CN1711859A - Fermented milk sheets with auxin - Google Patents

Abstract

A sour milk tablet containing auxin for promoting cerebral functions and bone growth, and improving memory power is prepared from the fresh milk through filtering, proportionally mixing it with perilla oil, alpha-linolenic acid, lecithin, vitamins, minerals, taurine, etc, preheating, homogenizing, sterilizing, concentratie. inoculating, fermenting, spray drying, tablectting, examining and packing.

Description

Fermented milk sheets with auxin

One, technical field: the invention belongs to the common food technology field of strengthening function; relate in particular to sour milk perilla herb oil, lecithin, Taurine, L-tryptophan, L-glutamic acid, L-glutaminase, L-asparatate, L-arginine, vitamin A, vitamin E, vitamin D ₃, vitamin K ₂, Cobastab ₁, Cobastab ₂, Cobastab ₆, Cobastab ₁₂, the common food of strengthening function that processes of raw material such as folic acid, nicotinic acid, vitamin C, biotin, calcium, zinc, iron, phosphorus, magnesium, potassium, manganese, iodine, inulin.

Two, background technology: the present invention is base-material with fresh milk through the sour milk that the interpolation lactobacillus-fermented forms, strengthened the functional yoghourt sheet that perilla herb oil, lecithin, amino acid, vitamin, mineral matter and trace element etc. process, this sour milk tablet has promotion to grow with bone growth, improve unique trophic function such as memory, growth encourage to children and youth.Sour milk has only liquid beverage at present, does not have the functional yoghourt sheet to occur, and development functional yogurt sheet can be the dairy products industry provides a kind of novel functional yogurt sheet.The both comprehensive nutrition equilibriums of this sour milk tablet have health care again, and adopt pharmaceutical dosage form health foods such as tablet, capsule, oral liquid to compare with present great majority, and fermented milk sheets with auxin obviously all more has affinity on mouthfeel and form.

Three, summary of the invention: The present invention be directed to the serious hope of children and youth to cultural scientific knowledge, the special dietary demand that it grows fast and a kind of functional yoghourt sheet of developing, this sour milk tablet has the brain function growth and the bone growth of promotion, improves multiple functions such as memory, growth encourage.Its outward appearance is a milk yellow, does not have any peculiar smell, has the fragrance and the sour-sweet fruity of yoghurt, and mouthfeel is soft, and is slick and sly tasty and refreshing.

Four, composition of raw materials: 90 kilograms of fresh milks; 2.5 kilograms of leavenings; 1 kilogram of yeast 50 grams, white sugar, 2 kilograms in grape powder, 0.8 kilogram of perilla herb oil, lecithin 600 grams, Taurine 40 grams, L-tryptophan 400 grams, L-glutamic acid 320 grams, L-glutamine 800 grams, 1.2 kilograms of L-arginine, L-asparatate 480 grams, 2 kilograms of inulin, 3-Hydroxyretinol .2 milligram, vitamin E 6 grams, vitamin D ₃4 milligrams, vitamin K ₂0.03 gram, Cobastab ₁2 grams, Cobastab ₂2.4 gram, Cobastab ₆1 gram, Cobastab ₁₂2 milligrams, folic acid 0.14 gram, nicotinic acid 4 grams, vitamin C 40 grams, 20 milligrams of biotins, 3.7 kilograms of calcium lactates, zinc gluconate 45 grams, ferrous lactate 48 grams, phosphate 5.6 grams, magnesium chloride 800 grams, manganese sulfate 2.6 grams, KI 0.02 gram, copper carbonate 0.8 gram.

Five, technical scheme

(1) sour milk: sour milk is to be raw material with the fresh milk, through having added the leavening of different strain, the dairy products that fermentation forms.The equilibrium of sour milk comprehensive nutrition, the functional food of easily digesting and assimilating is often drunk and can be regulated function of intestinal canal, strengthens immunity, promote to grow, to improve intelligence, beauty treatment, hypotensive, suppress cholesterol, delay senility, multiple function such as pre-anti-cancer, be a kind of nutriment of function uniqueness.

Sour milk contains 100 multiple nutritional components, compositions such as protein, fat, carbohydrate, vitamin, mineral matter, cell nutritious element and growth factor.Wherein the amino acid ratio of 8 kinds of needed by human is suitable, is particularly suitable for children and youth and grows, and builds up health and immunity function, and it is indispensable improving school grade.

Protein in the sour milk is suckled sweet and valine, methionine etc. owing to resolve into fine solidifying through lactobacillus-fermented.Therefore easier absorption, the utilization rate of raising protein.Protein is one of nutrient of people Lai Yi existence.Medical science thinks that protein is the important substance basis that brain tissue is grown metabolism, be to preside over the excitement of brain cell and the main matter of process of inhibition, in multiple functions such as memory, language, thinking, motion, nerve conduction, in human brain cellularity material, remove fat and account for 60%, other is exactly that protein accounts for 35%, provides enough nutrients for increasing brain function.Sufficient protein has facilitating effects to children in addition.Calcium generates calcium lactate and is convenient to absorption of human body in the sour milk under the effect of lactic acid, and the prevention senile osteoporosis is promoted that the children and youth bone growth and development is very important.Contain necessary vitamin of human body and mineral matter in the sour milk, as the A that supports one's family, B ₁, B ₂And iron, magnesium, potassium, zinc, selenium and other trace elements, to keeping the normal function of human body, promote that growing, improve immunity plays an important role.Studies show that often drinking sour milk has certain effect to promoting children's intelligence and nervous system brain growth.Lactic acid bacteria and Bifidobacterium in the sour milk have the function of intestinal canal of improvement, and prevention elderly constipation and raising human body are to the absorption of mineral calcium, phosphorus, iron.

Sour milk brain tonic, the main component in the brain be protein, lipid (mainly being lecithin) to the influence of brain growth more calcium, Cobastab arranged ₁, niacin, Taurine, zinc, iron etc., its calcium is the activator of nerve cell metabolism, and the function and the metabolism of brain had very important effect.The hormone of cerebral nerve mediator and pituitary gland secretion almost all derives from the protein in the food, amino acid.The necessary nutritional labelings of human body such as the calcium in the milk, protein, vitamin, butterfat, mineral matter, absorbed the back by body and participate in the neuromuscular activity, strengthen cerebral nerve and organize conduction function, activate brain nervous cell, improve intelligence, this shows that sour milk not only had been healthy and strong but also brain tonic, is the brain tonic good merchantable brand that suits the taste of both old and young.

Sour milk encourages, and discovering in the life earliest period has the women of the custom of having milk to have higher bone density.Period have milk be of value at children and adolescents more and grow, reach best peak bone density.The bone normal growth is grown, and look not only thick but also long, constantly keep simultaneously the positive calcium balance state of growth and development stage, the abundance of the human nutrition element that human bodies such as proteins,vitamins,minerals are necessary is supplied with, and just can keep brain, muscle, blood and hetero-organization organ thereof and carry out normal physiological activity and grow.Just because of milk contains the necessary for human body rich nutrient contents, and the utilization that easily is absorbed by the body, so drink milk helps growing of children and youth.Can facts have proved scientifically raise child may make its height differ tens centimetres.

Need participate in suitable physical training drink milk the time in addition, help growing of bone, muscle, promote growth hormone secretion, promote organism metabolism, can play the effect of growth encourage.

(2) vitamin A (VitA) has another name called retinol (Retinol), is by 20 carbon or 40 unsaturated monohydric alcohols that carbon atom constitutes, and comprises vitamin A (retinol) and vitamin A ₂(3 one take off retinol).Vitamin A character in the natural food is relatively stable, temperature that ability is higher and soda acid, the easy oxidation of ultraviolet ray irradiation.Vitamin E in the food, C and other antioxidants help to protect the activity of vitamin A.

Physiological function: 1, vitamin A is kept normal growth, it is a kind of micronutrient of broad-spectrum physiological role, its active metabolite is a retinoic acid, and many-sided form all has effect in the vertebrate embryo development procedure, affects the genesis and development and the nerve of a plurality of histoorgans.

2, vitamin A be constitute bone and the tooth normal development necessary, he can promote the growth of bone and tooth, this may have in the bone of promotion osteocyte with it and form relevantly, so vitamin A is to infant and children's particular importance.

3, strengthen immunity: studies show that in the serum to be remarkable positive correlation between the vitamin a level and periphery blood T cell percentage and lymphocyte transformation rate.Cell is cultivated and is shown that the vitamin A of physiological concentration has obvious facilitation to the generation of lymphocyte antibody.Vitamin A can obviously increase the thymic weight of rat, and the pulmonary macrophage number also strengthens its phagocytic function.

Vitamin A is kept the complete of normal eyesight and epithelial tissue structure in addition with sound in addition, anti-oxidant control cardiovascular and cerebrovascular disease and multiple function such as antitumor.

VAD: 1, to the influence of brain growth, retinoic acid plays an important role in brain growth embryonic period, embryonic phase, and is all influential to the growth of the formation of the part of brain and neural myelin, differentiation, cerebellum, midbrain.Nutritional deficiency or unbalanced all may making are in budding children and produce Mental retardation, failure of memory, and IQ is low inferior.

2, VAD makes child development slow, at first influences skeleton development, and wherein bone tissue stops growing, and tooth generation hyperplasia and angling influence the enamel cell development tooth is stopped growing simultaneously.Bone in children in the growth increases slow.Exactly because VAD influences appetite, and the frequent generation of infectious diseases.Therefore VAD is very big to the upgrowth and development of children influence.Zoopery finds that the A that is deficient in vitamin slightly lacks bone, and dental enamel is easily peeled off and followed the string, and carious tooth easily takes place.Recent study finds that again of short and small stature is children's growth hormone secretion at night minimizing of VAD.In addition, VAD causes that also eyesight descends, and immunity function hangs down inferior symptom.

(3), vitamin E (Vit E) has another name called Vitamin E (Ctocopherol).Be that α, β, y and δ-Vitamin E α, β, y and δ one triolefin Vitamin E are called vitamin E with family system for 8 kinds.Wherein the biologically active of α-Vitamin E is the highest.Vitamin E belongs to liposoluble vitamin, and is water insoluble, to the oxygen sensitivity, be easy to oxidation and destroy, can quicken its oxidation especially under illumination, heat, alkali condition, more stable under acid and oxygen free condition.

Physiological function: 1, anti-oxidant, vitamin E is a kind of very strong antioxidant, avoids the infringement of free radical at the protection cell membrane.Brain tissue cell contains a large amount of unrighted acids, and vitamin E can prevent the oxidation of unrighted acid, thereby the eubolism of protection brain cell prevents the brain oxidation and fails with movable.Human megavitamin E is arranged and child and children's intelligence obstacle are significantly improved, vitamin E also can prevent the oxidation of vitamin A, vitamin C and ATP.Guarantee their functions in vivo.

2, vitamin E has neuroprotective system, skeletal muscle, retina to avoid oxidative damage.The normal development of nerve system of human body and retinal function need sufficient vitamin E.With a large amount of free-radical generating, so vitamin E is preventing mitochondria and is neurally touching prominent film to avoid aspect the radical damage be essential that vitamin E has the excitor nerve sedation to nervous system in producing the process of neurotransmitter.

3, vitamin E is anti-ageing, and vitamin E can be blocked and old and feeble relevant oxidation chain reaction.Geriatric animals can be eliminated cell lipofuscin such as brain tissue after awarding vitamin E, and can improve skin elasticity, sexual gland atrophy, hypomnesia etc.Can also improve simultaneously the activity of enzyme, strengthen immunologic function, thereby slowed down old and feeble process.

Vitamin E also has the raising immunity of organisms in addition, prevents that cardiovascular and cerebrovascular diseases and tumour from having certain effect.

Be deficient in vitamin E, shortage can influence the big myelin of the third and fourth brain nuclei peripheral nerve and touch prominent pipe, the long nuclear of abr cell, is muscle and retina at last.Therefore the typical neurosigns of TD comprises the strong reaction forfeiture of deep layer, balance with coordinate to change, the weak and disturbance of disturbance of visual field of infantile myasthenia is taken in the concentration that vitamin E can prevent the nerve problems state and can keep normal blood plasma Vitamin E every day.

In addition, TD also can cause cellularity hemolytic anemia, immunocompromised etc.

(4) vitamin D ₃(Vit D ₃), it is the derivative of steroids, has advantages of higher stability.High temperature oxidation resisting in neutral and alkaline solution, acid labile, but destroy at the vitamin D that can make spoiled by rancid oil or fat.Vitamin D has two kinds of existence forms, i.e. vitamin Ds ₂And vitamin D ₃Vitamin D ₂Be that ergocalciferol (Ergocaiciferol) is to be formed through the ultraviolet ray irradiation by the ergosterol that vegetalitas is originated.Vitamin D ₃Be that Vitamin D3 (Cholecalciferol) is to be transformed by the 7-dehydrocholesterol that contains in the humans and animals skin, so vitamin D ₃The title that " sunlight " vitamin is arranged.

Physiological function: vitamin D is one of calcium, the most important regulatory factor of phosphorus metabolism, keeps the normal level of calcium and phosphorus, and this all is essential to all cells activity in normal mineralization of skeleton, contraction of muscle, nerve conduction and the body.So vitamin D is one of the necessary nutrient that earns a bare living.

1, promotion calcium phosphorus absorbs, and keeps the level of blood calcium and phosphorus, and when vitamin D directly promoted calcium, phosphorus absorption, it also can keep neural stable and normal cardiomotility and blood clotting, and these functions utilize calcium relevant with phosphorus with the human body supply.Therefore, vitamin D plays crucial effect aspect human calcium's phosphorus eubolism keeping and regulate.

2, promote bone and dental growth, vitamin D good phosphate level and balance of calcium phosphorus in keeping blood, calcification for bone is a kind of crucial material, the calcification of bone is bad, be not only that prior reason is phosphatic shortage, by the effect of vitamin D because of the Ca supply deficiency, body can fully absorb calcium and phosphorus, promotes bone normal growth and calcification.Bone is the calcium of health and the storage vault of phosphorus, and calcium that stores in the bone and phosphorus, again constantly with blood and tissue in calcium, phosphorus exchanging, make the calcium phosphorus concentration in the blood keep constant.When calcium concentration reduced, the calcium that stores in the bone will discharge, and haemoconcentration is raise.The vitamin D active matter promotes the calcium that stores in the sclerotin to dissolve, so the calcium salt that bone stores is released in the blood through stimulating the activity of osteocyte and osteoclast.Why vitamin D can promote the calcification of newborn sclerotin, is because it can provide the high concentration of calcium and phosphorus in blood, because the metabolic activity of osteocyte utilizes calcium and phosphorus and skeletonization, so newborn sclerotin progressively is tending towards calcification, and the effect of Here it is skeletonization.Vitamin D is also kept in the blood normal amino acid concentration in addition, epidemic prevention disease and help effect such as cell normal differentiation.

Vitamin D deficiency: 1, rickets takes place, influence bone tooth and normal development.Vitamin D deficiency causes body that the absorption of calcium and phosphorus is reduced, calcium level is descended, and for keeping the body calcium level, parathyroid gland discharges parathormone and promotes the bone dissolving, the result is that the cartilaginous tissue in the bone and the calcification of osteoid are suppressed, sclerotin and deliquescing thus.So children's cartilage undue growth, bone is weak softening, easily bending deformation.

3, cause osteoporosis, after people in middle age, owing to the D that is deficient in vitamin causes body the absorptivity of calcium is descended, thereby causes the body calcium deficiency, cause sclerotin to run off in a large number, osteoporosis easily takes place.In addition, diseases such as osteomalacia, myopia also can take place in vitamin D deficiency.

(5) vitamin K ₂(Vit K ₂), vitamin K has three kinds of forms to exist.K ₁And K ₂Be present in food such as greenery and the vegetables, but also synthetic vitamin K of animal intestinal, and the vitamin K synthetic with chemical method is K ₃

Vitamin K is a kind of new fat-soluble active substance.Mainly be present in the green plants, the natural vitamin K that exists has two kinds of forms.Be K ₁And K ₂It is a kind of multi-functional vitamin.

Physiological function: vitamin K can be kept the activity of factor and clotting factor, and is therefore relevant with blood clotting.It is very important that metabolism to calcium is played a part, and studies show that vitamin K promotes the bone metabolism, bone forms with reparation relation; Can prevent osteoporosis.Vitamin K can act on Gegenbaur's cell, promotes the bone tissue calcification, can also suppress osteoclast simultaneously, causes that bone absorbs, thereby increases bone density, not only can prevent from also can treat osteoporosis.

Vitamin K can change grape into the normal function that liver was stored and kept to glycogen in liver.Can prevent enterorrhagia at enteron aisle, and the function of the enteric infection of preventing is arranged.

Be deficient in vitamin K, vitamin K deficiency can cause Hypoprothrombinemia, and other coagulation factors vitamin K dependent concentration descends, and shows as blood coagulation defective and hemorrhage.

(6) vitamin C (Citc) has another name called ascorbic acid, is the natural materials that extensively is present in the fruits and vegetables.Pure vitamin C is the crystallization of white, has tangible tart flavour, and is soluble in water.Vitamin C should not be processed under high temperature and alkali condition.Vitamin C is a kind of simple six carbon compounds, and occurring in nature has two kinds of forms, i.e. reduced form ascorbic acid and oxidized form hydroascorbic acid, and the both has biologically active, and the latter is the former 80%, all can be utilized by body.

Physiological function: 1, vitamin C participates in biosynthesis, the cofactors as substrate and enzyme participates in multiple important biosynthetic process in the digestion process in vivo, comprise collagen, carnitine, the metabolism of the synthetic and tyrosine of its this neurotransmitter and peptide hormone etc.Some enzyme require vitamin C just can be kept the activity of height.Vitamin C has the reproducibility of height, therefore has anti-oxidation function.It may reduce superoxides, hydroxyl, hypochlorous acid and other activating oxide and other antioxidant for clearing free radical, blocking-up lipid peroxidation.Vitamin C can make calcium ion maintenance dissolved state in the enteron aisle as a kind of acid medium, thereby helps the absorption of calcium.As a kind of reducing agent, vitamin C can make the ferrous ion that is difficult to absorb be reduced into ferric ion, promotes the absorption of enteron aisle to iron, and vitamin C can also increase the activity of some iron enzyme in vivo, thereby helps the utilization of iron.Therefore hypoferric anemia, except ferrous preparation, also must taking vitamin C simultaneously, to mend the iron effect just more obvious.Vitamin C promotes bone and dental growth in addition in addition.

2, improve brain function: vitamin C can improve the permeability of the very thin neural pipeline of cerebral tissue neuron kind, make to brain and carry essential nutrients unimpeded, promote the brain vigor and improve cerebral function, improve children's intelligence and memory, alleviate psychological pressure, quiet mood.Vitamin C concentration becomes positive correlation in American Studies finder's IQ and the blood.

Vitamin C also has the cholesterol of reduction, reducing blood lipid except above-mentioned functions, prevention of arterial is atherosis, safeguards health of heart, improves immunity of organisms, and preventing cold is kept skin health, skin whitening, the anti-ageing function of waiting for a long time.

Be deficient in vitamin C:1, hypovitaminosis C nerve channel changes easily, causes function of brain cell to reduce, and causes decrease of memory, and be slow in reacting, even cerebral agenesis.

2, because vitamin C and collagen compositive relation are close, thus in the scorbutic pathological change that hypovitaminosis C drew main intercellular connective tissue, the especially collagen as growing bone, tooth and blood vessel etc.Pathology in bone mainly is to cause the bone poor growth, and cartilage matrix is calcification etc. normally.

Hypovitaminosis C can cause that also the scurvy symptom is a dental haemorrhage in addition, tired DOMS, dry skin, symptom such as coarse.

(7) Cobastab ₁(Vit B1) has another name called thiamine (Thiamin).Anti beriberi vitamin and aneurine.Being one of human discovery vitamin the earliest, is a kind of water soluble vitamin, is insoluble to fat and fat-soluble.Vitamin B1 is stable to light, oxygen and acid, and heating is difficult for decomposing, and is not alkaline-resisting.

Physiological function: 1, Cobastab ₁With hydroxylase, the effect of in the coenzyme involved in sugar metabolism of transketolase two reaction 2-ketoacid oxidation deshydroxies, promptly pyruvic acid transfers acetyl-COA to and KG transfers butanedioic acid COA to; The commentaries on classics ketone group enzyme reaction of pentose phosphate pathway, activity has regulating action to nervous physiology, is highly profitable to keeping good memory to alleviate brain fatigue, and the normal function of the muscle digestive system and the circulatory system promotes that appetite also has effect.

2, promote the brain function: Cobastab ₁Content can promote the nerve fiber glycometabolism to increase energy apparently higher than other organ in brain.Cobastab ₁Be spirituality vitamin, this is because Cobastab ₁Nerve fiber and spiritual shape there is desirable influence, nutritious nerve, the effect that improves nervous function.

Cobastab ₁Lack: B is deficient in vitamin ₁Can cause athlete's foot, 1, dry beriberi is the B that is deficient in vitamin in the humans and animals body ₁Final consequence, he mainly influences cardiovascular and the optic nerve system.This thing is based on neurological symptom, occurs irritatedly, and the state of mind is poor, the brain function also have in various degree reduction, forgetful, energy is not concentrated, dreaminess, symptom such as suspicious, occurs peripheral nerve inflammation shape after a while, myalgia and press painfully, especially diseased flesh is for very.

2, beriberi humida, this disease be based on the cardiovascular system symptom, mainly shows as movable back palpitaition, and be rough, and heart enlarges and noise and oedema etc. are arranged.Cobastab ₁Shortage is accumulated intermediate products such as pyruvic acid, lactic acid in brain tissue, a series of symptoms of nervous breakdown can occur, anorexia, malaise, agitation, anxiety, thought slowness, hypomnesia.

(8), Cobastab ₂(Vit B ₂), having another name called riboflavin (Riboflavin) is a kind of water miscible vitamin.Be orange-yellow crystallization, little bitter.To thermally-stabilised, responsive to alkalescence and light ratio, the ultraviolet ray irradiation very easily makes its destruction in the acid solution.Cobastab ₂Mainly function is the prothetic group that constitutes flavo-enzyme with the form of examining yellow mononucleotide (FMN) and flavin adenine dinucleotide (FAD) (FAD) in vivo.

Physiological function: 1, Cobastab ₂Participate in metabolism in vivo, Cobastab ₂Be growth promoter, play promote to grow, vision protection, dimension expand skin health, strengthen effects such as body is anti-oxidant.

2, Cobastab ₂Relevant with the absorption storage of iron, in preventing hypoferric anemia, play an important role.Cobastab ₂Activate tryptophan in addition, participate in tryptophan and form niacin and biological oxidation process.Cobastab in addition ₂Also have diuresis, detumescence, reducing blood lipid, anticancer and improve effects such as heart function.

B is deficient in vitamin ₂: Cobastab ₂Shortage can cause growth disorder, riboflavin is by body health and grow necessary, the coenzyme of its formation is the indispensable component parts of many oxidizing ferment, in biological oxidation process, participate in the transmission of hydrogen, promote the metabolism of protein, fat, carbohydrate, long-term lacking can cause growthretardation, influence the absorption and the storage of iron, because iron is neuronic important component, iron deficiency causes tangible dysnoesia, descends the sense of hearing and vision system infringement as learning ability, linguistic function is low, so Cobastab ₂Lack remote-effects children's intelligence development.

(9), Cobastab ₆(Vit B ₆) have another name called pyridoxol, comprise pyridoxine, pyridoxal and the pyrrole three kinds of activity forms of ammonia of trembling.Cobastab ₆To heat, acid, oxygen is comparatively stable, not alkaline-resisting, in neutral and alkali environment, easily destroyed by ultraviolet ray.

Physiological function: Cobastab ₆Coenzyme composition for plurality of enzymes in the body participates in a series of bioconversion reaction, and is very close, especially very important to the metabolism of protein with three major nutrient metabolism relation.Cobastab ₆Be the biosynthetic coenzyme of neurotransmitter.For example: the formation of some neurotransmitters, tryptophan transform to generate nicotinic acid, and linoleic acid changes into arachidonic acid etc. needs Cobastab ₆Participation. In the nervous system in the metabolic process of many neurotransmitters such as 5-hydroxyl look ammonia, Taurine, dopamine etc. enzymatic reaction need the participation of phosphopyridoxal pyridoxal phosphate.Cobastab ₆Also have the conversion that helps brain and nerve cell self-energy, thereby strengthen the curative effect of levodopa; And stimulate hemoglobin to produce; Keep the balance of potassium, sodium, chlorine.All cells regeneration and normal growth, essential by keeping normal brain function nervous system activity, synthetic at nucleic acid, function of immune system, production of antibodies plays the coenzyme effect.

In addition, Cobastab ₆Also have the reduction serum cholesterol, AFL improves immunity of organisms, prevents coronary heart disease, multiple functions such as hypertension and cancer.

B is deficient in vitamin ₆: because Cobastab ₆Participate in the metabolic process of multiple material, cause dysbolism, corresponding symptom and disease can occur, the easy irriate of nervous system once lack; Suppress mentally deranged etc., the children B that is deficient in vitamin ₆Stop growing after a few days, and agitation, jerk, vomiting, diarrhoea etc. can occur.

(10) Cobastab ₁₂(Vit B ₁₂) Cobastab ₁₂Being the most complicated a kind of of vitamin molecules max architecture, because of containing cobalt in the molecule, being called cobalt element again, is unique vitamin that contains mineral matter.

Cobastab ₁₂Be present in animal food, as liver, kidney, goods content is also abundant, Cobastab ₁₂Soluble in water and ethanol, the most stable under the PH4.5-PH5.0 mild acid conditions, strong acid, highly basic are unstable under illumination, are subject to metal, strong oxidizer effect and destroying.

Physiological function: 1, Cobastab ₁₂Major physiological function in human body is to improve the utilization rate of folic acid and the aggregate velocity of nucleic acid and protein, promote cell development with ripe, safeguard the metabolic function of neural marrow, participate in the building-up process of acetylcholine, help to focus one's attention on, strengthen memory.

2, prevention anaemia, Cobastab ₁₂Participate in many biochemical reactions in the body as coenzyme, regulate erythrocytic formation with folic acid.Promote the utilization of iron.The food normal stool, absorb, protein synthetic, the metabolism of carbohydrate all needs Cobastab ₁₂

Cobastab ₁₂Lack: B is deficient in vitamin ₁₂Can cause anaemia, mental retardation, failure of memory, emotional, spirit suppresses, and produces multiple diseases such as confirmed fatigue.

(11) folic acid (Folacinfa), claims pteroic acid acyl glutamic acid again, by the dish pyridine Oxybenzene formic acid and glutamic acid is become to be grouped into for three kinds.Naturally occurring folic acid mostly has a plurality of glutamic acid, and biologically active form is tetrahydrofolic acid (THFA).Folic acid is distributed widely in nature, and folic acid is the abundant a kind of material of content in the plant greenery, so name folic acid is yellow crystal, and soluble in water and ethanol, unstable in acid solution.

Physiological function: folic acid is to protein, nucleic acid, and the synthetic of amino acid and neurotransmitter is essential, and normal cell is formed with facilitation, and each cell growth all needs the participation of folic acid.Also generate relevant to red blood cell.Enough folic acid has important meaning to guaranteeing children's cell proliferation and growth.

Someone claims that folic acid is brain food, because it and nervous system development have substantial connection, it can help the generation and the erythrocytic formation of energy, so can strengthen immunologic function.

Folic acid deficiency: lack folic acid and cause in the marrow of function, can not be ripe to inmature red blood cell, the level of hemoglobin descends, and leucocyte, platelet levels descend simultaneously, thereby cause pernicious anaemia, i.e. megaloblastic anemia.Human body fatigue can occur because of anaemia, expiratory dyspnea, symptoms such as cardiovascular, dull-witted, oedema, the ability reduction of the anti-external disease of human body simultaneously.

In addition during folic acid deficiency, normal spiritedness is weak, forgetful, depressed, insomnia, agitation, nac protein are obstructed, and can cause childhood dystrophy and growth retardation.

(12) nicotinic acid (Nicotinicacid) has another name called niacin, nicotinic acid, the anti-leprosy skin factor.The main in vivo niacinamide form with physiologically active exists, and nicotinic acid has very high stability, and is survivable under acid, alkali, light and heating condition, belongs in all vitamins the most stable, water-soluble.

Physiological function: nicotinic acid is the coenzyme of 200 plurality of enzymes in the body, and participates in the production capacity process of three big production capacity nutrients, promotes the brain trophic component, safeguards nervous system, the normal function of digestive system and skin.Nicotinic acid also has the reduction serum cholesterol, expands not blood vessel slightly, at cranial nerve function, and aspects such as drug metabolism, nicotinic acid is being played the part of crucial role.If there is not sufficient nicotinic acid, a lot of important food process all will delay and stop in the body, and energy supply descends, and the people is tired easily, this shows that nicotinic acid is the indispensable vitamin of the heavy modern of pressure.Nicotinic acid also has certain beautification function in addition, it and vitamin A and Cobastab ₂Identical, the effect of the mucous membrane of skin care is all arranged.In case this biostearin picked-up is not enough, skin can take place to the phenomenon of angling, also stomatitis and whelk can occur simultaneously.

Nicotinic acid deficiency: nicotinic acid shows as weak and feeble when slightly lacking, burnout, body weight decline, apocleisis etc.; Skin, alimentary canal and nervous symptoms appear in severe when lacking.The modal sign of nicotinic acid deficiency is skin, neural variation, and wherein skin symptom is the most outstanding, and neurological symptom mainly contains depression, headache, fatigue, ameleia and has a lapse of memory, and long-term lacking can cause significant amentia.

(13), biotin (Biotin) have another name called biotin, biotin.Biotin extensively is present in the various foods, and the bacterium of human gastrointestinal tract also can synthesizing biotinylated.Biotin is a kind of white crystals powder, and is water-soluble, its dry powder quite stable, but unstable in solution.

Physiological function: like huge, complicated, a senior biochemical processing factory, various important chemical reactions are all taking place every day, and these chemical reactions need various enzymes to play catalytic action in the human body, run well to guarantee body.And biotin is exactly the essential confactor of some important enzymes in the human body, and during egg-white injury, the activity of these enzymes will descend, and some important chemical reactions and metabolic activity are affected thereupon in the human body.Biotin participates in the important physiological activity of human body, comprises that the generation of cell growth, lipid, sugar and amino acid metabolism and energy, glycogen generate, the biosynthesis of genetic stew-DNA, various immunocyte normal operations.Biotin still is that body growth is grown indispensable essential nutrients.

In addition, biotin can help the healthy and normal growth of hair, skin, marrow and body of gland, and biotin is to the treatment white hair and prevent that bald head from having certain effect.

Egg-white injury: it is manic, drowsiness and growth retardation that children lack the most serious nervous symptoms of biotin.

(14), calcium (Ca) calcium are the multifunctional and nutritional element, are the important component that human body constitutes, 2% of about percentage of liveweight, and wherein 99% exists in bone and the tooth.Calcium is not only and is constituted the indispensable part of body integrality, and body growth grow and physiological and biochemical procedure in play important effect to earning a bare living.

Physiological function: 1, form and keep bone and tooth structure, calcium mainly rises and presides over and protective effect in bone and the tooth, forms miscible calcium pool, keep the concentration of blood plasma constant relatively, and the calcium in the miscible calcium pool constantly is deposited on Gegenbaur's cell.Bone is influential to height to be exactly vertebrae and pin bone.And calcium is the important element that constitutes bone, and skeletal growth is grown crucial effects, and the bone growth and development of children and youth is quickened, and bone mineral content is to reach best peak bone mass in the raising bone.

2, keep the excitement of N﹠M, regulate heart.Calcium is relevant with the contraction and the diastole of muscle, and when the calcium solubility in the blood reduced, the excitability of N﹠M increased, the spontaneous contraction appears in muscle, can have a convulsion when serious, and the excitability of N﹠M increases when calcium concentration in the blood increases, then the N﹠M excitability reduces.

, activate plurality of enzymes: calcium can activate adenosinetriphosphataes,, lipase, protease and amylase etc., and be the requisite composition of amylase activity.

4, calcium participates in the synthetic of interior multiple hormone of body and neurotransmitter, regulates endocrine, strengthens the body immunity function, keeps the normal permeability of normal blood pressure and blood vessel etc.

Calcium deficiency: children's calcium deficiency is often followed protein and vitamin D deficiency, can cause growth retardation, new abnormal bone structure, and bone calcification is bad, and rickets takes place in textured bone.Asthenopia and dispersion attention appear in calcium deficiency easily, MR, and the brain response ability, multiple diseases such as adult's hypertension and senile osteoporosis, what is more important causes early ageing.

(15), zinc (Zn), zinc are one of trace elements of wanting of body weight for humans, and zinc mainly is present in the organs such as bone, tooth, skin, muscle, especially with retina, choroid, prostate for the highest.

Physiological function: 1, promote to grow: zinc participates in the synthetic of collagen, nucleic acid and protein; And each process of the growth of pair cell and regeneration, division and molecule all is essential.Therefore, zinc all is very important trace element to children, the teenager who is in the animated period that grows.Zinc has important meaning in skeleton development, metabolism; Zinc can promote cell proliferation and differentiation, and low zinc can cause the bone center slow sclerotin attenuation to occur, and bone density reduces, and the bone profile shows as and vitamin D ₃The bone calcification obstacle is similar due to the shortage.Growth attenuation broadening only has faint temporary calcification, and calcium content of bone reduces.

2, promote brain growth: the height of zinc content is tangible positive correlation with learning and memory.Zinc mainly is combined on the brain cell membrane, energy activating phosphatase pyridoxal synzyme and inhibition y-aminobutyric acid (GABA) synzyme, thus reduce the synthetic of inhibition central neurotransmitter y-aminobutyric acid.Zinc is being regulated neuronic y-aminobutyric acid concentration performance key effect, and particularly human brain hippocampus zinc concentration is higher, and hippocampus is the important nuclear group of learning and memory, therefore, influences learning and memory thereby lack the eubolism that influences the cerebral hippocampal district behind the zinc.University research of the U.S. finds that zinc content is all than fathead height in the clever children and youth body of succeeding in school.

3, strengthen immunity: zinc is in close relations with immunologic function, can impel atrophy of thymus gland as lacking, and the thymosin extrasin secretion reduces the weight saving of spleen etc.The T cell quantity reduces, and antibody production descends, lymphocytophthisis, and the neutrophil leucocyte chemotactic is suppressed, thereby causes Abwehrkraft des Koepers to descend, and function of immune system goes down.

Zinc deficiency: cause deficiencies such as nucleic acid owing to lack zinc, cause upgrowth and development of children influenced, skeleton development obstacle, the short and small length of health are not high, and reproductive development is bad.Scarce zinc also can cause the decline of human body resistance against diseases, immunologic hypofunction, baryencephalia, multiple disease such as prematurely senile.

(16), iron (Fe), iron are the maximum a kind of trace elements of people's in-vivo content; Total amount is about 4 grams-5 grams in vivo, and wherein 60%-70% is with hemoglobin, and 3% with myoglobins, and 1% situation with iron enzyme exists, and all the other 30% exists with the form of stocking iron.Stocking iron mainly is present in the netted pork skin system of liver, spleen and bone with the form of ferritin.

Physiological function: iron mainly is transhipment and the exchange process that the composition that constitutes hemoglobin and myogen participates in oxygen and carbon dioxide in the tissue in human body.

1, participate in the formation of enzyme: iron participates in constituting some metalloenzyme or the confactor that activates some enzyme metalloenzyme, transports in vivo in the transmission of oxygen and endocellular electricity to play an important role.There are more than ten kind of iron enzyme or iron to rely on enzyme in the present known body.Oxidation as atriphos in the mitochondria (ATP) generates the effect that just comprises many iron enzymes, and these enzymes pass through the oxidation of process iron in respiratory chain and reduce alternately, and the function of conveying electronic and storage power is arranged; And catalase, peroxidase, monoamine oxidase etc. all participate in the many metabolic processes of body (DNA is synthetic, catecholamine metabolism etc.).

2, iron is to the influence of nerve: (1) is to the influence of monoamine oxidase (MAO), TPH and aldehyde oxidase etc., the brain tissue monoamine oxidase is that a kind of iron relies on enzyme, energy deactivation monoamine neurotransmitter, organize iron to reduce, can influence the activity of MAO, cause the monoamine neurotransmitter dysbolism; Iron still is the confactor of TPH and aldehyde oxidase, if iron deficiency can influence the synthetic of serotonin and dopamine respectively.

(2) influence the transmission of mitochondria electronics, thereby influence energetic supersession, the quantity of cell mitochondrial gathering iron how much, influences body self-energy and release, and it is many more to assemble iron, and the energy of release is just many more; And, enzyme over half in the tri hydroxy acid circulation (citrate cycle) and confactor contains iron or competence exertion physiological function when iron exists, therefore iron deficiency can cause multiple metabolic disorders such as the transportation of the transportation of oxygen and storage, carbon dioxide and release, electronics transmission, redox, produces pathological change.Iron is the important component of hemoglobin in the red blood cell, and the normal physiological activity of brain had both needed blood that oxygen is provided, and needs again that a whole set of biological oxidation enzyme carries out catalysis in the brain tissue cell.Many biological oxidation enzymes belong to iron content egg enzyme, and they are the most responsive to iron deficiency.

3, influence myelinic generation, the conduction of infringement nervous system signal, iron in the oligodendroglia participates in the metabolism of myelin, comprise the synthetic of cholesterol fat acid, and iron deficiency can influence the protein level rising, suppress the expression of galactocerebroside, cause nervous system myelinization deficiency, the neuronal signal conduction is obstructed.Early iron deficiency anemia is for many years sustainable to children's The Long-term Effect.Between anaemia children and contrast experimenter, their study performance, sensation, locomitivity, notice, learning and memory exist difference.

In addition, iron is kept the normal immunity of body and is also had certain effect control brainfag and forgetful.

Asiderosis: iron deficiency can cause Iron deficiency anemia in children, is that red blood cell reduces, and color is thin out; Muscle protein also contains irony, and iron deficiency makes physical efficiency descend the locomitivity variation; Irony also exists in the cytochromes, participates in the metabolism reaction, regulates the whole organ physiological activity knifeedge.Iron deficiency can constitute influence to brain, the iron enzyme in the brain cell is descended, and then influence cellular oxidation metabolic response and nerve conduction material, and the result causes abnormal behavior, and feeblemindedness is absent minded, symptoms such as poor memory.

(17) phosphorus (P) is one of more element of body burden, is the 6th inferior to calcium slightly, accounts for 1% of body weight for humans, and it does not still constitute the composition of human body, and participates in very important metabolic process in the vital movement.

Physiological function: 1, phosphorus is the important source material that constitutes bone and tooth.Human body bone phosphorus accounts for 85% of total phosphorus, is half of bone calcium.Phosphorus also is to constitute cell, as the constituent of nucleic acid, protein, phosphoric acid and coenzyme, participates in very important metabolic process.

2, phosphorus participates in constituting energy supply, ergastic substances such as atriphos (ATP), phosphocreatine, plays a major role in energy generation, reversal procedures.

3, phosphorus participates in the synthetic of nucleic acid, and participates in the metabolism of nucleic acid.Many coenzyme all have the participation of phosphorus.As diphosphothiamine, phosphopyridoxal pyridoxal phosphate, coenzyme.Phosphate is formed buffer system, can keep the acid-base balance of body fluid, and blood pH is maintained in the normal scope, so that keep stable and metabolic activity normal of organismic internal environment.

Phosphorus lacks: hypophosphatemia can take place in scarce phosphorus, and its influence comprises that skeleton development is bad, growth retardation, apocleisis, anaemia, myasthenia, rickets and cartilaginification, amentia etc.

(18), magnesium (MG), magnesium is human essential elements, and human body contains 20-30 gram, and wherein 70% is the composition that constitutes bone and tooth, and 25% is present in the soft tissue, and all the other 5% exist in the body fluid.Magnesium is to be only second to potassium second polycation in the cell.300 plurality of enzymes activity need the participation of magnesium in the human body.

Physiological function: 1, magnesium is one of important component that constitutes on bone, has the function of the bone hardness kept, intensity and durability.

2, magnesium can improve memory: mineral matter magnesium is the essential element of regulating brain learning and memory function.Especially for the elderly, magnesium is not only to the structure of bone, the adjusting of body temperature, the formation of protein, and the energy that discharges muscle is very big, and more to brain is anti-ageing positive role is arranged.

3, protect the cardiovascular factor: magnesium is essential by safeguarding the heart normal function, participate in multiple biochemical metabolism reaction in the body, and magnesium and angiocardiopathy relation is very close.Epidemiology survey proves, the area that China's soil magnesium content is high, and the incidence of disease of the hypertension among the crowd, heart disease and cancer is very low.Magnesium can make the external perihaemal canal resistance descend, and suppresses the contraction of vascular smooth muscle, makes vasodilation, blood pressure drops.Prevent the calmness of cholesterol on the arterial blood tube wall, artery sclerosis and coronary heart disease are had good preventive and therapeutic effect.

Magnesium lacks: chronic deficiency magnesium is correlated with modesty heart disease, hypertension, cerebrovascular disorder.Noticeable is that the magnesium insufficiency of intake has become the reason that current heart disease sharply increases.Known severe magnesium lacks to cause and is called neuroticism, phrenoblabias such as neurological disorder and melancholia uneasiness, and many symptoms lack relevant with magnesium.Magnesium is also referred to as relevant with osteoporosis.Relevant research report points out, picked-up and Mg supplementation can relax bone density and vertebrae is crooked not just.Magnesium deficiency can influence the release of nervous centralis medium, and platelet aggregation and cerebral cortex suppress to increase the weight of.

(19), potassium (K), one of cation of wanting for body weight for humans is the essential element of intracellular fluid, also is one of extracellular fluid important component.Normal person's total body kalium is 50mmOl/kg.Potassium mainly is present in the cell, accounts for 98% of total amount, and other is present in the extracellular.

Physiological function: 1, keep myocardial function, potassium is extremely important to myocardial nutrition, and its collaborative calcium and magnesium are kept the heart normal function, keep self-disciplining, conductibility and the excitability of cardiac muscle.

2, participate in metabolism, cellular metabolism will have the participation of potassium, the glucose glycogen biosynthesis, and amino acid synthesizes myogen, and adenosine diphosphate is transformed into adenosine triphosphate all needs potassium.

3, keep osmotic pressure: cell and potassium and extracellular sodium interact, condition each other, and keep the inside and outside potassium of cell, sodium ion ratio, are the key factors of keeping relative osmotic pressure.

4, keep the muscle normal function: potassium can activate meat fiber and shrink, and causes the nerve synapse release neurotransmitters, keeps nervimuscular normal function.

5, hypotensive activity: potassium can keep suitably alkaline in the body, helps skin health, keeps acid-base balance.Potassium to improve water, sodium retention, makes blood pressure drops by diuresis, hemangiectasis etc.

Potassium deficiency: lacking potassium can take place functional or pathologic changes in systems such as neuromuscular, digestion, cardiovascular, uropoiesis, nervous centralis.Mainly show as multiple diseases such as myasthenia, arrhythmia cordis and renal dysfunction.

(20), iodine (I), iodine is the trace element of needed by human, is the important component of synthetic thyroid.Human body includes iodine 15-20 milligram, and wherein there is thyroid gland in 70%-80%.

Iodine is the important source material of thyroid hormone, and all biological actions of thyroid gland and iodine have direct relation.

Physiological function: 1, the influence to growing: trace iodine is the main component of thyroid hormone, and it is metabolism and the growth and development process that promotes material and energy that thyroxine mainly acts on.Thyroid gland mainly influences the growth and the growth of brain and long bone.Particularly be born and had the greatest impact in back 4 months; The formation of nerve cell, the growth of myelin and spongiocyte, neural generation and development, and the supply of blood flow of brain helps through by thyroid hormone.Iodine is that to keep human body normal development institute indispensable.Zoopery finds that thyroid hormone that must be enough exists, the growth hormone competence exertion effect of pituitary secretion.And thyroid hormone can promote protein synthetic, promotes the absorption and the utilization of vitamin, activates multiple important enzyme, and this is very important to growing of children's height, body weight, bone, muscle etc.

2, to neural influence: iodine is brain development and the essential trace element of keeping brain function.The neurochemistry function of iodine mainly works by special acceptor.In the critical period of brain growth, nervous system development must rely on thyroxinic existence.Neuron propagation, migration, differentiation and myelinization, owing to dendron, dendritic spines, the foundation of cynapse and nerve connections all needs the participation of thyroid hormone, and brain also has special requirement to iodine, to keep the normal function of brain.

In addition, iodine can promote protein, carbohydrate, fat to change into the effect of energetic supersession.Improve the oxygen demand of tissue, increase heat production, promote hepatic glycogen to decompose, promote the generation of protein and various enzymes.

Iodine deficiency: 1, gram is ordered disease.When iodine deficiency, thyroid hormone is synthetic to be reduced, and is that these processes can not be carried out, and the harm of iodine maximum is brain growth, and brain growth is very responsive to the shortage of trophic factor and hormone.Thyroid hormone has strict timeliness to brain growth, be the brain growth critical period, at this moment iodine deficiency can cause brain growth in various degree to fall behind feeblemindedness, blunt, of short and small stature, limbs chap, tooth development is incomplete, grows slow, deaf and dumb or aphasis.

2, thyroid gland enlargement: when the body iodine deficiency, the synthetic reduction of thyroid hormone, TSH of pituitary secretion in feedback ground increases, and long-term TSH too much secretes parathyroid tissue hyperplasia, causes the thyroid gland enlargement.

(20) copper (Cu), copper is distributed widely in the biological tissue, and big portion exists with organic double compound, much is metalloprotein, plays function with the form of enzyme.Copper also is the indispensable trace element of human health.Copper in the body is distributed in histoorgan, and wherein muscle and bone content are maximum, and is the highest with brain and liver concentration.

Physiological function: 1, promote connective tissue synthetic, perfect bone, vascular wall, the collagen of knot tellurium tissue, elastin laminin is synthetic to be needed by copper enzyme-bad oxidase catalyzed cross-linking reaction of acyl aminoacyl, thereby form the covalent cross-linking structure in elastomer and the collagenous fibres, keep and organize toughness and elasticity, therefore, copper is in formation, the bone mineralising of skin and bone, and the connective tissue of heart and vascular system plays an important role in improving.

2, safeguard normal hematopoiesis function: metabolism and cell that copper participates in iron generate.CER claims ferrous oxidase again ¹, synthetic by liver, oxidable iron ion, catalysis Fe ²⁺Become Fe ³⁺, make it to be incorporated in the blood and transport with transferrin, iron is transported to red blood cell generation point from small intestinal lumen and storing spot, promote hemoglobin synthetic, so the intestinal mucosa cell is absorbed iron to CER and hematopoietic tissue utilizes iron all to play an important role.

3, safeguard central nervous system normal configuration function: copper plays multiple effect in nervous system.The synthetic cell plain color oxidizing ferment effect that cupric need be arranged of neurospongium sphingomyelins; Dopamine and the monoamine oxidase relevant with the neurotransmitter catecholamine metabolism are copper enzyme.

Copper lacks: 1, lack the copper anaemia: metabolism and red blood cell that copper participates in iron generate, and red blood cell generates and is subjected to obstacle when lacking copper, and anaemia in various degree can take place.

2, copper lacks and can cause that various copper enzymes are active and descend that descend as the lysyloxidase vigor, elastin laminin and collagen are synthetic to be reduced, and makes the intensity reduction of heart and vascular system tissue even break, and causes death.

3, other: be also shown in pigment when lacking copper and disappear, neurally change sugar tolerance decline, arthritis, cardiac arrhythmia etc.

(21), manganese (Mn), manganese is very important trace element in the human body, participates in multiple physiological activity in vivo, and health is played an important role.

Physiological function: in recent years, manganese element is quite favored, it and protein, nucleic acid synthetic, and insulin generates secretion, the synthetic conversion of sex hormone, multinomial mental functionings such as the removing of interior free yl and ambient stable are in close relations.Manganese not only promotes the normal development of skeleton, also can keep normal brain function.

Manganese deficiency: the major reason that manganese deficiency can cause osteoporosis and easily take place to fracture in body, skeleton deformity can appear in manganese deficiency, and cartilage is impaired, and growth retardation appears in children.The harm of children's maximum is to disturb the brain function of bringing into normal play, and causes tangible intelligence to descend ADD.In addition, manganese deficiency also can cause disorders of lipid metabolism, and the endocrine function imbalance causes atherosclerotic, heart change, high cholesterol, symptoms such as hypertension.

(22), perilla herb oil: perilla herb oil is the natural oil that medicine-food two-purpose purple perilla seed extracts.Mainly contain the undersaturated aliphatic acid series of ω-3, be up to (50%-70%) with alpha-linolenic acid content, all the other are linoleic acid (about 15%), compositions such as palmitic acid, stearic acid.

The alpha-linolenic acid of perilla herb oil exists with DHA (DHA) and eicosapentaenoic acid (EPA) form in vivo.Alpha-linolenic acid is the aliphatic acid of human body necessity.Studies confirm that DHA is one of the most basic composition of cerebral nervous system, in the brain cell nerve, play a part to transmit signal that relevant memory, function and thinking all depend on keeping of DHA and improve.The zoopery of relevant report shows, perilla herb oil can promote the synthetic of interior nucleic acid of mouse brain and protein, regulates monoamine neurotransmitter level in the mouse brain, and mouse diving tower number of times is obviously reduced, the lost test of water accuracy obviously improves, and the time that reaches terminal point shortens.And the rat retina albedo is strengthened, the correct response rate that study is tested to brightness discrimination obviously improves, and improves visual performance.The Michel of Britain brain nutrient research institute, the first time of sure saying in the international symposium that nineteen ninety holds in Tokyo in the human brain growth course, needs DHA.Lack senior unrighted acids such as DHA, will cause the obstacle of brain development.

In addition, perilla herb oil also has hypotensive, reducing blood lipid, antithrombotic, antiallergy, anti-inflammatory and effect such as anticancer.

(23), lecithin (Lecithin) are a kind of phosphatide that widely distributes in the animal and plant that exists, and are natural emulsifying agent and nutriment.Lecithin is a kind of general designation, is actually the mixture of being made up of the compound of phosphatid ylcholine (PC is that lecithin accounts for 24%), phosphatidyl-ethanolamine (PE is that cephalin accounts for 25%), phosphatidylinositols (P1 accounts for 33%), serinephosphatide (PS), neural amino alcohol and aliphatic acid, phosphocholine.Since in the phospholipid molecule existing hydrophilic group because of-NH2, NH and-OH, lipophilic group hydrocarbyl chain or saturated and unrighted acid chain R are arranged again.So have the good emulsifying function.

Physiological function: 1, constitute biomembranous main component.Phosphatide is biomembranous main composition part, and biomembranous flowability depends primarily on phosphatide, because hydrophilic, the oleophylic performance of phosphatide make film have permeability, can transport nutriment and enter cell, gets rid of metabolic waste simultaneously.Human body has only the phosphatide that keeps sufficient, could strengthen cytoactive, keeps sufficient energy, improves immunity.

2, brain cell transmits the active material of information, and the metabolite of phosphatide is an acetylcholine, and acetylcholine participates in the information transmission of nerve cell, the cerebral nerve information transmission speed is accelerated, strengthen memory, thinking and analysis ability, allow the people become clever, promote cranial nerve cynapse prosperity to get up.

3, brain is built in intelligence development: lecithin can activate brain cell and improve memory and notice.Lecithin hydrolysis in human body generates choline, glycerophosphatide and aliphatic acid; Have very strong physiologically active and nutritive value, can improve neurochemistry function and cerebral function, slow down the degeneration of brain cell, the raising memory of building up health.U.S. scientist studies show that lecithin is the indispensable nutrient of brain cell, zoopery, and memory and capacity can improve 20%-25%.

4, the bioactivator of synthetic fat protein metabolism fat: the choline in the phosphatide affects the metabolism of fat, and lecithin can promote fat metabolism, if human body choline deficiency then forms fatty liver easily.Phosphatid ylcholine is the necessary material of synthetic fat albumen, and after phosphatide entered human body, synthesizing of subparticipation HDL (HDL) suitably replenished the formation that phosphatide both can prevent fatty liver, can impel liver cell regeneration again.In addition, phosphatide also has reducing blood lipid, multiple function such as delay senility.

(24), Taurine: Taurine is two carbon unstructuredness sulfur-containing amino acid, claims the alpha-amido ethyl sulfonic acid again.Synthesize by deshydroxy carboxylic, oxidation by methionine, cysteine in vivo.Be prevalent in the interior liquid of each histocyte of animal.Taurine does not participate in the synthetic of protein.Be a kind of condition essential amino acid, contain abundant Taurine in the brain tissue.Taurine has the brain of keeping nutrition, regulates nerve conduction, promotes brain development, increases intelligence, improves ability of learning and memory; Useful to the retina normal development, strengthen and improve eyesight, alleviate visual fatigue; Reducing blood lipid, hypotensive; Protect myocardium irritability damage; The antibiont peroxidating with delay senility.Recent study finds that Taurine can improve body internal specific and non-characteristic immunologic function, promotes the T lymphocyte to produce interleukin 1, strengthens neutrophil leucocyte and engulfs bactericidal activity, and infant's immune cell defense function is played an important role.

Studies confirm that the infant lacks Taurine, the disorderly and growth of retinal function can take place, MR.The Taurine shortage can have influence on growth, eyesight, heart and brain in a word.

(25), L-arginine: be people's concrete conditions in the establishment of a specific crime essential amino acid, it is the precursor that synthetic carbon monoxide, creatine, polyamines, ornithine, proline, glutamate etc. have the material of important physiological function, and the hypophysis of stimulation secretion growth hormone (HGH) is arranged, promote children growth.Arginine is to tissue growth and keep normal physiological function important effect is arranged.

Physiological function: 1, strengthen memory: 1998, three United States Medicine experts obtained this Nobel Prize because of finding relevant arginic important physiological function in year.Scientific payoffs shows that arginine has the brain cell of adjusting flow, and functions such as protection cell membrane, alleviation brain tense situation, enhancing memory are described as " brain grain ".Lack arginine person long-term memory, permanent memory and recite ability and all can weaken.Therefore middle and primary schools survive can influence achievement, even brainfag occurs, the cerebral anoxia phenomenon, and therefore, arginine has the memory of enhancing and the promotion function of growing.

2, promote bone growth: arginine promotes protein to synthesize and growth hormone secretion, is that " hypothalamus hypophysis sexual gland system " imbalance of yin and yang gets muddled the hierarchy of control and health is short and small, and growth hormone reduces, and is the closed too early and termination of epiphysis.And arginine can stimulate pituitary secretion growth hormone to promote marrow hemopoietic stem cells, cell is generated increase, and the blood that grows required oxygen is provided, and makes skeletal cartilage, and cell division speed obviously improves.In addition, arginine can also promote muscle to increase and reduce fat.

(26), L-glutamic acid: glutamic acid is the highest a kind of free amino acid of mammal brain intensive amount.Glutamic acid is one of effective, the abundantest ammonia source of body, occupies an important position in amino acid metabolism, and participates in brain tissue metabolism, mediates a series of higher nervous activities as central excitation acidic amino acid mediator.Studies show that intracerebral injection glutamic acid has the promotion memory effect, glutamine can be by the function performance regulating action of glutamic acid mediator system to brain as the precursor substance of glutamic acid in the brain.Glutamic acid can allow happy the playing a role freely of brain, can keep the operate as normal of brain.

Glutamine is the neurotransmitter of brain and vertebra excitement, also is the precursor of y-aminobutyric acid (GABA).This monoamino-acid is extremely important in sugar and fat metabolism, and can help potassium to enter brain by blood-brain barrier.Brain can utilize glutamic acid to act as a fuel.Glutamic acid energy absorbed nitrogen atom is removed the toxicity of ammonia, and this is the method for the most important releasing toxicity of brain.It is unusual that glutamic acid can also be treated child behavior, diseases such as mental retardation, muscular atrophy and ulcer.

(27), L-glutamine: glutamine is a kind of neutral amino acid, and it has the terminal acylamino-of an alpha-amido facile hydrolysis.

Glutamine is the abundantest a kind of free amino acid of lactation plasma content; It is the carrier of urea synthetic nitrogen in ammonia synthesis and the liver in the kidney; Be scavenger and the many important substance of biosynthesis such as the nucleic acid and the amino acid whose coenosarc of cell amine; Synthetic at mediator's body protein, the degraded of CKIs matter, stimulating cellular growth, activating immune system, promotion growth hormone secretion, improve brain function, anti-melancholy, protection liver, increase glutathione, alleviate tired, the anti-ageing different physiological roles of waiting for a long time.

Physiological function: 1, increase brain tissue nutrition: glutamine has the effect of promoting the brain cell function.The source investigation result shows: the main avoiding reaction rate of rat in empty shuttle box experiment obviously increases, and the passive escape time shortens, and shows that the learning memory of rat improves.And can promote the children ' s intelligence development of feeblemindedness.

2, protection liver: glutamine has the specific function of protection liver organization.Glutamine can increase the content of alcohol dehydrogenase in the body, thereby decomposes ethanol fast, treatment and prevention alcoholism.

3, antifatigue: glutamine has unique metabolic function and nutritive peculiarity, so glutamine can be used for treating sportsman's syndrome, recovery highly intensive labour or post exercise fatigue.

4, strengthen immunity: lymphocyte is rich in highly active glutaminase, when being subjected to immunostimulation, the activity of its enzyme increases, and experiment shows, glutamine can obviously improve the speed that is integrated into of thymidine, so glutamine is the essential material of lymphopoiesis.Discover that in addition glutamine plays an important role in whole host defense mechanism, and improve anti-infection ability.

(28), L-tryptophan: be essential amino acid, when forming nicotinic acid is essential, and brain utilizes tryptophan to produce serotonin, a kind of essential neurotransmitter, nerve impulse is delivered to another cell from a nerve cell, and can improves sleep.Tryptophan can depression, and can Cure for insomnia with set the mind at rest, the control ADD, alleviate stress with the heart burden.Because strengthening the release of growth hormone, tryptophan helps fat-reducing.Sufficient Cobastab ₆Useful to forming tryptophan, also also useful to forming serotonin.

(29), L-asparatate: be a kind of energy amino acid, in human body, be converted into glucogenic amino acid rapidly, can in metabolism, become the amino acid of sugar.Also being excitatory amino acid, is the excitatory transmitter of nervous centralis, by with corresponding acceptor, in conjunction with participating in the transmission of nervous centralis information.Play an important role at learning and memory, synaptic plasticity and neurodevelopment.Also nervous system and cerebral function vigor there is facilitation.Asparatate can be removed excess of ammonia in the blood, so can protect liver.In addition, that asparatate can also booster immunization ball egg and production of antibodies.

(30), inulin: inulin is the mixture of the levulan that extracts from natural plants jerusalem artichoke stem tuber.Having another name called inulin, is to find one of best water-soluble dietary fiber at present.The inulin absorption that is not decomposed in stomach and intestines can be utilized by beneficial bacterium (Bifidobacterium, lactobacillus) in colon, have whole physiological functions of compound sugar, is extraordinary Oilgosaccharkdes, also is a kind of important fat substitute.

Physiological function: inulin is that a kind of important benefit is given birth to former (being Oilgosaccharkdes), has the function of intestinal canal of improvement, reduces serum cholesterol, functions such as reducing blood lipid, hypotensive, stabilised blood sugar level and fat-reducing.Dietary fiber is not enough or lack and the incidence of disease of modern " ciril disease " has direct relation.

Inulin promotes the absorption of mineral matters such as calcium, magnesium, iron.Scientific research confirms that behind the interpolation inulin, its calcium absorptivity on average increases by 18.2% in the meals.

Cover bitter taste, and give soft feel, when in the sweetener compatibility of high sugariness, the paper bitter taste can fall in inulin, and the disagreeable taste in beany flavor and the other products improves mouthfeel, and generation 20% then can fall in the use amount of sweet taste.

In sum, protein is the important substance basis that brain tissue is grown metabolism, is the main matter of presiding over brain cell excitement and process of inhibition, plays an important role at aspects such as memory, language thinking, motion, nerve conduction.Ferro element is one of main matter that constitutes human body hemoglobin, lacks the physiologically active that ferro element can seriously reduce hemoglobin, influences the supply of nutrition and oxygen in the brain, and calcium ion can promote the brain cell microcirculation, improves cerebral ischemia, anaerobic condition.Zinc strengthens resistance against diseases, improves memory, promotes to grow.Vitamin C can make cerebral function flexibly, sharp, improve children intelligence.The B family vitamin can quicken the nutrition transportation, helps to focus one's attention on and strengthen memory.Vitamin B6 is the biosynthetic coenzyme of neurotransmitter, and cobalamin participates in the building-up process of acetylcholine.Vitamin E also has certain effect to memory.Lecithin is the precursor substance of neurotransmitter acetylcholine, can strengthen memory, thinking and analysis ability, allows the people become clever.Perilla herb oil can be converted into DHA and EPA in vivo to have and promotes nerve conduction and nerve synapse cell to grow, and improves brain reasoning, understanding, judgement and memory capability.Taurine has the brain of keeping nutrition, regulates nerve conduction, promotes brain development, increases intelligence, improves ability of learning and memory.Glutamine, glutamic acid and tryptophan etc. are the main matter of synthesizing y-aminobutyric acid and serotonin in the body.Asparatate participates in the transmission of central nervous system information, plays an important role at learning and memory.

Mineral calcium, phosphorus, magnesium are to constitute the most basic element of bone, and is extremely important to skeletal growth.Zinc is significant in bone development, metabolic process, and zinc can promote cell proliferation and differentiation, makes DHA, the synthetic increase of protein, improves bone density.Potassium, manganese, iodine also are the important component of bone, to promoting bone growth extremely important.Vitamin is that upgrowth and development of children is indispensable, and vitamin A, D, C and B family vitamin are even more important to children's height.Protein, arginine, glutamic acid, glutamine, tryptophan etc. stimulate pituitary secretion growth hormone; Skeletal cartilage cell division speed is obviously improved, promote bone growth.Inulin has the repertoire of Bifidobacterium and dietary fiber, hinders the intestinal toxic material, improves function of intestinal canal, and making into, nutrition digestion absorbs.Therefore, clever your high sour milk tablet has the enhancing brain function, promotes bone growth, improves multiple functions such as memory and growth encourage.

The manufacture craft of this sour milk tablet is:

1, pretreatment of raw material, fresh high-quality milk, purification process after filtration.

2, allotment: earlier with fat-soluble A, vitamin E, vitamin D ₃, vitamin K ₂Be dissolved in the perilla herb oil, then with white sugar, glucose, vitamin C, Cobastab ₁, Cobastab ₂, Cobastab ₆, Cobastab ₁₂, folic acid, nicotinic acid, biotin, calcium lactate, ferrous lactate, zinc gluconate, phosphate, magnesium chloride, manganese sulfate, KI, copper sulphate; lecithin, Taurine, L-arginine, L-tryptophan, L-glutamic acid, L-glutamine, L-asparatate, inulin etc. add together in the fresh milk after purifying and mix; and fully stir, to obtain uniform batch mixes liquid.

3, preheating, homogeneous, sterilization concentrate: after mixed milk mixed liquor is preheating to 60-70 ℃ of homogeneous, be heated to 90-100 ℃ again, after the 5-10 minute sterilization processing, send into and keep about 45 ℃ in the vacuum decker and be concentrated into milk solids thing content 45%.

4, inoculation is sent out and roared: the allotment of (1), leavening, the weight ratio of Bao Jiayali lactobacillus and streptococcus lactis are 1: 3-5.(2), inoculation fermentation, the mixed emulsion after concentrating is cooled to 45 ℃ of leavenings that add 1-3%, remain on 45 ℃ of PH4.5-4.7 and stirred 10 minutes, when fermenting acidity reaches 50-60%, stop fermentation.Form during for fear of spraying and doubt admittedly, add the slow neutralization of 5% alkali lye and make acidity be lower than 55%.

5, spray-drying: use high-pressure spray-drying machine (homogenization pressure 14.7-19.6Mpa) to reach the dual purpose of homogeneous, spraying.The spray tower temperature remains on about 45 ℃, and wherein air intake and temperature of outgoing air are respectively about 100 ℃ and 445 ℃.

6, compressing tablet test package: the sour milk powder after the spray-drying is carried out compressing tablet in tablet press machine, tablet press machine pressure is controlled at 0.3-0.35Mpa and carries out compressing tablet, is up to the standards, and gets formal product after the packing.

It is the process that sour milk for the high-quality of fermenting provides required quality raw materials that preliminary treatment is checked and accepted in the standardization of fresh milk.Allotment mixes, and is the operation that fully mixes after all raw materials in the prescription are dissolved respectively by the physicochemical property of its raw material.The homogeneous sterilization is in order to reduce the microorganism total amount to the process that can not endanger the leavening growth of microorganism.The inoculation fermentation operation is the process of adding leavening in the fresh milk mixed liquor according to a certain percentage.Fermentation procedure is the process that becomes sour milk after fresh milk adds leavening at preference temperature environment bottom fermentation, and this operation is converted into lactic acid with lactose, forms tart flavour and gets liquid yogurt.Spray-drying is that the liquid yogurt that ferments is sent into high-pressure spray-drying machine spray-drying under the temperature, pressure of regulation, becomes the operation of sour milk powder.Sheeting process is the process that the sour milk powder that preceding operation makes is suppressed into sheet under the pressure of regulation.This operation gets the semi-finished product sour milk tablet.Test package is the semi-finished product sour milk tablet that preceding operation is made, and by national standard, through after the assay was approved, packing becomes the process of formal product.

Six, quality standard:

1, physical and chemical index

Protein	??(％)	??28
			Fat	??(％)	??12
Carbohydrate	??(％)	??56
			Alpha-linolenic acid	??(g/100g)	??2.4
Lecithin	??(g/100g)	??3
			Taurine	??(mg/100g)	??200
Arginine	??(g/100g)	??6
			Tryptophan	??(g/100g)	??2
Glutamic acid	??(g/100g)	??1.6
			Glutamine	??(g/100g)	??4
Asparatate	??(g/100g)	??2.4
			Inulin	??(g/100g)	??10
Vitamin A	??(mg/100g)	??1.6
			Vitamin E	??(mg/100g)	??30
Vitamin C	??(mg/100g)	??200
			Vitamin D 3	??(μg/100g)	??20
Vitamin K 2	??(μg/100g)	??150
			Cobastab 1	??(mg/100g)	??5
Cobastab 2	??(mg/100g)	??6
			Cobastab 6	??(mg/100g)	??5
Cobastab 12	??(μg/100g)	??10
			Folic acid	??(μg/100g)	??700
Nicotinic acid	??(mg/100g)	??20
			Biotin	??(μg/100g)	??100

Calcium	??(mg/100g)	??2000
			Iron	??(mg/100g)	??36
Zinc	??(mg/100g)	??30
			Phosphorus	??(mg/100g)	??1420
Magnesium	??(mg/100g)	??500
			Potassium	??(mg/100g)	??1000
Manganese	??(mg/100g)	??4
			Copper	??(μg/100g)	??1000
Iodine	??(μg/100g)	??100

2, instructions of taking: every day three times, each 10-15 gram, the infant reduces by half, and before meals is used

This product contains protein, fat, carbohydrate, alpha-linolenic acid, lecithin, Taurine, amino acid, vitamin, mineral matter and active ingredients such as trace element, inulin; it has the children of enhancing, teenager's brain function; promote bone growth, improve functions such as memory and growth encourage.But also have the sour-sweet fruity of sour milk, slick and sly tasty and refreshing.

Seven, the specific embodiment:

Embodiment: get 90 kilograms of fresh milks, 1 kilogram of white sugar, 2 kilograms of glucose, 2.5 kilograms of leavenings, yeast 50 grams, 0.8 kilogram of perilla herb oil, lecithin 600 grams, Taurine 40 grams, L-tryptophan 400 grams, L-glutamic acid 320 grams, L-glutamine 800 grams, 1.2 kilograms of L-arginine, L-asparatate 480 grams, 2 kilograms of inulin, 2 milligrams of 3-Hydroxyretinols, vitamin E 6 grams, vitamin D ₃4 milligrams, vitamin K ₂0.03 gram, Cobastab ₁2 grams, Cobastab ₂2.4 gram, Cobastab ₆1 gram, Cobastab ₁₂2 milligrams, folic acid 0.14 gram, nicotinic acid 4 grams, vitamin C 40 grams, 20 milligrams of biotins, 3.7 kilograms of calcium lactates, ferrous lactate 48 grams, zinc gluconate 45 grams, phosphate 5.6 grams, magnesium carbonate 800 grams, KI 0.02 gram, copper carbonate 0.08 gram.

The fresh milk standardization is filtered, and purifies preliminary treatment, with fat-soluble A, vitamin E, vitamin D ₃, vitamin K ₂Be dissolved in the perilla herb oil, then with fructose, glucose, inulin, vitamin C, Cobastab ₁, Cobastab ₂, Cobastab ₆, Cobastab ₁₂Folic acid; biotin; nicotinic acid; calcium lactate; ferrous lactate; zinc gluconate; phosphate; magnesium chloride; manganese sulfate; KI; copper sulphate; lecithin; Taurine; tryptophan; glutamic acid; glutamine; arginine; asparatate adds in the milk together; and fully mix emulsion after the allotment and be preheating under 65 ℃ of 16Mpa and the 2.5Mpa pressure and carry out the twin-stage homogeneous; after being heated to 100 ℃ of sterilizations in 5 minutes again; send in the vacuum decker and to keep 45 ℃ to be concentrated into and to contain solid content 45%; emulsion after concentrating is cooled to 45 ℃; the leavening of interpolation 2.5% remains on 45 ℃; PH4.6 stirred 10 minutes; fermenting acidity reaches 55% and stops fermentation; form during for fear of spraying and solidify; the alkali lye of adding 5% slowly neutralization makes acidity be lower than 55%, then the liquid yogurt that ferments is sent into high-pressure spray-drying machine (homogenization pressure 14.7-19.6Mpa) to reach the double action of spraying homogeneous.The spray tower temperature remains on 45 ℃, 100 ℃ of its EATs, and temperature of outgoing air carries out spray-drying for 45 ℃ and becomes sour milk powder.Tablet press machine pressure is controlled at 0.3-0.35Mpa and carries out compressing tablet, and this operation gets the semi-finished product sour milk tablet, by state quality standard be up to the standards the packing after become formal product.

Claims (3)

1. One, fermented milk sheets with auxin is characterized in that:
2. 1, manufacture craft is that the fresh milk standard purifies, and allotment and homogeneous, preheating sterilization are concentrated, inoculation fermentation, spray-drying, compressing tablet test package get product.
3. 2, process conditions be the fresh milk pretreatment process with the high-quality milk standardised, purify after filtration, earlier with fat-soluble, 2 milligrams of 3-Hydroxyretinols, vitamin E 6 grams, vitamin D ₃4 milligrams, vitamin K ₂0.03 gram is dissolved in the perilla herb oil, then with 1 kilogram of white sugar, 2 kilograms of glucose, lecithin 600 grams, Taurine 40 grams, L-tryptophan 400 grams, L-glutamic acid 320 grams, L-glutamine 800 grams, 1.2 kilograms of L-arginine, L-asparatate 480 grams, 2 kilograms of inulin, Cobastab ₁2 grams, Cobastab ₂2.4 gram, Cobastab ₆0.5 gram, Cobastab ₁₂2 milligrams, folic acid 0.14 gram, nicotinic acid 4 grams, vitamin C 40 grams, 20 milligrams of biotins, 3.7 kilograms of calcium lactates, ferrous lactate 48 grams, zinc gluconate 45 grams, magnesium carbonate 800 grams, phosphate 5.6 grams, manganese sulfate 2.6 grams, KI 0.02 gram, copper carbonate 0.8 gram etc. are added in the milk after the purification together, and mix fully.Emulsion is preheating to 60 ℃-70 ℃ behind the mixing preparation, after carrying out the twin-stage homogeneous under 16Mpa and the 2.5Mpa pressure, be heated to 100 ℃ of sterilizations in 5 minutes again, then send in the vacuum decker and to keep 45 ℃ to be concentrated into and to contain solid content 45%, emulsion after concentrating is cooled to 45 ℃, the leavening that adds 1%-3% remains on 45 ℃, and PH4.5-4.7PH stirred 10 minutes, and fermenting acidity reaches 50%-60% and stops fermentation.What form during for fear of spraying solidifies, and the alkali lye of adding 5% slowly neutralization makes acidity be lower than 55%.The liquid yogurt that ferments is sent into high-pressure spray-drying machine (homogenization pressure is 14.7-19.6Mpa) to reach the double action of spraying homogeneous.The spray tower temperature remains on about 45 ℃, 100 ℃ of its EATs, 45 ℃ of temperature of outgoing airs.Compressing tablet pressure is controlled at after 0.3-0.35Mpa carries out compressing tablet, be up to the standards pack formal product.