CN1733132A - Chinese traditional medicine preparation capable of reducing fever, resolving phlegm, ventilating and smoothing a troubled lung and relieving cough and process for preparing the same - Google Patents
Chinese traditional medicine preparation capable of reducing fever, resolving phlegm, ventilating and smoothing a troubled lung and relieving cough and process for preparing the same Download PDFInfo
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- CN1733132A CN1733132A CN 200510031940 CN200510031940A CN1733132A CN 1733132 A CN1733132 A CN 1733132A CN 200510031940 CN200510031940 CN 200510031940 CN 200510031940 A CN200510031940 A CN 200510031940A CN 1733132 A CN1733132 A CN 1733132A
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Abstract
The invention relates to a heat-clearing, phlegm-resolving and cough-releaving Chinese medicinal composition and process for preparation, which is prepared mainly from Chinese herbs including cordate houttuynia, cymose buckwheat rhizome, Chinese ilex leaf, Chinese ephedra, aster, peucedanum root, bitter orange and licorice root.
Description
Technical field:
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, relate in particular to Chinese medicine preparation of a kind of removing heat-phlegm lung qi dispersing cough-relieving and preparation method thereof.
Background technology:
Drop pill in the Chinese medicine preparation or buccal tablet or soft capsule, change dosage form and manage as new drug research according to the relevant laws and regulations of China's drug control as a kind of pharmaceutical dosage form.The existing dosage form of this product is a granule, has listed the national drug standards in.
The technology features of the Chinese medicine preparation particles for acute bronchitis of existing removing heat-phlegm lung qi dispersing cough-relieving is to get Herba Houttuyniae, Fructus Aurantii extraction volatile oil, and the aqueous solution after the distillation filters, and other collects by device respectively for filtrate and volatile oil, Six-elements such as all the other Rhizoma Fagopyri Dibotryiss decoct with water, and collecting decoction filters, filtrate and above-mentioned aqueous solution merge, and are concentrated into into thick paste, are dried to fine powder, mixing, add suspensoid and adjuvant, make granule, drying, add above-mentioned volatile oil, mixing makes granule;
Inconvenience is carried, is taken in the Chinese medicine preparation particles for acute bronchitis existence of existing removing heat-phlegm lung qi dispersing cough-relieving, needs shortcomings such as boiled water is taken after mixing it with water, dose big, difficult preservation.
Summary of the invention:
The purpose of this invention is to provide Chinese medicine preparation of a kind of removing heat-phlegm lung qi dispersing cough-relieving and preparation method thereof, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
The objective of the invention is to be achieved through the following technical solutions.
The Chinese medicine preparation of removing heat-phlegm lung qi dispersing cough-relieving, it is that main component is drop pill or buccal tablet or the soft capsule of Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae, Radix Asteris, Radix Peucedani, Fructus Aurantii, Radix Glycyrrhizae.
Its preparation method is:
(1) medicine constituent and percentage by weight thereof are as follows:
Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims each 20～30%, Herba Ephedrae 3～7%, Radix Asteris 8～15%, Radix Peucedani, Fructus Aurantii each 5～10%, Radix Glycyrrhizae 1～5%;
The optimum weight percentage ratio of main constituent is:
Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims each 22.7%, Herba Ephedrae 4.6%, Radix Asteris 11.4%, Radix Peucedani, Fructus Aurantii each 6.8%, Radix Glycyrrhizae 2.3%.
(2) Herba Houttuyniae, Fructus Aurantii add water distillation and extraction volatile oil, and be standby; Aqueous solution after distillation device is in addition collected, and is standby;
(3) Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae, Radix Asteris, Radix Peucedani, Radix Glycyrrhizae decoct with water 1～3 time, and each 1～3 hour, collecting decoction filtered, aqueous solution after the distillation of filtrate and (2) gained merges, and is concentrated into thick paste, is dried and crushed into fine powder, mixing gets fine drug powder, and is standby;
(4) get the mixed powder of (3) gained, after adding suitable adjuvant, the volatile oil that adds (2) gained, one or more or other suitable adjuvant with stearic acid or glyceryl monostearate or insect wax or Cera Flava or Polyethylene Glycol (PEG4000 or PEG6000) or sodium stearate or glycerin gelatine or polyoxyethylene monostearate (S-40) or Poloxamer188, use with by arbitrary proportion, add in the said medicine after being heated to whole fusions, be transferred in the liquid containing bottle rapidly after stirring, airtight and the insulation at 70～100 ℃, under heat-retaining condition, go in the liquid coolant (liquid paraffin or methyl-silicone oil or vegetable oil or water or ethanol) by dropping-pill machine, condensation cured becomes ball, with the drop pill drop of molding to the greatest extent and remove coolant, dry coationg promptly;
(5) preparation method of its buccal tablet is: get the fine drug powder of (3) gained, add appropriate amount of auxiliary materials, and mix homogeneously, drying, the volatile oil of adding (2) gained is pressed into buccal tablet;
Adjuvant is one or more mixture or other suitable adjuvant in the following material, uses with by arbitrary proportion:
Icing Sugar, lactose, mannitol, dextrin, aspartame, stevioside, starch, mucialga of arabic gummy, gelatine size, Mentholum (Herba Menthae essence), Borneolum Syntheticum, citric acid;
(6) get (3) gained fine drug powder, add appropriate amount of auxiliary materials, mix homogeneously, the volatile oil of adding (2) gained is suppressed or is dripped and makes soft capsule;
Adjuvant is one or more mixture or other suitable adjuvant in the following material, uses with by arbitrary proportion:
PEG400, vegetable oil, aromatic hydrocarbon esters, glycerol, isopropyl alcohol, tween;
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
The Chinese medicine preparation of a kind of removing heat-phlegm lung qi dispersing cough-relieving, it is that main component is drop pill or buccal tablet or the soft capsule of Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae, Radix Asteris, Radix Peucedani, Fructus Aurantii, Radix Glycyrrhizae.
Chinese medicine preparation energy removing heat-phlegm of the present invention, the lung qi dispersing cough-relieving.Be mainly used in the cough due to the affection due to external wind and heat, disease is seen heating, aversion to cold, full vexed, the cough pharyngalgia of chest and diaphragm; Above-mentioned patient is seen in acute bronchitis, acute episode of chronic bronchitis.
The preparation method of Chinese medicine preparation of the present invention is:
(1) medicine constituent and weight consumption thereof are as follows:
Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, each 900g of Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae 180g, Radix Asteris 450g, Radix Peucedani, each 270g of Fructus Aurantii, Radix Glycyrrhizae 90g;
(2) Herba Houttuyniae, Fructus Aurantii add water distillation and extraction volatile oil, and be standby; Aqueous solution after distillation device is in addition collected, and is standby;
(3) Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae, Radix Asteris, Radix Peucedani, Radix Glycyrrhizae decoct with water 3 times, and each 1 hour, collecting decoction filtered, and the aqueous solution after the distillation of filtrate and (2) gained merges, and is concentrated into thick paste, is dried and crushed into fine powder, and mixing gets mixed powder; Standby;
(4) the Chinese medicine preparation drop pill of removing heat-phlegm lung qi dispersing cough-relieving is an acute bronchitis drip pill, its preparation method is: the fine drug powder of getting (3) gained, after adding suitable adjuvant, the volatile oil that adds (2) gained, taking polyethylene glycol PEG6000 100g, stearic acid 40g, Poloxamer188 20g, treat Polyethylene Glycol PEG6000, stearic acid, Poloxamer188 adds in the said medicine after being heated to whole fusions, be transferred in the liquid containing bottle rapidly after stirring, airtight and the insulation at 80 ℃, at heat-retaining condition by splashing in the liquid paraffin, be condensed into ball, with the drop pill drop of molding to the greatest extent and the erasing liquor paraffin body, cold drying promptly.
(5) the Chinese medicine preparation buccal tablet of transconversion into heat expectorant lung qi dispersing cough-relieving is an anxious buccal tablet, its preparation method is: the hybrid medicine of getting (4) gained, add cane sugar powder 100g, abundant mixing, cross 60～80 mesh sieves, add the Herba Menthae essence of 50g starch and 10ml, granulation, granulate, oven dry simultaneously with the 30g mucialga of arabic gummy, add the volatile oil of (2) gained, be pressed into buccal tablet.
(7) the Chinese medicine preparation soft capsule of removing heat-phlegm lung qi dispersing cough-relieving is an anxious soft capsule, its preparation method is to get (4) gained hybrid medicine, behind water dissolution, the adding adjuvant is the combination of one or more different proportions in PEG400, vegetable oil, aromatic hydrocarbon esters, glycerol, isopropyl alcohol, the tween, the volatile oil that adds (2) gained is suppressed or is dripped and makes soft capsule.
Advantage of the present invention is:
Carry, taking convenience, dose is few, rapid-action, bioavilability is high, controllability and good stability, have Be beneficial to the raising curative effect.
Claims (3)
1, the Chinese medicine preparation of a kind of removing heat-phlegm lung qi dispersing cough-relieving is characterized in that it is that main component is acute bronchitis drip pill or buccal tablet or the soft capsule of Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae, Radix Asteris, Radix Peucedani, Fructus Aurantii, Radix Glycyrrhizae.
2, the preparation method of the Chinese medicine preparation of a kind of removing heat-phlegm lung qi dispersing cough-relieving, it is acute bronchitis drip pill or buccal tablet or preparation of soft capsule method, it is characterized in that:
(1) medicine constituent and percentage by weight thereof are as follows:
Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims each 20～30%, Herba Ephedrae 3～7%, Radix Asteris 8～15%, Radix Peucedani, Fructus Aurantii each 5～10%, Radix Glycyrrhizae 1～5%;
(2) Herba Houttuyniae, Fructus Aurantii add water distillation and extraction volatile oil, and be standby; Aqueous solution after distillation device is in addition collected, and is standby;
(3) Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims, Herba Ephedrae, Radix Asteris, Radix Peucedani, Radix Glycyrrhizae decoct with water 1～3 time, and each 1～3 hour, collecting decoction filtered, aqueous solution after the distillation of filtrate and (2) gained merges, and is concentrated into thick paste, is dried and crushed into fine powder, mixing gets fine drug powder, and is standby;
(4) get the fine drug powder of (3) gained, add suitable adjuvant after, add the volatile oil of (2) gained, hybrid medicine, be made into drop pill or buccal tablet or soft capsule;
The preparation method of its drop pill is: with one or more or other suitable adjuvant of stearic acid or glyceryl monostearate or insect wax or Cera Flava or Polyethylene Glycol (PEG4000 or PEG6000) or sodium stearate or glycerin gelatine or polyoxyethylene monostearate (S-40) or Poloxamer188, use with by arbitrary proportion, be heated to the hybrid medicine that adds (4) gained after whole fusions, be transferred in the liquid containing bottle rapidly after stirring, airtight and the insulation at 70～100 ℃, under heat-retaining condition, go in the liquid coolant (liquid paraffin or methyl-silicone oil or vegetable oil or water or ethanol) by dropping-pill machine, condensation cured becomes ball, with the drop pill drop of molding to the greatest extent and remove coolant, dry coationg promptly;
The preparation method of its buccal tablet is: gets the fine drug powder of (3) gained, adds appropriate amount of auxiliary materials, and mix homogeneously, drying, the volatile oil of adding (2) gained is pressed into buccal tablet;
Adjuvant is one or more mixture or other suitable adjuvant in the following material, uses with by arbitrary proportion:
Icing Sugar, lactose, mannitol, dextrin, aspartame, stevioside, starch, mucialga of arabic gummy, gelatine size, Mentholum (Herba Menthae essence), Borneolum Syntheticum, citric acid;
Its preparation of soft capsule method is: gets (3) gained fine drug powder, adds appropriate amount of auxiliary materials, and mix homogeneously, the volatile oil of adding (2) gained is suppressed or is dripped and makes soft capsule;
Adjuvant is one or more mixture or other suitable adjuvant in the following material, uses with by arbitrary proportion:
PEG400, vegetable oil, aromatic hydrocarbon esters, glycerol, isopropyl alcohol, tween.
3, the preparation method of the Chinese medicine preparation of a kind of removing heat-phlegm lung qi dispersing according to claim 2 cough-relieving is characterized in that the optimum weight percentage ratio of its main constituent is:
Herba Houttuyniae, Rhizoma Fagopyri Dibotryis, Ilex purpurea Hassk.[I.chinensis Sims each 22.7%, Herba Ephedrae 4.6%, Radix Asteris 11.4%, Radix Peucedani, Fructus Aurantii each 6.8%, Radix Glycyrrhizae 2.3%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510031940 CN1733132A (en) | 2005-07-29 | 2005-07-29 | Chinese traditional medicine preparation capable of reducing fever, resolving phlegm, ventilating and smoothing a troubled lung and relieving cough and process for preparing the same |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104983968A (en) * | 2015-06-10 | 2015-10-21 | 山西省中医药研究院 | Pyretolysis traditional Chinese medicine composition and preparation method |
| CN105801639A (en) * | 2016-03-23 | 2016-07-27 | 卞毓平 | Method for extracting stevioside from stevia rebaudiana and stevioside product |
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2005
- 2005-07-29 CN CN 200510031940 patent/CN1733132A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104983968A (en) * | 2015-06-10 | 2015-10-21 | 山西省中医药研究院 | Pyretolysis traditional Chinese medicine composition and preparation method |
| CN105801639A (en) * | 2016-03-23 | 2016-07-27 | 卞毓平 | Method for extracting stevioside from stevia rebaudiana and stevioside product |
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