prescription of claim 1 or 2, it is characterized in that: it comprises the steps:
(1) pulverizes:, pulverize separately respectively and sieving for standby Concha Margaritifera, Cinnabaris, Magnetitum, Calculus Bovis, Moschus, Cornu Saigae Tataricae powder, Haematitum, Gypsum Fibrosum, succinum, Arillus Longan, the Borneolum Syntheticum of above-mentioned share.
(2) extract: place the extraction still to add water boiling and extraction Radix Salviae Miltiorrhizae, Radix Polygalae, Rhizoma Acori Graminei, south Acanthopanax gracilistylus, Poria cum Radix Pini, five Fructus Armeniacae Mumes, Fructus Forsythiae, Flos Lilii viriduli, Herba Epimedii, Cortex Albiziae, Caulis Polygoni Multiflori, the Radix Rehmanniae, the Radix Astragali, Semen Platycladi, Semen Ziziphi Spinosae, Radix Codonopsis, Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, the Concretio Silicea Bambusae of cleaning, separation and Extraction liquid, pressure filtration, filtrate for later use.
(3) concentrate: step (2) gained filtrate is placed in the concentrator, and the decompression heating concentrates, and obtains concentrated extract.
(4) mix: the medicated powder that step (1) is obtained stays the powder of Borneolum Syntheticum that half is standby, and other mixes with extractum that step (3) obtains, and carries out drying then, and pulverizing adds remaining Borneolum Syntheticum again and makes medicated powder.
(5) make plaster: step (4) gained medicated powder is packed in the bubble paper bag as medicated core, add the non-woven fabrics posting in time and make plaster.
4, the processing technology of the external plaster of making Cure for insomnia depression according to claim 3, it is characterized in that: in step (2) extraction step, extract at twice, extract for the first time: place the extraction still to add 10 times of water gagings Radix Salviae Miltiorrhizae, Radix Polygalae, Rhizoma Acori Graminei, south Acanthopanax gracilistylus, Poria cum Radix Pini, five Fructus Armeniacae Mumes, Fructus Forsythiae, Flos Lilii viriduli, Herba Epimedii, Cortex Albiziae, Caulis Polygoni Multiflori, the Radix Rehmanniae, the Radix Astragali, Semen Platycladi, Semen Ziziphi Spinosae, Radix Codonopsis, Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, the Concretio Silicea Bambusae of cleaning and extract, heating decocts extracted 2 hours, separation and Extraction liquid, pressure filtration, filtrate for later use; Extract for the second time, toward extracting the water that adds 5 times of amounts in the still, heating decocts extracted 1 hour, separation and Extraction liquid, and pressure filtration merges twice filtrate.
5, according to the processing technology of the external plaster of claim 3 or 4 described making Cure for insomnia depressions, it is characterized in that: in step (3) concentration step, filtrate decompression for negative 200mmHg, is heated to 80 ℃, is concentrated into relative density 1.16-1.18.
6, the processing technology of the external plaster of making Cure for insomnia depression according to claim 5 is characterized in that: in step (4) blend step, carrying out exsiccant temperature is 50 ℃, pulverizes 100 mesh sieves and becomes fine powder.
CNB2005101054584A 2005-09-28 2005-09-28 External medicine formulation for treating anhypnia-depression and technology for making plaster using same Expired - Fee Related CN100349603C (en)

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CN101961436A (en) * 2010-09-14 2011-02-02 广东养美医药投资有限公司 Bath effervescent tablets for improving sleep
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CN102327336A (en) * 2011-09-19 2012-01-25 徐柔云 External sleeping patch
CN102973682A (en) * 2011-09-06 2013-03-20 徐柔云 Long time effective technology for treatment of insomnia
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CN100460007C (en) * 2006-11-07 2009-02-11 杨永信 A Medicine for treatment of netting addiction
CN101019980B (en) * 2007-03-28 2010-05-19 北京艺信堂医药研究所 Health product for improving sleep quality
CN101518575B (en) * 2008-02-27 2011-05-25 北京绿源求证科技发展有限责任公司 Traditional Chinese medicine for treating diabetic insomnia
CN101961436A (en) * 2010-09-14 2011-02-02 广东养美医药投资有限公司 Bath effervescent tablets for improving sleep
CN101961436B (en) * 2010-09-14 2011-11-30 广东养美医药投资有限公司 Bath effervescent tablets for improving sleep
CN102225186A (en) * 2011-06-27 2011-10-26 史建钢 Medicine for treating neurosis and preparation method thereof
CN102973682A (en) * 2011-09-06 2013-03-20 徐柔云 Long time effective technology for treatment of insomnia
CN102327336A (en) * 2011-09-19 2012-01-25 徐柔云 External sleeping patch
CN102327336B (en) * 2011-09-19 2013-01-16 宁波浙成科技咨询有限公司 External sleeping patch
CN103505521A (en) * 2013-01-09 2014-01-15 席安胜 Formula of plaster for treating insomnia
CN104784458A (en) * 2015-04-26 2015-07-22 李厚建 Traditional Chinese medicine composition for treating insomnia
CN105168703A (en) * 2015-08-28 2015-12-23 江苏七O七天然制药有限公司 Traditional Chinese medicine gel plaster applied to acupoints to treat insomnia and preparation method thereof
CN106902190A (en) * 2017-03-22 2017-06-30 杨文婷 A kind of Chinese medicine patcher formula for treating insomnia and preparation method thereof
CN110592805A (en) * 2019-08-31 2019-12-20 福建恒安集团有限公司 Preparation method and application of lily tuber fleeceflower stem sleep-aiding non-woven fabric
CN110592805B (en) * 2019-08-31 2021-06-15 福建恒安集团有限公司 Preparation method and application of lily tuber fleeceflower stem sleep-aiding non-woven fabric

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