CN1733016A - 一种清热解毒泡腾片及其制备方法 - Google Patents
一种清热解毒泡腾片及其制备方法 Download PDFInfo
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- CN1733016A CN1733016A CN 200510098722 CN200510098722A CN1733016A CN 1733016 A CN1733016 A CN 1733016A CN 200510098722 CN200510098722 CN 200510098722 CN 200510098722 A CN200510098722 A CN 200510098722A CN 1733016 A CN1733016 A CN 1733016A
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配方号 | 药粉(g) | 酸种类(g) | 碱种类(g) | 结果 |
1 | 14 | 酒石酸14 | 碳酸氢钠14 | 制粒、压片、泡腾均好 |
2 | 14 | 己二酸14 | 碳酸氢钠14 | 泡腾太慢,效果不好 |
3 | 14 | 丁二酸14 | 碳酸氢钠14 | 吸潮,无法制粒 |
4 | 14 | 苹果酸14 | 碳酸氢钠14 | 吸潮,无法制粒 |
5 | 14 | 富马酸14 | 碳酸氢钠14 | 较好,泡腾慢 |
6 | 14 | 柠檬酸14 | 碳酸氢钠14 | 结块,无法制粒 |
序号 | 药粉占片重比例 | 泡腾剂占片重比例 | 酸占泡腾剂比例 | 泡腾效果 | 崩解时间(分) |
11 | 1/3 | 2/3 | 40% | +++ | 1分 |
2 | 1/3 | 2/3 | 45% | ++++ | 1.1 |
3 | 1/3 | 2/3 | 50% | ++++ | 1.2 |
4 | 1/3 | 2/3 | 55% | +++ | 2.1 |
5 | 2/5 | 3/5 | 40% | +++ | 4.4 |
6 | 2/5 | 3/5 | 45% | +++ | 4.4 |
7 | 2/5 | 3/5 | 50% | +++ | 4.6 |
8 | 2/5 | 3/5 | 55% | +++ | 4.7 |
9 | 1/2 | 1/2 | 40% | ++ | 超出限时 |
10 | 1/2 | 1/2 | 45% | ++ | 超出限时 |
11 | 1/2 | 1/2 | 50% | ++ | 超出限时 |
12 | 1/2 | 1/2 | 55% | ++ | 超出限时 |
13 | 3/5 | 2/5 | 40% | + | 超出限时 |
14 | 3/5 | 2/5 | 45% | + | 超出限时 |
15 | 3/5 | 2/5 | 50% | + | 超出限时 |
16 | 3/5 | 2/5 | 55% | + | 超出限时 |
序号 | 药粉(g) | 酸(g) | 碱(g) | 崩解时间 | 泡腾后药液评价 |
1 | 1.45 | 1.31 | 1.59 | 1分40秒 | 药液有少量絮状物,口感一般。 |
2 | 1.45 | 1.38 | 1.52 | 1分42秒 | 药液有少量絮状物,口感一般。 |
3 | 1.45 | 1.45 | 1.45 | 1分50秒 | 药液澄清,口感好。 |
4 | 1.45 | 1.51 | 1.39 | 1分12秒 | 药液稍混浊,口感一般。 |
样品 | 外观性状 | 泡腾时间 |
试验前 | 棕褐色片剂 | 1分55秒 |
试验后 | 棕褐色片剂 | 1分48秒 |
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB2005100987226A CN1315514C (zh) | 2005-09-07 | 2005-09-07 | 一种清热解毒泡腾片及其制备方法 |
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Application Number | Priority Date | Filing Date | Title |
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CNB2005100987226A CN1315514C (zh) | 2005-09-07 | 2005-09-07 | 一种清热解毒泡腾片及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN1733016A true CN1733016A (zh) | 2006-02-15 |
CN1315514C CN1315514C (zh) | 2007-05-16 |
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Application Number | Title | Priority Date | Filing Date |
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CNB2005100987226A Active CN1315514C (zh) | 2005-09-07 | 2005-09-07 | 一种清热解毒泡腾片及其制备方法 |
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CN (1) | CN1315514C (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102078584A (zh) * | 2010-09-15 | 2011-06-01 | 朱惠芬 | 一种治疗热伤风的中药制剂 |
CN104096204A (zh) * | 2014-07-23 | 2014-10-15 | 重庆大学 | 小儿肺咳泡腾片及其制备方法 |
CN106072565A (zh) * | 2016-07-03 | 2016-11-09 | 陈毅忠 | 一种润肺解毒泡腾片的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1562314A (zh) * | 2004-04-12 | 2005-01-12 | 张正生 | 一种清热解毒泡腾片的制备方法 |
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2005
- 2005-09-07 CN CNB2005100987226A patent/CN1315514C/zh active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102078584A (zh) * | 2010-09-15 | 2011-06-01 | 朱惠芬 | 一种治疗热伤风的中药制剂 |
CN102078584B (zh) * | 2010-09-15 | 2011-11-30 | 姜光红 | 一种治疗热伤风的中药制剂 |
CN104096204A (zh) * | 2014-07-23 | 2014-10-15 | 重庆大学 | 小儿肺咳泡腾片及其制备方法 |
CN104096204B (zh) * | 2014-07-23 | 2017-10-13 | 重庆大学 | 小儿肺咳泡腾片及其制备方法 |
CN106072565A (zh) * | 2016-07-03 | 2016-11-09 | 陈毅忠 | 一种润肺解毒泡腾片的制备方法 |
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Publication number | Publication date |
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CN1315514C (zh) | 2007-05-16 |
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