CN1653068A - 新的二氮杂双环联芳基衍生物 - Google Patents

新的二氮杂双环联芳基衍生物 Download PDF

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Publication number
CN1653068A
CN1653068A CNA03810198XA CN03810198A CN1653068A CN 1653068 A CN1653068 A CN 1653068A CN A03810198X A CNA03810198X A CN A03810198XA CN 03810198 A CN03810198 A CN 03810198A CN 1653068 A CN1653068 A CN 1653068A
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group
alkyl
cycloalkyl
biaryl derivatives
monocyclic heterocycles
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Chinese (zh)
Inventor
D·彼得斯
G·M·奥尔森
E·O·尼尔森
T·D·约金森
P·K·阿林格
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNA03810198XA 2002-05-07 2003-05-06 新的二氮杂双环联芳基衍生物 Pending CN1653068A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200200692 2002-05-07
DKPA200200692 2002-05-07
DKPA200201739 2002-11-11
DKPA200201739 2002-11-11

Publications (1)

Publication Number Publication Date
CN1653068A true CN1653068A (zh) 2005-08-10

Family

ID=29421783

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA03810198XA Pending CN1653068A (zh) 2002-05-07 2003-05-06 新的二氮杂双环联芳基衍生物

Country Status (12)

Country Link
US (1) US7300933B2 (https=)
EP (1) EP1506200B1 (https=)
JP (1) JP2005524713A (https=)
CN (1) CN1653068A (https=)
AT (1) ATE348831T1 (https=)
AU (1) AU2003223927B2 (https=)
CA (1) CA2480488A1 (https=)
DE (1) DE60310548T2 (https=)
DK (1) DK1506200T3 (https=)
MX (1) MXPA04010966A (https=)
NZ (1) NZ535642A (https=)
WO (1) WO2003094831A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102648202A (zh) * 2009-12-07 2012-08-22 塔加西普特公司 作为神经元烟碱乙酰胆碱受体配体的3,6-二氮杂双环[3.1.1]庚烷
CN102816165A (zh) * 2005-09-23 2012-12-12 雅培制药有限公司 氨基-氮杂-金刚烷衍生物和使用方法
CN104936955A (zh) * 2013-01-23 2015-09-23 诺华股份有限公司 噻二唑类似物以及治疗与smn缺乏相关的病症的方法

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DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
US20050065178A1 (en) * 2003-09-19 2005-03-24 Anwer Basha Substituted diazabicycloakane derivatives
US7399765B2 (en) * 2003-09-19 2008-07-15 Abbott Laboratories Substituted diazabicycloalkane derivatives
TW200534855A (en) * 2004-01-13 2005-11-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
US7582631B2 (en) * 2004-01-14 2009-09-01 Amgen Inc. Substituted heterocyclic compounds and methods of use
WO2005087236A1 (en) * 2004-03-11 2005-09-22 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
EP1725238A4 (en) * 2004-03-17 2009-04-01 Glaxo Group Ltd M 3 MUSCARINACETYLCHOLINE RECEPTOR ANTAGONISTS
EP1809282B1 (en) 2004-10-18 2013-01-09 Amgen, Inc Thiadiazole compounds and methods of use
EP1866314B1 (en) 2005-02-16 2010-09-15 NeuroSearch A/S Novel diazabicyclic aryl derivatives and their medical use
WO2006087306A2 (en) * 2005-02-16 2006-08-24 Neurosearch A/S Diazabicyclic aryl derivatives and their use as cholinergic ligands at the nicotinic acetylcholine receptors
US7662812B2 (en) * 2005-02-16 2010-02-16 Neurosearch A/S Diazabicyclic aryl derivatives and their use as chinolinergic ligands at nicotinic acetylcholine receptors
ATE473978T1 (de) * 2005-12-06 2010-07-15 Neurosearch As Neue diazabicyclische arylderivate und medizinische verwendung dafür
JO3019B1 (ar) 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
US8314119B2 (en) 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
US7919504B2 (en) 2007-07-17 2011-04-05 Amgen Inc. Thiadiazole modulators of PKB
EP2173728A2 (en) 2007-07-17 2010-04-14 Amgen Inc. Heterocyclic modulators of pkb
CA2697974C (en) * 2007-10-18 2015-06-30 Janssen Pharmaceutica Nv Trisubstituted 1,2,4-triazoles
JO2784B1 (en) * 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
WO2009115547A1 (en) 2008-03-19 2009-09-24 Janssen Pharmaceutica Nv Trisubstituted 1, 2, 4 -triazoiies as nicotinic acetylcholine receptor modulators
AR071763A1 (es) 2008-05-09 2010-07-14 Janssen Pharmaceutica Nv Pirazoles trisustituidos, composiciones farmaceuticas que los contienen, y usos de los mismos en el tratamiento de trastornos neurologicos y psiquiatricos
PE20170923A1 (es) 2010-05-17 2017-07-12 Forum Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado
PE20131394A1 (es) 2010-09-23 2014-01-11 Abbvie Inc Monohidrato de derivados de aza-adamantano
EP3461481A1 (en) 2012-05-08 2019-04-03 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function
TWI553941B (zh) * 2013-10-29 2016-10-11 Ｌｇ化學股份有限公司 凝膠聚合物電解質以及含有該電解質之鋰二次電池

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Publication number Priority date Publication date Assignee Title
US5478939A (en) * 1994-07-20 1995-12-26 American Cyanamid Company (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives
FR2786769B1 (fr) * 1998-12-04 2002-10-25 Synthelabo Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique
ES2305373T3 (es) * 1999-01-29 2008-11-01 Abbott Laboratories Derivados diazabiciclicos como ligandos del receptor nicotinico de la acetilcolina.
JP2003534344A (ja) 2000-05-25 2003-11-18 ターガセプト，インコーポレイテッド ニコチン性コリン受容体リガンドとしてのヘテロアリールジアザビシクロアルカン

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102816165A (zh) * 2005-09-23 2012-12-12 雅培制药有限公司 氨基-氮杂-金刚烷衍生物和使用方法
CN102648202A (zh) * 2009-12-07 2012-08-22 塔加西普特公司 作为神经元烟碱乙酰胆碱受体配体的3,6-二氮杂双环[3.1.1]庚烷
CN104936955A (zh) * 2013-01-23 2015-09-23 诺华股份有限公司 噻二唑类似物以及治疗与smn缺乏相关的病症的方法
CN104936955B (zh) * 2013-01-23 2018-08-28 诺华股份有限公司 噻二唑类似物以及治疗与smn缺乏相关的病症的方法

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EP1506200A2 (en) 2005-02-16
AU2003223927A1 (en) 2003-11-11
DK1506200T3 (da) 2007-04-10
WO2003094831A3 (en) 2004-01-15
US7300933B2 (en) 2007-11-27
AU2003223927B2 (en) 2009-12-17
DE60310548D1 (de) 2007-02-01
DE60310548T2 (de) 2007-05-10
CA2480488A1 (en) 2003-11-20
US20050131236A1 (en) 2005-06-16
WO2003094831A2 (en) 2003-11-20
JP2005524713A (ja) 2005-08-18
ATE348831T1 (de) 2007-01-15
MXPA04010966A (es) 2005-01-25
EP1506200B1 (en) 2006-12-20
NZ535642A (en) 2006-10-27

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