CN1680325B - 吡啶衍生物的生产方法 - Google Patents

吡啶衍生物的生产方法 Download PDF

Info

Publication number
CN1680325B
CN1680325B CN200510006703.6A CN200510006703A CN1680325B CN 1680325 B CN1680325 B CN 1680325B CN 200510006703 A CN200510006703 A CN 200510006703A CN 1680325 B CN1680325 B CN 1680325B
Authority
CN
China
Prior art keywords
alkyl
mole
expression
acid
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200510006703.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN1680325A (zh
Inventor
桑原博一
张长山
斋藤广满
园田隆之
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Fujifilm Finechemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Finechemicals Co Ltd filed Critical Fujifilm Finechemicals Co Ltd
Publication of CN1680325A publication Critical patent/CN1680325A/zh
Application granted granted Critical
Publication of CN1680325B publication Critical patent/CN1680325B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/08—Preparation by ring-closure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/22—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing two or more pyridine rings directly linked together, e.g. bipyridyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CN200510006703.6A 2004-02-02 2005-02-02 吡啶衍生物的生产方法 Expired - Fee Related CN1680325B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004025806A JP4700916B2 (ja) 2004-02-02 2004-02-02 ピリジン誘導体の製造方法
JP2004-025806 2004-02-02
JP2004025806 2004-02-02

Publications (2)

Publication Number Publication Date
CN1680325A CN1680325A (zh) 2005-10-12
CN1680325B true CN1680325B (zh) 2011-05-25

Family

ID=34650891

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200510006703.6A Expired - Fee Related CN1680325B (zh) 2004-02-02 2005-02-02 吡啶衍生物的生产方法

Country Status (5)

Country Link
US (1) US7723522B2 (https=)
EP (1) EP1559711B1 (https=)
JP (1) JP4700916B2 (https=)
CN (1) CN1680325B (https=)
DE (1) DE602005007639D1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008093392A1 (ja) 2007-01-29 2008-08-07 Fujifilm Finechemicals Co., Ltd. ２，３'－ビピリジル－６'－オンの製造方法
JP2009286756A (ja) 2008-05-30 2009-12-10 Fujifilm Finechemicals Co Ltd トリアゾール誘導体またはその塩
ES2702487T3 (es) * 2011-06-17 2019-03-01 Nantenergy Inc Líquido iónico que contiene iones sulfonato
CN102977007B (zh) * 2012-12-24 2014-11-05 湖南大学 一种合成3-芳基吡啶衍生物的方法
CN109810052B (zh) * 2017-11-20 2020-06-23 新发药业有限公司 一种高选择性的阿帕替尼的简便制备方法
US11424484B2 (en) 2019-01-24 2022-08-23 Octet Scientific, Inc. Zinc battery electrolyte additive
AR123899A1 (es) * 2020-10-23 2023-01-25 Vertellus Holdings Llc Métodos para elaborar derivados de ácido nicotínico

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1306425A (zh) * 1998-04-24 2001-08-01 麦克公司 合成环加氧酶－2抑制剂的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3032980B1 (ja) 1999-06-14 2000-04-17 三協化学株式会社 ２―ピリジルピリジン誘導体の製造方法
US6124474A (en) * 1999-12-21 2000-09-26 Abbott Laboratories Synthesis of chiral 2-azetidinemethanol compounds
JP2001261653A (ja) 2000-03-17 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の合成法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1306425A (zh) * 1998-04-24 2001-08-01 麦克公司 合成环加氧酶－2抑制剂的方法

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
JEAN－FRANCOIS ET.AL..A GENERAL PREPARATION OF PYRIDINES ANDPYRIDONES VIA THE ANNULATION OF KETONES ANDESTERS.J. ORG. CHEM.66 12.2001,4194-4199.
JEAN-FRANCOIS ET.AL..A GENERAL PREPARATION OF PYRIDINES ANDPYRIDONES VIA THE ANNULATION OF KETONES ANDESTERS.J. ORG. CHEM.66 12.2001,4194-4199. *
KATOH ET.AL..RING TEANSFORMATION REACTIONS OF 1－SUBSTITUTED 2（1H）－PYRIMIDINONES ANDRELATED COMPOUNDS WITH ACTIVE METHYLENECOMPOUNDS.CHEM. PHARM. BULL32 8.1984,2942-2946.
KATOH ET.AL..RING TEANSFORMATION REACTIONS OF 1-SUBSTITUTED 2(1H)-PYRIMIDINONES ANDRELATED COMPOUNDS WITH ACTIVE METHYLENECOMPOUNDS.CHEM. PHARM. BULL32 8.1984,2942-2946. *
NISHIWAK ET. AL...NITROPYRIMIDINONES
NISHIWAK ET. AL...NITROPYRIMIDINONES *
SYNTHETIC EQUIVALENTS OFDIFORMYLAMINE AND NITROMALONALDEHYDE.SYNTHESIS11.1997,1277-1280.
SYNTHETIC EQUIVALENTS OFDIFORMYLAMINE AND NITROMALONALDEHYDE.SYNTHESIS11.1997,1277-1280. *

Also Published As

Publication number Publication date
JP2005213239A (ja) 2005-08-11
CN1680325A (zh) 2005-10-12
JP4700916B2 (ja) 2011-06-15
DE602005007639D1 (de) 2008-08-07
US20050171355A1 (en) 2005-08-04
US7723522B2 (en) 2010-05-25
EP1559711A1 (en) 2005-08-03
EP1559711B1 (en) 2008-06-25

Similar Documents

Publication Publication Date Title
EP3398952B1 (en) Synthesis process of ruxolitinib
Wang et al. One‐Pot Three‐Component Synthesis of Spirooxindoles Catalyzed by Hexamethylenetetramine in Water
JP2002537223A (ja) サイクリン依存性キナーゼ阻害剤として有用な６−置換ピラゾロ［３，４−ｄ］ピリミジン−４−オン類
Perner et al. 5, 6, 7-trisubstituted 4-aminopyrido [2, 3-d] pyrimidines as novel inhibitors of adenosine kinase
Ablajan et al. An efficient four-component, one-pot synthesis of 6-Amino-4-Aryl-3-Methyl-2, 4-Dihydropyrano [2, 3-C] Pyrazole-5-Carbonitriles under phase-transfer catalyst
CN1680325B (zh) 吡啶衍生物的生产方法
CN101139339A (zh) 1-吡啶-4-基-吲哚化合物的制备方法
CN104725318A (zh) 一种爱曲伯帕的合成方法
Lu et al. A One‐pot, Efficient Synthesis of Polyfunctionalized Pyrido [2, 3‐d] pyrimidines and Uncyclized Adducts by Aldehydes, 1, 3‐Dicarbonyl Compounds, and 6‐Aminouracils
Samzadeh‐Kermani et al. A catalytic route to pyrrole derivatives via copper‐catalyzed multicomponent reaction
CN115872914A (zh) 一种取代吡咯类化合物的合成方法
Zhuo et al. Visible-Light-Induced C (sp3)-H Activation for Minisci Alkylation of Pyrimidines Using CHCl3 as Radical Source and Oxidant
Vijayasankar et al. Amorphous mesoporous iron aluminophosphate catalyst for the synthesis of 1, 5-benzodiazepines
Tumkevicius et al. Synthesis of novel thieno-and pyrrolo [2, 3-d] pyrimidines peri-fused with pyrimidine, 1, 4-diazepine and 1, 4-thiazepine rings
Chen et al. Methyl-α-D-glucopyranoside as green ligand for selective copper-catalyzed N-arylation
EP3480187B1 (en) Method for preparing indenoisoquinoline derivatives
Song et al. Synthesis of new 1‐phenylthieno [1, 2, 4] triazolo [4, 3‐a] pyrimidin‐5 (4H)‐one derivatives
Rajmane et al. C18‐DABCO‐AA: A Novel Brønsted Acidic Gemini Surfactant for the Environmental Benign Synthesis of 2, 3‑Dihydroquinazolin‑4 (1H)‑ones in Water at Ambient Temperature
Rahmati et al. Synthesis of N-alkyl-2-aryl-5H-imidazo [1, 2-b] pyrazol-3-amines by a three-component condensation reaction
Stroganova et al. Some transformations of tertiary N-furfurylamides of aromatic and heteroaromatic carboxylic acids under acidic conditions
CN110218192B (zh) 一种2-氨基-4,6-二甲氧基嘧啶的制备方法
Kobayashi et al. Synthesis of 4-(1-Dialkylaminoalkyl)-pyrrolo (1, 2-a) quinoxalines
Babu et al. One Pot Multicomponent Green Synthesis of Triaryl Imidazoles Catalysed by Nano Nickel Cobalt Ferrite
CN103288757A (zh) 6-氨基-7-羟基-3,4-二氢喹唑啉-4-酮的制备方法
Gadde et al. Synthesis of a Novel Library of 1-Substituted Pyrido [1, 2-a] benzimidazoles

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CP01 Change in the name or title of a patent holder

Address after: Japan Osaka

Patentee after: Fujifilm Wako Pure Chemical Industries, Ltd.

Address before: Japan Osaka

Patentee before: WAKO PURE CHEMICAL INDUSTRIES, Ltd.

CP01 Change in the name or title of a patent holder
TR01 Transfer of patent right

Effective date of registration: 20180710

Address after: Japan Osaka

Patentee after: WAKO PURE CHEMICAL INDUSTRIES, Ltd.

Address before: Tokyo, Japan

Patentee before: Fujifilm Finechemicals Co.,Ltd.

TR01 Transfer of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110525

Termination date: 20220202

CF01 Termination of patent right due to non-payment of annual fee