CN1720798A - Water dispersible tablet of flumorph - Google Patents
Water dispersible tablet of flumorph Download PDFInfo
- Publication number
- CN1720798A CN1720798A CN 200410020976 CN200410020976A CN1720798A CN 1720798 A CN1720798 A CN 1720798A CN 200410020976 CN200410020976 CN 200410020976 CN 200410020976 A CN200410020976 A CN 200410020976A CN 1720798 A CN1720798 A CN 1720798A
- Authority
- CN
- China
- Prior art keywords
- flumorph
- agent
- sodium
- aqueous dispersion
- tablets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BKBSMMUEEAWFRX-NBVRZTHBSA-N (E)-flumorph Chemical compound C1=C(OC)C(OC)=CC=C1C(\C=1C=CC(F)=CC=1)=C\C(=O)N1CCOCC1 BKBSMMUEEAWFRX-NBVRZTHBSA-N 0.000 title claims abstract description 36
- 239000004565 water dispersible tablet Substances 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract description 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 7
- 239000011230 binding agent Substances 0.000 claims abstract description 6
- 239000000080 wetting agent Substances 0.000 claims abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 5
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 27
- 239000006185 dispersion Substances 0.000 claims description 21
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 14
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 8
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 8
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 8
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 8
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 8
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 8
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 8
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 7
- 229940088417 precipitated calcium carbonate Drugs 0.000 claims description 7
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 6
- 239000007884 disintegrant Substances 0.000 claims description 6
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical group [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 claims description 6
- 239000002270 dispersing agent Substances 0.000 claims description 6
- 239000000741 silica gel Substances 0.000 claims description 6
- 229910002027 silica gel Inorganic materials 0.000 claims description 6
- 239000000945 filler Substances 0.000 claims description 5
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 claims description 3
- 239000000645 desinfectant Substances 0.000 claims description 3
- LWEAHXKXKDCSIE-UHFFFAOYSA-M 2,3-di(propan-2-yl)naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S([O-])(=O)=O)=C(C(C)C)C(C(C)C)=CC2=C1 LWEAHXKXKDCSIE-UHFFFAOYSA-M 0.000 claims description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 2
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims description 2
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
- 239000001175 calcium sulphate Substances 0.000 claims description 2
- 235000011132 calcium sulphate Nutrition 0.000 claims description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 229920000609 methyl cellulose Polymers 0.000 claims description 2
- 239000001923 methylcellulose Substances 0.000 claims description 2
- 235000010981 methylcellulose Nutrition 0.000 claims description 2
- 229940072033 potash Drugs 0.000 claims description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 2
- 235000015320 potassium carbonate Nutrition 0.000 claims description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 2
- 235000017550 sodium carbonate Nutrition 0.000 claims description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 2
- 235000011152 sodium sulphate Nutrition 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 235000019698 starch Nutrition 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- 238000007907 direct compression Methods 0.000 claims 1
- 238000010298 pulverizing process Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 5
- 238000003912 environmental pollution Methods 0.000 abstract description 4
- 239000004067 bulking agent Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 240000008067 Cucumis sativus Species 0.000 description 8
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 238000009472 formulation Methods 0.000 description 6
- 241000233679 Peronosporaceae Species 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 230000003449 preventive effect Effects 0.000 description 2
- 239000004563 wettable powder Substances 0.000 description 2
- 241001223281 Peronospora Species 0.000 description 1
- 241000233614 Phytophthora Species 0.000 description 1
- 241001281805 Pseudoperonospora cubensis Species 0.000 description 1
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000012136 culture method Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- -1 polyethylene pyrrolidones Polymers 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 238000001238 wet grinding Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a flumorph water dispersing tablet, which is prepared from flumorph reagents, crumbling agent, binding agent, effervescent agent, wetting agent, emulsifying agent, and bulking agent through mixing, disintegrating, and tabletting with total powder direct pelleting method. Compared with the traditional dosage types, the water dispersing tablet has the advantages of high effectiveness, ease and convenience in use, transportation and storage, less environmental pollution.
Description
Technical field
The invention belongs to the pesticide processing field, relate to novel form and the processing and the application of disinfectant use in agriculture flumorph (flumorph).
Background technology
Flumorph (flumorph) (chemical name: 4-[3-(this base of 4-fluorine)-3-(3, the 4-Dimethoxyphenyl) acryloyl] morpholine) is widely used in the control of various crop disease as disinfectant use in agriculture, especially Peronospora, Phytophthora germ is had special efficacy.The bactericidal activity and the preparation method of this compound and preparation thereof are disclosed among the Chinese patent CN1167568A.Along with the further expansion that flumorph is applied, find that there are many weak points in present applied formulation.For example: but the bad grasp of consumption when wet-milling uses, and especially the user is difficult for accurate weighing when low dose is used; Contain for example dimethylbenzene of a large amount of organic solvents in the missible oil, environmental pollution is serious; Two kinds of formulations store, transport all inconvenient simultaneously.
Summary of the invention
In order to overcome the bad grasp of consumption that existing formulation exists, store, transportation inconvenience and easily cause the shortcoming of environmental pollution, the present invention proposes a kind of flumorph tablet novel form.
Flumorph tablet of the present invention is an active component with the former powder of flumorph.The weight percentage of each component is as follows in the tablet: flumorph 0.1-50%, effervescent agent 4-20%, binding agent 3-10%, disintegrant 0.5-30%, wetting agent 0.5-20%, dispersant 0.5-30%, filler 0.5-20%.
Effervescent agent described in the prescription is two kinds, a kind of sodium carbonate, sodium bicarbonate or potash of being selected from; Another kind is selected from citric acid or citric acid; Preferred sodium carbonate and citric acid.Described binding agent is selected from industrial starch, carboxymethyl cellulose, methylcellulose or polyvinylpyrrolidone, the preferably polyethylene pyrrolidones.Described disintegrant is selected from microcrystalline cellulose, Ac-Di-Sol, sodium carboxymethylcellulose, cross linked polyvinyl pyrrolidone or hydroxypropyl cellulose, preferably microcrystalline cellulose.Described wetting agent is selected from bay alcohol radical sodium sulphate, neopelex or lauryl sodium sulfate, preferred neopelex.Described dispersant is selected from sodium lignin sulfonate, NNO or nekal, preferred sodium lignin sulfonate or NNO.Described filler is selected from lactose, calcium sulphate, sucrose, talcum powder, silica gel, dolomol or precipitated calcium carbonate, preferably talc powder, silica gel, dolomol or precipitated calcium carbonate.
More preferably aqueous dispersion tablets in the Tabules of the present invention.The disintegrant of selecting for use in the above-mentioned prescription can be accelerated the disintegration rate of tablet in water, wherein especially with the microcrystalline cellulose best results.Add two or more dispersants and can improve the dispersion effect of this tablet in water, for example can equal proportion add sodium lignin sulfonate and NNO.
According to above-mentioned prescription, material is fully mixed, make it to reach 325 orders through ultramicro grinding, adopt full powder dry powder direct tabletting method processing technology direct tablet compressing.The flumorph aqueous dispersion tablets that can prepare in this way, the various content of the present invention.The prepared aqueous dispersion tablets of the present invention weighs 40 milligrams, and 5 millimeters of diameters also can prepare the tablet of other different sizes according to application need.
Compare with the wet method tablet forming technique, owing to omitted granulation, baking operation, this processing technology can shorten production cycle and energy savings, enhances productivity.This technology also is applicable to the formulation processing of other thermo-responsive medicines, can prevent that thermo-responsive medicine from decomposing institute's content extremely and descending the minimizing loss of active ingredients.Compare with the wet method tablet forming technique, this technology can also further be improved the disintegration of tablet time.
Advantages such as flumorph aqueous dispersion tablets of the present invention also has convenient, the transportation safety of use accurate measurement, is beneficial to store and the container configuration, and is easy to carry, and environmental pollution is little.Application effect is suitable with existing formulation.For example the flumorph aqueous dispersion tablets under identical treatment dosage to the preventive effect of cucumber downy mildew in seedling stage near or slightly be better than the control efficiency of the wettable powder preparation of flumorph to cucumber downy mildew.
Preferred forms
Following example is in order to further specifying the present invention, but and unrestricted the present invention.
Formulation examples:
Fully mix according to the various materials shown in the following prescription, direct tablet compressing after ultramicro grinding makes it to reach 325 orders promptly obtains the flumorph aqueous dispersion tablets that sheet weighs 5 millimeters of 40 milligrams, diameter.
Embodiment 1 35% flumorph aqueous dispersion tablets
Former medicine 35 grams of flumorph
Microcrystalline cellulose 14 grams
Polyvinylpyrrolidone 4 grams
Sodium carbonate 6 grams
Citric acid 6 grams
NNO 5 grams
Sodium lignin sulfonate 5 grams
Neopelex 1 gram
Dolomol 2 grams
Talcum powder 2 grams
Precipitated calcium carbonate complements to 100 grams
Embodiment 2 30% flumorph aqueous dispersion tablets
Former medicine 30 grams of flumorph
Microcrystalline cellulose 11 grams
Polyvinylpyrrolidone 2 grams
Sodium carbonate 6 grams
Citric acid 6 grams
NNO 5 grams
Neopelex 1 gram
Dolomol 1 gram
Silica gel 2 grams
Precipitated calcium carbonate complements to 100 grams
Embodiment 3 20% flumorph aqueous dispersion tablets
Former medicine 20 grams of flumorph
Microcrystalline cellulose 16 grams
Polyvinylpyrrolidone 4 grams
Sodium carbonate 6 grams
Citric acid 6 grams
NNO 5 grams
Neopelex 1 gram
Dolomol 1 gram
Silica gel 2 grams
Talcum powder 1 gram
Precipitated calcium carbonate complements to 100 grams
The water dispersible test
Embodiment 4
The dispersivity test of aqueous dispersion tablets adopts following method: under the room temperature, add about 800 ml tap waters in the container that the top can seal.Add 2 of aqueous dispersion tablets of the present invention and airtight container top, can observe aqueous dispersion tablets and disperse.For the flumorph aqueous dispersion tablets of embodiment 1,2,3, drop down onto container bottom and begin and disperse, can observe it and disperse fully to be no more than 3 minutes.
The test of pesticide effectiveness
Embodiment 5 cucumber downy mildew control efficiency
Adopt greenhouse seedling pot-culture method to measure the control efficiency of flumorph aqueous dispersion tablets, and compare with the flumorph wettable powder to cucumber downy mildew.Cucumber variety: the close thorn in Shandong, pathogen: cucumber downy mildew in seedling stage germ (Pseudoperonospora cubensis).When the greenhouse pot culture cucumber seedling grows to tri-leaf period, on the crop sprayer, carry out foliar spray by design dosage and handle, inoculate pathogen after 24 hours.Preserve moisture after the inoculation to cultivate and carry out result's investigation after 7 days.The flumorph aqueous dispersion tablets of the various content of the present invention all has good preventive effect and do not find has any harmful effect to cucumber growth.
The control efficiency of 30% flumorph aqueous dispersion tablets sees the following form:
Claims (6)
1, flumorph tablet, the weight percentage of each component is as follows:
Flumorph 0.1-50%
Effervescent agent 4-20%
Binding agent 3-10%
Disintegrant 0.5-30%
Wetting agent 0.5-20%
Dispersant 0.5-30%
Filler 0.5-20%.
2, according to the described flumorph tablet of claim 1, be characterised in that: described effervescent agent is two kinds, a kind of sodium carbonate, sodium bicarbonate or potash of being selected from; Another kind is selected from citric acid or citric acid; Described binding agent is selected from industrial starch, methylcellulose, carboxymethyl cellulose or polyvinylpyrrolidone; Described filler is selected from lactose, calcium sulphate, sucrose, talcum powder, silica gel, dolomol or precipitated calcium carbonate; Described disintegrant is selected from microcrystalline cellulose, Ac-Di-Sol, sodium carboxymethylcellulose, cross linked polyvinyl pyrrolidone or hydroxypropyl cellulose; Described wetting agent is selected from bay alcohol radical sodium sulphate, neopelex or lauryl sodium sulfate; Described dispersant is selected from sodium lignin sulfonate, NNO or nekal.
3, according to claim 1 or 2 described flumorph tablets, be characterised in that: effervescent agent is selected from sodium carbonate and citric acid; Binding agent is selected from polyvinylpyrrolidone; Filler is selected from talcum powder, silica gel, dolomol or precipitated calcium carbonate; Disintegrant is selected from microcrystalline cellulose; Wetting agent is selected from neopelex; Dispersant is selected from sodium lignin sulfonate or NNO.
4, according to claim 1 or 2 described flumorph tablets, be characterised in that: be aqueous dispersion tablets.
5, the preparation method of the described flumorph aqueous dispersion tablets of claim 4: each component adopts direct compression of full-powder method compressing tablet after mixing, pulverizing.
6, the flumorph aqueous dispersion tablets is as the purposes of disinfectant use in agriculture.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100209761A CN100382694C (en) | 2004-07-16 | 2004-07-16 | Water dispersible tablet of flumorph |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100209761A CN100382694C (en) | 2004-07-16 | 2004-07-16 | Water dispersible tablet of flumorph |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1720798A true CN1720798A (en) | 2006-01-18 |
| CN100382694C CN100382694C (en) | 2008-04-23 |
Family
ID=35911691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100209761A Expired - Lifetime CN100382694C (en) | 2004-07-16 | 2004-07-16 | Water dispersible tablet of flumorph |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100382694C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101999348A (en) * | 2010-10-26 | 2011-04-06 | 江苏七洲绿色化工股份有限公司 | Preparation method of pesticide effervescent tablet |
| CN103385249A (en) * | 2012-05-09 | 2013-11-13 | 中国中化股份有限公司 | Antifungal composition containing flumorph and prochloraz |
| CN103540161A (en) * | 2012-07-09 | 2014-01-29 | 沈阳新纪化学有限公司 | Water-soluble tablet of fluorescent brightener 351 as well as preparation method and application of water-soluble tablet |
| CN106942247A (en) * | 2017-04-21 | 2017-07-14 | 扬州大学 | Emamectin-benzoate effervescent tablet and preparation method thereof |
| CN113545344A (en) * | 2021-07-23 | 2021-10-26 | 安徽省通源环境节能股份有限公司 | Submerged plant growth-promoting sustained-release tablet and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716630A (en) * | 1996-06-21 | 1998-02-10 | Zeneca Limited | Pesticidal tablet formulations |
-
2004
- 2004-07-16 CN CNB2004100209761A patent/CN100382694C/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101999348A (en) * | 2010-10-26 | 2011-04-06 | 江苏七洲绿色化工股份有限公司 | Preparation method of pesticide effervescent tablet |
| CN101999348B (en) * | 2010-10-26 | 2013-01-02 | 江苏七洲绿色化工股份有限公司 | Preparation method of pesticide effervescent tablet |
| CN103385249A (en) * | 2012-05-09 | 2013-11-13 | 中国中化股份有限公司 | Antifungal composition containing flumorph and prochloraz |
| CN103385249B (en) * | 2012-05-09 | 2014-07-23 | 中国中化股份有限公司 | Antifungal composition containing flumorph and prochloraz |
| CN103540161A (en) * | 2012-07-09 | 2014-01-29 | 沈阳新纪化学有限公司 | Water-soluble tablet of fluorescent brightener 351 as well as preparation method and application of water-soluble tablet |
| CN106942247A (en) * | 2017-04-21 | 2017-07-14 | 扬州大学 | Emamectin-benzoate effervescent tablet and preparation method thereof |
| CN113545344A (en) * | 2021-07-23 | 2021-10-26 | 安徽省通源环境节能股份有限公司 | Submerged plant growth-promoting sustained-release tablet and preparation method thereof |
| CN113545344B (en) * | 2021-07-23 | 2022-08-09 | 安徽省通源环境节能股份有限公司 | Submerged plant growth-promoting sustained-release tablet and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100382694C (en) | 2008-04-23 |
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Effective date of registration: 20160121 Address after: 110021 Liaodong Road, Tiexi District, Liaoning, No. 8-1, No. Patentee after: SHENYANG SINOCHEM AGROCHEMICALS R&D Co.,Ltd. Address before: 100031 Beijing, Xicheng District, the door of the revitalization of the main street, No. 28 Patentee before: SINOCHEM Corp. Patentee before: SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY Co.,Ltd. |
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