CN1729861A - Polypeptide food and its production process - Google Patents
Polypeptide food and its production process Download PDFInfo
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- CN1729861A CN1729861A CNA2005100364846A CN200510036484A CN1729861A CN 1729861 A CN1729861 A CN 1729861A CN A2005100364846 A CNA2005100364846 A CN A2005100364846A CN 200510036484 A CN200510036484 A CN 200510036484A CN 1729861 A CN1729861 A CN 1729861A
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Abstract
The invention discloses polypeptide food and its production process, wherein the food is prepared from acidic polypeptide extracted from leeches and other auxiliary materials, including any materials that can be used as foodstuff. The food has the dual functions of adjusting body physiological performance and providing nutrition for the body.
Description
Technical field
The present invention relates to a kind of food, the food that particularly a kind of Acid polypeptide that extracts with hirudinaria manillensis is made.
Background technology
Polypeptide is to be made of amino acid but to be different from the intermediate material of protein, and it has the characteristic of protein, but simpler than protein, molecular weight is little, thereby it is active high, under the situation of trace or low concentration, polypeptide can both be brought into play its unique physiological action.
Polypeptide has following characteristics:
Polypeptide is better than amino acid, and the one, absorb fast than amino acid; The 2nd, absorbed by body with complete form; The 3rd, active absorption (amino acid belongs to passive absorption); The 4th, low consumption is compared with amino acid, and polypeptide absorbs the characteristics that have low consumption or do not require the expenditure of energy, and polypeptide directly enters blood circulation after absorbing by duodenum, and the self-energy nutrient delivery is arrived each position of human body; The 5th, polypeptide absorbs than amino acid, has undersaturated characteristics; The 6th, amino acid has only 20 kinds, and function is denumerable, and polypeptide is substrate with amino acid, can synthesize thousands of up to ten thousand kinds, and function is different.The 7th, running uncontested property and do not have inhibition between each peptide species.
As base nutrients matter, polypeptide is than the easier absorption of amino acid, bioavilability height.Some low molecular peptide class also has diseases prevention simultaneously, cures the disease, and regulates the effect of human body physiological function, and these effects are that crude protein and the amino acid formed thereof are not available.
Acid polypeptide with the hirudinaria manillensis extraction, at normal temperatures and pressures, because its peptide chain is shorter than protein, its stability is more much higher than protein, thereby needn't add just energy long preservation of any stabilizing agent in use, this provides scientific basis for Acid polypeptide is applied on food.
At present, the Application and Development of polypeptide is the heat subject of current bioengineering field, and it is widely used in industries such as medicine, health care, food, cosmetics, is forming the new industry with bright prospects.
Polypeptide is applied to food (health products, nutraceutical, bread and cheese), the Japan that starts from the eighties in last century, and polypeptide food is also in the ascendant in developed countries such as the U.S., West Europe subsequently.Polypeptide food has formed industry at present, and many famous companies become exploitation polypeptide food, the polypeptide food additive of series and add pantry of polypeptide factor or the like.Functional Polypeptides has been widely used in varieties of food items as a kind of high-tech product, in Japan, the U.S. and West Europe, the healthy food that contains polypeptide emerges in an endless stream, and polypeptide beverage, polypeptide children lunch, polypeptide old man set meal, polypeptide motion food are arranged, short calcium absorbing food product, blood pressure-reducing food etc.In China, Wuhan peptide matters research institute has finished serial Chinese medicine polypeptide, the development of tens finished products such as series vegetable polypeptide (comprising soya-bean polypeptides etc.), polypeptide series food additives, polypeptide series flavoring additive and raw meal product has obtained gratifying achievement in the preliminary popularization in market.
We are through retrieval, and the relevant document for preparing active peptides from animal of finding present open source literature report has following:
1, violent [periodical name] food information and technology .2004 (12) .-29-29[digest paid in the research [author] of [autograph] oyster double-enzyme hydrolysis technology] oyster is first in the world cultivated shellfish, also being one of China's four big cultivated shellfishes, is a kind of extremely precious soft-body sea animal.Protein and glycogen content are abundant in the oyster, also are rich in elements such as multivitamin and copper, iron, zinc, iodine, especially contain abundant Taurine, have very high nutritive value.At present, people tend to aminosal to produce active peptide.Enzyme can be hydrolyzed to protein under the condition of gentleness, produces specific peptide.The research work of preparation active peptides also launches from seashells.But,
2, [autograph] progress in Study of Functional Polypeptides [author] is encouraged and is built flat [mechanism] Zhejiang Prov Industrial And Commercial University of flourish envelope food, biological and environmental project institute, [periodical name] Food Science .2004,25 (11) .-415-419[digests] up to now, people have extracted from organisms such as human body, animal, plant and microorganism or have synthesized various peptide materials with physiologically active.This paper has introduced the separate sources and the production method of Functional Polypeptides comparatively all sidedly, has compared excellent, the shortcoming of several production methods commonly used, and has summarized the progress of domestic and international in recent years several critical function peptides.
3, [autograph] utilizes the research [author] of scallop edge manufacturing HAP once to celebrate [1] Ceng Qingxiao [1] Wang Tao [2] Xu Qingling [2] [mechanism] [1] South China Science ﹠ Engineering University's food and bioengineering institute, [2] Dalian aquatic product Academy Department of Food Engineering, [periodical name] South China Science ﹠ Engineering University's journal: natural science edition .2003,31 (8) .-82-87[digests] select for use compound protease enzymolysis scallop edge to prepare hydrolyzate, and optimize the enzymolysis process condition; Adopt hollow fiber ultrafiltration membrane that hydrolyzate is carried out separation and purification, make high-quality HAP, and test membrane separation test operating condition is to the influence of separative efficiency. result of study shows, earlier with subtilopeptidase A enzymolysis 4h, continue enzymolysis with flavor protease then, can significantly improve the content of polypeptide in the enzymolysis liquid, small peptide and free amino acid; Factors such as the pH value of the operating pressure of hyperfiltration, temperature, enzymolysis liquid and cocnentration factor all will influence hyperfiltration efficient, be not higher than 0.10MPa at operating pressure, the pH value is 7.0～7.5, temperature is 43 ℃, just ultrafiltration membrane is carried out under the operating conditions such as backwash of 2min behind every filtration 10min, can improve the service life of the separative efficiency of hyperfiltration, the pollution that reduces film and prolongation film greatly; Result of the test shows that also the organoleptic indicator that hyperfiltration separates posthydrolysis liquid obviously is better than unsegregated hydrolysising original liquid.
4, progress [author] Zhao Rui Gu Qianqun [mechanism] Qingdao Marine University's marine drug and Food Research Inst. of [autograph] natural biological polypeptide, Qingdao [periodical name] research and development of natural products .2000,12 (4) .-84-91[digests] summarized the research recent developments of the active peptides of natural origin in recent years, the research recent developments that mainly stress linear peptides, comprise the people, animal, the extraction separation method of plant origin polypeptide, the progress of aspects such as amino acid composition and biologically active.
5, structure, performance and utilization [author] Chen Hua [1] Hu Guoliang [mechanism] [1] animal science institutes of Zhejiang University such as [2] of [autograph] silk sericin, [2] Zhejiang Prov Engineering Academy, [periodical name] functional polymer journal .2001,14 (3) .-344-348[digests] contain a large amount of sericins in the waste water of silk mill discharging.Sericin is a kind of globular preteins, contain multiple polypeptides, form, contain more serine by 18 kinds of hydrogen base acid, asparatate and glycine, polar side chain amino acid accounts for 74.61%, and sericin has Yi Rong, suction, gelation, correctability and characteristic such as anti-oxidant, at cosmetics, aspects such as food, medicine and biomaterial have excellent development potential.
6, [mechanism] Shandong Light Ind College such as [autograph] Application of Collagen [author] Li Yan spring Cheng Baozhen, [periodical name] leather chemical industry .2002,19 (3) .-10-14[digests] this paper summarized collagen and polypeptide at biology, medical science, food, cosmetics, feed, progress in the industry such as chemicals, along with the performances such as biological function of collagen and collagen polypeptide are familiar with by people gradually, the research of this respect also becomes the focus of research gradually, utilizes the new biological product of animal skins exploitation will improve its added value greatly, has vast potential for future development.
7, the nutrition physiology effect of [autograph] lactoferrin and active peptide thereof and school district, application prospect [author] Luo Xianmei [1] Chen Daiwen [2] Zhang Keying [2] [mechanism] [1] Agricultural University Of Southwest Rongchang County institute of moving section, [2] the feed industry .2005 of Sichuan Agricultural University's Animal nutrition research institute [periodical name], 26 (2) .-5-9[digests] lactoferrin (LF) is a kind of multi-functional glycoprotein, lactoferrin active peptides (Lfein) is a little peptide of going up 25 amino acid residues that got off by pepsin hydrolysis from LF.Set forth the structure of lactoferrin and active peptides thereof in the literary composition, introduced the major physiological effect of lactoferrin and active peptides thereof: antibiotic, antibacterial, antiviral, anti-oxidant, regulate the immunity of body and improve the effects such as absorption of enteron aisle iron ion.According to the progress of lactoferrin preparation, discussed lactoferrin and active peptides thereof in breast, food and animal produce as the Application of Additives prospect.
From above-mentioned literature to, people's life is being come into its application as aspects such as food, medicine, cosmetics in preparation or extract active peptides from animal.But because different animal materials, and the technology that adopts, the polypeptide products that obtains has very big difference.
Show according to relevant scientific research, the low molecular acid polypeptide of forming by a kind of amino acid residue in the class of sucking blood leech (as hiruto, Hirudo japonica, excellent line ox leech, haemadipsa japonica and the Haemadipsa hainana etc.) body (hirudin), it is except the general utility functions with polypeptide, also have anti-freezing and thrombolytic effect, and can bring into play unique effect through blood-brain barrier.Though this Acid polypeptide be it is found that in 1884, the composition and the primary structure of its peptide chain have been confirmed the seventies in eighties of last century, but all the time, the resource of this Acid polypeptide that scientific circles can be extracted by occurring in nature tangible very little wrong viewpoint institute about (really, the leeches that can extract Acid polypeptide in China from hirudinaria manillensis only is distributed in a few provinces and regions such as the Guangdong, Guangxi in south China, its distribution is narrower, and kind and quantity are all limited).This Acid polypeptide (hirudin) is owing to caused great concern at medicine, food, people attempt to adopt artificial synthetic mode to obtain, but, the extractive technique of this Acid polypeptide and production technology did not make a breakthrough all the time, and this is the bottleneck that the restriction Acid polypeptide is produced.
Through arduous exploration for many years; inventor Zhou Weihai has invented in 2003 and carried out repeated multiple times extraction hirudin (Acid polypeptide) technology from the hirudinaria manillensis live body; and declared national inventing patent, application number 03113566, thereby the large-scale production of Acid polypeptide is come true.
The present invention is primary raw material, is aided with the normal food raw material in order to the Acid polypeptide that makes with above-mentioned technology, thereby makes polypeptide food, widened the Another Application field of Acid polypeptide.
Summary of the invention
The purpose of this invention is to provide a kind of polypeptide food, thereby enrich domestic and international polypeptide food kind.
Polypeptide food of the present invention is the Acid polypeptide (being hirudin) that extracts from the class leech of sucking blood (comprising hiruto, Hirudo japonica, excellent line ox leech, haemadipsa japonica and Haemadipsa hainana etc.), its material composition and quality percentage composition following (prescription): Acid polypeptide 0.1～99.9%, auxiliary material 0.1%～99.9%.
Described Acid polypeptide is the low molecular polypeptide that 45-100 amino acid is formed.
Described Acid polypeptide adopts following the extraction or processing technology:
1, the homogenate of live body leech is after centrifugal, ultrafiltration extraction; This method is that the live body class leech of sucking blood is cleaned and to be placed on the beater making beating, uses centrifuge centrifugal then, is the filter membrane filtration of 5000-30000 with the filter below 100 microns or with molecular weight again, puts freezer freezing below 4 ℃.
2, the stem body leech is pulverized back physiological saline lixiviate; This method is that the stem body class leech of sucking blood is pulverized with pulverizer, uses the physiological saline lixiviate again 0.5-5 hour, concentrates and preserves or put freezer freezing below 4 ℃.
3, utilizing induced liquid to stimulate the leech live body that it is salivated, is raw material with these salivas then, extracts through centrifugal, gel chromatography.Chinese patent (application number: method extraction 03113566) according to inventor's application in 2003, specifically be will clean up hiruto with the aqueous solution of acetate, citric acid, sodium chloride, sodium carbonate mixture, its concentration is 0.1%, PH is 4.5, be dissolved in behind the distilled water fully fed to appetite hiruto, then hiruto is pushed and make it secrete saliva (hirudin crude product), and the concentration that adds acid makes the PH of the aqueous solution between 5-6.5.Then to its saliva through centrifugal removal of impurities, separate again and purifying.Separate and purifying is to add 4 times of acetone of moisture 15% of putting precooling in the refrigerator the salivary gland secretion extract that 250-300ml is extracted in above-mentioned hiruto body, stir rearmounted refrigerator overnight, sucking-off supernatant acetone is also centrifugal, the trichloroacetic acid (about 25ml) that adds precooling in precipitation makes its dissolving, the centrifugal residue of removing treats that sample carries out column chromatography.
Anion exchange chromatography is got an amount of DEAE adding distil water and is made its expansion, respectively soaks with 0.5MOL/L NaOH-NaCl mixed liquor, 0.5mol/LHCl and 0.5mol/LNaOH-NaCl mixed liquor successively according to a conventional method to be washed with distilled water to neutrality after 30 minutes.The dress post (2cm * 60cm) to desired height, 0.1mol/L citric acid one sodium citrate buffer solution balance with pH4.6, sample carries out gradient elution and draws elution curve with recorder, the Fractional Collections eluent on the salivary gland secretion concentrate of 5ml or the above-mentioned trichloroacetic acid solution.After testing, will there be vigor partly to concentrate in the bag filter and concentrate, survey total protein content with two methods that contract again, obtain highly purified Acid polypeptide with glycerine.
4, stem body leech ultramicro grinding fine powder; This method is that the stem body class leech of sucking blood is used ultramicro grinding, through directly adding in the food after the sterilization.
The auxiliary material that the present invention is used derives from daily food, comprises following several or combination:
1, edible starch food products comprises cereal starch, potato starch, bean powder, as corn flour, flour, black sesame powder, bean powder, rice meal etc.;
2, meat, egg food, comprise can eat immediately through boiling, steam, bake, fry in shallow oil or the ready-made meat of other processing method, eggs.
3, Western medicine, Chinese medicine or its extract;
4, beverage;
5, the clean water that maybe can drink of pure water.
6, carbohydrate food is as glucose, sucrose, polysaccharide.
Acid polypeptide food making method of the present invention: according to different auxiliary materials, its method for making has following several usually:
When 1, auxiliary material is powdery (as corn flour, flour, Chinese medicine powder, black sesame powder, rice meal etc.), in proportion Acid polypeptide is joined in the powder raw material, stirring, mixing promptly becomes polypeptide powdered food of the present invention.
2, auxiliary material is liquid (as various beverages etc.), in proportion polypeptide is joined mix in the liquid polypeptide liquid food of the present invention.
3, auxiliary material is a cake body shape (as cake, water chestnut cake etc.), in proportion polypeptide is joined mix in the cake body polypeptide cake body food of the present invention.
4, auxiliary material is meat, egg food, edible through boil, steam, bake, fry in shallow oil or the ready-made meat of other processing method in proportion Acid polypeptide is added to mix and obtains.
The preparation method of the above polypeptide food can mix Acid polypeptide and do powdering, solid shape, capsule shape, paste body shape or liquid food with auxiliary material, comprise and make health food, nutraceutical and bread and cheese.
The polypeptide food Quality Control Technology: the active available fibrin ferment titration of Acid polypeptide detects in the polypeptide food, its principle is: Acid polypeptide can combine with the fibrin ferment specificity, make the fibrin ferment inactivation, it is 1: 1 in conjunction with ratio, Acid polypeptide active unit represents with AT-U, the international unit of thrombin activity is NIH, during promptly 1 AT-U equals and the Acid polypeptide amount of 1 NIH fibrin ferment.
Detection method:
Get the about 1g of this product powder (crossing sieve No. three), the accurate title, decide, the accurate 0.9% sodium chloride solution 5ml that adds, fully stir, lixiviate 30 minutes, and jolting constantly, centrifugal, precision is measured supernatant 100 μ l, (among the 10mm * 100ml), the trishydroxymethylaminomethane hydrochloride buffer that adds 0.5% (ox) fibrinogen (in coagulum) (is got 0.2mol/L tris solution 25ml and the about 40ml of 0.1mol/L hydrochloric acid solution, is added water to 100ml to put test tube, regulate pH value to 7.4) 200 μ l, shake up, put slowly drip in the water-bath (37 ℃ ± 0.5 ℃) contain 40 units among every 1ml thrombin solution (per minute 5 μ l shake up gently while dripping) to solidifying, record consumes the volume of thrombin solution, is calculated as follows:
Advantage of the present invention is:
1, the Acid polypeptide (being hirudin) that class leech (comprising hiruto, Hirudo japonica, excellent line ox leech, haemadipsa japonica and Haemadipsa hainana etc.) extracts of will sucking blood, be to constitute by amino acid but be different from the intermediate material of protein, it has the characteristic of protein, but simpler than protein, molecular weight is little, thereby it is active high, under the situation of trace or low concentration, polypeptide can both be brought into play its unique physiological action.It also has anti-freezing and thrombolytic effect except the general utility functions with polypeptide, and can bring into play unique effect through blood-brain barrier.
2, as base nutrients matter, polypeptide is than the easier absorption of amino acid, bioavilability height.Some low molecular peptide class also has diseases prevention simultaneously, cures the disease, and regulates the effect of human body physiological function, and these effects are that crude protein and the amino acid formed thereof are not available.Acid polypeptide at normal temperatures and pressures because its peptide chain is shorter than protein, its stability is more much higher than protein, thus needn't add any stabilizing agent in use just can long preservation, this provides scientific basis for Acid polypeptide is applied on food.
The specific embodiment
The extraction of Acid polypeptide of the present invention or processing technology embodiment:
Embodiment 1-1
The live body class leech of sucking blood is cleaned and to be placed on the beater making beating, use centrifuge centrifugal then, with filter below 100 microns or filter membrane filtration, put freezer freezing below 4 ℃ again.
Embodiment 1-2
The stem body class leech of sucking blood is pulverized with pulverizer, used the physiological saline lixiviate again 5 hours, concentrate again and preserve or put freezer freezing below 4 ℃.
Embodiment 1-3
Utilizing induced liquid to stimulate the leech live body that it is salivated, is raw material with these salivas then, extracts through centrifugal, gel chromatography.Chinese patent (application number: method extraction 03113566) according to inventor's application in 2003.
Embodiment 1-4
Be that the stem body class leech of sucking blood is pulverized with micronizer, cross 200-1000 purpose sieve.
Acid polypeptide food processing technology embodiment of the present invention
Embodiment 2-1
Acid polypeptide 10g, corn flour 10000g puts into corn flour with polypeptide, mix the back the polypeptide corn flour.
Embodiment 2-2
Acid polypeptide 50g, rice meal 10000g, lysine 20g, methionine 10g, be mixed together after respectively above-mentioned four kinds of raw materials being weighed up evenly polypeptide nutrition food.
Embodiment 2-3
Acid polypeptide 100g, flour 10000g makes bulk after with suitable quantity of water above-mentioned two kinds of raw materials being mixed, put into drying in oven polypeptide biscuit.
Embodiment 2-4
Acid polypeptide 300g, medical starch 10000g will incapsulate every 15～0.5g, every day 2 times, each 2～3 after above-mentioned two kinds of raw materials mixing.
Embodiment 2-5
Acid polypeptide 200g, clean water 10000g, with polypeptide add mix in the clean water back polypeptide oral liquor.
Embodiment 2-6
Acid polypeptide 250g, milk 10000ml, with polypeptide add mix in the milk back polypeptide milk.
Embodiment 2-7
Acid polypeptide 15g, coffee 35g, with above-mentioned two kinds of raw materials mix the back polypeptide coffee.
Embodiment 2-8
Acid polypeptide 15g, Radix Isatidis granules 1000g, with above-mentioned two kinds of raw materials mix the back the polypeptide Radix Isatidis granules.
Embodiment 2-9
Acid polypeptide 50g, spirulina 1000g, with above-mentioned two kinds of raw materials mix the back the polypeptide spirulina.
Embodiment 2-10
Acid polypeptide 100g, compound sugar or glucose 1000g, with above-mentioned two kinds of raw materials mix the back polypeptide glucose, polypeptide compound sugar.
Embodiment 2-11
Acid polypeptide 70g, what break into powdery bakes thin pork 1000g, with above-mentioned two kinds of raw materials mix the back the polypeptide powder of pork.
Embodiment 2-12
Acid polypeptide 60g, asparagus juice 1000ml, with polypeptide add asparagus juice stir the back the polypeptide asparagus juice.
Embodiment 2-13
Acid polypeptide 100g, soybean, Semen phaseoli radiati polypeptide 1000g, with above-mentioned two kinds of raw materials mix the back complex polypeptide food.
Embodiment 2-14
Acid polypeptide 200g, hawthorn powder 1000g, with above-mentioned two kinds of raw materials mix the back the polypeptide hawthorn powder.
Embodiment 2-15
Acid polypeptide 150g, what break into powdery bakes leptobos digested tankage 1000g, with above-mentioned two kinds of raw materials mix the back polypeptide powder.
Embodiment 2-16
Acid polypeptide 1000g, Eupolyph aga sinesis Walker 1000g, with above-mentioned two kinds of raw materials mix the back the polypeptide Eupolyph aga sinesis Walker, in this powder incapsulated, every 0.3g, each 2～4, had obvious curative effects to the control cardiovascular and cerebrovascular disease at every day 2～3 times.
Embodiment 2-17
Acid polypeptide 500g, egg 2000g, the above-mentioned three kinds of raw materials of flour 5000 gram add water and transfer and make the polypeptide baking egg pancake after mixing.
Embodiment 2-18
Acid polypeptide 300g, soya-bean milk 1000ml, with polypeptide add in the soya-bean milk polypeptide soybean milk.
Embodiment 2-19
Acid polypeptide 500g, pearl powder, corn flour 1000g, with above-mentioned two kinds of raw materials mix the back polypeptide pearl corn flour.
Embodiment 2-20
Acid polypeptide 100g, soya-bean milk 1000g adds polypeptide in the soya-bean milk that soybean makes, and stirs, add coagulating agent again it solidified, polypeptide bean curd.
Embodiment 2-21
Acid polypeptide 300g, earthworm 500g adds polypeptide in the bean jelly and smashs to pieces, mix polypeptide earthworm powder.
Embodiment 2-22
Acid polypeptide 150g, flour or konjaku flour 1000g, soya bean slurry 25g mixes above-mentioned raw materials, last machine is suppressed, the polypeptide vermicelli.
Polypeptide food of the present invention can reduce blood fat and cholesterol, and treatment prostatitis and alleviation hypertension below are implementation results:
Lee * *, man, life in 1958, Yulin City of Guangxi Zhuang Autonomous people, because of suffering from high fat of blood, in certain hospitalize, take the Western medicine Lovastatin at the beginning of 2003, but symptom makes moderate progress, but the symptom commentaries on classics of not getting better after the drug withdrawal, after change and take " the polypeptide Eupolyph aga sinesis Walker of embodiment 2-16 ", every day 2 times, each 0.3 gram takes that frequent dizzy symptom takes a turn for the better after 30 days, after taking 2 months, symptom all disappears, and spirit takes a turn for the better, muscle power increases, and it is normal that blood fat recovers, and feels good.
Open * *, the woman, nineteen forty-one gives birth to, Guangdong Lianjiang people, suffer from hypertension at examination in hospital March 5 calendar year 2001, often dizzy, asthma upstairs is not in hospital owing to lack of capital, and takes " polypeptide earthworm powder ", every day 2 times, each 0.3 gram is taken 5 all aftersensation and is got that sb.'s illness took a favorable turn, and dizziness alleviates.
Claims (5)
1, a kind of polypeptide food is made up of Acid polypeptide and auxiliary material that the class leech of sucking blood is extracted, and it is characterized in that: its material composition and quality percentage composition are as follows: Acid polypeptide 0.1～99.9%, auxiliary material 0.1%～99.9%;
Described Acid polypeptide is the low molecular polypeptide that 45-100 amino acid is formed.
2, polypeptide food according to claim 1 is characterized in that: Acid polypeptide adopts following extraction or processing technology to obtain:
(1) homogenate of live body leech is after centrifugal, ultrafiltration extraction;
(2) the stem body leech is pulverized back physiological saline lixiviate;
(3) utilizing induced liquid to stimulate the leech live body that it is salivated, is raw material with these salivas then, extracts through centrifugal, gel chromatography;
(4) stem body leech ultramicro grinding fine powder.
3, polypeptide food according to claim 1 is characterized in that: used auxiliary material derives from daily food, comprises following several or its combination:
(1) edible starch food products comprises cereal starch, potato starch, bean powder;
(2) meat, egg food, comprise can eat immediately through boiling, steam, bake, fry in shallow oil or the ready-made meat of other processing method, eggs;
(3) Western medicine, Chinese medicine or its extract;
(4) beverage;
(5) clean water that maybe can drink of pure water;
(6) carbohydrate food.
4, a kind of preparation method of polypeptide food as claimed in claim 1 is characterized in that: in proportion Acid polypeptide is joined in the auxiliary material, stir, mix and obtain food.
5, according to the preparation method of the described polypeptide food of claim 1, it is characterized in that: Acid polypeptide is mixed with auxiliary material do powdering, solid shape, capsule shape, paste body shape or liquid food, comprise and make health food, nutraceutical and bread and cheese.
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| CNA2005100364846A CN1729861A (en) | 2005-08-12 | 2005-08-12 | Polypeptide food and its production process |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107897642A (en) * | 2017-11-22 | 2018-04-13 | 广西远程水蛭养殖有限公司 | The method that leech nutritious soup makes |
| CN110623275A (en) * | 2019-09-18 | 2019-12-31 | 周维海 | Composite amino acid gilt-edged leech polypeptide food with anticoagulant and antithrombotic effects and preparation method thereof |
| CN114081186A (en) * | 2022-01-20 | 2022-02-25 | 南京浩明乳业有限责任公司 | Oligomeric polypeptide powder and processing technology thereof |
-
2005
- 2005-08-12 CN CNA2005100364846A patent/CN1729861A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107897642A (en) * | 2017-11-22 | 2018-04-13 | 广西远程水蛭养殖有限公司 | The method that leech nutritious soup makes |
| CN110623275A (en) * | 2019-09-18 | 2019-12-31 | 周维海 | Composite amino acid gilt-edged leech polypeptide food with anticoagulant and antithrombotic effects and preparation method thereof |
| CN114081186A (en) * | 2022-01-20 | 2022-02-25 | 南京浩明乳业有限责任公司 | Oligomeric polypeptide powder and processing technology thereof |
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