CN1717997A - Method for preparing complex microemulsion contg. bisultap mother liquor and high efficiency cypermethrin - Google Patents

Abstract

A Composite insecticide microemulsion for the pests of rice is prepared from the bisultap solution, high-effect cypermethrin, organic cosolvent, efficient penetrant, surfactant and water through proportional mixing and stirring.

Description

Produce the method for complex microemulsion with dimehypo mother liquor and beta-cypermethrin combination

The invention belongs to the complex microemulsion of chemical pesticide.The dimehypo mother liquor is meant isolates a large amount of mother liquor aquas under the residue behind the desinsection single crystals, dimehypo and desinsection list are that China develops successful nereistoxin (Nereistoxin) analog insecticide voluntarily, have tag, stomach toxicity, interior suction and have certain fumigation action concurrently, two once was the main control medicament of China paddy rice primary pest striped rice borer, paddy stem borer, pink rice borer, rice plant skipper, rice leaf roller, rice thrips, rice leafhopper during the last ten years.It is that the nerve synapse blocking agent can interrupt that the insect nerve impulse is transmitted the blockage of acetylcholine receiver, makes insect lose regulative mechanism, is absorbed in paralysis, food refusal and dying, and mechanism of action is unique, the outstanding insecticide of can yet be regarded as.Yet because long-term the use, the pesticide resistance of insect is constantly aggravated in recent years, causes dosage constantly to increase, this rising of farming.Because dimehypo, desinsection list once were China substitutes the principal item of 666 organochlorine insecticides, become the principal item of the malicious organic phosphor of alternative height again now, seek to overcome for this reason its pesticide resistance, to improve drug effect, reduce consumption, enlarge insecticidal spectrum, improve the economic and social benefits be purpose of the present invention.In research repeatedly, experiment and living the survey on the basis of screening have been selected the biologically active height, mechanism of action is to prolong the insect sodium-ion channel to open and the pyrethroid insecticides of the super excited insect that causes death: beta-cypermethrin (comprises alpha-cypermethrin, permethrin, cyhalothrin, trebon, agent of decis list or mixture) add a small amount of cosolvent with dimehypo mother liquor aqua (comprising dimehypo water solution), add surfactant, high-efficient penetrant, water is that matrix is mixed with clarification, transparent, microemulsion (the microemulsion that homogeneous is single-phase, ME), microemulsion is the external a kind of pesticides new formulation that the occurs eighties in 20th century, because microemulsion is main solvent with water, alleviated environmental pressure greatly after not only having saved a large amount of organic solvents and dispenser, significant for safeguarding agroecological environment, help the sustainable development of agricultural, be that the environment friendly agricultural preparation receives publicity.

Dimehypo chemical name: N, N dimethylamine base-1,3-two thiosulfonic acid sodium base propane

Structural formula:

The beta-cypermethrin chemical name: (1R, S)-suitable, trans-2,2-dimethyl-3-(2, the 2-dichloroethylene) cyclopropane-carboxylic acid-(±)---α cyano group-(3-phenoxy group)-benzyl ester.The ratio of wherein suitable, trans optical isomer is 40: 60

Structural formula

The invention has the beneficial effects as follows: production technology and equipment are simple, the normal temperature and pressure operation, the preparation required time is short, production cost is low, do not produce secondary pollution, the microemulsion clarification of making, transparent, homogeneous is single-phase.Through the conventional sensitivity variation of depositing four seasons difference variation monitoring tracking one year over, finding no proterties, as before as clear as crystal.This microemulsion is the resistance that overcomes dimehypo, it is former just to the drawback of weak effects such as rice fulgorid to overcome dimehypo; Make simultaneously not only super-high-efficient insecticide that this insecticidal spectrum of beta-cypermethrin is extremely wide but also above-mentioned paddy rice primary pest had remarkable control efficiency, be used for paddy rice already as states such as Japan, Malaysia, Philippine abroad, yet because it has high poison to cause domestic waiting to be lifted a ban to aquatic organism, at this drawback, microemulsion of the present invention is overcome as emphasis in development prescription process, through carp test toxicity LC ₃₀Be＜3PPM, thereby the ichthyotoxin that makes single agent beta-cypermethrin is by LC ₅₀Be 0.3PPb, greatly reduce, make this agent be used for paddy rice and become possibility, microemulsion can be miscible with any ratio with water, active ingredient particulate only (0.05～0.1 μ m) behind dilute with water during dispenser has added high osmotic agent again and has easily been oozed or absorb by the target exhibition, preparation make accumulating and safe in utilization, environmental pressure is little, thereby in case put into production and substitute high malicious organic phosphorous insecticide one big new product and make new contributions again again will become now, thereby produce huge economic benefit and social benefit.Because after having added super-high-efficient insecticide beta-cypermethrin in the dimehypo, the synergistic function of the microemulsion that two kinds of different pesticide compositionals of the mode of action form, thus can alleviate pesticide resistance that each single agent produced because of long-term use, reduced usage amount, enlarged insecticidal spectrum, increased applicability, Environmental compatibility and safety.The dimehypo mother liquor adds efficient cypermethrin microemulsion, and to can be used for paddy rice control striped rice borer, paddy stem borer, pink rice borer, rice plant skipper, rice thrips, rice leaf roller, rice leafhopper, rice fulgorid consumption be 25～35ga.i/667m ², and dimehypo, desinsection list consumption are 50～90ga.i/667m at present ²Also can be used for corn control of maize snout moth's larva, noctuid, aphid, be used for oranges and tangerines controls dive noctuid, ceroplastes rubens, mealybug, aphid, be used for sugarcane control thrips, bar snout moth's larva, pink rice borer, aphid, little cycle of sixty years, leaf and resemble, also can be used for apple and other drupe class crops control primary pest.

To sum up, if adopt the desinsection single crystals add efficient cypermethrin make microemulsion, with add efficient cypermethrin microemulsion with agent with the dimehypo mother liquor of amount and compare, then product unit's cost that dispatches from the factory will increase about 30%, by contrast, the dimehypo mother liquor adds not only economic benefit height of efficient cypermethrin microemulsion, the synergy of a large amount of dimehypo mother liquor, increment in the production be can make simultaneously, and new purposes and new business opportunity opened.

Content of the present invention is, with dimehypo mother liquor (comprising dimehypo water solution) content of effective in complex microemulsion is 5～40% (w/w), beta-cypermethrin (comprising above-mentioned chrysanthemum ester) content in complex microemulsion is 0.1～5% (w/w), beta-cypermethrin is dissolved in following cosolvent: toluene, dimethylbenzene, dimethyl formamide, methyl alcohol, ethanol, isopropyl alcohol, acetone, in one of them the single agent or their mixture of cyclohexanone, add high-efficient penetrant: ammonia ketone, thiophene ketone one of them, add non-ionic surface active agent: 601,602,603, NP15, NP20, AEO-9, AO-12, anion surfactant: 505,506,507, non-, anion surfactant 2201, the mixture of one of them or they, ratio is, dimehypo: beta-cypermethrin: cosolvent: high osmotic agent: surfactant is 5～40: 0.1～5: 2～20: 0.1～1: 20～30 (%, w/w), in enamel reaction still, stir with electronic agitator after, adding a certain amount of dimehypo mother liquor aqua is stirred to and is clarification, transparent, homogeneous single phase soln.

The present invention has following embodiment: be furnished with in the enamel reaction still of electric mixer at 100 liters under the normal temperature and pressure, drop into 5 kilograms of methyl alcohol, 5 kilograms of isopropyl alcohols, drop into beta-cypermethrin (pure) 0.5 kilogram, 0.3 kilogram of thiophene ketone, after the stirring and dissolving, add 603 10 kilograms of farming breasts, 8 kilograms of NP-15,2,201 3 kilograms, be stirred to homogeneous, after transparent, dimehypo mother liquor aqua with 25.8% slowly adds 60 kilograms in stirring, be supplemented to 100 kilograms with clear water again, continue to stir 30～45 minutes, be clarification, transparent, the dimehypo mother liquor of homogeneous single phase soln adds efficient cypermethrin microemulsion preparation to be finished.

Claims (3)

1. the preparation method of a pesticide compositional microemulsion, it is characterized in that it with the two mother liquors of agricultural insecticide, comprise dimehypo water solution, comprise that with beta-cypermethrin alpha-cypermethrin, permethrin, cyhalothrin, decis, their single agent of trebon or mixture are raw material, add cosolvent, high-efficient penetrant, nonionic, anion or mixed surfactant, with the clear water is matrix, produces clarification, transparent, complex microemulsion that homogeneous is single-phase at normal temperatures and pressures in enamel reaction still.

2. the preparation method of complex microemulsion according to claim 1, the content that it is characterized in that dimehypo in the complex microemulsion is 5～40% (w/w), beta-cypermethrin comprises that the active constituent content of above-mentioned chrysanthemum ester veriety is 0.1～5% (w/w).

3. the preparation method according to right 1 described complex microemulsion is characterized in that ratio is a dimehypo in the preparation: beta-cypermethrin: cosolvent: high-efficient penetrant: surfactant is 5～40: 0.1～5: 2～20: 0.1～1: 20～30, dimehypo mother liquor in this material is treated to add rest materials stirs homogeneous earlier under the normal temperature and pressure in enamel reaction still after again, continue to stir 30 minutes to 1 hour.