CN108126003A - A kind of female private part bacteriostatic gel and preparation method thereof - Google Patents

A kind of female private part bacteriostatic gel and preparation method thereof Download PDF

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Publication number
CN108126003A
CN108126003A CN201810104891.3A CN201810104891A CN108126003A CN 108126003 A CN108126003 A CN 108126003A CN 201810104891 A CN201810104891 A CN 201810104891A CN 108126003 A CN108126003 A CN 108126003A
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CN
China
Prior art keywords
folium artemisiae
artemisiae argyi
private part
female private
propylene glycol
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810104891.3A
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Chinese (zh)
Inventor
韩杨
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United States Biological Technology (shanghai) Co Ltd
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United States Biological Technology (shanghai) Co Ltd
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Priority to CN201810104891.3A priority Critical patent/CN108126003A/en
Publication of CN108126003A publication Critical patent/CN108126003A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes

Abstract

The invention discloses a kind of female private part bacteriostatic gels and preparation method thereof, are made of the raw material of following parts by weight:Deionized water, folium artemisiae argyi take liquid, oriental cherry odor type, ASAP, 407,188, propylene glycol, fermentation of bacillus product;It is added to folium artemisiae argyi, a kind of plant that folium artemisiae argyi almost grows on trees in south China, prove that folium artemisiae argyi is a kind of drug of anti-bacteria and anti-virus according to modern medicine pharmacology, experiment in vitro proves, Blumea oil has inhibiting effect to coccus and most of gram-Negative bacillus, wormwood plays the role of inhibition and killing to germ, female private part bacteriostatic gel is a is convenient for carrying, the simple and convenient drug with medical miscellaneous function, it is simple for process, it is of low cost, it is environmentally protective, it is with short production cycle, it is suitble to high-volume industrial production, gelling agent has high-efficiency antimicrobial, bacteriostasis property, performance is stablized, there is therapeutic effect to gynecological diseases such as vaginitis and cervical erosion, and cleanable nursing female private part, it is antipruritic, remove peculiar smell and lubrication.

Description

A kind of female private part bacteriostatic gel and preparation method thereof
Technical field
The present invention relates to a kind of female private part bacteriostatic gel, more particularly, to a kind of female private part bacteriostatic gel and its Preparation method.
Background technology
Gynaecological imflammation be primarily referred to as female sex organ by various pathogenic bacteria invasion infection after occur it is acute or slow Property Inflammation Inflammation is not treated in time, and except that may lead to inflammation in addition to each physiological site is mutually spread with cross-infection, can be brought perhaps More complication such as gynecological tumor and infertile.
Gynaecological imflammation mainly includes:Vaginitis:Vaginal fluid increases and pruritus vulvue or has scorching hot, pain, intercourse pain Deng.Secretion typical feature is thin purulence, yellow green foam-like, has stink.If merging urinary tract infection, can there are frequent micturition, odynuria, Sometimes see blood urine.Vulvitis:For skin of vulva itch, burn feeling and pain, in activity, sexual intercourse and urination postemphasis.Acute stage Redness, has scratch at hyperemia.Cracking, mossization occur for chronic inflammation, sufferings, vulva.Pelvic infecton:Divide acute and chronic.Acute onset It is anxious, development is fast, shows as high fever, abdominal pain and distension, with nausea,vomiting,diarrhea, shiver, have a headache.It is chronic that show as whole body weary It is more serious between power, especially lassitude, menstruation and after sexual intercourse.Cervicitis:There is symptom to be mainly shown as that vaginal fluid increases More, in coctum, the stimulation of vaginal fluid can cause hidden cloudy itch and burning heat sensation, also may occur in which intermenstrual bleeding, sexual intercourse The symptoms such as bleeding afterwards.In addition, often there are lower urinary tract symptoms, such as urgent urination, frequent micturition, odynuria.Salpingitis:Lower abdomen secret anguish, tenesmus Sense, menoxenia, dysmenorrhoea, leucorrhea increasing, some patients also can be without any subjective symptoms in addition to infertile.Bartholinitis:It is common In the women of child-bearing age.It is because greater vestibular gland is caused by the bacterium infections such as staphylococcus, streptococcus, Escherichia coli, causes acute more Inflammation.Different treatment methods are taken according to various disease.If as caused by infection, it should be according to the microorganism of infection using not Same antibacterial, antimycotic or antiviral drug treatment.When acute inflammation breaks out, it need to lie up, determine pathogen, root Antibiotic is selected according to pathogen, relative medicine hip bath also can be selected.Patients with chronic diseases should be paid attention to eliminating the cause of disease.
Gelling agent refers to drug and the latex glop or semisolid of uniform, suspension or emulsion-type made of suitable auxiliary material Preparation.Gelling agent limit is used locally for skin and body cavity such as nasal cavity, vagina and rectum.At present, the type of gelling agent is various on the market, It is directed to that female private part bacteriostatic gel product is less, and irregular for treating antibacterial effect, function is single, very much There are significant limitations for gelling agent product bacteriostasis, therefore it provides a kind of female private part can be antibacterial, antipruritic, also may be used To remove the female private part bacteriostatic gel of peculiar smell, lubrication.
Invention content
The technical problem to be solved by the present invention is to overcome the deficiencies in the prior art, and providing a kind of female private part of offer can It is antibacterial, antipruritic, peculiar smell, the female private part bacteriostatic gel lubricated and preparation method thereof can also be removed, so as to solve the above problems.
To achieve the above object, the present invention provides following technical solution:A kind of female private part bacteriostatic gel, by following heavy Measure the raw material composition of part:Deionized water, folium artemisiae argyi take liquid, oriental cherry odor type, ASAP, 407,188, propylene glycol, fermentation of bacillus Product;
Preferably, it is made of the raw material of following parts by weight:57.99% deionized water, 15% folium artemisiae argyi take liquid, 0.01% oriental cherry odor type, The propylene glycol of 1%ASAP, 20%407,1%188,4%, 1% fermentation of bacillus product;
Preferably, 15% folium artemisiae argyi takes liquid to include following component:1 gram of powder dilution, the water of 100ml.
Preferably, the pH value is 6.5 or so.
Preferably, a kind of preparation method of female private part bacteriostatic gel, includes the following steps:
Step 1;Prepare material:Proportionally prepare:57.99% deionized water, 15% folium artemisiae argyi take liquid, 0.01% oriental cherry odor type, The propylene glycol of 1%ASAP, 20%407,1%188,4%, 1% fermentation of bacillus product.
Step 2;The powder dilution that liquid adds 1 gram is taken in 15% folium artemisiae argyi and the water of 100ml is first got sample, then squeezed out It has some on paper handkerchief, tests repeatedly, until color is had not a particle of on paper handkerchief, as standard;0.01% oriental cherry odor type is first Some samples are got, confirm specifically to match, as long as a little light faint scent is smelt, as standard;
Step 3;57.99% deionized water, 15% folium artemisiae argyi are taken into liquid, 0.01% oriental cherry odor type mixed dissolution, 1%ASAP sides are launched Side is quickly stirred, and mixing time is 5 minutes.
Step 4;Addition 20%407,1%188, first gets sample, then fills a cup of warm water, progress is filling, will be canned Pipe is put into warm water, is tested whether that moment solidifies, is then steeped an evening.
Step 5;Prepare antibacterial peptide, prepare 50 degree of warm water, antibacterial peptide is added to inside 50 degree of warm water, Zhi Daorong It is transparent to solve, then adds 4% propylene glycol, is then stirred until stirring evenly.
Step 6;It checks whether 407,188 bubble open, waits after bubbling open completely, by 4% propylene glycol, 1% fermentation of bacillus product Dispensing is gone down, and is then stirred.
Step 7;After addition then stirring carries out filling until stirring evenly.
Compared with prior art, the beneficial effects of the invention are as follows:
1st, female private part bacteriostatic gel of the invention and preparation method thereof, is added to folium artemisiae argyi, folium artemisiae argyi is a kind of pharmacological property temperature bath Chinese medicine, a kind of plant that folium artemisiae argyi almost grows on trees in south China, products material is sufficient, and cost is not high, suitable for popular wide General batch production proves that folium artemisiae argyi is a kind of drug of anti-bacteria and anti-virus according to modern medicine pharmacology, and experiment in vitro proves, Blumea oil pair Coccus and most of gram-Negative bacillus have inhibiting effect, and wormwood plays the role of inhibition and killing to germ.
2nd, female private part bacteriostatic gel of the invention be it is a be convenient for carrying, simple and convenient has medical treatment auxiliary work( The drug of energy, it is simple for process, of low cost, environmentally protective, with short production cycle, it is suitble to high-volume industrial production, has great Application prospect.
3rd, female private part bacteriostatic gel of the invention has high-efficiency antimicrobial, bacteriostasis property, and bio-safety is nontoxic, performance Stablize, to vaginitis(Bacterial vaginosis BV, monilial vaginitis, Combination vaginitis, vulvitis)With the woman such as cervical erosion Section's disease has a therapeutic effect, and cleanable nursing female private part, anti-inflammatory it is antibacterial, it is antipruritic, remove peculiar smell and lubrication.
Specific embodiment
Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only It is part of the embodiment of the present invention, instead of all the embodiments, based on the embodiments of the present invention, ordinary skill people Member's all other embodiments obtained without making creative work, shall fall within the protection scope of the present invention.
The present invention provides a kind of technical solution, and a kind of female private part bacteriostatic gel is made of the raw material of following parts by weight: Deionized water, folium artemisiae argyi take liquid, oriental cherry odor type, ASAP, 407,188, propylene glycol, fermentation of bacillus product;
Preferably, it is made of the raw material of following parts by weight:57.99% deionized water, 15% folium artemisiae argyi take liquid, 0.01% oriental cherry odor type, The propylene glycol of 1%ASAP, 20%407,1%188,4%, 1% fermentation of bacillus product;
Preferably, 15% folium artemisiae argyi takes liquid to include following component:1 gram of powder dilution, the water of 100ml.
Preferably, the pH value is 6.5 or so.
Preferably, a kind of preparation method of female private part bacteriostatic gel, includes the following steps:
Step 1;Prepare material:Proportionally prepare:57.99% deionized water, 15% folium artemisiae argyi take liquid, 0.01% oriental cherry odor type, The propylene glycol of 1%ASAP, 20%407,1%188,4%, 1% fermentation of bacillus product.
Step 2;The powder dilution that liquid adds 1 gram is taken in 15% folium artemisiae argyi and the water of 100ml is first got sample, then squeezed out It has some on paper handkerchief, tests repeatedly, until color is had not a particle of on paper handkerchief, as standard;0.01% oriental cherry odor type is first Some samples are got, confirm specifically to match, as long as a little light faint scent is smelt, as standard;
Step 3;57.99% deionized water, 15% folium artemisiae argyi are taken into liquid, 0.01% oriental cherry odor type mixed dissolution, 1%ASAP sides are launched Side is quickly stirred, and mixing time is 5 minutes.
Step 4;Addition 20%407,1%188, first gets sample, then fills a cup of warm water, progress is filling, will be canned Pipe is put into warm water, is tested whether that moment solidifies, is then steeped an evening.
Step 5;Prepare antibacterial peptide, prepare 50 degree of warm water, antibacterial peptide is added to inside 50 degree of warm water, Zhi Daorong It is transparent to solve, then adds 4% propylene glycol, is then stirred until stirring evenly.
Step 6;It checks whether 407,188 bubble open, waits after bubbling open completely, by 4% propylene glycol, 1% fermentation of bacillus product Dispensing is gone down, and is then stirred.
Step 7;After addition then stirring carries out filling until stirring evenly.
1st, female private part bacteriostatic gel of the invention and preparation method thereof, is added to folium artemisiae argyi, folium artemisiae argyi is a kind of pharmacological property temperature The Chinese medicine of bath, a kind of plant that folium artemisiae argyi almost grows on trees in south China, products material is sufficient, and cost is not high, suitable for public Change batch production extensively, prove that folium artemisiae argyi is a kind of drug of anti-bacteria and anti-virus according to modern medicine pharmacology, experiment in vitro proves, folium artemisiae argyi Oil has inhibiting effect to coccus and most of gram-Negative bacillus, and wormwood plays the role of inhibition and killing to germ.
2nd, female private part bacteriostatic gel of the invention be it is a be convenient for carrying, simple and convenient has medical treatment auxiliary work( The drug of energy, it is simple for process, of low cost, environmentally protective, with short production cycle, it is suitble to high-volume industrial production, has great Application prospect.
3rd, female private part bacteriostatic gel of the present invention has high-efficiency antimicrobial, bacteriostasis property, and bio-safety is nontoxic, and performance is steady It is fixed, to vaginitis(Bacterial vaginosis BV, monilial vaginitis, Combination vaginitis, vulvitis)With the gynaecology such as cervical erosion Disease has a therapeutic effect, and cleanable nursing female private part, anti-inflammatory it is antibacterial, it is antipruritic, remove peculiar smell and lubrication.
Finally it should be noted that:The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used To modify to the technical solution recorded in foregoing embodiments or carry out equivalent replacement to which part technical characteristic, All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in the present invention's Within protection domain.

Claims (5)

1. a kind of female private part bacteriostatic gel, which is characterized in that be made of the raw material of following parts by weight:Deionized water, folium artemisiae argyi Take liquid, oriental cherry odor type, ASAP, 407,188, propylene glycol, fermentation of bacillus product.
2. a kind of female private part bacteriostatic gel according to claims 1, which is characterized in that by the original of following parts by weight Material composition:57.99% deionized water, 15% folium artemisiae argyi take liquid, 0.01% oriental cherry odor type, 1%ASAP, 20%407,1%188, 4% propylene glycol, 1% fermentation of bacillus product.
3. a kind of female private part bacteriostatic gel according to claims 1, which is characterized in that 15% folium artemisiae argyi takes liquid Body includes following component:1 gram of powder dilution, the water of 100ml.
4. a kind of female private part bacteriostatic gel according to claims 1, which is characterized in that the pH value is on 6.5 left sides It is right.
5. the preparation method of a kind of female private part bacteriostatic gel as described in claim 1-4, which is characterized in that including following Step:
Step 1;Prepare material:Proportionally prepare:57.99% deionized water, 15% folium artemisiae argyi take liquid, 0.01% oriental cherry fragrant Type, the propylene glycol of 1%ASAP, 20%407,1%188,4%, 1% fermentation of bacillus product.
Step 2;The powder dilution that liquid adds 1 gram is taken in 15% folium artemisiae argyi and the water of 100ml is first got sample, then extruded A little on paper handkerchief, test repeatedly, until color is had not a particle of on paper handkerchief, as standard;0.01% oriental cherry odor type is first Some samples are got, confirm specifically to match, as long as a little light faint scent is smelt, as standard;
Step 3;57.99% deionized water, 15% folium artemisiae argyi are taken into liquid, 0.01% oriental cherry odor type mixed dissolution, 1%ASAP sides It launches side quickly to stir, mixing time is 5 minutes.
Step 4;Addition 20%407,1%188, first gets sample, then fills a cup of warm water, progress is filling, by canned pipe Son is put into warm water, is tested whether that moment solidifies, is then steeped an evening.
Step 5;Prepare antibacterial peptide, prepare 50 degree of warm water, antibacterial peptide is added to inside 50 degree of warm water, until being dissolved as It is transparent, then 4% propylene glycol is added, it then stirs until stirring evenly.
Step 6;It checks whether 407,188 bubble open, waits after bubbling open completely, 4% propylene glycol, 1% fermentation of bacillus product are thrown It puts down, then stirs.
Step 7;After addition then stirring carries out filling until stirring evenly.
CN201810104891.3A 2018-02-02 2018-02-02 A kind of female private part bacteriostatic gel and preparation method thereof Pending CN108126003A (en)

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Application Number Priority Date Filing Date Title
CN201810104891.3A CN108126003A (en) 2018-02-02 2018-02-02 A kind of female private part bacteriostatic gel and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110179839A (en) * 2019-07-03 2019-08-30 上海美哈医药科技有限公司 A kind of anti-myomata gelling agent and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110179839A (en) * 2019-07-03 2019-08-30 上海美哈医药科技有限公司 A kind of anti-myomata gelling agent and preparation method thereof

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Application publication date: 20180608

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