CN1650888A - Povidone-iodine suppository for treating dairy cattle endometritis - Google Patents
Povidone-iodine suppository for treating dairy cattle endometritis Download PDFInfo
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- CN1650888A CN1650888A CN 200410016141 CN200410016141A CN1650888A CN 1650888 A CN1650888 A CN 1650888A CN 200410016141 CN200410016141 CN 200410016141 CN 200410016141 A CN200410016141 A CN 200410016141A CN 1650888 A CN1650888 A CN 1650888A
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- suppository
- povidone iodine
- povidone
- endometritis
- iodine
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Abstract
A suppository of povidone iodine for treating the endometritis of milk cow features its slow release function for durable action.
Description
Technical field:
The invention belongs to the veterinary drug technical field.Be specifically related to a kind of povidone iodine suppository for the treatment of cow endometritis.
Background technology:
Run into an insoluble problem in the raising of milch cow, most milch cow suffers from endometritis and mastitis, and usually recurrence.
Along with people to living environment and food requirement, advocate " pollution-free food ", " no antimicrobial drug is suckled ".And treat at present that the cow endometritis conventional therapy adopts flushing and with reperfusion modes such as antimicrobial drugs, but liquid medicine exerted duty by cattle uterus easily and squeezes out, and action time is short, can not give full play to drug effect, influences therapeutic effect.Simultaneously because of a large amount of antibiotic that use.Easily develop immunity to drugs on the one hand, also causing has antibiotic remains in the milk, and the people drinks and contains antibiotic milk and also can bring adverse consequences.
According to the literature, the complex of povidone iodine---iodine and vinylpyrrolidone " iodine foam " has broad-spectrum antiseptic, anti-inflammatory analgetic effect, can shorten sick cattle convalescence.1998～1999 years under surgery teaching and research room of obstetrics of Saratov agriculture university under animal house and " Ni Tafaermu " inner joint-stock company laboratory and Sa Ertuofu state thunder continue that some production units of Gao Erqu have carried out the toxicity, pharmacokinetics of relevant iodine foam and to the research of preventive and therapeutic effect of suppurative Catarrhal endometritis in puerperal.Iodine foam preparation (suppository) is the high-efficiency preparation of control cow puerperal endometritis.Confirm this product stable performance, preserve 18 months its physicochemical properties and active substance function continuously and do not change.This product does not have local irritant effect, sensitization turns usefulness, allergy effect, fetal toxicity effect, carcinogenesis, mutagenesis into.This product effectively (activity) composition (iodine polyvinylpyrrolidone) can not discharged from uterine cancer cell in round the clock 2.This product can activate the contractile function in uterus, has antimicrobial and antifungal, antiinflammatory and analgesic effect, can also improve intrauterine hypertrophy process.See " new drug-iodine foam of control cattle endometritis " " veterinary drug and feed additive " the 3rd phase of calendar year 2001.
Summary of the invention:
Technical problem to be solved by this invention is to overcome above-mentioned weak point, studies a kind of drug residue free, novel form easy to use.
The invention provides a kind of povidone iodine suppository that is used for the treatment of cow endometritis.
The invention provides a kind of povidone iodine suppository that is used for the treatment of cow endometritis.This suppository is the % meter by weight, comprises povidone iodine 5%～10%; Suppository base 94～89%; Stabilizing agent and remover 1% are formed.
Suppository of the present invention is to be main medicine and suppository base with povidone iodine, and semi-synthetic fatty acid glyceride is arranged; Oleum theobromatis, Myrj 45, hydrogenated vegetable oil, glycerin gelatine, polyethylene glycols or other suitable materials, stabilizing agent and releasing agent (as polyalcohol ether, mineral tallow) form through fusing, mixing, injection molding, cooling, packing.This suppository can spin different shapes such as mallet shape, bullet shaped.
Suppository of the present invention has overcome liquid medicine to be squeezed out by cattle uterus easily, and long action time can be killed various morbific pathogen in uterus effectively, and sterilizing power is strong, and bactericidal range is wide.Nonirritant, adaptability is good, and polyvidone has film property simultaneously, can promote wound surface and wound healing.Because the suppository that adopts the high-quality host material to make easily melts, active ingredient is fully contacted with wound surface and wound in addition, therapeutic effect obviously improves.
Description of drawings:
The typical shape of the polyvidone allusion quotation suppository of Fig. 1, treatment cow endometritis
The specific embodiment:
Embodiment 1,
Povidone iodine 5.00%
Suppository base 94.00%
Stabilizing agent, remover 1.00%
Embodiment 2,
Povidone iodine 10.00%
Suppository base 89.00%
Stabilizing agent, remover 1.00%
Claims (3)
1, a kind of povidone iodine suppository for the treatment of cow endometritis is characterized in that this suppository % meter by weight, comprises povidone iodine 5%～10%; Suppository base 94～89%; Stabilizing agent and remover 1% are formed.
2, a kind of povidone iodine suppository for the treatment of cow endometritis according to claim 1 is characterized in that wherein said suppository base is semi-synthetic fatty acid glyceride, oleum theobromatis, polyoxyethylene 8 stearate, hydrogenated vegetable oil, does not sweetly have gelatin or a Polyethylene Glycol; Remover is a mineral tallow, and stabilizing agent is a polyalcohol ether.
3, a kind of povidone iodine suppository for the treatment of cow endometritis according to claim 1 is characterized in that this suppository is for spinning mallet shape or bullet shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410016141 CN1650888A (en) | 2004-02-05 | 2004-02-05 | Povidone-iodine suppository for treating dairy cattle endometritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410016141 CN1650888A (en) | 2004-02-05 | 2004-02-05 | Povidone-iodine suppository for treating dairy cattle endometritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1650888A true CN1650888A (en) | 2005-08-10 |
Family
ID=34868219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410016141 Pending CN1650888A (en) | 2004-02-05 | 2004-02-05 | Povidone-iodine suppository for treating dairy cattle endometritis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1650888A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335120A (en) * | 2011-11-11 | 2012-02-01 | 武汉回盛生物科技有限公司 | Povidone iodine effervescent suppository for treating hysteritis and vaginitis of sows |
| CN102846725A (en) * | 2012-03-21 | 2013-01-02 | 华南农业大学 | Compound povidone iodine suppository and preparation method and application thereof |
| RU2528916C1 (en) * | 2013-03-12 | 2014-09-20 | Государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии Российской академии сельскохозяйственных наук (ГНУ ВНИВИПФиТ Россельхозакадемии) | Method of comprehensive treatment of cows with postpartum endometritis |
| RU2603482C1 (en) * | 2015-07-14 | 2016-11-27 | Федеральное государственное бюджетное научное учреждение Всероссийский научно-исследовательский институт генетики и разведения сельскохозяйственных животных | Bolus calcium-intensive plus |
-
2004
- 2004-02-05 CN CN 200410016141 patent/CN1650888A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102335120A (en) * | 2011-11-11 | 2012-02-01 | 武汉回盛生物科技有限公司 | Povidone iodine effervescent suppository for treating hysteritis and vaginitis of sows |
| CN102846725A (en) * | 2012-03-21 | 2013-01-02 | 华南农业大学 | Compound povidone iodine suppository and preparation method and application thereof |
| CN102846725B (en) * | 2012-03-21 | 2015-02-25 | 华南农业大学 | Compound povidone iodine suppository and preparation method and application thereof |
| RU2528916C1 (en) * | 2013-03-12 | 2014-09-20 | Государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии Российской академии сельскохозяйственных наук (ГНУ ВНИВИПФиТ Россельхозакадемии) | Method of comprehensive treatment of cows with postpartum endometritis |
| RU2603482C1 (en) * | 2015-07-14 | 2016-11-27 | Федеральное государственное бюджетное научное учреждение Всероссийский научно-исследовательский институт генетики и разведения сельскохозяйственных животных | Bolus calcium-intensive plus |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |